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Immune and Inflammatory Role in Renal Disease
Open accessAbstract
Chronic and acute renal diseases, irrespective of the initiating cause, have inflammation and immune system activation as a common underlying mechanism. The purpose of this review is to provide a broad overview of immune cells and inflammatory proteins that contribute to the pathogenesis of renal disease, and to discuss some of the physiological changes that occur in the kidney as a result of immune system activation. An overview of common forms of acute and chronic renal disease is provided, followed by a discussion of common therapies that have anti‐inflammatory or immunosuppressive effects in the treatment of renal disease. © 2013 American Physiological Society. Compr Physiol 3:957‐976, 2013.
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Ishikura, H., Takahashi, C., Kanagawa, K., HIRATA, H., Imai, K., & Yoshiki, T. (1991) · Transplantation · doi:10.1097/00007890-199106000-00024 · Cited by 79
Hirschberg, R. R., & Wang, S. (2004) · Current Opinion in Nephrology & Hypertension · doi:10.1097/00041552-200501000-00008 · Cited by 78
Cell-mediated immune injury in the kidney: Acute nephritis induced in the rat by azobenzenearsonate
Rennke, H. G., Klein, P. S., Sandstrom, D. J., & Mendrick, D. L. (1994) · Kidney International · doi:10.1038/ki.1994.141 · Cited by 76
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Metadata
- Authors
- Imig, J. D., & Ryan, M. J.
- Venue
- Comprehensive Physiology
- Publisher
- Wiley
- Published
- 2013-04
- Volume
- 3
- Issue
- 2
- Pages
- 957-976
- ISSN
- 2040-4603 (ISSN-L)
- OpenAlex
- W1584309458
- Cited by
- 356
- References
- 245
- Type
- other
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.