ATAC-seq: a method for assaying chromatin accessibility genome-wide

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Chromatin accessibility and the regulatory epigenome

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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

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Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations

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A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

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Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

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Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation

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Chromatin accessibility profiling by ATAC-seq

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Origin and differentiation of human memory CD8 T cells after vaccination

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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Direct promoter repression by BCL11A controls the fetal to adult hemoglobin switch

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Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

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Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

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MultiVI: deep generative model for the integration of multi-modal data

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Acetate Promotes T Cell Effector Function during Glucose Restriction

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Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

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Immune-evasive human islet-like organoids ameliorate diabetes

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Social status alters immune regulation and response to infection in macaques

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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

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α-Ketoglutarate links p53 to cell fate during tumour suppression

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

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Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

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Using single-cell genomics to understand developmental processes and cell fate decisions

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Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

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Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

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Epigenomics of human CD8 T cell differentiation and aging

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Simultaneous measurement of chromatin accessibility, DNA methylation, and nucleosome phasing in single cells

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A transcriptional switch governs fibroblast activation in heart disease

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Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

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Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

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Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

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CoBATCH for High-Throughput Single-Cell Epigenomic Profiling

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Super-enhancers include classical enhancers and facilitators to fully activate gene expression

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Subtype-specific 3D genome alteration in acute myeloid leukaemia

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Interrogation of human hematopoiesis at single-cell and single-variant resolution

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Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons

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Human pluripotent reprogramming with CRISPR activators

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T follicular helper cells in human efferent lymph retain lymphoid characteristics

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Genetics of the human microglia regulome refines Alzheimer’s disease risk loci

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Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

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Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair

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Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

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Analyzing microglial phenotypes across neuropathologies: a practical guide

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Paradoxical changes in innate immunity in aging: recent progress and new directions

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Profiling chromatin states using single-cell itChIP-seq

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Single-cell genomics meets human genetics

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Single-cell epigenomic variability reveals functional cancer heterogeneity

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Genetic architecture of Alzheimer's disease

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A NPAS4–NuA4 complex couples synaptic activity to DNA repair

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A homeostatic Arid1a-dependent permissive chromatin state licenses hepatocyte responsiveness to liver-injury-associated YAP signaling

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Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8

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Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging

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Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

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A tissue injury sensing and repair pathway distinct from host pathogen defense

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Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors

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Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells

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Transcriptional activation of Jun and Fos members of the AP‐1 complex is a conserved signature of immune aging that contributes to inflammaging

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The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output

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VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases

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Association of a common genetic variant with Parkinson’s disease is mediated by microglia

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Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci

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Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming

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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

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