Nut Consumption and Blood Lipid Levels: A Pooled Analysis of 25 Intervention Trials

Sabaté, Joan

doi:10.1001/archinternmed.2010.79

Cited by 422Nuts composition and effectsNutritional Studies and DietLipoproteins and Cardiovascular Health

Nut Consumption and Blood Lipid Levels: A Pooled Analysis of 25 Intervention Trials

Sabaté, Joan·2010·Archives of Internal Medicine

DOI 10.1001/archinternmed.2010.79

Open this paper in CoChat — free account

Abstract

BACKGROUND: Epidemiological studies have consistently associated nut consumption with reduced risk for coronary heart disease. Subsequently, many dietary intervention trials investigated the effects of nut consumption on blood lipid levels. The objectives of this study were to estimate the effects of nut consumption on blood lipid levels and to examine whether different factors modify the effects. METHODS: We pooled individual primary data from 25 nut consumption trials conducted in 7 countries among 583 men and women with normolipidemia and hypercholesterolemia who were not taking lipid-lowering medications. In a pooled analysis, we used mixed linear models to assess the effects of nut consumption and the potential interactions. RESULTS: With a mean daily consumption of 67 g of nuts, the following estimated mean reductions were achieved: total cholesterol concentration (10.9 mg/dL [5.1% change]), low-density lipoprotein cholesterol concentration (LDL-C) (10.2 mg/dL [7.4% change]), ratio of LDL-C to high-density lipoprotein cholesterol concentration (HDL-C) (0.22 [8.3% change]), and ratio of total cholesterol concentration to HDL-C (0.24 [5.6% change]) (P < .001 for all) (to convert all cholesterol concentrations to millimoles per liter, multiply by 0.0259). Triglyceride levels were reduced by 20.6 mg/dL (10.2%) in subjects with blood triglyceride levels of at least 150 mg/dL (P < .05) but not in those with lower levels (to convert triglyceride level to millimoles per liter, multiply by 0.0113). The effects of nut consumption were dose related, and different types of nuts had similar effects on blood lipid levels. The effects of nut consumption were significantly modified by LDL-C, body mass index, and diet type: the lipid-lowering effects of nut consumption were greatest among subjects with high baseline LDL-C and with low body mass index and among those consuming Western diets. CONCLUSION: Nut consumption improves blood lipid levels in a dose-related manner, particularly among subjects with higher LDL-C or with lower BMI.

Integrity signals

Registry

Crossref · 10.1001/archinternmed.2010.79

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Adults with elevated cholesterol exhibit larger cholesterol reductions in response to targeted dietary intervention.
“Evidence supports that adults with elevated cholesterol exhibit larger cholesterol reductions in response to targeted dietary intervention [51,52].”
From Dietary Polyunsaturated to Saturated Fatty Acid Ratio as an Indicator for LDL Cholesterol Response: A Systematic Review and Meta-Analysis of Randomized Clinical Trials (2025) · cites this paper as [52]
Systematic reviews and meta-analyses of randomized controlled trials have shown reductions in LDL-C of 7% for nuts at a median dose of 67 g/d.
“Systematic reviews and meta-analyses of randomized controlled trials have shown reductions in LDL-C of 7% for nuts at a median dose of 67 g/d, 33”
From Portfolio Dietary Pattern and Cardiovascular Disease: A Systematic Review and Meta-analysis of Controlled Trials (2018) · cites this paper as [33]
Systematic reviews and meta-analyses of randomized controlled trials have shown beneficial effects of nuts on non-HDL-C, apoB, TC, and TG.
“Systematic reviews and meta-analyses of randomized controlled trials have shown beneficial effects of plant sterols, 38,39 viscous fibres, 37,40,41 plant proteins, 34 and nuts 33,42,43 on the established alternate lipid targets, non-HDL-C and apoB, and other blood lipids including TC and TG.”
From Portfolio Dietary Pattern and Cardiovascular Disease: A Systematic Review and Meta-analysis of Controlled Trials (2018) · cites this paper as [33]
In clinical trials, nuts improve serum lipids.
“In clinical trials nuts improve serum lipids (209) (210,211).”
From Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System (2015) · cites this paper as [210]

Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Grundy, S. M., Becker, D. M., Clark, L. T., Cooper, R., Denke, M. A., Howard, J. L., Hunninghake, D. B., Illingworth, D. R., Luepker, R. V., McBride, P. E., et al. (2002) · Civil War Book Review · Cited by 12,198 · see citing works
AHA Dietary Guidelines: Revision 2000: A Statement for Healthcare Professionals From the Nutrition Committee of the American Heart Association
Krauss, R. M., Eckel, R. H., Howard, B., Appel, L. J., Daniels, S. R., Deckelbaum, R. J., Erdman, J. W., Kris-Etherton, P., Goldberg, I. J., Kotchen, T. A., et al. (2000) · Circulation · doi:10.1161/01.cir.102.18.2284 · Cited by 1,458 · see citing works
Dietary Antioxidant Vitamins and Death from Coronary Heart Disease in Postmenopausal Women
Kushi, L. H., Folsom, A. R., Prineas, R. J., Mink, P. J., Wu, Y. G., & Bostick, R. M. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605023341803 · Cited by 959 · see citing works
A Possible Protective Effect of Nut Consumption on Risk of Coronary Heart Disease
Fraser, G. E. (1992) · Archives of Internal Medicine · doi:10.1001/archinte.152.7.1416 · Cited by 730 · see citing works
Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study
Hu, F. B., Stampfer, M. J., Manson, J. E., Rimm, E. B., Colditz, G. A., Rosner, B. A., Speizer, F. E., Hennekens, C. H., & Willett, W. C. (1998) · BMJ · doi:10.1136/bmj.317.7169.1341 · Cited by 597 · see citing works
High–monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations
Kris‐Etherton, P. M., Pearson, T. A., Wan, Y., Hargrove, R. L., Moriarty, K., Fishell, V. K., & Etherton, T. D. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.6.1009 · Cited by 591 · see citing works
Nut and peanut butter consumption and risk of type 2 diabetes in women
Jiang, R. (2002) · JAMA · doi:10.1001/jama.288.20.2554 · Cited by 489 · see citing works
A Walnut Diet Improves Endothelial Function in Hypercholesterolemic Subjects
Ros, E., Núñez, I., Pérez-Heras, A., Serra, M., Gilabert, R., Casals, E., & Deulofeu, R. (2004) · Circulation · doi:10.1161/01.cir.0000124477.91474.ff · Cited by 472 · see citing works
Effect of a Mediterranean Diet Supplemented With Nuts on Metabolic Syndrome Status: One-Year Results of the PREDIMED Randomized Trial
Salas-Salvadó, J., Fernández-Ballart, J., Ros, E., Martínez-González, M.-A., Fitó, M., Estruch, R., Corella, D., Fiol, M., Gómez-Gracia, E., Arós, F., et al. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.22.2449 · Cited by 463 · see citing works
Pleiotropic Effects of Statins: Benefit Beyond Cholesterol Reduction?
Robinson, J. G., Smith, B., Maheshwari, N., & Schrott, H. G. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.05.085 · Cited by 407 · see citing works
Effects of Walnuts on Serum Lipid Levels and Blood Pressure in Normal Men
Sabaté, J., Fraser, G. E., Burke, K. I., Knutsen, S. F., Bennett, H., & Lindsted, K. D. (1993) · New England Journal of Medicine · doi:10.1056/nejm199303043280902 · Cited by 397 · see citing works
Nut consumption and decreased risk of sudden cardiac death in the Physicians’ Health Study
Albert, C. M., Gaziano, J. M., Willett, W. C., & Manson, J. E. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.12.1382 · Cited by 396 · see citing works
Dose Response of Almonds on Coronary Heart Disease Risk Factors: Blood Lipids, Oxidized Low-Density Lipoproteins, Lipoprotein(a), Homocysteine, and Pulmonary Nitric Oxide
Jenkins, D. J. A., Kendall, C. W. C., Marchie, A., Parker, T. L., Connelly, P. W., Qian, W., Haight, J. S. J., Faulkner, D. A., Vidgen, E., Lapsley, K. G., et al. (2002) · Circulation · doi:10.1161/01.cir.0000028421.91733.20 · Cited by 378 · see citing works
Nuts and their bioactive constituents: effects on serum lipids and other factors that affect disease risk
Kris-Etherton, P. M., Yu-Poth, S., Sabaté, J., Ratcliffe, H. E., Zhao, G., & Etherton, T. D. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.3.504s · Cited by 339 · see citing works
Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins—the Jerusalem Nutrition Study: high MUFAs vs high PUFAs
Berry, E., Eisenberg, S., Haratz, D., Friedlander, Y., Norman, Y., Kaufmann, N., & Stein, Y. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.4.899 · Cited by 334 · see citing works
Effects of walnut consumption on blood lipids and other cardiovascular risk factors: a meta-analysis and systematic review
Banel, D. K., & Hu, F. B. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27457 · Cited by 310 · see citing works
Substituting Walnuts for Monounsaturated Fat Improves the Serum Lipid Profile of Hypercholesterolemic Men and Women
Zambón, D., Sabaté, J., Muñoz, S., Campero, B., Casals, E., Merlos, M., Laguna, J. C., & Ros, E. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-132-7-200004040-00005 · Cited by 309 · see citing works
Fatty acid composition of nuts – implications for cardiovascular health
Ros, E., & Mataix, J. (2006) · British Journal Of Nutrition · doi:10.1017/bjn20061861 · Cited by 306 · see citing works
Including Walnuts in a Low-Fat/Modified-Fat Diet Improves HDL Cholesterol-to-Total Cholesterol Ratios in Patients With Type 2 Diabetes
Tapsell, L. C., Gillen, L. J., Patch, C. S., Batterham, M. J., Owen, A. J., Baré, M., & Kennedy, M. A. (2004) · Diabetes Care · doi:10.2337/diacare.27.12.2777 · Cited by 280 · see citing works
Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol
Abbey, M., Noakes, M., Belling, G. B., & Nestel, P. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/59.5.995 · Cited by 251 · see citing works
Effect of diets enriched in almonds on insulin action and serum lipids in adults with normal glucose tolerance or type 2 diabetes,,
Lovejoy, J. C., Most, M. M., LeFevre, M. L., Greenway, F. L., & Rood, J. C. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.5.1000 · Cited by 220 · see citing works
Nuts: source of energy and macronutrients
Brufau, G., Boatella, J., & Rafecas, M. (2006) · British Journal Of Nutrition · doi:10.1017/bjn20061860 · Cited by 213 · see citing works
A Monounsaturated Fatty Acid–Rich Pecan-Enriched Diet Favorably Alters the Serum Lipid Profile of Healthy Men and Women
Rajaram, S., Myint, T., Sabaté, J., Burke, K. I., & Connell, B. C. (2001) · Journal of Nutrition · doi:10.1093/jn/131.9.2275 · Cited by 208 · see citing works
Nut Consumption and Weight Gain in a Mediterranean Cohort: The SUN Study
Bes‐Rastrollo, M., Sabaté, J., Gómez‐Gracia, E., Alonso, Á., Martínez, J. A., & Martínez‐González, M. Á. (2007) · Obesity · doi:10.1038/oby.2007.507 · Cited by 201 · see citing works
Almonds and Almond Oil Have Similar Effects on Plasma Lipids and LDL Oxidation in Healthy Men and Women
Hyson, D. A., Schneeman, B. O., & Davis, P. A. (2002) · Journal of Nutrition · doi:10.1093/jn/132.4.703 · Cited by 201 · see citing works
Nuts and Plasma Lipids: An Almond-Based Diet Lowers LDL-C while Preserving HDL-C
Spiller, G. A., Jenkins, D. J. A., Bosello, O., Gates, J. E., Cragen, L. N., & Bruce, B. (1998) · Journal of the American College of Nutrition · doi:10.1080/07315724.1998.10718761 · Cited by 200 · see citing works
Low fat‐monounsaturated rich diets containing high‐oleic peanuts improve serum lipoprotein profiles
O’Byrne, D., Knauft, D. A., & Shireman, R. B. (1997) · Lipids · doi:10.1007/s11745-997-0088-y · Cited by 199 · see citing works
Other relevant components of nuts: phytosterols, folate and minerals
Segura, R., Javierre, C. F., Lizarraga, M. A., & Ros, E. (2006) · British Journal Of Nutrition · doi:10.1017/bjn20061862 · Cited by 195 · see citing works
Nuts and coronary heart disease: an epidemiological perspective
Kelly, J. H., & Sabaté, J. (2006) · British Journal of Nutrition · doi:10.1017/bjn20061865 · Cited by 193 · see citing works
Self-citation
Serum lipid response to the graduated enrichment of a Step I diet with almonds: a randomized feeding trial
Sabaté, J., Haddad, E. H., Tanzman, J. S., Jambazian, P., & Rajaram, S. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.6.1379 · Cited by 184 · see citing works
Introducing a new component of the metabolic syndrome: low cholesterol absorption
Simonen, P. P., Gylling, H., Howard, A. N., & Miettinen, T. A. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.1.82 · Cited by 183 · see citing works
Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia
Almario, R. U., Vonghavaravat, V., Wong, R., & Kasim-Karakas, S. E. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.1.72 · Cited by 180 · see citing works
Macadamia Nut Consumption Lowers Plasma Total and LDL Cholesterol Levels in Hypercholesterolemic Men
Garg, M. L., Blake, R. J., & Wills, R. B. H. (2003) · Journal of Nutrition · doi:10.1093/jn/133.4.1060 · Cited by 175 · see citing works
Serum Lipid Effects of a High–Monounsaturated Fat Diet Based on Macadamia Nuts
Curb, J. D., Wergowske, G. L., Dobbs, J. C., Abbott, R. D., & Huang, B. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.8.1154 · Cited by 172 · see citing works
Peanut Consumption Improves Indices of Cardiovascular Disease Risk in Healthy Adults
Alper, C. M., & Mattes, R. D. (2003) · Journal of the American College of Nutrition · doi:10.1080/07315724.2003.10719286 · Cited by 143 · see citing works
Effect of Pistachio Nuts on Serum Lipid Levels in Patients with Moderate Hypercholesterolemia
Edwards, K., Kwaw, I., Matud, J. L., & Kurtz, I. (1999) · Journal of the American College of Nutrition · doi:10.1080/07315724.1999.10718856 · Cited by 143 · see citing works
Nuts, body weight and insulin resistance
Rajaram, S., & Sabaté, J. (2006) · British Journal Of Nutrition · doi:10.1017/bjn20061867 · Cited by 141 · see citing works
Pecans Lower Low Density Lipoprotein Cholesterol in People with Normal Lipid Levels
MORGAN, W. A., & CLAYSHULTE, B. J. (2000) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(00)00097-3 · Cited by 137 · see citing works
Pistachio Nut Consumption and Serum Lipid Levels
Sheridan, M., Cooper, J. N., Erario, M., & Cheifetz, C. E. (2007) · Journal of the American College of Nutrition · doi:10.1080/07315724.2007.10719595 · Cited by 135 · see citing works
Effects of a high walnut and high cashew nut diet on selected markers of the metabolic syndrome: a controlled feeding trial
Mukuddem-Petersen, J., Stonehouse (Oosthuizen), W., Jerling, J. C., Hanekom, S. M., & White, Z. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507682944 · Cited by 131 · see citing works
Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins—the Jerusalem Nutrition Study. II Monounsaturated fatty acids vs carbohydrates
Berry, E., Eisenberg, S., Friedlander, Y., Harats, D., Kaufmann, N., Norman, Y., & Stein, Y. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/56.2.394 · Cited by 129 · see citing works
Serum lipid profiles in Japanese women and men during consumption of walnuts
Iwamoto, M., Imaizumi, K., Sato, M., Hirooka, Y., Sakai, K., Takeshita, A., & Kono, M. (2002) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601400 · Cited by 120 · see citing works
A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects
Chisholm, A. W., Mann, J. I., Skeaff, M., Frampton, C. M. A., Sutherland, W. H. F., Duncan, A. W., & Tiszavari, S. (1998) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600507 · Cited by 114 · see citing works
Individual variability in cardiovascular disease risk factor responses to low-fat and low-saturated-fat diets in men: body mass index, adiposity, and insulin resistance predict changes in LDL cholesterol
LeFevre, M. L., Champagne, C. M., Tulley, R. T., Rood, J. C., & Most, M. M. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.957 · Cited by 104 · see citing works
Effects of Insulin Resistance and Obesity on Lipoproteins and Sensitivity to Egg Feeding
Knopp, R. H., Retzlaff, B. M., Fish, B. E., Walden, C. E., Wallick, S., Anderson, M., Aikawa, K., & Kahn, S. E. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000082461.77557.c7 · Cited by 100 · see citing works
Hazelnut supplementation enhances plasma antioxidant potential and lowers plasma cholesterol levels
Durak, İ., Köksal, İ., Kaçmaz, M., Büyükkoçak, S., Çimen, B., & Öztürk, S. (1999) · Clinica Chimica Acta · doi:10.1016/s0009-8981(99)00066-2 · Cited by 95 · see citing works
Nuts: nutrition and health outcomes
Sabaté, J., Ros, E., & Salas‐Salvadó, J. (2006) · British Journal Of Nutrition · doi:10.1017/bjn20061857 · Cited by 90 · see citing works
Effects of a macadamia nut enriched diet on serum lipids and lipoproteins compared to a low fat diet
Colquhoun, D., Humphries, J., Moores, D., & Somerset, S. M. (1996) · Food Australia · Cited by 54 · see citing works
Nuts: a new protective food against coronary heart disease
Sabat, J., & Fraser, G. E. (1994) · Current Opinion in Lipidology · doi:10.1097/00041433-199402000-00003 · Cited by 49 · see citing works
Nut consumption and change in weight: the weight of the evidence
Sabaté, J. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507791869 · Cited by 9 · see citing works

Flagged first, then by citations

1 of the 52 references couldn’t be matched to a known paper.

Sorted by citations

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association
Benjamin, E. J., Blaha, M. J., Chiuve, S. E., Cushman, M., Das, S. R., Deo, R., de Ferranti, S. D., Floyd, J., Fornage, M., Gillespie, C., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000485 · Cited by 12,591 · see citing works
Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems
Willett, W., Rockström, J., Loken, B., Springmann, M., Lang, T., Vermeulen, S., Garnett, T., Tilman, D., DeClerck, F., Wood, A., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(18)31788-4 · Cited by 10,880 · see citing works
Heart disease and stroke statistics-2018 update: a report from the american heart association
Benjamin, E. J., Virani, S. S., Callaway, C. W., Chamberlain, A. M., Chang, A. R., Cheng, S., Chiuve, S. E., Cushman, M., Delling, F. N., Deo, R., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000558 · Cited by 7,146 · see citing works
Heart Disease and Stroke Statistics—2012 Update: A Report From the American Heart Association
Writing Group Members, Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., et al. (2012) · Circulation · doi:10.1161/cir.0b013e31823ac046 · Cited by 7,333 · see citing works
Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., Das, S. R., de Ferranti, S., Després, J.-P., Fullerton, H. J., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000350 · Cited by 6,596 · see citing works
Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., de Ferranti, S., Després, J.-P., Fullerton, H. J., Howard, V. J., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000152 · Cited by 5,797 · see citing works
Heart Disease and Stroke Statistics—2014 Update
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Blaha, M. J., Dai, S., Ford, E. S., Fox, C. S., Franco, S., et al. (2013) · Circulation · doi:10.1161/01.cir.0000441139.02102.80 · Cited by 5,207 · see citing works
Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31828124ad · Cited by 5,292 · see citing works
Health Benefits of Nut Consumption
Ros, E. (2010) · Nutrients · doi:10.3390/nu2070652 · Cited by 773 · see citing works
Dyslipidemia
Kopin, L., & Lowenstein, C. J. (2017) · Annals of Internal Medicine · doi:10.7326/aitc201712050 · Cited by 589 · see citing works
Diabetic dyslipidemia
Li-ya, W., & Parhofer, K. G. (2014) · Metabolism · doi:10.1016/j.metabol.2014.08.010 · Cited by 523 · see citing works
Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke, and diabetes: a systematic review and meta-analysis
Afshin, A., Micha, R., Khatibzadeh, S., & Mozaffarian, D. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.076901 · Cited by 509 · see citing works
Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System
Anand, S. S., Hawkes, C., de Souza, R. J., Mente, A., Dehghan, M., Nugent, R., Zulyniak, M. A., Weis, T., Bernstein, A. M., Krauss, R. M., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.07.050 · Cited by 507 · see citing works
“a) CVD Risk Factors: In clinical trials nuts improve serum lipids (209) (210,211).”
Background
Tree nut phytochemicals: composition, antioxidant capacity, bioactivity, impact factors. A systematic review of almonds, Brazils, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts
Bolling, B. W., Chen, C.-Y. O., McKay, D. L., & Blumberg, J. B. (2011) · Nutrition Research Reviews · doi:10.1017/s095442241100014x · Cited by 455 · see citing works
Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation
Pérez‐Martínez, P., Mikhailidis, D. P., Athyros, V. G., Bulló, M., Couture, P., Covas, M. I., de Koning, L., Delgado‐Lista, J., Díaz‐López, A., Drevon, C. A., et al. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nux014 · Cited by 410 · see citing works
Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies
Aune, D., Keum, N., Giovannucci, E. L., Fadnes, L. T., Boffetta, P., Greenwood, D. C., Tonstad, S., VATTEN, L. J., Ríboli, E., & Norat, T. (2016) · BMC Medicine · doi:10.1186/s12916-016-0730-3 · Cited by 402 · see citing works
The 2015 Dutch food-based dietary guidelines
Kromhout, D., Spaaij, C. J. K., de Goede, J., & Weggemans, R. M. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.52 · Cited by 400 · see citing works
Ellagitannins, ellagic acid and vascular health
Larrosa, M., García‐Conesa, M., Espı́n, J. C., & Tomás-Barberán, F. A. (2010) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2010.09.005 · Cited by 378 · see citing works
Association of Nut Consumption with Total and Cause-Specific Mortality
Bao, Y., Han, J., Hu, F. B., Giovannucci, E. L., Stampfer, M. J., Willett, W. C., & Fuchs, C. S. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1307352 · Cited by 362 · see citing works
An International Atherosclerosis Society Position Paper: Global recommendations for the management of dyslipidemia
Grundy, S. M. (2013) · Journal of clinical lipidology · doi:10.1016/j.jacl.2013.10.001 · Cited by 349 · see citing works
Effects of tree nuts on blood lipids, apolipoproteins, and blood pressure: systematic review, meta-analysis, and dose-response of 61 controlled intervention trials
Del Gobbo, L. C., Falk, M. C., Feldman, R., Lewis, K., & Mozaffarian, D. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.110965 · Cited by 335 · see citing works
An International Atherosclerosis Society Position Paper: Global recommendations for the management of dyslipidemia-Full report
Grundy, S. M., Arai, H., Barter, P. J., Bersot, T. P., Betteridge, D. J., Carmena, R., Cuevas, A. M., Davidson, M. H., Genest, J. J., Kesäniemi, Y. A., et al. (2013) · Journal of clinical lipidology · doi:10.1016/j.jacl.2013.12.005 · Cited by 328 · see citing works
Beyond meatless, the health effects of vegan diets: findings from the adventist cohorts
Le, L., & Sabaté, J. (2014) · Nutrients · doi:10.3390/nu6062131 · Cited by 319 · see citing works
Vegetarian diets, low-meat diets and health: a review
McEvoy, C. T., Temple, N., & Woodside, J. V. (2012) · Public Health Nutrition · doi:10.1017/s1368980012000936 · Cited by 316 · see citing works
Polyphenol-Rich Foods in the Mediterranean Diet are Associated with Better Cognitive Function in Elderly Subjects at High Cardiovascular Risk
Valls-Pedret, C., Lamuela-Raventós, R. M., Medina-Remón, A., Quintana, M., Corella, D., Pintó, X., Martínez-González, M. Á., Estruch, R., & Ros, E. (2012) · Journal of Alzheimer's Disease · doi:10.3233/jad-2012-111799 · Cited by 309 · see citing works
A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality
Wadhera, R. K., Steen, D. L., Khan, I., Giugliano, R. P., & Foody, J. M. (2016) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.11.010 · Cited by 306 · see citing works
Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022
Okamura, T., Tsukamoto, K., Arai, H., Fujioka, Y., Ishigaki, Y., Koba, S., Ohmura, H., Shoji, T., Yokote, K., Yoshida, H., et al. (2023) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2022 · Cited by 317 · see citing works
A healthy approach to dietary fats: understanding the science and taking action to reduce consumer confusion
Liu, A. G., Ford, N. A., Hu, F. B., Zelman, K. M., Mozaffarian, D., & Kris‐Etherton, P. M. (2017) · Nutrition Journal · doi:10.1186/s12937-017-0271-4 · Cited by 287 · see citing works
Fatty acids in cardiovascular health and disease: A comprehensive update
Baum, S. J., Kris‐Etherton, P. M., Willett, W. C., Lichtenstein, A. H., Rudel, L. L., Maki, K. C., Whelan, J., Ramsden, C. E., & Block, R. (2012) · Journal of clinical lipidology · doi:10.1016/j.jacl.2012.04.077 · Cited by 279 · see citing works
Polyphenol intake from a Mediterranean diet decreases inflammatory biomarkers related to atherosclerosis: a substudy of the PREDIMED trial
Medina‐Remón, A., Casas, R. M., Tresserra‐Rimbau, A., Ros, E., Martínez‐González, M. Á., Fitó, M., Corella, D., Salas‐Salvadó, J., Lamuela-Raventós, R. M., Estruch, R., et al. (2016) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12986 · Cited by 272 · see citing works
Evidence-based European recommendations for the dietary management of diabetes
The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD), Aas, A.-M., Axelsen, M., Churuangsuk, C., Hermansen, K., Kendall, C. W. C., Kahleova, H., Khan, T., Lean, M. E. J., Mann, J. I., et al. (2023) · Diabetologia · doi:10.1007/s00125-023-05894-8 · Cited by 262 · see citing works
Nut consumption and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis
Luo, C., Zhang, Y., Ding, Y., Shan, Z., Chen, S., Yu, M., Hu, F. B., & Liu, L. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.076109 · Cited by 246 · see citing works
Portfolio Dietary Pattern and Cardiovascular Disease: A Systematic Review and Meta-analysis of Controlled Trials
Chiavaroli, L., Nishi, S. K., Khan, T. A., Braunstein, C. R., Glenn, A. J., Mejia, S. B., Rahelić, D., Kahleová, H., Salas-Salvadó, J., Jenkins, D. J. A., et al. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.05.004 · Cited by 226 · see citing works
Nutritional Recommendations for Cardiovascular Disease Prevention
Eilat-Adar, S., Sinai, T., Yosefy, C., & Henkin, Y. (2013) · Nutrients · doi:10.3390/nu5093646 · Cited by 236 · see citing works
Nut consumption on all-cause, cardiovascular, and cancer mortality risk: a systematic review and meta-analysis of epidemiologic studies
Grosso, G., Yang, J., Marventano, S., Micek, A., Galvano, F., & Kales, S. N. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.099515 · Cited by 225 · see citing works
Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia: A Randomized Controlled Trial
Jenkins, D. J. A., Jones, P. J. H., Lamarche, B., Kendall, C. W. C., Faulkner, D., Cermakova, L., Gigleux, I., Ramprasath, V., de Souza, R., Ireland, C., et al. (2011) · JAMA · doi:10.1001/jama.2011.1202 · Cited by 218 · see citing works
Dietary macronutrients and food consumption as determinants of long-term weight change in adult populations: a systematic literature review
Fogelholm, M., Anderssen, S. A., Gunnarsdóttir, I., & Lahti‐Koski, M. (2012) · Food & Nutrition Research · doi:10.3402/fnr.v56i0.19103 · Cited by 214 · see citing works
Plant Foods, Antioxidant Biomarkers, and the Risk of Cardiovascular Disease, Cancer, and Mortality: A Review of the Evidence
Aune, D. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz042 · Cited by 215 · see citing works
Nutrition Therapy
Sievenpiper, J. L., Chan, C. B., Dworatzek, P. D., Freeze, C., & Williams, S. L. (2018) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2017.10.009 · Cited by 200 · see citing works
Nut intake and adiposity: meta-analysis of clinical trials
Flores-Mateo, G., Rojas-Rueda, D., Basora, J., Ros, E., & Salas-Salvadó, J. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.031484 · Cited by 185 · see citing works
Nut Consumption and Risk of Cardiovascular Disease
Guasch‐Ferré, M., Liu, X., Malik, V., Sun, Q., Willett, W. C., Manson, J. E., Rexrode, K. M., Li, Y., Hu, F. B., & Bhupathiraju, S. N. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.09.035 · Cited by 177 · see citing works
Pecan nuts: A review of reported bioactivities and health effects
Atanasov, A. G., Sabharanjak, S. M., Zengin, G., Mollica, A., Szostak, A., Simirgiotis, M. J., Huminiecki, Ł., Horbańczuk, O. K., Nabavi, S. M., & Mocan, A. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.10.019 · Cited by 177 · see citing works
Dietary fats and cardiovascular disease: Putting together the pieces of a complicated puzzle
Michas, G., Micha, R., & Zampelas, A. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.03.013 · Cited by 173 · see citing works
Red meat, diseases, and healthy alternatives: A critical review
Ekmekcioglu, C., Wallner, P., Kundi, M., Weisz, U., Haas, W., & Hutter, H.-P. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1158148 · Cited by 173 · see citing works
Effect of Tree Nuts on Glycemic Control in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Dietary Trials
Viguiliouk, E., Kendall, C. W. C., Mejía, S. B., Cozma, A. I., Ha, V., Mirrahimi, A., Jayalath, V. H., Augustin, L. S. A., Chiavaroli, L., Leiter, L. A., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103376 · Cited by 171 · see citing works
Nut consumption and incidence of cardiovascular diseases and cardiovascular disease mortality: a meta-analysis of prospective cohort studies
Becerra‐Tomás, N., Paz‐Graniel, I., Kendall, C. W. C., Kahleová, H., Rahelić, D., Sievenpiper, J. L., & Salas‐Salvadó, J. (2019) · Nutrition Reviews · doi:10.1093/nutrit/nuz042 · Cited by 170 · see citing works
Walnut Consumption Is Associated with Lower Risk of Type 2 Diabetes in Women
Pan, A., Sun, Q., Manson, J. E., Willett, W. C., & Hu, F. B. (2013) · Journal of Nutrition · doi:10.3945/jn.112.172171 · Cited by 167 · see citing works
Crossover study of diets enriched with virgin olive oil, walnuts or almonds. Effects on lipids and other cardiovascular risk markers
Damasceno, N. R. T., Pérez-Heras, A., Serra, M., Cofán, M., Sala‐Vila, A., Salas‐Salvadó, J., & Ros, E. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.12.006 · Cited by 165 · see citing works
Trending Cardiovascular Nutrition Controversies
Freeman, A. M., Morris, P. B., Barnard, N. D., Esselstyn, C. B., Ros, E., Agatston, A. S., Devries, S. R., O’Keefe, J. H., Miller, M. J., Ornish, D. M., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.10.086 · Cited by 166 · see citing works
Mediterranean diet supplemented with nuts reduces waist circumference and shifts lipoprotein subfractions to a less atherogenic pattern in subjects at high cardiovascular risk
Damasceno, N. R. T., Sala‐Vila, A., Cofán, M., Pérez-Heras, A., Fitó, M., Ruíz-Gutiérrez, V., Martínez‐González, M. Á., Corella, D., Arós, F., Estruch, R., et al. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.08.014 · Cited by 164 · see citing works
Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial
Guasch‐Ferré, M., Bulló, M., Martínez‐González, M. Á., Ros, E., Corella, D., Estruch, R., Fitó, M., Arós, F., Wärnberǵ, J., Fiol, M., et al. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-164 · Cited by 159 · see citing works
Benefits of Nut Consumption on Insulin Resistance and Cardiovascular Risk Factors: Multiple Potential Mechanisms of Actions
Kim, Y., Keogh, J. B., & Clifton, P. M. (2017) · Nutrients · doi:10.3390/nu9111271 · Cited by 157 · see citing works
Atheroprotective effects of (poly)phenols: a focus on cell cholesterol metabolism
Zanotti, I., Dall’Asta, M., Mena, P. R., Mele, L., Bruni, R., Ray, S., & Rio, D. D. (2014) · Food & Function · doi:10.1039/c4fo00670d · Cited by 158 · see citing works
Nuts and CVD
Ros, E. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114514003924 · Cited by 156 · see citing works
A systematic review and meta-analysis of nut consumption and incident risk of CVD and all-cause mortality
Mayhew, A. J., de Souza, R. J., Meyre, D., Anand, S. S., & Mente, A. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114515004316 · Cited by 147 · see citing works
Effect of tree nuts on metabolic syndrome criteria: a systematic review and meta-analysis of randomised controlled trials
Blanco Mejia, S., Kendall, C. W. C., Viguiliouk, E., Augustin, L. S., Ha, V., Cozma, A. I., Mirrahimi, A., Maroleanu, A., Chiavaroli, L., Leiter, L. A., et al. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-004660 · Cited by 150 · see citing works
Nutrition Therapy
Dworatzek, P. D. N., Arcudi, K., Gougeon, R., Husein, N., Sievenpiper, J. L., & Williams, S. L. (2013) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2013.01.019 · Cited by 149 · see citing works
Effects of walnut consumption on blood lipids and other cardiovascular risk factors: An updated meta-analysis and systematic review of controlled trials
Guasch-Ferré, M., Li, J., Hu, F. B., Salas-Salvadó, J., & Tobias, D. K. (2018) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy091 · Cited by 147 · see citing works
Dietary composition and nutrient content of the New Nordic Diet
Mithril, C. E., Dragsted, L. O., Meyer, C., Tetens, I., Biltoft-Jensen, A. P., & Astrup, A. V. (2012) · Public Health Nutrition · doi:10.1017/s1368980012004521 · Cited by 147 · see citing works
Consumption of Plant Seeds and Cardiovascular Health
Ros, E., & Hu, F. B. (2013) · Circulation · doi:10.1161/circulationaha.112.001119 · Cited by 146 · see citing works
Vegetarian and vegan diets and the risk of cardiovascular disease, ischemic heart disease and stroke: a systematic review and meta-analysis of prospective cohort studies
Dybvik, J. S., Svendsen, M., & Aune, D. (2023) · European Journal of Nutrition · doi:10.1007/s00394-022-02942-8 · Cited by 150 · see citing works
Nutrition attributes and health effects of pistachio nuts
Bulló, M., Juanola‐Falgarona, M., Hernández‐Alonso, P., & Salas‐Salvadó, J. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114514003250 · Cited by 143 · see citing works
Effect of Plant Protein on Blood Lipids: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Li, S. S., Blanco Mejia, S., Lytvyn, L., Stewart, S. E., Viguiliouk, E., Ha, V., de Souza, R. J., Leiter, L. A., Kendall, C. W. C., Jenkins, D. J. A., et al. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.006659 · Cited by 139 · see citing works
Influence of roasting conditions on health-related compounds in different nuts
Schlörmann, W., Birringer, M., Böhm, V., Löber, K., Jahreis, G., Stefan Lorkowski, A., Müller, A. K., Schöne, F., & Glei, M. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.02.017 · Cited by 135 · see citing works
The Contribution of Fruit and Vegetable Consumption to Human Health
Yahia, E. M. (2009) · Wiley eBooks · doi:10.1002/9780813809397.ch1 · Cited by 136 · see citing works
Nuts: Natural Pleiotropic Nutraceuticals
Ros, E., Singh, A., & O’Keefe, J. H. (2021) · Nutrients · doi:10.3390/nu13093269 · Cited by 135 · see citing works
Nuts and Berries for Heart Health
Ros, E., Tapsell, L. C., & Sabaté, J. (2010) · Current Atherosclerosis Reports · doi:10.1007/s11883-010-0132-5 · Cited by 130 · see citing works
Almond Consumption and Cardiovascular Risk Factors in Adults with Prediabetes
Wien, M., Bleich, D., Raghuwanshi, M. P., Gould-Forgerite, S., Gomes, J., Couch, L. M., & Oda, K. (2010) · Journal of the American College of Nutrition · doi:10.1080/07315724.2010.10719833 · Cited by 130 · see citing works
Role of Walnuts in Maintaining Brain Health with Age
Poulose, S. M., Miller, M. G., & Shukitt‐Hale, B. (2014) · Journal of Nutrition · doi:10.3945/jn.113.184838 · Cited by 129 · see citing works
Nut consumption, weight gain and obesity: Epidemiological evidence
Martínez‐González, M. Á., & Bes‐Rastrollo, M. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.11.005 · Cited by 129 · see citing works
Associations between nut consumption and inflammatory biomarkers,
Yu, Z., Malik, V., Keum, N., Hu, F. B., Giovannucci, E. L., Stampfer, M. J., Willett, W. C., Fuchs, C. S., & Bao, Y. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.134205 · Cited by 129 · see citing works
Beneficial Effect of Pistachio Consumption on Glucose Metabolism, Insulin Resistance, Inflammation, and Related Metabolic Risk Markers: A Randomized Clinical Trial
Hernández‐Alonso, P., Salas-Salvadó, J., Baldrich-Mora, M., Juanola-Falgarona, M., & Bulló, M. (2014) · Diabetes Care · doi:10.2337/dc14-1431 · Cited by 127 · see citing works
Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions
Berryman, C. E., Preston, A. G., Karmally, W., Deckelbaum, R. J., & Kris‐Etherton, P. M. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00383.x · Cited by 125 · see citing works
Evaluating and adapting the Mediterranean diet for non-Mediterranean populations: A critical appraisal
Hoffman, R. M., & Gerber, M. (2013) · Nutrition Reviews · doi:10.1111/nure.12040 · Cited by 128 · see citing works
Brazilian nut consumption improves selenium status and glutathione peroxidase activity and reduces atherogenic risk in obese women
Cominetti, C., de Bortoli, M. C., Junior, A. B. G., & Cozzolino, S. M. F. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.05.005 · Cited by 124 · see citing works
Acute Consumption of Walnuts and Walnut Components Differentially Affect Postprandial Lipemia, Endothelial Function, Oxidative Stress, and Cholesterol Efflux in Humans with Mild Hypercholesterolemia
Berryman, C. E., Grieger, J. A., West, S. G., Chen, C.-Y. O., Blumberg, J. B., Rothblat, G. H., Sankaranarayanan, S., & Kris‐Etherton, P. M. (2013) · Journal of Nutrition · doi:10.3945/jn.112.170993 · Cited by 124 · see citing works
Effects of Walnuts on Endothelial Function in Overweight Adults with Visceral Obesity: A Randomized, Controlled, Crossover Trial
Katz, D. L., Davidhi, A., Ma, Y., Kavak, Y., Bifulco, L., & Njike, V. Y. (2012) · Journal of the American College of Nutrition · doi:10.1080/07315724.2012.10720468 · Cited by 123 · see citing works
Functional Food and Cardiovascular Disease Prevention and Treatment: A Review
Asgary, S., Rastqar, A., & Keshvari, M. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2017.1410867 · Cited by 132 · see citing works
Development of the food-based Lifelines Diet Score (LLDS) and its application in 129,369 Lifelines participants
Vinke, P. C., Corpeleijn, E., Dekker, L. H., Jacobs, D. R., Navis, G. J., & Kromhout, D. (2018) · European Journal of Clinical Nutrition · doi:10.1038/s41430-018-0205-z · Cited by 118 · see citing works
Cross-Sectional Assessment of Nut Consumption and Obesity, Metabolic Syndrome and Other Cardiometabolic Risk Factors: The PREDIMED Study
Ibarrola-Jurado, N., Bulló, M., Guasch‐Ferré, M., Ros, E., Martínez‐González, M. Á., Corella, D., Fiol, M., Wärnberǵ, J., Estruch, R., Román, P., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057367 · Cited by 115 · see citing works
Effects of Daily Almond Consumption on Cardiometabolic Risk and Abdominal Adiposity in Healthy Adults With Elevated LDL‐Cholesterol: A Randomized Controlled Trial
Berryman, C. E., West, S. G., Fleming, J. A., Bordi, P. L., & Kris‐Etherton, P. M. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.114.000993 · Cited by 114 · see citing works
Dietary Patterns and Cardiometabolic Outcomes in Diabetes: A Summary of Systematic Reviews and Meta-Analyses
Kahleova, H., Salas-Salvadó, J., Rahelić, D., Kendall, C. W., Rembert, E., & Sievenpiper, J. L. (2019) · Nutrients · doi:10.3390/nu11092209 · Cited by 114 · see citing works
Nuts as a Replacement for Carbohydrates in the Diabetic Diet
Jenkins, D. J. A., Kendall, C. W. C., Banach, M. S., Srichaikul, K., Vidgen, E., Mitchell, S., Parker, T. L., Nishi, S. K., Bashyam, B., de Souza, R. J., et al. (2011) · Diabetes Care · doi:10.2337/dc11-0338 · Cited by 109 · see citing works
Retracted
Dietary habits, lipoprotein metabolism and cardiovascular disease: From individual foods to dietary patterns
Gómez-Delgado, F., Katsiki, N., López‐Miranda, J., & Pérez‐Martínez, P. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1764487 · Cited by 109 · see citing works
Effect of a 6-month vegan low-carbohydrate (‘Eco-Atkins’) diet on cardiovascular risk factors and body weight in hyperlipidaemic adults: A randomised controlled trial
Jenkins, D. J. A., Wong, J. M. W., Kendall, C. W. C., Esfahani, A., Ng, V. W. Y., Leong, T. C. K., Faulkner, D. A., Vidgen, E., Paul, G., Mukherjea, R., et al. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-003505 · Cited by 109 · see citing works
Dietary Fats and Chronic Noncommunicable Diseases
Billingsley, H., Carbone, S., & Lavie, C. J. (2018) · Nutrients · doi:10.3390/nu10101385 · Cited by 108 · see citing works
Consumption of Nuts and Seeds and Health Outcomes Including Cardiovascular Disease, Diabetes and Metabolic Disease, Cancer, and Mortality: An Umbrella Review
Balakrishna, R., Bjørnerud, T., Bemanian, M., Aune, D., & Fadnes, L. T. (2022) · Advances in Nutrition · doi:10.1093/advances/nmac077 · Cited by 103 · see citing works
Evaluation of the Phenolic Profile of Castanea sativa Mill. By-Products and Their Antioxidant and Antimicrobial Activity against Multiresistant Bacteria
SILVA, V. Y. N. E. D., Falco, V., Días, M. I., Barros, L., Silva, A., Capita, R., Alonso‐Calleja, C., Amaral, J. S., Igrejas, G., Ferreira, I. C. F. R., et al. (2020) · Antioxidants · doi:10.3390/antiox9010087 · Cited by 102 · see citing works
Clinical Practice Guidelines for Healthy Eating for the Prevention and Treatment of Metabolic and Endocrine Diseases in Adults: Cosponsored by the American Association of Clinical Endocrinologists/The American College of Endocrinology and the Obesity Society Executive Summary
González-Campoy, J. M., Jeor, S. T. S., CASTORINO, K. N., Ebrahim, A., Hurley, D., Jovanovič, L., Mechanick, J. I., Petak, S. M., Yu, Y., Harris, K. A., et al. (2013) · Endocrine Practice · doi:10.4158/ep13155.esgl · Cited by 101 · see citing works
Clinical Practice Guidelines for Healthy Eating for the Prevention and Treatment of Metabolic and Endocrine Diseases in Adults: Cosponsored by the American Association of Clinical Endocrinologists/The American College of Endocrinology and the Obesity Society
González-Campoy, J. M., CASTORINO, K. N., Ebrahim, A., Hurley, D., Jovanovič, L., Mechanick, J. I., Petak, S. M., Yu, Y., Jeor, S. T. S., Harris, K. A., et al. (2013) · Endocrine Practice · doi:10.4158/ep13155.gl · Cited by 101 · see citing works
A randomized trial of the effects of an almond-enriched, hypocaloric diet in the treatment of obesity
Foster, G. D., Shantz, K. L., Veur, S. S. V., Oliver, T. L., Lent, M. R., Virus, A., Szapary, P. O., Rader, D. J., Zemel, B. S., & Tsai, A. G. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.037895 · Cited by 99 · see citing works
Hazelnut-enriched diet improves cardiovascular risk biomarkers beyond a lipid-lowering effect in hypercholesterolemic subjects
Örem, A., Yücesan, F. B., Örem, C., Akçan, B., Kural, B. V., Alasalvar, C., & Shahidi, F. (2012) · Journal of clinical lipidology · doi:10.1016/j.jacl.2012.10.005 · Cited by 99 · see citing works
Tree Nut consumption is associated with better adiposity measures and cardiovascular and metabolic syndrome health risk factors in U.S. Adults: NHANES 2005–2010
O’Neil, C. E., Fulgoni, V. L. I., & Nicklas, T. A. (2015) · Nutrition Journal · doi:10.1186/s12937-015-0052-x · Cited by 98 · see citing works
Nut Consumption in Relation to Cardiovascular Disease Incidence and Mortality Among Patients With Diabetes Mellitus
Liu, G., Guasch‐Ferré, M., Hu, Y., Li, Y., Hu, F. B., Rimm, E. B., Manson, J. E., Rexrode, K. M., & Sun, Q. (2019) · Circulation Research · doi:10.1161/circresaha.118.314316 · Cited by 92 · see citing works
Effects of pistachios on the lipid/lipoprotein profile, glycemic control, inflammation, and endothelial function in type 2 diabetes: A randomized trial
Sauder, K. A., McCrea, C. E., Ulbrecht, J. S., Kris‐Etherton, P. M., & West, S. G. (2015) · Metabolism · doi:10.1016/j.metabol.2015.07.021 · Cited by 93 · see citing works
Walnut-enriched diet reduces fasting non-HDL-cholesterol and apolipoprotein B in healthy Caucasian subjects: A randomized controlled cross-over clinical trial
Li-ya, W., Piotrowski, K., Rau, T., Waldmann, E., Broedl, U. C., Demmelmair, H., Koletzko, B. V., Stark, R. G., Nagel, J. M., Mantzoros, C. S., et al. (2013) · Metabolism · doi:10.1016/j.metabol.2013.11.005 · Cited by 90 · see citing works
Nuts and Cardiovascular Disease
Bitok, E., & Sabaté, J. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.05.003 · Cited by 89 · see citing works
Nuts Improve Diet Quality Compared to Other Energy-Dense Snacks While Maintaining Body Weight
Tey, S. L., Brown, R. C., Gray, A. R., Chisholm, A. W., & Delahunty, C. M. (2011) · Journal of Nutrition and Metabolism · doi:10.1155/2011/357350 · Cited by 88 · see citing works
Effects of adiposity on plasma lipid response to reductions in dietary saturated fatty acids and cholesterol
Flock, M. R., Green, M. H., & Kris-Etherton, P. M. (2011) · Advances in Nutrition · doi:10.3945/an.111.000422 · Cited by 82 · see citing works
Advances in Crop Improvement and Delivery Research for Nutritional Quality and Health Benefits of Groundnut (Arachis hypogaea L.)
Ojiewo, C. O., Janila, P., Bhatnagar‐Mathur, P., Pandey, M. K., Desmae, H., Okori, P., Mwololo, J. K., Ajeigbe, H. A., Njuguna‐Mungai, E., Muricho, G., et al. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.00029 · Cited by 86 · see citing works

Effect of nut consumption on blood lipids: An updated systematic review and meta-analysis of randomized controlled trials
Nishi, S. K., Paz‐Graniel, I., Ni, J., Valle‐Hita, C., Khoury, N., García-Gavilán, J. F., Babió, N., & Salas‐Salvadó, J. (2024) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2024.10.009 · Cited by 13 · see citing works
A Systematic Review of the Effects of Nuts on Blood Lipid Profiles in Humans
Mukuddem-Petersen, J., Stonehouse, W., & Jerling, J. C. (2005) · Journal of Nutrition · doi:10.1093/jn/135.9.2082 · Cited by 211 · see citing works
Effects of Nut Consumption on Blood Lipids and Lipoproteins: A Comprehensive Literature Update
Guasch‐Ferré, M., Tessier, A., Petersen, K. S., Sapp, P. A., Tapsell, L. C., Salas‐Salvadó, J., Ros, E., & Kris‐Etherton, P. M. (2023) · Nutrients · doi:10.3390/nu15030596 · Cited by 37 · see citing works
Effects of nut consumption on blood lipid profile: A meta-analysis of randomized controlled trials
Gunathilake, M. N., Van, N. T. H., & Kim, J. (2022) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.01.006 · Cited by 14 · see citing works
Effect of Tree Nuts Consumption on Serum Lipid Profile in Hyperlipidemic Individuals: A Systematic Review
Altamimi, M., Zidan, S. J., & Badrasawi, M. (2020) · Nutrition and Metabolic Insights · doi:10.1177/1178638820926521 · Cited by 31 · see citing works

Authors: Sabaté, J.
Affiliations: Loma Linda University (US)
Corresponding author: Sabaté, Joan
ORCID: Sabaté, Joan
Venue: Archives of Internal Medicine
Publisher: American Medical Association (AMA)
Published: 2010-05-10
Volume: 170
Issue: 9
Pages: 821
ISSN: 0003-9926 (ISSN-L)
DOI: 10.1001/archinternmed.2010.79
OpenAlex: W2134454487
Cited by: 422
References: 52
Citations by year: 2026: 9 · 2025: 15 · 2024: 11 · 2023: 17 · 2022: 29 · 2021: 25 · 2020: 25 · 2019: 32 · 2018: 28 · 2017: 28 · 2016: 22 · 2015: 35 · 2014: 43 · 2013: 34 · 2012: 35
FWCI: 30.64
Type: journal article
Language: en
Open access: closed
Locations: Archives of Internal Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Nuts composition and effects
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
Keywords: nut consumption, serum lipids, LDL cholesterol, HDL cholesterol, triglycerides, total cholesterol, hypercholesterolemia, coronary artery disease, dose-response relationship, body mass index, Western diet, dietary intervention, hypolipidemic effect
MeSH terms: Adult, Aged, Aged, 80 and over, Cholesterol, Feeding Behavior, Female, Humans, Hyperlipidemias, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Nuts, Triglycerides, Linear Models

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nut Consumption and Blood Lipid Levels: A Pooled Analysis of 25 Intervention Trials

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks