The impact of junk foods on the adolescent brain

Reichelt, Amy C.; Rank, Michelle M.

doi:10.1002/bdr2.1173

Cited by 102Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorEating Disorders and Behaviors

The impact of junk foods on the adolescent brain

Reichelt, Amy C., Rank, Michelle M.·2017·Birth Defects Research

DOI 10.1002/bdr2.1173

Open this paper in CoChat — free account

Abstract

Adolescence is a significant period of physical, social, and emotional development, and is characterized by prominent neurobiological changes in the brain. The maturational processes that occur in brain regions responsible for cognitive control and reward seeking may underpin excessive consumption of palatable high fat and high sugar “junk” foods during adolescence. Recent studies have highlighted the negative impact of these foods on brain function, resulting in cognitive impairments and altered reward processing. The increased neuroplasticity during adolescence may render the brain vulnerable to the negative effects of these foods on cognition and behavior. In this review, we describe the mechanisms by which junk food diets influence neurodevelopment during adolescence. Diet can lead to alterations in dopamine‐mediated reward signaling, and inhibitory neurotransmission controlled by γ‐aminobutyric acid (GABA), two major neurotransmitter systems that are under construction across adolescence. We propose that poor dietary choices may derail the normal adolescent maturation process and influence neurodevelopmental trajectories, which can predispose individuals to dysregulated eating and impulsive behaviors.

Integrity signals

Registry

Crossref · 10.1002/bdr2.1173

Cites

109 of 109 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Findings from human cohorts point to the importance of adequate nutrition and diet quality for adolescent brain and mental health.
“Findings from human cohorts point to the importance of adequate nutrition and diet quality for adolescent brain and mental health (291, 292).”
From Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health (2021) · cites this paper as [291]

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012
Ogden, C. L., Carroll, M. D., Kit, B. K., & Flegal, K. M. (2014) · JAMA · doi:10.1001/jama.2014.732 · Cited by 8,072 · see citing works
Brain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552 · see citing works
The adolescent brain and age-related behavioral manifestations
Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433 · see citing works
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Di Chiara, G., & Imperato, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5274 · Cited by 4,733 · see citing works
Emotion, Decision Making and the Orbitofrontal Cortex
Bechara, A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.295 · Cited by 3,589 · see citing works
The Adolescent Brain
Casey, B. J., Jones, R. M., & Hare, T. A. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.010 · Cited by 3,345 · see citing works
Why do many psychiatric disorders emerge during adolescence?
Paus, T., Keshavan, M., & Giedd, J. N. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2513 · Cited by 3,123 · see citing works
Understanding adolescence as a period of social–affective engagement and goal flexibility
Crone, E. A., & Dahl, R. E. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3313 · Cited by 2,507 · see citing works
Neocortical excitation/inhibition balance in information processing and social dysfunction
Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature · doi:10.1038/nature10360 · Cited by 2,454 · see citing works
Mapping cortical change across the human life span
Sowell, E. R., Peterson, B. S., Thompson, P. M., Welcome, S. E., Henkenius, A. L., & Toga, A. W. (2003) · Nature Neuroscience · doi:10.1038/nn1008 · Cited by 2,328 · see citing works
Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making
Bechara, A., Damasio, H., Damasio, A. R., & Lee, G. P. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-13-05473.1999 · Cited by 2,001 · see citing works
Food reward: brain substrates of wanting and liking
Berridge, K. C. (1996) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(95)00033-b · Cited by 1,901 · see citing works
Age differences in sensation seeking and impulsivity as indexed by behavior and self-report: Evidence for a dual systems model.
Steinberg, L., Albert, D., Cauffman, E., Banich, M., Graham, S., & Woolard, J. (2008) · Developmental Psychology · doi:10.1037/a0012955 · Cited by 1,542 · see citing works
Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
Johnson, P. M., & Kenny, P. J. (2010) · Nature Neuroscience · doi:10.1038/nn.2519 · Cited by 1,495 · see citing works
The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
Ikemoto, S., & Panksepp, J. (1999) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00023-5 · Cited by 1,450 · see citing works
Global obesity: trends, risk factors and policy implications
Malik, V., Willett, W. C., & Hu, F. B. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.199 · Cited by 1,418 · see citing works
Age differences in future orientation and delay discounting
Steinberg, L., Graham, S., O’Brien, L., Woolard, J., Cauffman, E., & Banich, M. (2009) · Child Development · doi:10.1111/j.1467-8624.2008.01244.x · Cited by 1,237 · see citing works
“Liking” and “wanting” food rewards: Brain substrates and roles in eating disorders
Berridge, K. C. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2009.02.044 · Cited by 1,147 · see citing works
Adolescent cortical development: A critical period of vulnerability for addiction
Crews, F., He, J., & Hodge, C. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.001 · Cited by 1,091 · see citing works
A time of change: behavioral and neural correlates of adolescent sensitivity to appetitive and aversive environmental cues
Somerville, L. H., Jones, R. M., & Casey, B. J. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.07.003 · Cited by 1,025 · see citing works
Mapping Continued Brain Growth and Gray Matter Density Reduction in Dorsal Frontal Cortex: Inverse Relationships during Postadolescent Brain Maturation
Sowell, E. R., Thompson, P. M., Tessner, K. D., & Toga, A. W. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-22-08819.2001 · Cited by 983 · cited 2× · see citing works
“This is measured as increases in cerebral white matter volumes, and it is suggested that this process is not completed in the PFC until 20 years of age or later (Sowell et al., 2001).”
Background
Ventral striatal control of appetitive motivation: role in ingestive behavior and reward-related learning
Kelley, A. E. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.11.015 · Cited by 942 · see citing works
Obesity and addiction: Neurobiological overlaps
Volkow, N. D., Wang, G. ‐., Tomasi, D., & Baler, R. D. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01031.x · Cited by 800 · see citing works
Corticostriatal-hypothalamic circuitry and food motivation: Integration of energy, action and reward
Kelley, A. E., Baldo, B. A., Pratt, W. E., & Will, M. J. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.08.066 · Cited by 752 · see citing works
Reward mechanisms in obesity: new insights and future directions
Kenny, P. J. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.016 · Cited by 748 · see citing works
Drug Addiction as a Pathology of Staged Neuroplasticity
Kalivas, P. W., & O’Brien, C. P. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301564 · Cited by 735 · see citing works
Food Advertising and Marketing Directed at Children and Adolescents in the US
Story, M., & French, S. (2004) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-1-3 · Cited by 725 · see citing works
Decision-making in the adolescent brain
Blakemore, S.-J., & Robbins, T. W. (2012) · Nature Neuroscience · doi:10.1038/nn.3177 · Cited by 711 · cited 1× · see citing works
“This is underpinned by the immature adolescent PFC, which impedes self-regulation of reward-driven behaviors during this life stage (Blakemore & Robbins, 2012; Casey et al., 2008).”
Background
Pleasures of the brain
Berridge, K. C. (2003) · Brain and Cognition · doi:10.1016/s0278-2626(03)00014-9 · Cited by 694 · see citing works
Neurobiology of the Adolescent Brain and Behavior: Implications for Substance Use Disorders
Casey, B. J., & Jones, R. M. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.08.017 · Cited by 692 · see citing works
Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity
Kanoski, S. E., & Davidson, T. L. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.12.003 · Cited by 674 · see citing works
Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence
Laviola, G., Macrı̀, S., Morley-Fletcher, S., & Adriani, W. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00006-x · Cited by 621 · see citing works
Development of the dopaminergic innervation in the prefrontal cortex of the rat
Kalsbeek, A., Voorn, P., Buijs, R. M., Pool, C. W., & Uylings, H. B. M. (1988) · Journal of Comparative Neurology · doi:10.1002/cne.902690105 · Cited by 545 · see citing works
Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell
Rada, P. V., Avena, N. M., & Hoebel, B. G. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.043 · Cited by 542 · see citing works
Adolescent risky decision-making: Neurocognitive development of reward and control regions
Van Leijenhorst, L., Moor, B. G., Op de Macks, Z. A., Rombouts, S. A. R. B., Westenberg, P. M., & Crone, E. A. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.02.038 · Cited by 467 · cited 1× · see citing works
“…GABAergic neurotransmission is proposed to contribute to behaviors typically seen in adolescents, such as impulsiveness, risk-taking (Schindler, Soden, Zweifel, & Clark, 2016; Van Leijenhorst et al., 2010), and susceptibility to development of psychiatric disorders (Caballero & Tseng, 2016).”
Background
Trends in Food Locations and Sources among Adolescents and Young Adults
Nielsen, S. (2002) · Preventive Medicine · doi:10.1006/pmed.2002.1037 · Cited by 441 · see citing works
The developmental mismatch in structural brain maturation during adolescence
Mills, K. L., Goddings, A.-L., Clasen, L. S., Giedd, J. N., & Blakemore, S.-J. (2014) · Developmental Neuroscience · doi:10.1159/000362328 · Cited by 440 · see citing works
The neuropsychology of ventral prefrontal cortex: Decision-making and reversal learning
Clark, L., Cools, R., & Robbins, T. W. (2004) · Brain and Cognition · doi:10.1016/s0278-2626(03)00284-7 · Cited by 439 · see citing works
Development of the prefrontal cortex during adolescence: Insights into vulnerable neural circuits in schizophrenia
Lewis, D. (1997) · Neuropsychopharmacology · doi:10.1016/s0893-133x(96)00277-1 · Cited by 388 · see citing works
Neonatal Insulin Action Impairs Hypothalamic Neurocircuit Formation in Response to Maternal High-Fat Feeding
Vogt, M. C., Paeger, L., Heß, S., Steculorum, S. M., Awazawa, M., Hampel, B., Neupert, S., Nicholls, H. T., Mauer, J., Hausen, A. C., et al. (2014) · Cell · doi:10.1016/j.cell.2014.01.008 · Cited by 358 · see citing works
Mechanisms contributing to prefrontal cortex maturation during adolescence
Caballero, A., Granberg, R., & Tseng, K. Y. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.013 · Cited by 357 · see citing works
Disinhibited Eating in Obese Adolescents Is Associated With Orbitofrontal Volume Reductions and Executive Dysfunction
Maayan, L., Hoogendoorn, C., Sweat, V., & Convit, A. (2011) · Obesity · doi:10.1038/oby.2011.15 · Cited by 345 · see citing works
Dopamine Modulation of Prefrontal Cortical Interneurons Changes during Adolescence
Tseng, K.-Y., & O'Donnell, P. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhl034 · Cited by 339 · see citing works
Comparative postnatal development of dopamine D1, D2 and D4 receptors in rat forebrain
Tarazi, F. I., & Baldessarini, R. J. (2000) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(99)00108-2 · Cited by 327 · see citing works
Desperately driven and no brakes: Developmental stress exposure and subsequent risk for substance abuse
Andersen, S. L., & Teicher, M. H. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.09.009 · Cited by 326 · see citing works
Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats
Boitard, C., Cavaroc, A., Sauvant, J., Aubert, A., Castanon, N., Layé, S., & Ferreira, G. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.03.005 · Cited by 324 · see citing works
Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: A tyrosine hydroxylase immunohistochemical analysis
Rosenberg, D. R., & Lewis, D. A. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903580306 · Cited by 319 · see citing works
Sex differences in dopamine receptor overproduction and elimination
Andersen, S. L., Rutstein, M. D., Benzo, J., Hostetter, J. C., & Teicher, M. H. (1997) · Neuroreport · doi:10.1097/00001756-199704140-00034 · Cited by 316 · see citing works
Developmental changes in dopamine neurotransmission in adolescence: Behavioral implications and issues in assessment
Wahlstrom, D., Collins, P., White, T., & Luciana, M. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.10.013 · Cited by 311 · see citing works
Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition
Morris, M. J., Beilharz, J. E., Maniam, J., Reichelt, A. C., & Westbrook, R. F. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.12.002 · Cited by 285 · see citing works
Self-citation
Postnatal development of monoamine content and synthesis in the cerebral cortex of rhesus monkeys
Goldman‐Rakic, P. S., & Brown, R. M. (1982) · Developmental Brain Research · doi:10.1016/0165-3806(82)90146-8 · Cited by 283 · see citing works
Prefrontal Cortex and Impulsive Decision Making
Kim, S., & Lee, D. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.07.005 · Cited by 276 · see citing works
Juvenile, but not adult exposure to high‐fat diet impairs relational memory and hippocampal neurogenesis in mice
Boitard, C., Etchamendy, N., Sauvant, J., Aubert, A., Tronel, S., Marighetto, A., Layé, S., & Ferreira, G. (2012) · Hippocampus · doi:10.1002/hipo.22032 · Cited by 258 · see citing works
Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal
Sharma, S., Fernandes, M. F., & Fulton, S. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.197 · Cited by 231 · see citing works
The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat
Kanoski, S. E., Meisel, R. L., Mullins, A. J., & Davidson, T. L. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.05.004 · Cited by 226 · see citing works
Effects of sucrose and high fructose corn syrup consumption on spatial memory function and hippocampal neuroinflammation in adolescent rats: Adolescent Sugar Intake Impairs Spatial Memory
Hsu, T. M., Konanur, V. R., Taing, L., Usui, R., Kayser, B. D., Goran, M. I., & Kanoski, S. E. (2015) · Hippocampus · doi:10.1002/hipo.22368 · Cited by 217 · see citing works
Child and adolescent obesity: Epidemiology and developmental perspectives
Adair, L. S. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.016 · Cited by 215 · see citing works
Sex steroids and connectivity in the human brain: A review of neuroimaging studies
Peper, J. S., van den Heuvel, M. P., Mandl, R. C. W., Pol, H. E. H., & van Honk, J. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.05.004 · Cited by 209 · see citing works
Fronto-striatal organization: defining functional and microstructural substrates of behavioural flexibility
Morris, L. S., Kundu, P., Dowell, N., Mechelmans, D. J., Favre, P., Irvine, M. A., Robbins, T. W., Daw, N., Bullmore, E. T., Harrison, N. A., et al. (2016) · Cortex · doi:10.1016/j.cortex.2015.11.004 · Cited by 198 · see citing works
Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood
Gass, J. T., Glen, W. B., McGonigal, J. T., Trantham-Davidson, H., Lopez, M. F., Randall, P. K., Yaxley, R., Floresco, S. B., & Chandler, L. J. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.109 · Cited by 197 · see citing works
Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response
Avena, N. M., Rada, P. V., Moise, N., & Hoebel, B. G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.12.037 · Cited by 195 · see citing works
Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals.
Francis, H., & Stevenson, R. J. (2011) · Behavioral Neuroscience · doi:10.1037/a0025998 · Cited by 190 · see citing works
PRECLINICAL STUDY: Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats
Schneider, M., Schömig, E., & Leweke, F. M. (2008) · Addiction Biology · doi:10.1111/j.1369-1600.2008.00117.x · Cited by 189 · see citing works
Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet.
Kanoski, S. E., & Davidson, T. L. (2010) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/a0017228 · Cited by 185 · see citing works
GABAergic Function as a Limiting Factor for Prefrontal Maturation during Adolescence
Caballero, A. C., & Tseng, K. Y. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.04.010 · Cited by 178 · see citing works
Changes in the dopaminergic innervation of monkey prefrontal cortex during late postnatal development: A tyrosine hydroxylase immunohistochemical study
Rosenberg, D. R., & Lewis, D. A. (1994) · Biological Psychiatry · doi:10.1016/0006-3223(94)90610-6 · Cited by 174 · see citing works
Affect regulation, brain development, and behavioral/emotional health in adolescence
Dahl, R. E. (2001) · CNS Spectrums · doi:10.1017/s1092852900022884 · Cited by 168 · see citing works
Delayed extinction and stronger reinstatement of cocaine conditioned place preference in adolescent rats, compared to adults.
Brenhouse, H. C., & Andersen, S. L. (2008) · Behavioral Neuroscience · doi:10.1037/0735-7044.122.2.460 · Cited by 155 · see citing works
Evidence of executive dysfunction in extremely obese adolescents: a pilot study
Lokken, K., Boeka, A. G., Austin, H. M., Gunstad, J., & Harmon, C. M. (2009) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2009.05.008 · Cited by 151 · see citing works
A four-day Western-style dietary intervention causes reductions in hippocampal-dependent learning and memory and interoceptive sensitivity
Attuquayefio, T., Stevenson, R. J., Oaten, M., & Francis, H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0172645 · Cited by 147 · see citing works
Post-Pubertal Disruption of Medial Prefrontal Cortical Dopamine–Glutamate Interactions in a Developmental Animal Model of Schizophrenia
Tseng, K.-Y., Lewis, B. L., Lipska, B. K., & O’Donnell, P. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.10.012 · Cited by 132 · see citing works
Prospective associations between dietary patterns and cognitive performance during adolescence
Nyaradi, A., Foster, J. K., Hickling, S., Li, J., Ambrosini, G. L., Jacques, A., & Oddy, W. H. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12209 · Cited by 132 · see citing works
Estrogen regulation of gene expression in the brain: a possible mechanism altering the response to psychostimulants in female rats
Zhou, W., Cunningham, K. A., & Thomas, M. L. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00134-1 · Cited by 130 · see citing works
Aging and the nigrostriatal dopamine system: a non-human primate study.
Irwin, I., DeLanney, L. E., McNeill, T. H., Chan, P., Forno, L. S., Murphy, G. M., Monte, D. A. D., Sandy, M. S., & Jw, L. (1994) · PubMed · Cited by 125 · see citing works
Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice
Kaczmarczyk, M. M., Machaj, A. S., Chiu, G. S., Lawson, M. A., Gainey, S. J., York, J. M., Meling, D. D., Martin, S. A., Kwakwa, K. A., Newman, A. F., et al. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.01.004 · Cited by 123 · see citing works
Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats
Friemel (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00039 · Cited by 117 · see citing works
Striatal dopamine sensitization to d-amphetamine in periadolescent but not in adult rats
Laviola, G., Pascucci, T., & Pieretti, S. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00430-5 · Cited by 115 · see citing works
Impact of adolescent sucrose access on cognitive control, recognition memory, and parvalbumin immunoreactivityPreprint
Reichelt, A. C., Killcross, S., Hambly, L. D., Morris, M. J., & Westbrook, R. F. (2015) · Learning & Memory · doi:10.1101/lm.038000.114 · Cited by 114 · see citing works
Self-citation
Enhanced striatal sensitivity to aversive reinforcement in adolescents versus adults
Galván, A., & McGlennen, K. M. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00326 · Cited by 111 · see citing works
Inhibitory control effects in adolescent binge eating and consumption of sugar-sweetened beverages and snacks
Ames, S. L., Kisbu‐Sakarya, Y., Reynolds, K. D., Boyle, S. C., Cappelli, C., Cox, M. G., Dust, M., Grenard, J. L., MacKinnon, D. P., & Stacy, A. W. (2014) · Appetite · doi:10.1016/j.appet.2014.06.013 · Cited by 106 · see citing works
Diet quality of US adolescents during the transition to adulthood: changes and predictors ,
Lipsky, L. M., Nansel, T. R., Haynie, D. L., Liu, D., Li, K., PRATT, C. A., Iannotti, R. J., Dempster, K. W., & Simons‐Morton, B. G. (2017) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.150029 · Cited by 102 · see citing works
Reversal of dopamine system dysfunction in response to high‐fat diet
Carlin, J., Hill‐Smith, T. E., Lucki, I., & Reyes, T. M. (2013) · Obesity · doi:10.1002/oby.20374 · Cited by 101 · see citing works
Sugar Overconsumption during Adolescence Selectively Alters Motivation and Reward Function in Adult Rats
Vendruscolo, L. F., Gueye, A. B., Darnaudéry, M., Ahmed, S. H., & Cador, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009296 · Cited by 96 · see citing works
Hedonic sensitivity in adolescent and adult rats: Taste reactivity and voluntary sucrose consumption
Wilmouth, C. E., & Spear, L. P. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.02.009 · Cited by 96 · see citing works
A high-fat diet decreases GABA concentration in the frontal cortex and hippocampus of rats
Sandoval‐Salazar, C., Ramı́rez-Emiliano, J., Trejo-Bahena, A., Oviedo-Solís, C. I., & Ortíz, M. S. S. (2016) · Biological Research · doi:10.1186/s40659-016-0075-6 · Cited by 95 · see citing works
Long-term risk preference and suboptimal decision making following adolescent alcohol use
Nasrallah, N. A., Yang, T. W. H., & Bernstein, I. L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906629106 · Cited by 94 · see citing works
Adolescent Maturational Transitions in the Prefrontal Cortex and Dopamine Signaling as a Risk Factor for the Development of Obesity and High Fat/High Sugar Diet Induced Cognitive Deficits
Reichelt, A. C. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00189 · Cited by 93 · see citing works
Self-citation
Developmental Differences in Acute Nigrostriatal and Mesocorticolimbic System Response to Haloperidol
Teicher, M. H., Barber, N. I., Gelbard, H. A., Gallitano, A. L., Campbell, A., Marsh, E. R., & Baldessarini, R. J. (1993) · Neuropsychopharmacology · doi:10.1038/npp.1993.53 · Cited by 91 · see citing works
Juvenile Obesity Enhances Emotional Memory and Amygdala Plasticity through Glucocorticoids
Boitard, C., Maroun, M., Tantot, F., Cavaroc, A., Sauvant, J., Marchand, A. R., Layé, S., Capuron, L., Darnaudéry, M., Castanon, N., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3122-14.2015 · Cited by 89 · see citing works
Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice
Krishna, S., Keralapurath, M. M., Lin, Z., Wagner, J. J., Serre, C. B. D. L., Harn, D. A., & Filipov, N. M. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.03.068 · Cited by 84 · see citing works
Age and sex differences in reward behavior in adolescent and adult rats
Hammerslag, L. R., & Gulley, J. M. (2013) · Developmental Psychobiology · doi:10.1002/dev.21127 · Cited by 82 · see citing works
Hypervulnerability of the adolescent prefrontal cortex to nutritional stress via reelin deficiency
Labouesse, M. A., Lassalle, O., Richetto, J., Iafrati, J., Weber‐Stadlbauer, U., Notter, T., Gschwind, T., Pujadas, L., Soriano, E., Reichelt, A. C., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.193 · Cited by 75 · see citing works
Self-citation
Chronic Alcohol Intake During Adolescence, but not Adulthood, Promotes Persistent Deficits in Risk-Based Decision Making
Schindler, A. G., Tsutsui, K. T., & Clark, J. J. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12404 · Cited by 67 · see citing works
Are We Addicted to Food?
Parigi, A. D., Chen, K., Salbe, A. D., Reiman, E. M., & Tataranni, P. A. (2003) · Obesity Research · doi:10.1038/oby.2003.68 · Cited by 61 · see citing works
Differential motivational profiles following adolescent sucrose access in male and female rats
Reichelt, A. C., Abbott, K. N., Westbrook, R. F., & Morris, M. J. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.01.038 · Cited by 58 · see citing works
Self-citation
Impaired fear extinction retention and increased anxiety-like behaviours induced by limited daily access to a high-fat/high-sugar diet in male rats: Implications for diet-induced prefrontal cortex dysregulation
Baker, K., & Reichelt, A. C. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.10.002 · Cited by 58 · see citing works
Self-citation
Impact of Early Consumption of High-Fat Diet on the Mesolimbic Dopaminergic System
Naneix, F., Tantot, F., Glangetas, C., Kaufling, J., Janthakhin, Y., Boitard, C., Smedt, V. D., Pape, J., Vancassel, S., Trifilieff, P., et al. (2017) · eNeuro · doi:10.1523/eneuro.0120-17.2017 · Cited by 57 · see citing works
Nutrient intake and biological maturation during adolescence. The Amsterdam growth and health longitudinal study.
Post, G. B., & Kemper, H. C. G. (1993) · PubMed · Cited by 56 · see citing works
Reversal of Alcohol-Induced Dysregulation in Dopamine Network Dynamics May Rescue Maladaptive Decision-making
Schindler, A. G., Soden, M. E., Zweifel, L. S., & Clark, J. J. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.4394-15.2016 · Cited by 52 · see citing works
Sex-specific effects of daily exposure to sucrose on spatial memory performance in male and female rats, and implications for estrous cycle stage
Abbott, K. N., Morris, M. J., Westbrook, R. F., & Reichelt, A. C. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.01.036 · Cited by 51 · see citing works
Self-citation
Age-dependent effects of repeated amphetamine exposure on working memory in rats
Sherrill, L. K., Stanis, J. J., & Gulley, J. M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.12.044 · Cited by 49 · see citing works
Eating High Fat Chow Decreases Dopamine Clearance in Adolescent and Adult Male Rats but Selectively Enhances the Locomotor Stimulating Effects of Cocaine in Adolescents
Baladi, M. G., Horton, R. E., Owens, W. A., Daws, L. C., & France, C. P. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv024 · Cited by 48 · see citing works
Effects of Sugar-Sweetened Beverages on Children
Bremer, A. A., & Lustig, R. H. (2012) · Pediatric Annals · doi:10.3928/00904481-20111209-09 · Cited by 48 · see citing works
Chronic high fat diet consumption impairs sensorimotor gating in mice
Labouesse, M. A., Weber‐Stadlbauer, U., Langhans, W., & Meyer, U. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.06.003 · Cited by 40 · see citing works
A Western Dietary Pattern Is Associated with Poor Academic Performance in Australian Adolescents
Nyaradi, A., Li, J., Hickling, S., Foster, J. K., Jacques, A., Ambrosini, G. L., & Oddy, W. H. (2015) · Nutrients · doi:10.3390/nu7042961 · Cited by 33 · see citing works
High-sucrose diets in male rats disrupt aspects of decision making tasks, motivation and spatial memory, but not impulsivity measured by operant delay-discounting
Wong, A., Dogra, V. R., & Reichelt, A. C. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.03.029 · Cited by 32 · see citing works
Self-citation
Effects of amphetamine exposure in adolescence or young adulthood on inhibitory control in adult male and female rats
Hammerslag, L. R., Waldman, A. J., & Gulley, J. M. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.01.015 · Cited by 27 · see citing works
Possible role of the dopamine D1 receptor in the sensorimotor gating deficits induced by high-fat diet
Wakabayashi, C., Numakawa, T., Ooshima, Y., et al. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4068-x · Cited by 19 · see citing works
Untitled work
Andersen (2000) · doi:10.1002/1098-2396(200008)37:2

Flagged first, then by citations

Sorted by citations

Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health
Berding, K., Vlckova, K., Marx, W., Schellekens, H., Stanton, C., Clarke, G., Jacka, F., Dinan, T. G., & Cryan, J. F. (2021) · Advances in Nutrition · doi:10.1093/advances/nmaa181 · Cited by 451 · see citing works
An intermittent hypercaloric diet alters gut microbiota, prefrontal cortical gene expression and social behaviours in rats
Reichelt, A. C., Loughman, A., Bernard, A., Raipuria, M., Abbott, K. N., Dachtler, J., Van, T. T. H., & Moore, R. J. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2018.1537169 · Cited by 49 · see citing works
Self-citation

Authors: Reichelt, A. C., & Rank, M. M.
Affiliations: RMIT University (AU)
Corresponding author: Reichelt, Amy C.
ORCID: Reichelt, Amy C.
Rank, Michelle M.
Venue: Birth Defects Research
Publisher: Wiley
Published: 2017-12
Volume: 109
Issue: 20
Pages: 1649-1658
ISSN: 2472-1727 (ISSN-L)
DOI: 10.1002/bdr2.1173
OpenAlex: W2777650050
Cited by: 102
References: 109
Citations by year: 2026: 12 · 2025: 16 · 2024: 16 · 2023: 6 · 2022: 15 · 2021: 12 · 2020: 9 · 2019: 7 · 2018: 9
FWCI: 0.76
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 17 d)
Locations: Birth Defects Research (publishedVersion)
PubMed (publishedVersion)
RMIT Research Repository (RMIT University Library) (submittedVersion)
Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
Figshare (submittedVersion)
Funders: Australian Research Council Discovery Early Career Research Award (DE140101071)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Keywords: junk food, adolescent brain, brain development, high-fat high-sugar diet, cognitive control, reward processing, dopamine, GABA, inhibitory neurotransmission, neuroplasticity, dysregulated eating, impulsive behavior
MeSH terms: Adolescent, Brain, Diet, Eating, Feeding Behavior, Humans, Adolescent Development

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The impact of junk foods on the adolescent brain

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks