Principles of Geriatric Medicine and Gerontology.

Frailty in Older Adults: Evidence for a Phenotype

Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907

Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care

Fried, L. P., Ferrucci, L., Darer, J., Williamson, J. D., & Anderson, G. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.3.m255 · Cited by 4,032

A Study of sexuality and health among older adults in the United States

Lindau, S. T., Schumm, L. P., Laumann, E. O., Levinson, W., O'Muircheartaigh, C. A., & Waite, L. J. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa067423 · Cited by 2,211

Individual-patient monitoring in clinical practice: are available health status surveys adequate?

McHorney, C. A., & Tarlov, A. R. (1995) · Quality of Life Research · doi:10.1007/bf01593882 · Cited by 2,206

Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale

Miller, M. D., Paradis, C. F., Houck, P. R., Mazumdar, S., Stack, J. A., Rifai, A. H., Mulsant, B., & Reynolds, C. F. (1992) · Psychiatry Research · doi:10.1016/0165-1781(92)90005-n · Cited by 1,990

Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study

Feldman, H. A., Longcope, C., Derby, C. A., Johannes, C. B., Araujo, A. B., Coviello, A. D., Bremner, W. J., & McKinlay, J. B. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8201 · Cited by 1,861

Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia

Guralnik, J. M., Eisenstaedt, R. S., Ferrucci, L., Klein, H. G., & Woodman, R. C. (2004) · Blood · doi:10.1182/blood-2004-05-1812 · Cited by 1,450

Phenotype of frailty: characterization in the women's health and aging studies

Bandeen-Roche, K., Xue, Q.-L., Ferrucci, L., Walston, J., Guralnik, J. M., Chaves, P., Zeger, S. L., & Fried, L. P. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.3.262 · Cited by 1,215

Frailty: An Emerging Research and Clinical Paradigm--Issues and Controversies

Bergman, H., Ferrucci, L., Guralnik, J., Hogan, D. B., Hummel, S., Karunananthan, S., & Wolfson, C. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.7.731 · Cited by 1,134

Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment

Fried, L. P., Xue, Q.-L., Cappola, A. R., Ferrucci, L., Chaves, P., Varadhan, R., Guralnik, J. M., Leng, S. X., Semba, R. D., Walston, J. D., et al. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glp076 · Cited by 539

Allostatic load as a predictor of functional decline

Karlamangla, A. S., Singer, B. H., McEwen, B. S., Rowe, J. W., & Seeman, T. E. (2002) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(02)00399-2 · Cited by 483

Enteral tube feeding for older people with advanced dementia

Sampson, E. L., Candy, B., & Jones, L. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007209.pub2 · Cited by 438

Epidemiology and Unique Aspects of Aging and Infectious Diseases

Yoshikawa, T. T. (2000) · Clinical Infectious Diseases · doi:10.1086/313792 · Cited by 392

Social isolation, support, and capital and nutritional risk in an older sample: ethnic and gender differences

Locher, J. L., Ritchie, C. S., Roth, D. L., Baker, P. S., Bodner, E. V., & Allman, R. M. (2005) · Social Science & Medicine · doi:10.1016/j.socscimed.2004.06.023 · Cited by 373

Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly

Cohen, H. J., Harris, T., & Pieper, C. F. (2003) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01484-5 · Cited by 327

Endocrine and inflammatory markers as predictors of frailty

Puts, M. T. E., Visser, M., Twisk, J. W. R., Deeg, D. J. H., & Lips, P. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02355.x · Cited by 316

What do we know about men's help‐seeking and health service use?

Smith, J. A., Braunack‐Mayer, A., & Wittert, G. (2006) · Medical Journal of Australia · doi:10.5694/j.1326-5377.2006.tb00124.x · Cited by 293

Frailty and sarcopenia - newly emerging and high impact complications of diabetes

Sinclair, A. J., Abdelhafiz, A. H., & Rodríguez-Mañas, L. (2017) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2017.05.003 · Cited by 276

Invited Review: Dynamic exercise performance in Masters athletes: insight into the effects of primary human aging on physiological functional capacity

Tanaka, H., & Seals, D. R. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00320.2003 · Cited by 275

Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty

Leng, S. X., Cappola, A. R., Andersen, R. E., Blackman, M. R., Koenig, K., Blair, M., & Walston, J. D. (2004) · Aging Clinical and Experimental Research · doi:10.1007/bf03324545 · Cited by 270

Somatic mutations and aging: a re-evaluation

Vijg, J. (2000) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(99)00202-x · Cited by 243

Dry skin in the elderly: Complexities of a common problem

White-Chu, E. F., & Reddy, M. (2011) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2010.07.005 · Cited by 229

Factors Contributing to Dehydration in Nursing Homes: Inadequate Staffing and Lack of Professional Supervision

Kayser‐Jones, J., Schell, E. S., Porter, C., Barbaccia, J. C., & Shaw, H. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb05198.x · Cited by 208

Ecological momentary assessment in aging research: A critical review

Cain, A. E., Depp, C. A., & Jeste, D. V. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.01.014 · Cited by 164

Health status and suicide in the second half of life

Conwell, Y., Duberstein, P. R., Hirsch, J. K., Conner, K. R., Eberly, S., & Caine, E. D. (2010) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2348 · Cited by 159

Magnitude and patterns of decline in health and function in 1 year affect subsequent 5-year survival

Perera, S., Studenski, S., Chandler, J. M., & Guralnik, J. M. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.7.894 · Cited by 134

Effects of Testosterone and Progressive Resistance Exercise in Healthy, Highly Functioning Older Men With Low-Normal Testosterone Levels

Hildreth, K. L., Barry, D. W., Moreau, K. L., Vande Griend, J., Meacham, R. B., Nakamura, T., Wolfe, P., Kohrt, W. M., Ruscin, J. M., Kittelson, J., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-3695 · Cited by 140

Selecting target conditions for quality of care improvement in vulnerable older adults

Sloss, E. M., Solomon, D. H., Shekelle, P. G., Young, R. T., Saliba, D., MacLean, C. H., Rubenstein, L. Z., Schnelle, J. F., Kamberg, C. J., & Wenger, N. S. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb04691.x · Cited by 132

Factors that may impact on immunosenescence: an appraisal

Ongrádi, J., & Kövesdi, V. (2010) · Immunity & Ageing · doi:10.1186/1742-4933-7-7 · Cited by 128

Benzodiazepines with different half-life and falling in a hospitalized population

Passaro, A., Volpato, S., Romagnoni, F., Manzoli, N., Zuliani, G., & Fellin, R. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00254-7 · Cited by 122

Aging of the Normal Nose in Adults

Edelstein, D. R. (1996) · The Laryngoscope · doi:10.1097/00005537-199609001-00001 · Cited by 115

Risk Factors for Early and Late Mortality in Hospitalized Older Patients: The Continuing Importance of Functional Status

Ponzetto, M., Maero, B., Maina, P., Rosato, R., Ciccone, G., Merletti, F., Rubenstein, L. Z., & Fabris, F. (2003) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/58.11.m1049 · Cited by 109

Sexual Selection and the Male:Female Mortality Ratio

Kruger, D. J., & Nesse, R. M. (2004) · Evolutionary Psychology · doi:10.1177/147470490400200112 · Cited by 115

MANAGEMENT OF SUICIDAL BEHAVIOR IN THE ELDERLY

Conwell, Y. (1997) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70336-1 · Cited by 114

Characterization of age-related changes in natural killer cells during primary influenza infection in mice

Nogusa, S., Ritz, B. W., Kassim, S. H., Jennings, S. R., & Gardner, E. M. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.01.003 · Cited by 111

Selection, Optimization, and Compensation as Developmental Mechanisms of Adaptive Resource Allocation

Riediger, M., Li, S.-C., & Lindenberger, U. (2006) · Handbook of the Psychology of Aging · doi:10.1016/b978-012101264-9/50016-1 · Cited by 99

Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice

Berry, A., Capone, F., Giorgio, M., Pelicci, P. G., de Kloet, E. R., Alleva, E., Minghetti, L., & Cirulli, F. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2006.05.018 · Cited by 81

Pathological changes in frontal cortex from biopsy to autopsy in Alzheimer's disease

Bennett, D. A., Cochran, E. J., Saper, C. B., Leverenz, J. B., Gilley, D. W., & Wilson, R. S. (1993) · Neurobiology of Aging · doi:10.1016/0197-4580(93)90043-b · Cited by 67

Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity

Dilley, T. K., Bowden, G. T., & Chen, Q. M. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(03)00308-2 · Cited by 64

Collaborative planning approach to inform the implementation of a healthcare manager intervention for hispanics with serious mental illness: a study protocol

Cabassa, L. J., Druss, B., Wang, Y., & Lewis-Fernández, R. (2011) · Implementation Science · doi:10.1186/1748-5908-6-80 · Cited by 50

Biological basis of determinants of health

Bortz, W. M. (2005) · American Journal of Public Health · doi:10.2105/ajph.2003.033324 · Cited by 34