Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila

Brennecke, J., Aravin, A. A., Stark, A., Dus, M., Kellis, M., Sachidanandam, R., & Hannon, G. J. (2007) · Cell

Chromosomal and Genetic VariationsRNA Interference and Gene Delivery

Cited by 2,524

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.

Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., & Goldberg, A. L. (1994) · Cell

Ubiquitin and proteasome pathwaysProtease and Inhibitor Mechanisms

Cited by 2,524

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

Zimmermann, L., Stephens, A., Nam, S.-Z., Rau, D., Kübler, J., Lozajic, M., Gabler, F., Söding, J., Lupas, A. N., & Alva, V. (2018) · Journal of Molecular Biology

Genomics and Phylogenetic StudiesProtein Structure and Dynamics

Cited by 2,522

An Overview of Autophagy: Morphology, Mechanism, and Regulation

Parzych, K. R., & Klionsky, D. J. (2014) · Antioxidants & Redox Signaling

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,521

Requirement for Generation of H 2 O 2 for Platelet-Derived Growth Factor Signal Transduction

Sundaresan, M., Yu, Z.-X., Ferrans, V. J., Irani, K., & Finkel, T. (1995) · Science

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 2,520

Regulation of angiogenesis by hypoxia: role of the HIF system

Pugh, C. W., & Ratcliffe, P. J. (2003) · Nature Medicine

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 2,520

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

Liu, J., Xiao, Q., Xiao, J., Niu, C., Li, Y., Zhang, X., Zhou, Z., Shu, G., & Yin, G. (2022) · Signal Transduction and Targeted Therapy

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 2,519

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

Cani, P. D., Possemiers, S., Van de Wiele, T., Guiot, Y., Everard, A., Rottier, O., Geurts, L., Naslain, D., Neyrinck, A., Lambert, D. M., et al. (2009) · Gut

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 2,518

Raman Spectroscopy of Biological Tissues

Movasaghi, Z., Rehman, S., & Rehman, I. U. (2007) · Applied Spectroscopy Reviews

Spectroscopy Techniques in Biomedical and Chemical ResearchOptical Imaging and Spectroscopy Techniques

Cited by 2,518

The mutational landscape of lethal castration-resistant prostate cancer

Grasso, C. S., Wu, Y.-M., Robinson, D. R., Cao, X., Dhanasekaran, S. M., Khan, A. P., Quist, M. J., Jing, X., Lonigro, R. J., Brenner, J. C., et al. (2012) · Nature

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

Cited by 2,517

The impact of dietary fiber on gut microbiota in host health and disease

Makki, K., Deehan, E. C., Walter, J., & Bäckhed, F. (2018) · Cell Host & Microbe

Gut microbiota and healthFood composition and properties

Cited by 2,517

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

He, W.-T., Wan, H., Hu, L., Chen, P., Wang, X., Huang, Z., Yang, Z.-H., Zhong, C.-Q., & Han, J. (2015) · Cell Research

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,517

Photon yield of O2 evolution and chlorophyll fluorescence characteristics at 77 K among vascular plants of diverse origins

Bj�rkman, O., & Demmig, B. (1987) · Planta

Photosynthetic Processes and MechanismsPlant Water Relations and Carbon Dynamics

Cited by 2,514

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Sato, T., van Es, J. H., Snippert, H. J., Stange, D. E., Vries, R. G., van den Born, M., Barker, N., Shroyer, N. F., van de Wetering, M., & Clevers, H. (2011) · Nature

Wnt/β-catenin signaling in development and cancerDigestive system and related health

Cited by 2,510

Exploring protein native states and large‐scale conformational changes with a modified generalized born model

Onufriev, A., Bashford, D., & Case, D. A. (2004) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions

Cited by 2,507

Integration of biological networks and gene expression data using Cytoscape

Cline, M. S., Smoot, M., Cerami, E., Kuchinsky, A., Landys, N., Workman, C., Christmas, R., Avila-Campilo, I., Creech, M., Gross, B., et al. (2007) · Nature Protocols

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 2,507

Reconciling the chemistry and biology of reactive oxygen species

Winterbourn, C. C. (2008) · Nature Chemical Biology

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 2,504

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Carmeliet, P., Dor, Y., Herbert, J.-M., Fukumura, D., Brusselmans, K., Dewerchin, M., Neeman, M., Bono, F., Abramovitch, R., Maxwell, P., et al. (1998) · Nature

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 2,502

HSP90 and the chaperoning of cancer

Whitesell, L., & Lindquist, S. L. (2005) · Nature Reviews Cancer

Heat shock proteins researchCancer-related Molecular Pathways

Cited by 2,502

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Yachida, S., Jones, S., Bozic, I., Antal, T., Leary, R., Fu, B., Kamiyama, M., Hruban, R. H., Eshleman, J. R., Nowak, M. A., et al. (2010) · Nature

Cancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research

Cited by 2,502

Genomic DNA methylation: the mark and its mediators.

Klose, R. J., & Bird, A. P. (2006) · Trends in Biochemical Sciences

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,501

Progress and problems with the use of viral vectors for gene therapy

Thomas, C. E., Ehrhardt, A., & Kay, M. A. (2003) · Nature Reviews Genetics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 2,501

Protein kinase C and lipid signaling for sustained cellular responses

Nishizuka, Y. (1995) · The FASEB Journal

Protein Kinase Regulation and GTPase SignalingSphingolipid Metabolism and Signaling

Cited by 2,499

TEAD mediates YAP-dependent gene induction and growth control

Zhao, B., Ye, X., Yu, J., Li, L., Li, W., Li, S., Yu, J., Lin, J. D., Wang, C.-Y., Chinnaiyan, A. M., et al. (2008) · Genes & Development

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 2,498