Most cited biochemistry, genetics and molecular biology papers
- Verified
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.
Walczak, H., Miller, R. E., Ariail, K., Gliniak, B., Griffith, T. S., Kubin, M., Chin, W., Jones, J., Woodward, A., Le, T., et al. (1999) · Nature Medicine
Cell death mechanisms and regulationToxin Mechanisms and Immunotoxins
Cited by 2,497
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An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
Corces, M. R., Trevino, A. E., Hamilton, E. G., Greenside, P. G., Sinnott-Armstrong, N. A., Vesuna, S., Satpathy, A. T., Rubin, A. J., Montine, K. S., Wu, B., et al. (2017) · Nature Methods
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 2,496
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Adapting Proteostasis for Disease Intervention
Balch, W. E., Morimoto, R. I., Dillin, A., & Kelly, J. W. (2008) · Science
Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms
Cited by 2,495
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Skeletal muscle fatigue: cellular mechanisms
Allen, D. G., Lamb, G. D., & Westerblad, H. (2008) · Physiological Reviews
Muscle Physiology and DisordersCardiovascular and exercise physiology
Cited by 2,495
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The Placenta Harbors a Unique Microbiome
Aagaard, K., Ma, J., Antony, K. M., Ganu, R., Petrosino, J., & Versalovic, J. (2014) · Science Translational Medicine
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 2,494
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Environmental epigenomics and disease susceptibility
Jirtle, R. L., & Skinner, M. K. (2007) · Nature Reviews Genetics
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 2,492
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Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
Ignotz, R. A., & Massagué, J. (1986) · Journal of Biological Chemistry
TGF-β signaling in diseasesCell Adhesion Molecules Research
Cited by 2,492
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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Jäger, S., Handschin, C., St.-Pierre, J., & Spiegelman, B. M. (2007) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 2,491
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THE SYNAPTIC VESICLE CYCLE
Südhof, T. C. (2004) · Annual Review of Neuroscience
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 2,547
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Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
Ally, A., Balasundaram, M., Carlsen, R., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., et al. (2017) · Cell
Cancer Genomics and DiagnosticsHepatocellular Carcinoma Treatment and Prognosis
Cited by 2,490
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Transcriptional Activation by Tetracyclines in Mammalian Cells
Gossen, M., Freundlieb, S., Bender, G., Müller, G., Hillen, W., & Bujard, H. (1995) · Science
Bacterial Genetics and BiotechnologyGene Regulatory Network Analysis
Cited by 2,488
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Bias in error estimation when using cross-validation for model selection
Varma, S., & Simon, R. (2006) · BMC Bioinformatics
Gene expression and cancer classificationMachine Learning and Data Classification
Cited by 2,485
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The Beclin 1 network regulates autophagy and apoptosis
Kang, R., Zeh, H. J., Lotze, M. T., & Tang, D. (2011) · Cell Death & Differentiation
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 2,485
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Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
Bhattacharyya, A., Chattopadhyay, R., Mitra, S., & Crowe, S. E. (2014) · Physiological Reviews
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 2,484
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MUMmer4: A fast and versatile genome alignment system
Marçais, G., Delcher, A. L., Phillippy, A. M., Coston, R., Salzberg, S. L., & Zimin, A. (2018) · PLOS Computational Biology
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 2,484
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Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.
Bucay, N., Sarosi, I., Dunstan, C. R., Morony, S., Tarpley, J., Capparelli, C., Scully, S., Tan, H. L., Xu, W., Lacey, D. L., et al. (1998) · Genes & Development
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 2,483
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Integrative approaches for large-scale transcriptome-wide association studies
Gusev, A., Ko, A., Shi, H., Bhatia, G., Chung, W., Penninx, B. W. J. H., Jansen, R., de Geus, E. J. C., Boomsma, D. I., Wright, F. A., et al. (2016) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 2,479
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The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing
Nagalakshmi, U., Wang, Z., Waern, K., Shou, C., Raha, D., Gerstein, M., & Snyder, M. (2008) · Science
Genomics and Phylogenetic StudiesRNA Research and Splicing
Cited by 2,479
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Cellular and developmental control of O 2 homeostasis by hypoxia-inducible factor 1α
Iyer, N. V., Kotch, L. E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H., Gassmann, M., Gearhart, J. D., Lawler, A. M., Yu, A. Y., et al. (1998) · Genes & Development
Cancer, Hypoxia, and MetabolismDevelopmental Biology and Gene Regulation
Cited by 2,476
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mRNA-based therapeutics--developing a new class of drugs
Sahin, U., Karikó, K., & Türeci, Ö. (2014) · Nature Reviews Drug Discovery
RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms
Cited by 2,474
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UALCAN: An update to the integrated cancer data analysis platform
Chandrashekar, D. S., Karthikeyan, S. K., Korla, P. K., Patel, H., Shovon, A. R., Athar, M., Netto, G. J., Qin, Z. S., Kumar, S., Manne, U., et al. (2022) · Neoplasia
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 2,473
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Pathological roles of MAPK signaling pathways in human diseases
Kim, E. K., & Choi, E.-J. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 2,472
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Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man
Smith, E. P., Boyd, J., Frank, G. R., Takahashi, H., Cohen, R. M., Specker, B., Williams, T. C., Lubahn, D. B., & Korach, K. S. (1994) · New England Journal of Medicine
Estrogen and related hormone effectsSexual Differentiation and Disorders
Cited by 2,471
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ASTRAL-III: polynomial time species tree reconstruction from partially resolved gene trees
Zhang, C., Rabiee, M., Sayyari, E., & Mirarab, S. (2018) · BMC Bioinformatics
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 2,471
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