Brief Physician Advice for Problem Alcohol Drinkers: A Randomized Controlled Trial in Community-Based Primary Care Practices
Abstract
Objective. —Project TrEAT (Trial for Early Alcohol Treatment) was designed to test the efficacy of brief physician advice in reducing alcohol use and health care utilization in problem drinkers. Design. —Randomized controlled clinical trial with 12-month follow-up. Setting. —A total of 17 community-based primary care practices (64 physicians) located in 10 Wisconsin counties. Participants. —Of the 17 695 patients screened for problem drinking, 482 men and 292 women met inclusion criteria and were randomized into a control (n=382) or an experimental (n=392) group. A total of 723 subjects (93%) participated in the 12-month follow-up procedures. Intervention. —The intervention consisted of two 10- to 15-minute counseling visits delivered by physicians using a scripted workbook that included advice, education, and contracting information. Main Outcome Measures. —Alcohol use measures, emergency department visits, and hospital days. Results. —There were no significant differences between groups at baseline on alcohol use, age, socioeconomic status, smoking status, rates of depression or anxiety, frequency of conduct disorders, lifetime drug use, or health care utilization. At the time of the 12-month follow-up, there were significant reductions in 7-day alcohol use (mean number of drinks in previous 7 days decreased from 19.1 at baseline to 11.5 at 12 months for the experimental group vs 18.9 at baseline to 15.5 at 12 months for controls;t=4.33;P<.001), episodes of binge drinking (mean number of binge drinking episodes during previous 30 days decreased from 5.7 at baseline to 3.1 at 12 months for the experimental group vs 5.3 at baseline to 4.2 at 12 months for controls;t=2.81;P<.001), and frequency of excessive drinking (percentage drinking excessively in previous 7 days decreased from 47.5% at baseline to 17.8% at 12 months for the experimental group vs 48.1% at baseline to 32.5% at 12 months for controls;t=4.53;P<.001). The ϰ2test of independence revealed a significant relationship between group status and length of hospitalization over the study period for men (P<.01). Conclusions. —This study provides the first direct evidence that physician intervention with problem drinkers decreases alcohol use and health resource utilization in the US health care system.
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Power calculations used a published effect size of 0.33; a sample of 900 gave more than 0.80 power to detect low-to-moderate effects with a 0.05 type I error rate.
“Power calculations were based on published data38 indicating an expected effect of 0.33 in reduction of alcohol use between the experimental and control conditions. A total sample of 900 patients provided power (>0.80) to detect the hypothesized low-to moderate-sized effects (assuming a type I error of 0.05).”
From A Brief Intervention Reduces Hazardous and Harmful Drinking in Emergency Department Patients (2012) · cites this paper as [38]
A total of 52 studies met our inclusion criteria.
“A total of 52 studies met our inclusion criteria, with three studies presenting different outcomes for the same data and therefore considered as one.35–37”
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- Authors
- Fleming, M. F.
- Corresponding author
- Fleming, Michael F.
- ORCID
- Fleming, Michael F.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1997-04-02
- Volume
- 277
- Issue
- 13
- Pages
- 1039
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W4294294187
- Cited by
- 538
- References
- 1
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 8 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 7 · 2019: 7 · 2018: 11 · 2017: 10 · 2016: 12 · 2015: 15 · 2014: 15 · 2013: 14 · 2012: 21
- FWCI
- 27.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (AA08512-01A)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- problem drinking, alcohol consumption reduction, physician counseling, binge drinking, excessive drinking, health care utilization, emergency department visits, hospitalization, primary care, alcohol screening, community-based primary care, gender differences
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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