Most cited biochemistry, genetics and molecular biology papers
- Verified
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
23andMe Research Team, Lee, J. J., COGENT (Cognitive Genomics Consortium), Social Science Genetic Association Consortium, Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Nguyen-Viet, T. A., et al. (2018) · Nature Genetics
Genetic Associations and EpidemiologyCognitive Abilities and Testing
Cited by 2,470
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Meta-analysis of the heritability of human traits based on fifty years of twin studies
Polderman, T. J. C., Benyamin, B., de Leeuw, C. A., Sullivan, P. F., van Bochoven, A., Visscher, P. M., & Posthuma, D. (2015) · Nature Genetics
Genetic Associations and EpidemiologyCognitive Abilities and Testing
Cited by 2,467
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Epigenetics: A landscape takes shape
Goldberg, A. D., Allis, C. D., & Bernstein, E. (2007) · Cell
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 2,466
- Verified
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Nejman, D., Livyatan, I., Fuks, G., Gavert, N., Zwang, Y., Geller, L. T., Rotter-Maskowitz, A., Weiser, R., Mallel, G., Gigi, E., et al. (2020) · Science
Gut microbiota and healthBacterial Cancer Therapy
Cited by 2,464
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Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Sancak, Y., Bar-Peled, L., Zoncu, R., Markhard, A. L., Nada, S., & Sabatini, D. M. (2010) · Cell
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 2,464
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The role of site accessibility in microRNA target recognition
Kertesz, M., Iovino, N., Unnerstall, U., Gaul, U., & Segal, E. (2007) · Nature Genetics
MicroRNA in disease regulationRNA and protein synthesis mechanisms
Cited by 2,460
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Gut–brain axis: How the microbiome influences anxiety and depression
Foster, J. A., & McVey Neufeld, K.-A. (2013) · Trends in Neurosciences
Gut microbiota and healthTryptophan and brain disorders
Cited by 2,460
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Initial sequence of the chimpanzee genome and comparison with the human genome
The Chimpanzee Sequencing and Analysis Consortium (2005) · Nature
Genomics and Phylogenetic StudiesEvolution and Genetic Dynamics
Cited by 2,459
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The relation between the divergence of sequence and structure in proteins.
Chothia, C., & Lesk, A. M. (1986) · The EMBO Journal
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 2,458
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Microbiota and SCFA in lean and overweight healthy subjects
Schwiertz, A., Taras, D., Schäfer, K., Beijer, S., Bos, N. A., Donus, C., & Hardt, P. D. (2010) · Obesity
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 2,457
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Systematic identification of genomic markers of drug sensitivity in cancer cells
Garnett, M. J., Edelman, E. J., Heidorn, S. J., Greenman, C. D., Dastur, A., Lau, K. W., Greninger, P., Thompson, I. R., Luo, X., Soares, J., et al. (2012) · Nature
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 2,456
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DNA double-strand breaks: signaling, repair and the cancer connection
Khanna, K. K., & Jackson, S. P. (2001) · Nature Genetics
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 2,455
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Thalidomide is an inhibitor of angiogenesis.
D'Amato, R. J., Loughnan, M. S., Flynn, E., & Folkman, J. (1994) · Proceedings of the National Academy of Sciences
Angiogenesis and VEGF in CancerHeterocyclic Compound Synthesis and Bioactivity
Cited by 2,454
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Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
Ieda, M., Fu, J.-D., Delgado-Olguin, P., Vedantham, V., Hayashi, Y., Bruneau, B. G., & Srivastava, D. (2010) · Cell
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 2,454
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Bayesian inference of species trees from multilocus data
Heled, J., & Drummond, A. J. (2010) · Molecular Biology and Evolution
Genomics and Phylogenetic StudiesGenetic diversity and population structure
Cited by 2,453
- Verified
Cancer cell metabolism: warburg and beyond
Hsu, P. P., & Sabatini, D. M. (2008) · Cell
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 2,452
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Globally optimal stitching of tiled 3D microscopic image acquisitions
Preibisch, S., Saalfeld, S., & Tomancak, P. (2009) · Bioinformatics
Cell Image Analysis TechniquesImage Processing Techniques and Applications
Cited by 2,452
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Widespread transcription at neuronal activity-regulated enhancers
Kim, T.-K., Hemberg, M., Gray, J. M., Costa, A. M., Bear, D. M., Wu, J., Harmin, D. A., Laptewicz, M., Barbara-Haley, K., Kuersten, S., et al. (2010) · Nature
Genomics and Chromatin DynamicsCancer-related molecular mechanisms research
Cited by 2,450
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Centering, scaling, and transformations: improving the biological information content of metabolomics data
van den Berg, R. A., Hoefsloot, H. C., Westerhuis, J. A., Smilde, A. K., & van der Werf, M. J. (2006) · BMC Genomics
Metabolomics and Mass Spectrometry StudiesGene expression and cancer classification
Cited by 2,450
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A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
the CARDIoGRAMplusC4D Consortium (2015) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 2,447
- Verified
Mammalian Telomeres End in a Large Duplex Loop
Griffith, J. D., Comeau, L., Rosenfield, S., Stansel, R. M., Bianchi, A., Moss, H., & de Lange, T. (1999) · Cell
Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry
Cited by 2,447
- Verified
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
Engelman, J. A. (2009) · Nature Reviews Cancer
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 2,445
- Verified
Adeno-associated virus vector as a platform for gene therapy delivery
Wang, D., Tai, P. W. L., & Gao, G. (2019) · Nature Reviews Drug Discovery
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 2,444
- Verified
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
de Brito, O. M., & Scorrano, L. (2008) · Nature
Mitochondrial Function and PathologyIon Channels and Receptors
Cited by 2,442
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