Vasopressin cells in the bed nucleus of the stria terminalis of the rat: sex differences and the influence of androgens

van Leeuwen, F.W.; Caffe, A.R.; Vries, G.J. de

doi:10.1016/0006-8993(85)90348-8

Cited by 248Neuroendocrine regulation and behaviorHypothalamic control of reproductive hormonesSexual Differentiation and Disorders

Vasopressin cells in the bed nucleus of the stria terminalis of the rat: sex differences and the influence of androgens

van Leeuwen, F.W., Caffe, A.R., Vries, G.J. de·1985·Brain Research

DOI 10.1016/0006-8993(85)90348-8

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Abstract

A sex difference in the number of vasopressin-immunoreactive cells was found in the bed nucleus of the stria terminalis of the rat. The number of cells found in males exceeded the female corresponding value. A sharp decrease in the number of vasopressin-immunoreactive cells was noted 21 weeks after the castration of adult male rats. This decline could be reversed completely by a 5-week testosterone substitution therapy.

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Males have more AVP-expressing cells in the bed nucleus of the stria terminalis and medial amygdala and denser AVP-axonal projections to limbic brain regions, especially to the lateral septum.
“For example, males have more AVP-expressing cells in the bed nucleus of the stria terminalis and medial amygdala and denser AVP-axonal projections to limbic brain regions, especially to the lateral septum (De Vries et al., 1981; Van Leeuwen et al., 1985; Szot and Dorsa, 1993).”
From Sex-specific modulation of juvenile social play behavior by vasopressin and oxytocin depends on social context (2014) · cites this paper as Van Leeuwen et al., 1985
After gonadectomy, BST cells lose AVP immunoreactivity and can no longer be labeled for AVP mRNA unless the rats are treated with testosterone.
“After gonadectomy, BST cells lose their AVP immunoreactivity and can no longer be labeled for AVP mRNA unless the rats were treated with testosterone (De Vries et al., 1984, 1985;Van Leeuwen et al., 1985;Miller et al., 1989aMiller et al., , 1992)).”
From Sex differences in the effects of testosterone and its metabolites on vasopressin messenger RNA levels in the bed nucleus of the stria terminalis of rats (1994) · cites this paper as Van Leeuwen et al., 1985
Compared to females, males have more AVP-expressing cells in the BNST and MeA and denser AVP-axonal projections to limbic brain regions, especially the lateral septum.
“For example, compared to females, males have more AVP-expressing cells in the bed nucleus of the stria terminalis (BNST) and medial amygdala (MeA) and denser AVP-axonal projections to limbic brain regions, especially to the lateral septum (LS) (De Vries et al 1981; van Leeuwen et al., 1985; Szot & Dorsa, 1993).”
From Sex-specific modulation of juvenile social play by vasopressin (2013) · cites this paper as van Leeuwen et al., 1985
Male rats castrated as adults show reduced AVP-ir in the MeP/pBNST→LS circuit as well as reduced levels of intermale aggression.
“A potential role of AVP in male aggression is largely based on the observation that male rats castrated as adults show reduced AVP-ir in the MeP/pBNST→LS circuit as well as reduced levels of intermale aggression (Koolhaas, Moor, Hiemstra, & Bohus, 1991; Miller et al., 1992; Szot & Dorsa, 1993; van Leeuwen et al., 1985).”
From Quantitative mapping reveals age and sex differences in vasopressin, but not oxytocin, immunoreactivity in the rat social behavior neural network (2017) · cites this paper as van Leeuwen et al., 1985
In rats, males have more AVP-expressing neurons in the BNST and MeA and have a higher density of AVP-immunoreactive fibers in the LS and lateral habenular nucleus compared to females.
“In rats, males have more AVP-expressing neurons in the BNST and MeA (Szot & Dorsa, 1993; van Leeuwen, Caffe, & De Vries, 1985) and have a higher density of AVP-immunoreactive (AVP-ir) fibers in the lateral septum (LS) and lateral habenular nucleus (De Vries, Buijs, & Swaab, 1981) compared to females.”
From Quantitative mapping reveals age and sex differences in vasopressin, but not oxytocin, immunoreactivity in the rat social behavior neural network (2017) · cites this paper as van Leeuwen et al., 1985

The rat brain: A stereotaxic atlas of the forebrain and lower parts of the brain stem
König, J. F. R., & Klippel, R. (1986) · Medical Entomology and Zoology · Cited by 4,134 · see citing works
Atlas of estradiol‐concentrating cells in the central nervous system of the female rat
Pfaff, D. W., & Keiner, M. (1973) · The Journal of Comparative Neurology · doi:10.1002/cne.901510204 · Cited by 1,494 · see citing works
Anatomical neuroendocrinology
Holmes, R. L. (1982) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(82)90255-3 · Cited by 567 · see citing works
The origin of the vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum
de Vries, G. J., & Buijs, R. M. (1983) · Brain Research · doi:10.1016/0006-8993(83)90855-7 · Cited by 524 · see citing works
The vasopressinergic innervation of the brain in normal and castrated rats
DeVries, G. J., Buijs, R. M., van Leeuwen, F. W., Caffé, A. R., & Swaab, D. F. (1985) · Journal of Comparative Neurology · doi:10.1002/cne.902330206 · Cited by 522 · see citing works
Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretory system of the rat
Vandesande, F., & Dierickx, K. (1975) · Cell and Tissue Research · doi:10.1007/bf00218970 · Cited by 496 · see citing works
Immunofluorescence of vasopressin and oxytocin in the rat hypothalamo-neurohypophyseal system
Swaab, D. F., Pool, C. W., & Nijveldt, F. (1975) · Journal of Neural Transmission · doi:10.1007/bf01253126 · Cited by 323 · see citing works
Ontogeny of the vasopressinergic neurons of the suprachiasmatic nucleus and their extrahypothalamic projections in the rat brain–presence of a sex difference in the lateral septum
De Vries, G. J., Buds, R. M., & Swaab, D. F. (1981) · Brain Research · doi:10.1016/0006-8993(81)90989-6 · Cited by 319 · see citing works
Gonadal hormone actions on the morphology of the vasopressinergic innervation of the adult rat brain
De Vries, G. J., Buijs, R. M., & Sluiter, A. A. (1984) · Brain Research · doi:10.1016/0006-8993(84)91157-0 · Cited by 224 · see citing works
Vasopressin-immunoreactive cell bodies in the bed nucleus of the stria terminalis of the rat
van Leeuwen, F., & Caffé, R. (1983) · Cell and Tissue Research · doi:10.1007/bf00211473 · Cited by 206 · see citing works
Vasopressin-immunoreactive cells in the dorsomedial hypothalamic region, medial amygdaloid nucleus and locus coeruleus of the rat
Caffe´, A. R., & van Leeuwen, F. W. (1983) · Cell and Tissue Research · doi:10.1007/bf00222229 · Cited by 199 · see citing works
Vasopressin and oxytocin: distribution and putative functions in the brain
Buijs, R. M., De Vries, G. J., Van Leeuwen, F. W., & Swaab, D. F. (1983) · Progress in Brain Research · doi:10.1016/s0079-6123(08)64379-4 · Cited by 167 · see citing works
Copulatory behavior in male rats with lesions in the bed nucleus of the stria terminalis
Emery, D. E., & Sachs, B. D. (1976) · Physiology & Behavior · doi:10.1016/0031-9384(76)90044-5 · Cited by 151 · see citing works
The influence of androgens on the development of a sex difference in the vasopressinergic innervation of the rat lateral septum
Vries, G. J. D., Best, W., & Sluiter, A. A. (1983) · Developmental Brain Research · doi:10.1016/0165-3806(83)90019-6 · Cited by 141 · see citing works
Penile reflexes and copulatory behavior in male rats following lesions in the bed nucleus of the stria terminalis
Valcourt, R. J., & Sachs, B. D. (1979) · Brain Research Bulletin · doi:10.1016/0361-9230(79)90068-6 · Cited by 113 · see citing works
Sex Differences in Vasopressin and Other Neurotransmitter Systems in the Brain
De Vries, G. J., Buijs, R. M., & Van Leeuwen, F. W. (1984) · Progress in Brain Research · doi:10.1016/s0079-6123(08)64435-0 · Cited by 106 · see citing works
The Nucleus Interstitialis Striae Terminalis and the Nucleus Amygdaloideus Medialis: Prime Targets for Androgen in the Rat Forebrain*
Sheridan, P. J. (1979) · Endocrinology · doi:10.1210/endo-104-1-130 · Cited by 105 · see citing works
Distribution of Estrogen-Concentrating, Neurophysin-Containing Magnocellular Neurons in the Rat Hypothalamus as Demonstrated by a Technique Combining Steroid Autoradiography and Immunohistology in the Same Tissue
Rhodes, C. H., Morrell, J. I., & Pfaff, D. W. (2008) · Neuroendocrinology · doi:10.1159/000123195 · Cited by 96 · see citing works
Dual Action of Electrochemical Stimulation of the Bed Nucleus of the Stria terminalis on the Release of LH
Beltramino, C. A., & Taleisnik, S. (2008) · Neuroendocrinology · doi:10.1159/000123007 · Cited by 92 · see citing works
Interruption of septal connections: Effects on drinking, irritability, and copulation☆
Paxinos, G. (1976) · Physiology & Behavior · doi:10.1016/0031-9384(76)90273-0 · Cited by 32 · see citing works
Positive Feedback Sites of Estrogen in the Brain on Ovulation
Terasawa, E., & KAWAKAMI, M. (1974) · Endocrinologia Japonica · doi:10.1507/endocrj1954.21.51 · Cited by 31 · see citing works
Study on the Bed Nucleus of Stria Terminalis in Relation to Gonadotropin Control
KAWAKAMI, M., & Kimura, F. (1974) · Endocrinologia Japonica · doi:10.1507/endocrj1954.21.125 · Cited by 24 · see citing works
Sex differences in the brain — Relation between structure and function
Bruyn, G. W. (1985) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(85)90196-0 · Cited by 16 · see citing works

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1 of the 24 references couldn’t be matched to a known paper.

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Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425 · see citing works
The Medial Extended Amygdala in Male Reproductive Behavior A Node in the Mammalian Social Behavior Network
NEWMAN, S. W. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09271.x · Cited by 1,189 · see citing works
Social behavior functions and related anatomical characteristics of vasotocin/vasopressin systems in vertebrates
Goodson, J. L., & Bass, A. H. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00043-1 · Cited by 632 · see citing works
Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior
Dumais, K. M., & Veenema, A. H. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2015.04.003 · Cited by 520 · see citing works
“General Discussion We discussed above that various rodent species show consistent sex differences in VPimmunoreactive neurons and fiber density in the brain (rats: De Vries et al., 1983; Van Leeuwen et al., 1985; Miller et al., 1989; Wang & De Vries; mice: De Vries et al., 2002; Bakker et al., 2006; Gatewood et al., 2…”
BackgroundInfluential
Vasopressin: Behavioral roles of an “original” neuropeptide
Caldwell, H. K., Lee, H.-J., Macbeth, A. H., & Young, W. S. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.10.007 · Cited by 504 · see citing works
The neurobiology of pair bonding: Insights from a socially monogamous rodent
Young, K. A., Gobrogge, K. L., Liu, Y., & Wang, Z. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.07.006 · Cited by 389 · see citing works
Sex differences in circadian timing systems: implications for disease
Bailey, M., & Silver, R. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.11.003 · Cited by 348 · see citing works
Sex differences in subregions of the medial nucleus of the amygdala and the bed nucleus of the stria terminalis of the rat
Hines, M., Allen, L. S., & Gorski, R. A. (1992) · Brain Research · doi:10.1016/0006-8993(92)90068-k · Cited by 347 · see citing works
Sexual differentiation of central vasopressin and vasotocin systems in vertebrates: different mechanisms, similar endpoints
De Vries, G. J., & Panzica, G. C. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.07.050 · Cited by 346 · see citing works
Roles of steroid hormones and their receptors in structural organization in the nervous system
Kawata, M. (1995) · Neuroscience Research · doi:10.1016/0168-0102(96)81278-8 · Cited by 336 · see citing works
Vasopressin cells in the medial amygdala of the rat project to the lateral septum and ventral hippocampus
Caffé, A. R., van Leeuwen, F. W., & Luiten, P. G. M. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902610206 · Cited by 286 · see citing works
Sex difference in the bed nucleus of the stria terminalis of the human brain
Allen, L. S., & Gorski, R. A. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.903020402 · Cited by 281 · see citing works
Brain aging and Alzheimer's disease, “Wear and tear” versus “Use it or lose it”
Swaab, D. F. (1991) · Neurobiology of Aging · doi:10.1016/0197-4580(91)90008-8 · Cited by 276 · see citing works
Sexual dimorphism in the vomeronasal pathway and sex differences in reproductive behaviors
Segovia, S., & Guillamón, A. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90007-m · Cited by 274 · see citing works
Chronic ethanol ingestion decreases vasopressin mRNA in hypothalamic and extrahypothalamic nuclei of mouse brain
Gulya, K., Dave, J. R., & Hoffman, P. L. (1991) · Brain Research · doi:10.1016/0006-8993(91)90125-f · Cited by 265 · see citing works
Chemoarchitecture of the rat lateral septal nucleus 1Published on the World Wide Web on 2 June 1997. 1
Risold, P. Y., & Swanson, L. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00008-8 · Cited by 263 · see citing works
Sex Differences in Neurotransmitter Systems
Vries, G. J. D. (1990) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1990.tb00385.x · Cited by 226 · see citing works
Anatomy, Development, and Function of Sexually Dimorphic Neural Circuits in the Mammalian Brain
Vries, G. J. D., & Simerly, R. B. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50066-4 · Cited by 218 · see citing works
Functional sex differences (`sexual diergism') of central nervous system cholinergic systems, vasopressin, and hypothalamic–pituitary–adrenal axis activity in mammals: a selective review
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Social and individual recognition in rodents: Methodological aspects and neurobiological bases
Gheusi, G., Bluthé, R.-M., Goodall, G., & Dantzer, R. (1994) · Behavioural Processes · doi:10.1016/0376-6357(94)90060-4 · Cited by 206 · see citing works
Neuroendocrinology of social information processing in rats and mice
Choleris, E., Clipperton-Allen, A. E., Phan, A., & Kavaliers, M. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.003 · Cited by 205 · see citing works
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Tribollet, E., Audigier, S., Dubois-Dauphin, M., & Dreifuss, J. J. (1990) · Brain Research · doi:10.1016/0006-8993(90)90232-z · Cited by 203 · see citing works
Sexual dimorphism in the mammalian limbic system
Madeira, M. D., & Lieberman, A. R. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(94)00052-j · Cited by 202 · see citing works
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De Vries, G., Wang, Z., Bullock, N., & Numan, S. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01789.1994 · Cited by 193 · see citing works
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del Abril, A., Segovia, S., & Guillamón, A. (1987) · Developmental Brain Research · doi:10.1016/0165-3806(87)90110-6 · Cited by 184 · see citing works
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DEVRIES, G. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00402-0 · Cited by 169 · see citing works
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“Social play is thought to contribute to the development of social and emotional skills in humans and animals (Baldwin, 1986; Pellegrini, 1988; Vanderschuren et al., 1997; Bekoff & Byers, 1998; Van den Berg et al., 1999; Guralnick et al., 2006; Cordoni & Palagi, 2011).”
BackgroundInfluential
Early effects of gonadal steroids on the neuron number in the medial posterior region and the lateral division of the bed nucleus of the stria terminalis in the rat.
Guillamon, A., Segovia, S., & del Abril, A. (1988) · Brain research. Developmental brain research · doi:10.1016/0165-3806(88)90226-x · Cited by 170 · see citing works
Vasopressin and Aggression in Cross-Fostered California Mice (Peromyscus californicus) and White-Footed Mice (Peromyscus leucopus)
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Disruption of synaptic transmission or clock-gene-product oscillations in circadian pacemaker cells ofDrosophila cause abnormal behavioral rhythms
Kaneko, M. A. N., Park, J. H., Cheng, Y., Hardin, P. E., & Hall, J. C. (2000) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(20000605)43:3 · Cited by 138 · see citing works
Developmental regulation of sex differences in the brain: Can the role of gonadal steroids be redefined?
Pilgrim, C., & Hutchison, J. B. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90267-4 · Cited by 152 · see citing works
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Aste, N., Balthazart, J., Absil, P., Grossmann, R., M�lhbauer, E., Viglietti‐Panzica, C., & Panzica, G. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980629)396:2 · Cited by 147 · see citing works
Social functions of individual vasopressin–oxytocin cell groups in vertebrates: What do we really know?
Kelly, A. M., & Goodson, J. L. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.04.005 · Cited by 141 · see citing works
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Toufexis, D. J., Myers, K. M., & Davis, M. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.06.020 · Cited by 144 · see citing works
The neurophysin-containing innervation of the forebrain of the mouse
Castel, M., & Morris, J. F. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90078-4 · Cited by 143 · see citing works
Sex and species differences in the effects of cohabitation on vasopressin messenger RNA expression in the bed nucleus of the stria terminalis in prairie voles (Microtus ochrogaster) and meadow voles (Microtus pennsylvanicus)
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Sex Differences in Androgen Receptors and Aromatase Activity in Microdissected Regions of the Rat Brain*
ROSELLI, C. E. (1991) · Endocrinology · doi:10.1210/endo-128-3-1310 · Cited by 139 · see citing works
Differential lateral septal vasopressin innervation in aggressive and nonaggressive male mice
Compaan, J. C., Buijs, R. M., Pool, C. W., De Ruiter, A. J. H., & koolhaas, J. M. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90032-7 · Cited by 135 · see citing works
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Axelson, J. F., & van Leeuwen, F. W. (1990) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1990.tb00852.x · Cited by 133 · see citing works
Voles and vasopressin: A review of molecular, cellular, and behavioral studies of pair bonding and paternal behaviors
Wang, Z., Young, L. J., Vries, G. J. D., & Insel, T. R. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)61589-7 · Cited by 132 · see citing works
Comparative neuroanatomy of vasotocin and vasopressin in amphibians and other vertebrates
Moore, F. L., & Lowry, C. A. (1998) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/s0742-8413(98)00014-0 · Cited by 130 · see citing works
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Sex differences in hormonal responses of vasopressin pathways in the rat brain
De Vries, G. J., & Al‐Shamma, H. A. (1990) · Journal of Neurobiology · doi:10.1002/neu.480210503 · Cited by 129 · see citing works
Vasopressin and oxytocin systems in the brain and upper spinal cord of Macaca fascicularis
Caffé, A. R., Van Ryen, P. C., Van Der Woude, T. P., & Van Leeuwen, F. W. (1989) · Journal of Comparative Neurology · doi:10.1002/cne.902870304 · Cited by 128 · see citing works
The Neurobiology of Social Affiliation and Pair Bonding
Carter, C. S., & Keverne, E. B. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00004-8 · Cited by 128 · see citing works
Neurochemical regulation of pair bonding in male prairie voles
Wang, Z., & Aragona, B. J. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.08.024 · Cited by 125 · see citing works
Sex differences in vasopressin neurons in the bed nucleus of the stria terminalis by in situ hybridization
MILLER, M. A., Vician, L. J., Clifton, D. K., & Dorsa, D. M. (1989) · Peptides · doi:10.1016/0196-9781(89)90152-6 · Cited by 126 · see citing works
Sexual differentiation of vasopressin projections of the bed nucleus of the stria terminals and medial amygdaloid nucleus in rats.
Wang, Z., Bullock, N. A., & De Vries, G. J. (1993) · Endocrinology · doi:10.1210/endo.132.6.8504734 · Cited by 123 · see citing works
Decline of vasopressin immunoreactivity and mRNA levels in the bed nucleus of the stria terminalis following castration
Miller, M., DeVries, G., al-Shamma, H., & Dorsa, D. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-08-02881.1992 · Cited by 122 · see citing works
Epigenetic control of vasopressin expression is maintained by steroid hormones in the adult male rat brain
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Aggression and arginine vasopressin immunoreactivity regulation by androgen receptor and estrogen receptor α
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Estrogen receptor‐β in oxytocin and vasopressin neurons of the rat and human hypothalamus: Immunocytochemical and in situ hybridization studies
Hrabovszky, E., Kalló, I., Steinhauser, A., Merchenthaler, I., Coen, C. W., Petersen, S. L., & Liposits, Z. (2004) · Journal of Comparative Neurology · doi:10.1002/cne.20127 · Cited by 118 · see citing works
Organizational effects of testosterone, estradiol, and dihydrotestosterone on vasopressin mRNA expression in the bed nucleus of the stria terminalis
Han, T. M., & De Vries, G. J. (2003) · Journal of Neurobiology · doi:10.1002/neu.10157 · Cited by 116 · see citing works
Sex-dependent regulation of social reward by oxytocin: an inverted U hypothesis
Borland, J. M., Rilling, J. K., Frantz, K. J., & Albers, H. E. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-018-0129-2 · Cited by 116 · see citing works
Oxytocin and vasopressin: genetics and behavioral implications
Caldwell, H. K., & Young, W. S. (2006) · Handbook of Neurochemistry and Molecular Neurobiology · doi:10.1007/978-0-387-30381-9_25 · Cited by 113 · see citing works
Oxytocin and Vasopressin: Genetics and Behavioral Implications
Caldwell, H. K., & Young, W. S. (2006) · Springer eBooks · doi:10.1007/0-387-30395-2_25 · Cited by 113 · see citing works
The Prairie Vole (Microtus ochrogaster): An Animal Model for Behavioral Neuroendocrine Research on Pair Bonding
Aragona, B. J., & Wang, Z. (2004) · ILAR Journal · doi:10.1093/ilar.45.1.35 · Cited by 112 · see citing works
Steroid Dependency of Vasopressin Neurons in the Bed Nucleus of the Stria Terminalis byin SituHybridization*
MILLER, M. A., URBAN, J. H., & DORSA, D. M. (1989) · Endocrinology · doi:10.1210/endo-125-5-2335 · Cited by 134 · see citing works
The Neurobiology of Social Affiliation and Pair Bonding
Carter, C. S., & Keverne, E. B. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50006-8 · Cited by 109 · see citing works
Preoptic AVT Immunoreactive Neurons of a Teleost Fish with Alternative Reproductive Tactics
Foran, C. M., & Bass, A. H. (1998) · General and Comparative Endocrinology · doi:10.1006/gcen.1998.7113 · Cited by 110 · see citing works
Chronic anabolic-androgenic steroid treatment during adolescence increases anterior hypothalamic vasopressin and aggression in intact hamsters
Harrison, R. J., Connor, D. F., Nowak, C., Nash, K. V., & Melloni, R. H. (2000) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(99)00057-8 · Cited by 106 · see citing works
Vasotocinergic innervation of sexually dimorphic medial preoptic nucleus of the male Japanese quail: influence of testosterone
Viglietti‐Panzica, C., Aste, N., Balthazart, J., & Panzica, G. (1994) · Brain Research · doi:10.1016/0006-8993(94)90965-2 · Cited by 105 · see citing works
Seasonal variation in vasopressin innervation in the brain of the European hamster (Cricetus cricetus)
Buijs, R. M., Pévet, P., Masson‐Pévet, M., Pool, C. W., Vries, G. J. D., Canguilheim, B., & VIVIEN‐ROELS, B. (1986) · Brain Research · doi:10.1016/0006-8993(86)90829-2 · Cited by 106 · see citing works
Neuropeptides and male sexual behavior
Dornan, W. A., & Malsbury, C. W. (1989) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(89)80046-6 · Cited by 103 · see citing works
Double duty for sex differences in the brain
De Vries, G. J., & Boyle, P. A. (1998) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00192-7 · Cited by 103 · see citing works
Differential Lateral Septal Vasopressin in Wild-type Rats: Correlation with Aggression
Everts, H. G. J., de Ruiter, A. J. H., & Koolhaas, J. M. (1997) · Hormones and Behavior · doi:10.1006/hbeh.1997.1375 · Cited by 102 · see citing works
Steroid-induced plasticity in the sexually dimorphic vasotocinergic innervation of the avian brain: behavioral implications
Panzica, G., Aste, N., Castagna, C., Viglietti‐Panzica, C., & Balthazart, J. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00118-7 · Cited by 99 · see citing works
Differential Transcriptional Regulation of Rat Vasopressin Gene Expression by Estrogen Receptor α and β**This work was supported by Public Health Service Grant NS20311 and the Alzheimer’s Disease Research Center of the University of Washington, AG-05136. These sequence data have been submitted to the DNA Database of Japan/European Molecular Biology Laboratory/GenBank databases under accession number AF112362.
Shapiro, R. A., Xu, C., & Dorsa, D. M. (2000) · Endocrinology · doi:10.1210/endo.141.11.7796 · Cited by 98 · see citing works
Organization of vasotocin‐immunoreactive cells and fibers in the canary brain
Kiss, J. Z., Voorhuis, T. A. M., van Eekelen, J. A. M., de Kloet, E. R., & de Wied, D. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902630304 · Cited by 97 · see citing works
Epigenetic impacts of endocrine disruptors in the brain
Walker, D. M., & Gore, A. C. (2017) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2016.09.002 · Cited by 94 · see citing works
Sexual dimorphism in the vasotocin system of the bullfrog (Rana catesbeiana)
Boyd, S. K., Tyler, C. J., & Vries, G. J. D. (1992) · The Journal of Comparative Neurology · doi:10.1002/cne.903250213 · Cited by 93 · see citing works
Roles for androgens in mediating the sex differences of neuroendocrine and behavioral stress responses
Zuloaga, D. G., Heck, A., Guzman, R. M. D., & Handa, R. J. (2020) · Biology of Sex Differences · doi:10.1186/s13293-020-00319-2 · Cited by 96 · see citing works
Sexual dimorphism in the vasopressin system: Lack of an altered behavioral phenotype in female V1a receptor knockout mice
Bielsky, I. F., Hu, S.-B., & Young, L. J. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.06.005 · Cited by 91 · see citing works
Estradiol, Progesterone, and Prolactin Regulate Maternal Nest‐Building in Rabbits
González‐Mariscal, G., Melo, Á. I., Jiménez, P., Beyer, C., & Rosenblatt, J. S. (1996) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1996.tb00818.x · Cited by 91 · see citing works
Differential distribution of immunohistochemical markers in the bed nucleus of the stria terminalis in the human brain
Walter, A., Mai, J. K., Lanta, L., & Görcs, T. J. (1991) · Journal of Chemical Neuroanatomy · doi:10.1016/0891-0618(91)90019-9 · Cited by 90 · see citing works
Lesions in the medial posterior region of the BST impair sexual behavior in sexually experienced and inexperienced male rats
Claro, F., Segovia, S., Guillamón, A., & del Abril, A. (1995) · Brain Research Bulletin · doi:10.1016/0361-9230(94)00118-k · Cited by 91 · see citing works
The vasopressin deficient Brattleboro rats: A natural knockout model used in the search for CNS effects of vasopressin
Bohus, B., & de Wied, D. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)61593-9 · Cited by 91 · see citing works
Arginine Vasotocin Injection Increases Probability of Calling in Cricket Frogs, but Causes Call Changes Characteristic of Less Aggressive Males
Marler, C. A., Chu, J., & Wilczynski, W. (1995) · Hormones and Behavior · doi:10.1006/hbeh.1995.1286 · Cited by 92 · see citing works
Increased accumulation of oxytocin messenger ribonucleic acid in the hypothalamus of the female rat: induction by long term estradiol and progesterone administration and subsequent progesterone withdrawal
Crowley, R. S., Insel, T. R., O’Keefe, J. A., Kim, N. B., & Amico, J. A. (1995) · Endocrinology · doi:10.1210/endo.136.1.7828535 · Cited by 89 · see citing works
Steroid hormones and CNS sexual dimorphisms modulate symptom expression in tourette's syndrome
Peterson, B. S., Leckman, J. F., Scahill, L. D., Naftolin, F. N., Keefe, D., Charest, N. J., & Cohen, D. J. (1992) · Psychoneuroendocrinology · doi:10.1016/0306-4530(92)90015-y · Cited by 90 · see citing works
Vasopressinergic modulation of stress responses in the central amygdala of the Roman high-avoidance and low-avoidance rat
Roozendaal, B., Wiersma, A. T., Driscoll, P., Koolhaas, J. M., & Bohus, B. (1992) · Brain Research · doi:10.1016/0006-8993(92)91529-n · Cited by 88 · see citing works
Role of the androgen receptor in the central nervous system
Mhaouty‐Kodja, S. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.08.001 · Cited by 84 · see citing works
Testosterone-sensitive vasotocin-immunoreactive cells and fibers in the canary brain
Voorhuis, T. A. M., Kiss, J. Z., de Kloet, E. R., & de Wied, D. (1988) · Brain Research · doi:10.1016/0006-8993(88)91441-2 · Cited by 85 · see citing works
Histoautoradiographic detection of oxytocin‐ and vasopressin‐binding sites in the telencephalon of the rat
Krémarik, P., Freund‐Mercier, M. J., & Stoeckel, M. E. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903330304 · Cited by 80 · see citing works
Androgen and Estrogen Effects on Vasopressin Messenger RNA Expression in the Medial Amygdaloid Nucleus in Male and Female Rats
Wang, Z., & De Vries, G. J. (1995) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1995.tb00722.x · Cited by 77 · see citing works
Vasopressin cell groups exhibit strongly divergent responses to copulation and male-male interactions in mice
Ho, J. M., Murray, J. H., Demas, G. E., & Goodson, J. L. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.03.021 · Cited by 76 · see citing works
Quantitative mapping reveals age and sex differences in vasopressin, but not oxytocin, immunoreactivity in the rat social behavior neural network
DiBenedictis, B. T., Nussbaum, E. R., Cheung, H. K., & Veenema, A. H. (2017) · Journal of Comparative Neurology · doi:10.1002/cne.24216 · Cited by 74 · see citing works
“LS circuit as well as reduced levels of intermale aggression (Koolhaas, Moor, Hiemstra, & Bohus, 1991; Miller et al., 1992; Szot & Dorsa, 1993; van Leeuwen et al., 1985).”
Background
Sex Differences in Neuronal Morphology Influenced Hormonally throughout Life
Tobet, S. A., & Fox, T. O. (1992) · Handbook of behavioral neurobiology · doi:10.1007/978-1-4899-2453-7_2 · Cited by 74 · see citing works
Vasopressin Localization and Putative Functions in the Brain
Buijs, R. M. (1987) · Springer eBooks · doi:10.1007/978-1-4615-8129-1_2 · Cited by 70 · see citing works
Sexual dimorphism of arg-vasotocin gene expressing neurons in the telencephalon and dorsal diencephalon of the domestic fowl. An immunocytochemical and in situ hybridization study
Jurkevich, A., Barth, S., & Grossmann, R. (1996) · Cell and Tissue Research · doi:10.1007/s004410050732 · Cited by 68 · see citing works
Brain Sexual Dimorphism and Sex Differences in Parental and Other Social Behaviorsa
Vries, G. J. D., & Villalba, C. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51926.x · Cited by 68 · see citing works
Peripheral vasopressin but not oxytocin relates to severity of acute psychosis in women with acutely-ill untreated first-episode psychosis
Rubin, L. H., Carter, C. S., Bishop, J. R., Pournajafi‐Nazarloo, H., Harris, M. S. H., Hill, S. K., Reilly, J. L., & Sweeney, J. A. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.01.019 · Cited by 65 · see citing works
Changes in the Arginine‐Vasopressin Immunoreactive Systems in Male Mice Lacking a Functional Aromatase Gene
Plumari, L., Viglietti‐Panzica, C., Allieri, F., Honda, S., Harada, N., Absil, P., Balthazart, J., & Panzica, G. C. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00866.x · Cited by 66 · see citing works
Testosterone alters the behavioral response of the medial preoptic-anterior hypothalamus to microinjection of arginine vasopressin in the hamster
Albers, H. E., Liou, S. Y., & Ferris, C. F. (1988) · Brain Research · doi:10.1016/0006-8993(88)90244-2 · Cited by 65 · see citing works
Coexistence of vasopressin, neurophysin and noradrenaline immunoreactivity in medium-sized cells of the locus coeruleus and subcoeruleus in the rat
Caffe´, A. R., van Leeuwen, F. W., Buijs, R. M., Vries, G. J. D., & Geffard, M. (1985) · Brain Research · doi:10.1016/0006-8993(85)90260-4 · Cited by 64 · see citing works

Decline of Vasopressin lmmunoreactivity and mRNA Levels in the Bed Nucleus of the Stria Terminalis Following Castration
Miller, M. A., Vries, G. J. D., Al-shamma, H. A., Dorsa, D. M., Miller, M. A., Devries, G. J., & Al-shamma, H. A. (2013)
Sexual differentiation of vasopressin projections of the bed nucleus of the stria terminalis and medial amygdaloid nucleus in rats. Endocrinology 132
Wang, Z., Bullock, N., & Vries, G. J. D. (1993)
Steroid Dependency of Vasopressin Neurons in the Bed Nucleus of the Stria Terminalis byin SituHybridization*
MILLER, M. A., URBAN, J. H., & DORSA, D. M. (1989) · Endocrinology · doi:10.1210/endo-125-5-2335 · Cited by 134 · see citing works
Sexual differentiation of vasopressin projections of the bed nucleus of the stria terminalis and medial amygdaloid nucleus in rats
Vries, G. J. D., Wang, Z. X., & Bullock, N. A. (1993) · ScholarWorks@UMassAmherst (University of Massachusetts Amherst)
The vasopressinergic innervation of the brain in normal and castrated rats
DeVries, G. J., Buijs, R. M., van Leeuwen, F. W., Caffé, A. R., & Swaab, D. F. (1985) · Journal of Comparative Neurology · doi:10.1002/cne.902330206 · Cited by 522 · see citing works

Authors: van Leeuwen, F. W., Caffe, A. R., & Vries, G. J. D.
ORCID: Vries, G.J. de
Venue: Brain Research
Publisher: Elsevier BV
Published: 1985-01
Volume: 325
Issue: 1-2
Pages: 391-394
ISSN: 0006-8993 (ISSN-L)
DOI: 10.1016/0006-8993(85)90348-8
OpenAlex: W2010711792
Cited by: 248
References: 24
Citations by year: 2026: 1 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 6 · 2016: 7 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 2
FWCI: 13.44
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Brain Research (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
Keywords: vasopressin, bed nucleus of the stria terminalis, sex differences, androgens, testosterone, castration, neuroendocrine regulation, rats
MeSH terms: Animals, Diencephalon, Female, Histocytochemistry, Immunochemistry, Limbic System, Male, Rats, Inbred Strains, Sex Characteristics, Testosterone, Vasopressins, Rats

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Vasopressin cells in the bed nucleus of the stria terminalis of the rat: sex differences and the influence of androgens

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