Most cited biochemistry, genetics and molecular biology papers
- Verified
Elucidation of a universal size-control mechanism in Drosophila and mammals
Dong, J., Feldmann, G., Huang, J., Wu, S., Zhang, N., Comerford, S. A., Gayyed, M. F., Anders, R. A., Maitra, A., & Pan, D. (2007) · Cell
Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics
Cited by 2,370
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Expression profiling reveals off-target gene regulation by RNAi
Jackson, A. L., Bartz, S. R., Schelter, J., Kobayashi, S. V., Burchard, J., Mao, M., Li, B., Cavet, G., & Linsley, P. S. (2003) · Nature Biotechnology
RNA Interference and Gene DeliveryCRISPR and Genetic Engineering
Cited by 2,370
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Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis
Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., et al. (2014) · Immunity
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 2,368
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Diabetes and Cancer
Giovannucci, E., Harlan, D. M., Archer, M. C., Bergenstal, R. M., Gapstur, S. M., Habel, L. A., Pollak, M., Regensteiner, J. G., & Yee, D. (2010) · Diabetes Care
Metabolism, Diabetes, and CancerCancer Risks and Factors
Cited by 2,366
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Nonviral vectors for gene delivery
Mintzer, M. A., & Simanek, E. E. (2009) · Chemical Reviews
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 2,366
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Transforming Growth Factor-β Signaling in Immunity and Cancer
Batlle, E., & Massagué, J. (2019) · Immunity
TGF-β signaling in diseasesT-cell and B-cell Immunology
Cited by 2,366
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Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
Németh, K., Leelahavanichkul, A., Yuen, P. S. T., Mayer, B., Parmelee, A., Doi, K., Robey, P. G., Leelahavanichkul, K., Koller, B. H., Brown, J. M., et al. (2009) · Nature Medicine
Mesenchymal stem cell researchSepsis Diagnosis and Treatment
Cited by 2,364
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Polyploid incidence and evolution
Otto, S. P., & Whitton, J. (2000) · Annual Review of Genetics
Chromosomal and Genetic VariationsPlant Taxonomy and Phylogenetics
Cited by 2,363
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Cellular senescence in aging and age-related disease: from mechanisms to therapy
Childs, B. G., Durik, M., Baker, D. J., & van Deursen, J. M. (2015) · Nature Medicine
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 2,363
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Current knowledge on exosome biogenesis and release
Hessvik, N. P., & Llorente, A. (2018) · Cellular and Molecular Life Sciences
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 2,362
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Commensal Host-Bacterial Relationships in the Gut
Hooper, L. V., & Gordon, J. I. (2001) · Science
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 2,362
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Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
Hsiang, Y. H., Hertzberg, R., Hecht, S., & Liu, L. F. (1985) · Journal of Biological Chemistry
Cancer therapeutics and mechanismsBioactive Compounds and Antitumor Agents
Cited by 2,362
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The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
Dethlefsen, L., Huse, S., Sogin, M. L., & Relman, D. A. (2008) · PLoS Biology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 2,361
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NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand data
Reynisson, B., Alvarez, B., Paul, S., Peters, B., & Nielsen, M. (2020) · Nucleic Acids Research
vaccines and immunoinformatics approachesImmunotherapy and Immune Responses
Cited by 2,361
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Smart-seq2 for sensitive full-length transcriptome profiling in single cells
Picelli, S., Björklund, Å. K., Faridani, O. R., Sagasser, S., Winberg, G., & Sandberg, R. (2013) · Nature Methods
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 2,358
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Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: A proof-of-concept exploratory study
Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., et al. (2019) · Nature Medicine
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 2,357
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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
Thomas, K. R., & Capecchi, M. R. (1987) · Cell
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 2,355
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An integrated map of structural variation in 2,504 human genomes
Sudmant, P. H., Rausch, T., Gardner, E. J., Handsaker, R. E., Abyzov, A., Huddleston, J., Zhang, Y., Ye, K., Jun, G., Hsi-Yang Fritz, M., et al. (2015) · Nature
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 2,354
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GMAP: A genomic mapping and alignment program for mRNA and EST sequences
Wu, T. D., & Watanabe, C. K. (2005) · Bioinformatics
Genomics and Phylogenetic StudiesRNA Research and Splicing
Cited by 2,354
- Verified
Pyroptosis: Mechanisms and Diseases
Yu, P., Zhang, X., Liu, N., Tang, L., Peng, C., & Chen, X. (2021) · Signal Transduction and Targeted Therapy
Inflammasome and immune disordersFerroptosis and cancer prognosis
Cited by 2,353
- Verified
Detection of nonneutral substitution rates on mammalian phylogenies
Pollard, K. S., Hubisz, M. J., Rosenbloom, K. R., & Siepel, A. (2010) · Genome Research
Genomics and Phylogenetic StudiesEvolution and Genetic Dynamics
Cited by 2,353
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Mendelian Randomization as an Approach to Assess Causality Using Observational Data
Sekula, P., Del Greco M, F., Pattaro, C., & Köttgen, A. (2016) · Journal of the American Society of Nephrology
Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques
Cited by 2,351
- Verified
Integrating cell-signalling pathways with NF-κB and IKK function
Perkins, N. D. (2007) · Nature Reviews Molecular Cell Biology
NF-κB Signaling PathwaysSignaling Pathways in Disease
Cited by 2,350
- Verified
Tracking the Evolution of Non–Small-Cell Lung Cancer
Jamal-Hanjani, M., Wilson, G. A., McGranahan, N., Birkbak, N. J., Watkins, T. B. K., Veeriah, S., Shafi, S., Johnson, D. H., Mitter, R., Rosenthal, R., et al. (2017) · New England Journal of Medicine
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 2,349
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