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Magnetic Nanoparticle Facilitated Drug Delivery for Cancer Therapy with Targeted and Image‐Guided Approaches

Huang, Jing, Li, Yuancheng, Orza, Anamaria, Lu, Qiong, Guo, Peng, Wang, Liya, Yang, Lily, Mao, Hui·2016·Advanced Functional Materials
DOI 10.1002/adfm.201504185PMC PMC5077153
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Abstract

With rapid advances in nanomedicine, magnetic nanoparticles (MNPs) have emerged as a promising theranostic tool in biomedical applications, including diagnostic imaging, drug delivery and novel therapeutics. Significant preclinical and clinical research has explored their functionalization, targeted delivery, controllable drug release and image‐guided capabilities. To further develop MNPs for theranostic applications and clinical translation in the future, we attempt to provide an overview of the recent advances in the development and application of MNPs for drug delivery, specifically focusing on the topics concerning the importance of biomarker targeting for personalized therapy and the unique magnetic and contrast‐enhancing properties of theranostic MNPs that enable image‐guided delivery. The common strategies and considerations to produce theranostic MNPs and incorporate payload drugs into MNP carriers are described. The notable examples are presented to demonstrate the advantages of MNPs in specific targeting and delivering under image guidance. Furthermore, current understanding of delivery mechanisms and challenges to achieve efficient therapeutic efficacy or diagnostic capability using MNP‐based nanomedicine are discussed.

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Research works printed but not linked: 163

  1. 10.1002/ddr.20067 · DOI
  2. 10.1016/j.addr.2008.03.018 · DOI
  3. 10.1016/j.addr.2009.11.002 · DOI
  4. 10.1093/annonc/mdl104 · DOI
  5. 10.1021/nn300456z · DOI
  6. 10.1021/cm960157j · DOI
  7. 10.1021/ja001628c · DOI
  8. 10.1021/cm060805r · DOI
  9. 10.1002/smll.200800261 · DOI
  10. 10.1021/la0008636 · DOI
  11. 10.1039/b712795b · DOI
  12. 10.1021/nn102762f · DOI
  13. 10.1002/adfm.201001450 · DOI
  14. 10.1021/am400713j · DOI
  15. 10.1021/nn301215q · DOI
  16. 10.1021/ja1022267 · DOI
  17. 10.1021/nn1029229 · DOI
  18. 10.1002/chem.201200030 · DOI
  19. 10.1002/adhm.201300549 · DOI
  20. 10.1038/nnano.2014.154 · DOI
  21. 10.1021/acsnano.5b01288 · DOI
  22. 10.1016/S1056-8719(00)00107-6 · DOI
  23. 10.1002/jbm.a.34014 · DOI
  24. 10.1016/j.biomaterials.2014.10.059 · DOI
  25. 10.1039/b810061f · DOI
  26. 10.1016/j.colsurfb.2012.10.041 · DOI
  27. 10.1016/j.biomaterials.2008.07.004 · DOI
  28. 10.7150/thno.9199 · DOI
  29. 10.1016/j.jcis.2011.06.086 · DOI
  30. 10.1039/c2nr11918h · DOI
  31. 10.1002/smll.200600009 · DOI
  32. 10.1021/nn3043463 · DOI
  33. 10.1016/j.actbio.2007.05.011 · DOI
  34. 10.1002/anie.201306724 · DOI
  35. 10.1021/ar200084x · DOI · Paper page
  36. 10.1002/adhm.201300122 · DOI
  37. 10.1016/j.biomaterials.2010.04.043 · DOI
  38. Rao Y.‐f., 2015, Small, 11
  39. 10.1158/0008-5472.CAN-06-4762 · DOI
  40. 10.1016/j.jviromet.2007.08.028 · DOI
  41. 10.1088/0957-4484/19/40/405102 · DOI
  42. Mykhaylyk O., 2008, Curr. Opin. Mol. Ther., 10, 493
  43. 10.1002/jgm.577 · DOI
  44. 10.1002/adfm.200801844 · DOI
  45. 10.1021/ja0516460 · DOI
  46. Frascione D., 2012, Int. J. Nanomed., 7, 2349
  47. 10.1016/j.biomaterials.2014.01.041 · DOI
  48. 10.1002/smll.201401927 · DOI
  49. 10.1021/nn406590q · DOI
  50. Matsumura Y., 1986, Cancer Res., 46, 6387
  51. 10.1016/j.drudis.2006.07.005 · DOI · Paper page
  52. 10.1016/j.addr.2010.04.009 · DOI
  53. 10.1016/j.jconrel.2014.03.057 · DOI · Paper page
  54. Iwai K., 1984, Cancer Res., 44, 2115
  55. 10.1002/1097-0142(19841201)54:11<2367::AID-CNCR2820541111>3.0.CO;2-F · DOI
  56. 10.1016/S0002-9440(10)65006-7 · DOI · Paper page
  57. 10.1073/pnas.95.8.4607 · DOI · Paper page
  58. 10.1038/nnano.2007.387 · DOI · Paper page
  59. 10.1007/12_026 · DOI
  60. 10.1016/S0065-2571(00)00013-3 · DOI · Paper page
  61. 10.1016/j.ejpb.2008.11.010 · DOI
  62. 10.1016/S0169-409X(00)00134-4 · DOI
  63. Gusev S. A., 1988, Tsitologiia, 30, 1022
  64. Campbell R. B., 2002, Cancer Res., 62, 6831
  65. 10.1021/cr300068p · DOI · Paper page
  66. 10.1021/mp300240m · DOI
  67. 10.3233/CBM-2009-0615 · DOI
  68. 10.1016/j.clim.2006.06.010 · DOI
  69. 10.1002/mrm.1910400209 · DOI
  70. 10.1016/j.nano.2011.08.017 · DOI
  71. 10.1002/cncr.26661 · DOI
  72. 10.1074/mcp.R400001-MCP200 · DOI
  73. 10.1007/s00775-008-0445-9 · DOI
  74. Chen H., 2013, Int. J. Nanomed., 8, 3781
  75. 10.1016/j.jmb.2007.05.011 · DOI
  76. 10.1016/S0022-1759(99)00161-1 · DOI
  77. 10.1002/smll.200800714 · DOI
  78. 10.1016/j.jconrel.2015.04.029 · DOI · Paper page
  79. 10.1038/nrm2821 · DOI
  80. 10.1166/jbn.2008.007 · DOI
  81. Yang L., 2009, Cancer Res., 69, 348S
  82. 10.1053/j.gastro.2009.01.006 · DOI
  83. 10.1016/j.jconrel.2010.10.030 · DOI
  84. 10.1038/am.2014.12 · DOI
  85. 10.1126/science.2200121 · DOI
  86. 10.1073/pnas.0602615103 · DOI
  87. 10.1158/0008-5472.CAN-04-2550 · DOI
  88. 10.1073/pnas.0809154105 · DOI
  89. Lupold S. E., 2002, Cancer Res., 62, 4029
  90. 10.1038/sj.bjc.6602668 · DOI
  91. 10.1016/S0169-409X(99)00062-9 · DOI
  92. 10.1016/S0168-3659(03)00215-3 · DOI
  93. 10.1021/bc050050z · DOI
  94. 10.1002/jbm.a.30781 · DOI
  95. 10.1002/jbm.a.31752 · DOI
  96. Li L., 2015, Drug Deliv.
  97. Peng X.‐H., 2008, Int. J. Nanomed., 3, 311
  98. 10.1038/nrc727 · DOI
  99. 10.1016/S0092-8674(02)00971-6 · DOI
  100. 10.1021/ar800243b · DOI
  101. 10.1039/C5NR04003E · DOI
  102. 10.1158/0008-5472.CAN-06-1668 · DOI
  103. 10.1016/j.biomaterials.2011.02.006 · DOI
  104. Laurent S., 2011, Int. J. Mol. Epid. and Gene., 2, 367
  105. 10.1073/pnas.1408556111 · DOI
  106. 10.1038/nbt1159 · DOI
  107. 10.1002/cmdc.200800091 · DOI
  108. 10.1021/jo300372q · DOI
  109. 10.1021/jo902637k · DOI
  110. 10.1002/adma.201305811 · DOI
  111. 10.1038/nm1101-1241 · DOI
  112. 10.1021/nl0502569 · DOI
  113. 10.1002/smll.200700784 · DOI
  114. 10.1021/bc060035 · DOI
  115. 10.1016/j.biomaterials.2009.08.045 · DOI
  116. 10.1021/bc800077y · DOI
  117. 10.1021/ja052337c · DOI
  118. 10.1021/ja4108287 · DOI
  119. 10.1158/0008-5472.CAN-14-1540 · DOI
  120. 10.7150/thno.11389 · DOI
  121. 10.2217/nnm.10.23 · DOI
  122. 10.1038/nnano.2010.250 · DOI
  123. 10.1038/nmat2442 · DOI · Paper page
  124. 10.3390/ijms13055554 · DOI · Paper page
  125. 10.1016/S0169-409X(02)00226-0 · DOI
  126. 10.1021/mp800051m · DOI · Paper page
  127. 10.2147/IJN.S26766 · DOI
  128. 10.1021/am900262j · DOI
  129. 10.1016/j.biomaterials.2010.03.036 · DOI
  130. 10.1021/nn3035155 · DOI
  131. 10.1021/la052851w · DOI
  132. 10.1002/adma.201404059 · DOI
  133. 10.1021/nn303030t · DOI
  134. 10.2147/IJN.S77642 · DOI
  135. 10.1002/adfm.201303345 · DOI
  136. 10.1038/ncomms9009 · DOI
  137. 10.1016/j.addr.2011.03.008 · DOI
  138. 10.1158/0008-5472.CAN-10-2070 · DOI
  139. 10.1002/smll.201201973 · DOI
  140. 10.1158/0008-5472.CAN-10-1022 · DOI
  141. 10.7150/thno.9436 · DOI
  142. 10.1002/jmri.22412 · DOI
  143. 10.1002/jmri.24453 · DOI
  144. 10.7150/thno.4006 · DOI
  145. 10.1021/nn4023119 · DOI
  146. 10.1016/j.jconrel.2015.01.028 · DOI
  147. 10.1021/nn102187v · DOI
  148. 10.1002/adma.201405634 · DOI
  149. 10.1002/adfm.201402338 · DOI
  150. 10.1002/adfm.201401451 · DOI
  151. 10.1016/j.biomaterials.2015.04.053 · DOI
  152. 10.1002/adfm.201402930 · DOI
  153. 10.2174/1568026614666140118203550 · DOI
  154. 10.1007/s11060-010-0389-0 · DOI
  155. 10.3109/02656731003745740 · DOI
  156. 10.1039/C4SC03080J · DOI
  157. 10.1002/adfm.201500464 · DOI
  158. 10.1016/j.biomaterials.2014.10.052 · DOI
  159. 10.1016/j.biomaterials.2014.07.064 · DOI
  160. 10.1002/adfm.201302463 · DOI
  161. 10.1039/C4CC10444G · DOI
  162. 10.1002/adfm.201303416 · DOI
  163. 10.1039/C4TB00811A · DOI

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Metadata

Authors
Huang, J., Li, Y., Orza, A., Lu, Q., Guo, P., Wang, L., Yang, L., & Mao, H.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2016-02-05
Volume
26
Issue
22
Pages
3818-3836
ISSN
  • 1616-301X
  • 1616-3028
DOI
10.1002/adfm.201504185
PMC
PMC5077153
Cited by
292
References
11
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Funders
NCI's Cancer Nanotechnology Platform Project (U01CA151810-05)

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