Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

Rybak-Wolf, A., Stottmeister, C., Glažar, P., Jens, M., Pino, N., Giusti, S., Hanan, M., Behm, M., Bartok, O., Ashwal-Fluss, R., et al. (2015) · Molecular Cell

Circular RNAs in diseasesRNA Research and Splicing

Cited by 2,423

Role of cell shape in growth control

Folkman, J., & Moscona, A. (1978) · Nature

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 2,422

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Rogakou, E. P., Boon, C., Redon, C., & Bonner, W. M. (1999) · The Journal of Cell Biology

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 2,422

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

Galluzzi, L., Vitale, I., Abrams, J. M., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., Dawson, T. M., Dawson, V. L., El-Deiry, W. S., Fulda, S., et al. (2012) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 2,421

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

Dethlefsen, L., & Relman, D. A. (2011) · Proceedings of the National Academy of Sciences

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 2,421

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

Ishino, Y., Shinagawa, H., Makino, K., Amemura, M., & Nakata, A. (1987) · Journal of Bacteriology

Bacterial Genetics and BiotechnologyAlkaline Phosphatase Research Studies

Cited by 2,421

Protein modules and signalling networks

Pawson, T. (1995) · Nature

Protein Kinase Regulation and GTPase SignalingBioinformatics and Genomic Networks

Cited by 2,420

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

Margolin, A. A., Nemenman, I., Basso, K., Wiggins, C., Stolovitzky, G., Favera, R. D., & Califano, A. (2006) · BMC Bioinformatics

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 2,420

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Söderberg, O., Gullberg, M., Jarvius, M., Ridderstråle, K., Leuchowius, K.-J., Jarvius, J., Wester, K., Hydbring, P., Bahram, F., Larsson, L.-G., et al. (2006) · Nature Methods

Advanced biosensing and bioanalysis techniquesAdvanced Fluorescence Microscopy Techniques

Cited by 2,419

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

Sutton, R. B., Fasshauer, D., Jahn, R., & Brunger, A. T. (1998) · Nature

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 2,417

Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy

Rosenthal, P. B., & Henderson, R. (2003) · Journal of Molecular Biology

Advanced Electron Microscopy Techniques and ApplicationsEnzyme Structure and Function

Cited by 2,416

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

Haghverdi, L., Lun, A. T. L., Morgan, M. D., & Marioni, J. C. (2018) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 2,416

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

Roux, K. J., Kim, D. I., Raida, M., & Burke, B. (2012) · Journal of Cell Biology

Biotin and Related StudiesNuclear Structure and Function

Cited by 2,416

Rationally engineered Cas9 nucleases with improved specificity

Slaymaker, I. M., Gao, L., Zetsche, B., Scott, D. A., Yan, W. X., & Zhang, F. (2016) · Science

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,414

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., Mudie, L. J., Pleasance, E. D., Lau, K. W., Beare, D., Stebbings, L. A., et al. (2011) · Cell

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 2,414

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Villani, A.-C., Satija, R., Reynolds, G., Sarkizova, S., Shekhar, K., Fletcher, J., Griesbeck, M., Butler, A., Zheng, S., Lazo, S., et al. (2017) · Science

Single-cell and spatial transcriptomicsImmunotherapy and Immune Responses

Cited by 2,413

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Özcan, U., Yilmaz, E., Özcan, L., Furuhashi, M., Vaillancourt, E., Smith, R. O., Görgün, C. Z., & Hotamisligil, G. S. (2006) · Science

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 2,413

Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

Koenig, M., Hoffman, E. P., Bertelson, C. J., Monaco, A. P., Feener, C., & Kunkel, L. M. (1987) · Cell

Muscle Physiology and DisordersGenomics and Rare Diseases

Cited by 2,411

The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

Brown, A. J., Goldsworthy, S. M., Barnes, A. A., Eilert, M. M., Tcheang, L., Daniels, D., Muir, A. I., Wigglesworth, M. J., Kinghorn, I., Fraser, N. J., et al. (2003) · Journal of Biological Chemistry

Receptor Mechanisms and SignalingBiochemical Analysis and Sensing Techniques

Cited by 2,409

Intracellular Functions of N-Linked Glycans

Helenius, A., & Aebi, A. M. (2001) · Science

Glycosylation and Glycoproteins ResearchCellular transport and secretion

Cited by 2,405

Mitochondria and cancer

Wallace, D. C. (2012) · Nature Reviews Cancer

Mitochondrial Function and PathologyCancer, Hypoxia, and Metabolism

Cited by 2,404

HDAC6 is a microtubule-associated deacetylase

Hubbert, C., Guardiola, A., Shao, R., Kawaguchi, Y., Ito, A., Nixon, A., Yoshida, M., Wang, X.-F., & Yao, T.-P. (2002) · Nature

Microtubule and mitosis dynamicsHistone Deacetylase Inhibitors Research

Cited by 2,403

GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy

Parks, D. H., Chuvochina, M., Rinke, C., Mussig, A. J., Chaumeil, P.-A., & Hugenholtz, P. (2022) · Nucleic Acids Research

Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology

Cited by 2,402

Population-level analysis of gut microbiome variation

Falony, G., Joossens, M., Vieira-Silva, S., Wang, J., Darzi, Y., Faust, K., Kurilshikov, A., Bonder, M. J., Valles-Colomer, M., Vandeputte, D., et al. (2016) · Science

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 2,400