Dorsal striatum responses to reward and punishment: effects of valence and magnitude manipulations
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The goal of this research was to further our understanding of how the striatum responds to the delivery of affective feedback. Previously, we had found that the striatum showed a pattern of sustained activation after presentation of a monetary reward, in contrast to a decrease in the hemodynamic response after a punishment. In this study, we tested whether the activity of the striatum could be modulated by parametric variations in the amount of financial reward or punishment. We used an event-related fMRI design in which participants received large or small monetary rewards or punishments after performance in a gambling task. A parametric ordering of conditions was observed in the dorsal striatum according to both magnitude and valence. In addition, an early response to the presentation of feedback was observed and replicated in a second experiment with increased temporal resolution. This study further implicates the dorsal striatum as an integral component of a reward circuitry responsible for the control of motivated behavior, serving to code for such feedback properties as valence and magnitude.
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The IPS and putamen are associated with response planning, oculomotor control, reward prediction, and outcome.
“The IPS and putamen have both been associated with response planning, oculomotor control (Everling & Munoz, 2000), reward prediction (Peck et al., 2009) and outcome (Delgado et al., 2003).”
From Developmental changes in brain function underlying the influence of reward processing on inhibitory control (2011) · cites this paper as Delgado et al., 2003
In the context of uncertainty (e.g., gambling task), the dorsal striatum responds to valence (reward or loss) and magnitude of outcomes, showing strongest activation to large monetary rewards and weakest activation to large monetary losses.
“previous studies have shown that in the context of uncertainty (e.g., gambling task) also the dorsal striatum responds to valence (reward or loss) and magnitude of outcomes, showing strongest activation to large monetary rewards, and weakest activation to large monetary losses (Delgado et al., 2003).”
From Testosterone levels correspond with increased ventral striatum activation in response to monetary rewards in adolescents (2011) · cites this paper as Delgado et al., 2003
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Prospect Theory: An Analysis of Decision under Risk
Kahneman, D., & Tversky, A. (1979) · Econometrica · doi:10.2307/1914185 · Cited by 48,524 · see citing works
Prospect theory: An analysis of decision under risk
Kahneman, D. J., & Tversky, A. (1988) · Cambridge University Press eBooks · doi:10.1017/cbo9780511609220.014 · Cited by 32,700 · see citing works
The Framing of Decisions and the Psychology of Choice
Tversky, A., & Kahneman, D. (1981) · Science · doi:10.1126/science.7455683 · Cited by 17,604 · see citing works
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913 · see citing works
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444 · see citing works
Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.
Kwong, K. K., Belliveau, J. W., Chesler, D. A., Goldberg, I. E., Weisskoff, R. M., Poncelet, B. P., Kennedy, D. N., Hoppel, B. E., Cohen, M. S., & Turner, R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5675 · Cited by 4,212 · see citing works
Emotion, Decision Making and the Orbitofrontal Cortex
Bechara, A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.295 · Cited by 3,589 · see citing works
Forman, S. D., Cohen, J. D., Fitzgerald, M., Eddy, W. F., Mintun, M. A., & Noll, D. C. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910330508 · Cited by 3,202 · see citing works
(1987) · American Journal of Psychiatry · doi:10.1176/ajp.144.9.1184 · Cited by 2,948 · see citing works
Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-j0002.2001 · Cited by 2,244 · see citing works
Abstract reward and punishment representations in the human orbitofrontal cortex
O'Doherty, J., Kringelbach, M. L., Rolls, E. T., Hornak, J., & Andrews, C. (2001) · Nature Neuroscience · doi:10.1038/82959 · Cited by 2,003 · see citing works
Rapid Automated Algorithm for Aligning and Reslicing PET Images
Woods, R. P., Cherry, S. R., & Mazziotta, J. C. (1992) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199207000-00024 · Cited by 1,932 · see citing works
Temporal dynamics of brain activation during a working memory task
Cohen, J. D., Perlstein, W. M., Braver, T. S., Nystrom, L. E., Noll, D. C., Jonides, J., & Smith, E. E. (1997) · Nature · doi:10.1038/386604a0 · Cited by 1,876 · see citing works
MRI-PET Registration with Automated Algorithm
Woods, R. P., Mazziotta, J. C., & Cherry, A. S. R. (1993) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199307000-00004 · Cited by 1,636 · see citing works
The Orbitofrontal Cortex and Reward
Rolls, E. T. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.284 · Cited by 1,595 · see citing works
FMRI visualization of brain activity during a monetary incentive delay task
Knutson, B., Westdorp, A., Kaiser, E., & Hommer, D. (2000) · NeuroImage · doi:10.1006/nimg.2000.0593 · Cited by 1,414 · see citing works
Functional imaging of neural responses to expectancy and experience of monetary gains and losses
Breiter, H. C., Aharon, I., Kahneman, D., Dale, A., & Shizgal, P. (2001) · Neuron · doi:10.1016/s0896-6273(01)00303-8 · Cited by 1,404 · see citing works
Rolls, E. T. (1998) · doi:10.1093/oso/9780198524649.001.0001 · Cited by 1,314 · see citing works
Multiple reward signals in the brain
Schultz, W. (2000) · Nature Reviews Neuroscience · doi:10.1038/35044563 · Cited by 1,303 · see citing works
Dissociation of reward anticipation and outcome with event-related fMRI
Knutson, B., Fong, G. W., Adams, C. M., Varner, J. L., & Hommer, D. (2001) · Neuroreport · doi:10.1097/00001756-200112040-00016 · Cited by 1,300 · see citing works
Evidence for striatal dopamine release during a video game
Koepp, M. J., Gunn, R. N., Lawrence, A. D., Cunningham, V. J., Dagher, A., Jones, T., Brooks, D. J., Bench, C. J., & Grasby, P. M. (1998) · Nature · doi:10.1038/30498 · Cited by 1,279 · see citing works
The Framing of Decisions and the Psychology of Choice
Tversky, A., & Kahneman, D. J. (1985) · Springer eBooks · doi:10.1007/978-1-4613-2391-4_2 · Cited by 1,252 · see citing works
The Variability of Human, BOLD Hemodynamic Responses
Aguirre, G. K., Zarahn, E., & D’Esposito, M. (1998) · NeuroImage · doi:10.1006/nimg.1998.0369 · Cited by 1,224 · see citing works
Neurobehavioural mechanisms of reward and motivation
Robbins, T. W., & Everitt, B. J. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80077-8 · Cited by 1,187 · see citing works
Tracking the Hemodynamic Responses to Reward and Punishment in the Striatum
Delgado, M. R., Nystrom, L. E., Fissell, C., Noll, D. C., & Fiez, J. A. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.6.3072 · Cited by 1,116 · see citing works
Self-citationBeautiful Faces Have Variable Reward Value
Aharon, I., Etcoff, N., Ariely, D., Chabris, C. F., O'Connor, E., & Breiter, H. C. (2001) · Neuron · doi:10.1016/s0896-6273(01)00491-3 · Cited by 1,087 · see citing works
Transient and sustained activity in a distributed neural system for human working memory
Courtney, S. M., Ungerleider, L. G., Keil, K., & Haxby, J. V. (1997) · Nature · doi:10.1038/386608a0 · Cited by 960 · see citing works
Quantitative Variation of Incentive and Performance in the White Rat
Crespi, L. P. (1942) · The American Journal of Psychology · doi:10.2307/1417120 · Cited by 894 · see citing works
Rogers, R. D., Owen, A. M., Middleton, H. C., Williams, E., Pickard, J. D., Sahakian, B. J., & Robbins, T. W. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-20-09029.1999 · Cited by 865 · see citing works
Neuronal activity in monkey ventral striatum related to the expectation of reward
Schultz, W., Apicella, P., Scarnati, E., & Ljungberg, T. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-12-04595.1992 · Cited by 744 · see citing works
Dissociable Neural Responses in Human Reward Systems
Elliott, R., Friston, K. J., & Dolan, R. J. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-16-06159.2000 · Cited by 740 · see citing works
Predictability modulates human brain response to reward
Berns, G. S., McClure, S. M., Pagnoni, G., & Montague, P. R. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02793.2001 · Cited by 711 · see citing works
Associative processes in addiction and reward. The role of amygdala-ventral striatal subsystems
EVERITT, B. J., PARKINSON, J. A., OLMSTEAD, M. C., ARROYO, M., ROBLEDO, P., & ROBBINS, T. W. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09280.x · Cited by 708 · see citing works
Convergence and segregation of ventral striatal inputs and outputs
GROENEWEGEN, H. J., WRIGHT, C. I., BEIJER, A. V. J., & VOORN, P. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09260.x · Cited by 684 · see citing works
Basal Ganglia Output and Cognition: Evidence from Anatomical, Behavioral, and Clinical Studies
Middleton, F. A., & Strick, P. L. (2000) · Brain and Cognition · doi:10.1006/brcg.1999.1099 · Cited by 662 · see citing works
Expectation of reward modulates cognitive signals in the basal ganglia
Kawagoe, R., Takikawa, Y., & Hikosaka, O. (1998) · Nature Neuroscience · doi:10.1038/1625 · Cited by 632 · see citing works
Drug abusers show impaired performance in a laboratory test of decision making
Grant, S. (2000) · Neuropsychologia · doi:10.1016/s0028-3932(99)00158-x · Cited by 625 · see citing works
Buckner, R. L., Goodman, J. M., Burock, M. A., Rotte, M., Koutstaal, W., Schacter, D. L., Rosen, B. R., & Dale, A. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80456-0 · Cited by 622 · see citing works
The orbital and medial prefrontal circuit through the primate basal ganglia
Haber, S., Kunishio, K., Mizobuchi, M., & Lynd-Balta, E. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-07-04851.1995 · Cited by 605 · see citing works
Aosaki, T., Tsubokawa, H., Ishida, A., Watanabe, K., Graybiel, A. M., & Kimura, M. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-06-03969.1994 · Cited by 600 · see citing works
Hikosaka, O., Sakamoto, M., & Usui, S. (1989) · Journal of Neurophysiology · doi:10.1152/jn.1989.61.4.814 · Cited by 579 · see citing works
The neurobiology of drug addiction
Koob, G. F., & Nestler, E. J. (1997) · Journal of Neuropsychiatry · doi:10.1176/jnp.9.3.482 · Cited by 572 · see citing works
Ito, R., Dalley, J. W., Robbins, T. W., & Everitt, B. J. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-14-06247.2002 · Cited by 463 · see citing works
Volkow, N. D., Wang, G., Fowler, J. S., Logan, J., Jayne, M., Franceschi, D., Wong, C., Gatley, S. J., Gifford, A. N., Ding, Y., et al. (2002) · Synapse · doi:10.1002/syn.10075 · Cited by 452 · see citing works
Activity in human ventral striatum locked to errors of reward prediction
Pagnoni, G., Zink, C. F., Montague, P. R., & Berns, G. S. (2002) · Nature Neuroscience · doi:10.1038/nn802 · Cited by 451 · see citing works
Leon, M. I., & Shadlen, M. N. (1999) · Neuron · doi:10.1016/s0896-6273(00)80854-5 · Cited by 449 · see citing works
A neural correlate of response bias in monkey caudate nucleus
Lauwereyns, J., Watanabe, K., Coe, B. C., & Hikosaka, O. (2002) · Nature · doi:10.1038/nature00892 · Cited by 415 · see citing works
Influence of Reward Expectation on Behavior-Related Neuronal Activity in Primate Striatum
Hollerman, J. R., Tremblay, L., & Schultz, W. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.2.947 · Cited by 380 · see citing works
Responses to reward in monkey dorsal and ventral striatum
Apicella, P., Ljungberg, T., Scarnati, E., & Schultz, W. (1991) · Experimental Brain Research · doi:10.1007/bf00231732 · Cited by 369 · see citing works
Dynamic mapping of the human visual cortex by high-speed magnetic resonance imaging.
Blamire, A. M., Ogawa, S., Uǧurbil, K., Rothman, D. L., McCarthy, G., Ellermann, J., Hyder, F., Rattner, Z., & Shulman, R. G. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.11069 · Cited by 368 · see citing works
Functions of dopamine in the dorsal and ventral striatum
Robbins, T. W., & Everitt, B. J. (1992) · Seminars in Neuroscience · doi:10.1016/1044-5765(92)90010-y · Cited by 348 · see citing works
The Role of the Striatopallidal and Extended Amygdala Systems in Drug Addiction
Koob, G. F. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09282.x · Cited by 322 · see citing works
Reward prediction in primate basal ganglia and frontal cortex
Schultz, W., Tremblay, L., & Hollerman, J. R. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00071-9 · Cited by 318 · see citing works
Neuronal activity in monkey striatum related to the expectation of predictable environmental events
Apicella, P., Scarnati, E., Ljungberg, T., & Schultz, W. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.68.3.945 · Cited by 305 · see citing works
Influence of Expectation of Different Rewards on Behavior-Related Neuronal Activity in the Striatum
Hassani, O. K., Cromwell, H. C., & Schultz, W. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.6.2477 · Cited by 257 · see citing works
Spiral K‐space MR imaging of cortical activation
Noll, D. C., Cohen, J. D., Meyer, C. H., & Schneider, W. (1995) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1880050112 · Cited by 254 · see citing works
DI CHIARA, G., TANDA, G., BASSAREO, V., PONTIERI, F., ACQUAS, E., FENU, S., CADONI, C., & CARBONI, E. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09283.x · Cited by 242 · see citing works
Functional Magnetic Resonance Imaging of Brain Reward Circuitry in the Human
BREITER, H. C., & Rosen, B. R. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09287.x · Cited by 231 · see citing works
Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior
Hollerman, J. R., Tremblay, L., & Schultz, W. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)26015-9 · Cited by 219 · see citing works
Shidara, M., Aigner, T. G., & Richmond, B. J. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-07-02613.1998 · Cited by 205 · see citing works
Elliott, R., Sahakian, B. J., Michael, A., Paykel, E. S., & Dolan, R. J. (1998) · Psychological Medicine · doi:10.1017/s0033291798006709 · Cited by 168 · see citing works
Feature-Based Anticipation of Cues that Predict Reward in Monkey Caudate Nucleus
Lauwereyns, J., Takikawa, Y., Kawagoe, R., Kobayashi, S., Koizumi, M., Coe, B. C., Sakagami, M., & Hikosaka, O. (2002) · Neuron · doi:10.1016/s0896-6273(02)00571-8 · Cited by 123 · see citing works
Lin, J. C., Cai, L., & Cepko, C. L. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-01-00159.2001 · Cited by 116 · see citing works
The PsyScope experiment-building system
MacWhinney, B., Provost, J., & Cohen, J. (1997) · Spatial Vision · doi:10.1163/156856897x00113 · Cited by 107 · see citing works
Pure Topographical Disorientation —The Anatomical Basis of Landmark Agnosia
Takahashi, N., & Kawamura, M. (2002) · Cortex · doi:10.1016/s0010-9452(08)70039-x · Cited by 107 · see citing works
Salinas, J. A., Packard, M., & McGaugh, J. D. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90162-j · Cited by 77 · see citing works
McGINTY, J. F. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09257.x · Cited by 77 · see citing works
The variability of human BOLD hemodynamic responses
Aguirre, G., Zarahn, E., & D’Esposito, M. (1998) · NeuroImage · doi:10.1016/s1053-8119(18)31407-1 · Cited by 72 · see citing works
Brown, V. J., & Bowman, E. M. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb01046.x · Cited by 67 · see citing works
Salinas, J. A., & White, N. M. (1998) · Behavioral Neuroscience · doi:10.1037//0735-7044.112.4.812 · Cited by 51 · see citing works
Salinas, J. A., & White, N. M. (1998) · Behavioral Neuroscience · doi:10.1037/0735-7044.112.4.812 · Cited by 41 · see citing works
The Temporal Resolution of Functional MRI
Bandettini, P. A. (2000) · Medical radiology · doi:10.1007/978-3-642-58716-0_19 · Cited by 34 · see citing works
Functional Neuroimaging Methods: PET and fMRI
Logan, J. M., & Buckner, R. L. (2001) · Cited by 26 · see citing works
Flagged first, then by citations
2 of the 76 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Crespi, L. P. (1942). Quantitative variation of reinforcement and level of performance. American Journal of Psychology, 55, 467-517.
- Talairach, J., & Tournoux, P. (1988). Co-planar stereotaxic atlas of the human brain: An approach to medical cerebral imaging. New York: Thieme Medical Publishers.
Cited by
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The reward circuit: linking primate anatomy and human imaging
Haber, S. N., & Knutson, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.129 · Cited by 3,718 · see citing works
The role of the basal ganglia in habit formation
Yin, H. H., & Knowlton, B. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1919 · Cited by 2,402 · see citing works
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
O'Doherty, J., Dayan, P., Schultz, J., Deichmann, R., Friston, K., & Dolan, R. J. (2004) · Science · doi:10.1126/science.1094285 · Cited by 2,088 · see citing works
By Carrot or by Stick: Cognitive Reinforcement Learning in Parkinsonism
Frank, M. J., Seeberger, L. C., & O'Reilly, R. C. (2004) · Science · doi:10.1126/science.1102941 · Cited by 1,964 · see citing works
The Neural Basis of Altruistic Punishment
de Quervain, D. J.-F., Fischbacher, U., Treyer, V., Schellhammer, M., Schnyder, U., Buck, A., & Fehr, E. (2004) · Science · doi:10.1126/science.1100735 · Cited by 1,768 · see citing works
The neural basis of loss aversion in decision-making under risk
Tom, S. M., Fox, C. R., Trepel, C., & Poldrack, R. A. (2007) · Science · doi:10.1126/science.1134239 · Cited by 1,733 · see citing works
Pizzagalli, D. A., Holmes, A. J., Dillon, D. G., Goetz, E. L., Birk, J. L., Bogdan, R., Dougherty, D. D., Iosifescu, D. V., Rauch, S. L., & Fava, M. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08081201 · Cited by 1,232 · see citing works
The Psychology and Neuroscience of Curiosity
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Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love
Aron, A., Fisher, H., Mashek, D. J., Strong, G., Li, H., & Brown, L. L. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00838.2004 · Cited by 963 · see citing works
Independent Coding of Reward Magnitude and Valence in the Human Brain
Yeung, N., & Sanfey, A. G. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4537-03.2004 · Cited by 933 · see citing works
Liu, X., Hairston, J., Schrier, M., & Fan, J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.12.012 · Cited by 916 · see citing works
Kang, M. J., Hsu, M., Krajbich, I. M., Loewenstein, G., McClure, S. M., Wang, J. T.-Y., & Camerer, C. F. (2009) · Psychological Science · doi:10.1111/j.1467-9280.2009.02402.x · Cited by 882 · see citing works
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Shulman, E. P., Smith, A. R., Silva, K., Icenogle, G., Duell, N., Chein, J., & Steinberg, L. (2016) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.12.010 · Cited by 867 · see citing works
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DELGADO, M. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.002 · Cited by 736 · see citing works
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Nieuwenhuis, S., Holroyd, C. B., Mol, N., & Coles, M. G. H. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.05.003 · Cited by 557 · see citing works
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Neural Representation of Subjective Value Under Risk and Ambiguity
Levy, I., Snell, J., Nelson, A. J., Rustichini, A., & Glimcher, P. W. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00853.2009 · Cited by 491 · see citing works
Gujar, N., Yoo, S.-S., Hu, P., & Walker, M. P. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3220-10.2011 · Cited by 491 · see citing works
Reward Value Coding Distinct From Risk Attitude-Related Uncertainty Coding in Human Reward Systems
Tobler, P. N., O'Doherty, J. P., Dolan, R. J., & Schultz, W. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00745.2006 · Cited by 472 · see citing works
Neuroanatomical correlates of aesthetic preference for paintings
Vartanian, O. A., & Goel, V. (2004) · Neuroreport · doi:10.1097/00001756-200404090-00032 · Cited by 470 · see citing works
Motivational influences on cognitive control: Behavior, brain activation, and individual differences
Locke, H., & Braver, T. S. (2008) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.8.1.99 · Cited by 450 · see citing works
Self-citationAnatomical insights into the interaction of emotion and cognition in the prefrontal cortex
Ray, R. D., & Zald, D. H. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.08.005 · Cited by 446 · see citing works
Neural correlates of long-term intense romantic love
Acevedo, B. P., Aron, A., Fisher, H. E., & Brown, L. L. (2012) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq092 · Cited by 441 · see citing works
“…activation of dopamine-rich sites, such as the VTA and caudate, are evoked in response to rewards such as food (Hare et al., 2008), monetary gains (Delgado et al., 2003; D’Ardenne et al., 2008; Carter et al., 2009), cocaine and alcohol (Heinz et al., 2004; Risinger et al., 2005) and overall…”
BackgroundResultProspect theory on the brain? Toward a cognitive neuroscience of decision under risk
Trepel, C., Fox, C. R., & Poldrack, R. A. (2005) · Cognitive Brain Research · doi:10.1016/j.cogbrainres.2005.01.016 · Cited by 400 · see citing works
Having a word with yourself: neural correlates of self-criticism and self-reassurance.
Longe, O., Maratos, F. A., Gilbert, P., Evans, G., Volker, F., Rockliff, H., & Rippon, G. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.019 · Cited by 403 · see citing works
Immaturities in reward processing and its influence on inhibitory control in adolescence.
Geier, C. F., Terwilliger, R., Teslovich, T., Velanova, K., & Luna, B. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp225 · Cited by 396 · see citing works
The brain on art: intense aesthetic experience activates the default mode network
Vessel, E. A., Starr, G. G., & Rubin, N. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00066 · Cited by 392 · see citing works
Context dependence of the event‐related brain potential associated with reward and punishment
Holroyd, C. B., Larsen, J. T., & Cohen, J. D. (2004) · Psychophysiology · doi:10.1111/j.1469-8986.2004.00152.x · Cited by 376 · see citing works
Venkatraman, V., Chuah, Y. L., Huettel, S. A., & Chee, M. W. (2007) · SLEEP · doi:10.1093/sleep/30.5.603 · Cited by 359 · see citing works
Event-related potential studies of outcome processing and feedback-guided learning
San Martín, R. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00304 · Cited by 354 · see citing works
An fMRI study of reward-related probability learning
Delgado, M. R., Miller, M. M., Inati, S., & Phelps, E. A. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.10.002 · Cited by 337 · see citing works
Self-citationDiekhof, E. K., Kaps, L., Falkai, P., & Gruber, O. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.02.007 · Cited by 332 · see citing works
Neural systems of positive affect: relevance to understanding child and adolescent depression?
FORBES, E. E., & DAHL, R. E. (2005) · Development and Psychopathology · doi:10.1017/s095457940505039x · Cited by 318 · see citing works
Reward‐related decision‐making in pediatric major depressive disorder: an fMRI study
Forbes, E. E., Christopher May, J., Siegle, G. J., Ladouceur, C. D., Ryan, N. D., Carter, C. S., Birmaher, B., Axelson, D. A., & Dahl, R. E. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01673.x · Cited by 299 · see citing works
Cinzia, D. D., & D, V. G. M. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.09.001 · Cited by 291 · see citing works
Activity in human reward-sensitive brain areas is strongly context dependent
Nieuwenhuis, S., Heslenfeld, D. J., Alting von Geusau, N. J., Mars, R. B., Holroyd, C. B., & Yeung, N. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.12.043 · Cited by 289 · see citing works
Decoding the neural substrates of reward-related decision making with functional MRI
Hampton, A. N., & O’Doherty, J. P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606297104 · Cited by 279 · see citing works
Embedding reward signals into perception and cognition
Pessoa, L. (2010) · Frontiers in Neuroscience · doi:10.3389/fnins.2010.00017 · Cited by 279 · see citing works
Plichta, M. M., Vasic, N., Wolf, R. C., Lesch, K.-P., Brummer, D., Jacob, C., Fallgatter, A. J., & Grön, G. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.07.008 · Cited by 272 · see citing works
Neural activity predicts attitude change in cognitive dissonance
van Veen, V., Krug, M. K., Schooler, J. W., & Carter, C. S. (2009) · Nature Neuroscience · doi:10.1038/nn.2413 · Cited by 271 · see citing works
How Choice Reveals and Shapes Expected Hedonic Outcome
Sharot, T., Martino, B. D., & Dolan, R. J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4972-08.2009 · Cited by 254 · see citing works
Motivation-dependent responses in the human caudate nucleus.
Delgado, M. R. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh062 · Cited by 246 · see citing works
Self-citationBeyond revenge: Neural and genetic bases of altruistic punishment
Strobel, A., Zimmermann, J., Schmitz, A., Reuter, M., Lis, S., Windmann, S., & Kirsch, P. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.07.051 · Cited by 243 · see citing works
Liu, X., Powell, D. K., Wang, H., Gold, B. T., Corbly, C. R., & Joseph, J. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.5227-06.2007 · Cited by 236 · see citing works
Dopamine Transmission in the Human Striatum during Monetary Reward Tasks
Zald, D. H., Boileau, I., El-Dearedy, W., Gunn, R., McGlone, F., Dichter, G. S., & Dagher, A. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4643-03.2004 · Cited by 238 · see citing works
Frank, G. K., Shott, M. E., Hagman, J. O., & Mittal, V. A. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12101294 · Cited by 237 · see citing works
Neural systems underlying approach and avoidance in anxiety disorders
Robin L., A., & Martin, P. P. (2010) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2010.12.4/raupperle · Cited by 227 · see citing works
The maturation of incentive processing and cognitive control
Geier, C., & Luna, B. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.01.021 · Cited by 225 · see citing works
Jarbo, K., & Verstynen, T. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2636-14.2015 · Cited by 221 · see citing works
Guitart-Masip, M., Fuentemilla, L., Bach, D. R., Huys, Q. J. M., Dayan, P., Dolan, R. J., & Duzel, E. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.6376-10.2011 · Cited by 216 · see citing works
Instructional control of reinforcement learning: A behavioral and neurocomputational investigation
Doll, B. B., Jacobs, W. J., Sanfey, A. G., & Frank, M. J. (2009) · Brain Research · doi:10.1016/j.brainres.2009.07.007 · Cited by 216 · see citing works
Kang, M. J., Hsu, M., Krajbich, I. M., Loewenstein, G. F., McClure, S. M., Wang, J. T., & Camerer, C. (2008) · SSRN Electronic Journal · doi:10.2139/ssrn.1308286 · Cited by 214 · see citing works
Striatal functional alteration in adolescents characterized by early childhood behavioral inhibition
Guyer, A. E., Nelson, E. E., Perez-Edgar, K., Hardin, M. G., Roberson-Nay, R., Monk, C. S., Bjork, J. M., Henderson, H. A., Pine, D. S., Fox, N. A., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0666-06.2006 · Cited by 211 · see citing works
Brain mechanisms of persuasion: how ‘expert power’ modulates memory and attitudes
Klucharev, V., Smidts, A., & Fernández, G. (2008) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsn022 · Cited by 210 · see citing works
The role of ventral frontostriatal circuitry in reward-based learning in humans.
Galvan, A., Hare, T. A., Davidson, M., Spicer, J., Glover, G., & Casey, B. J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2431-05.2005 · Cited by 207 · see citing works
The role of the basal ganglia in learning and memory: Insight from Parkinson’s disease
Foerde, K., & Daphna Shohamy, A. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.08.006 · Cited by 206 · see citing works
Common and distinct neural correlates of personal and vicarious reward: A quantitative meta-analysis
Morelli, S. A., Sacchet, M. D., & Zaki, J. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.12.056 · Cited by 205 · see citing works
Differential Effect of Reward and Punishment on Procedural Learning
Wächter, T., Lungu, O., Liu, T., Willingham, D. T., & Ashe, J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4132-08.2009 · Cited by 204 · see citing works
Op de Macks, Z. A., Moor, B. G., Overgaauw, S., Güroğlu, B., Dahl, R. E., & Crone, E. A. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.06.003 · Cited by 203 · see citing works
Padmanabhan, A., Geier, C. F., Ordaz, S. J., Teslovich, T., & Luna, B. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.06.004 · Cited by 202 · see citing works
Performance Feedback Drives Caudate Activation in a Phonological Learning Task
Tricomi, E. M., Delgado, M. R., McCandliss, B. D., McClelland, J. L., & Fiez, J. A. (2006) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2006.18.6.1029 · Cited by 196 · see citing works
Self-citationModulation of the brain activity in outcome evaluation by interpersonal relationship: An ERP study
Leng, Y., & Zhou, X. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.10.002 · Cited by 199 · see citing works
May, J. C., Delgado, M. R., Dahl, R. E., Stenger, V. A., Ryan, N. D., Fiez, J. A., & Carter, C. S. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.008 · Cited by 193 · see citing works
Self-citationRisk-dependent reward value signal in human prefrontal cortex
Tobler, P. N., Christopoulos, G. I., O’Doherty, J. P., Dolan, R. J., & Schultz, W. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809599106 · Cited by 180 · see citing works
Reward Processing and Risk for Depression Across Development
Luking, K. R., Pagliaccio, D., Luby, J. L., & Barch, D. M. (2016) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2016.04.002 · Cited by 183 · see citing works
The neural basis of academic achievement motivation
Mizuno, K., Tanaka, M., Ishii, A., Tanabe, H. C., Onoe, H., Sadato, N., & Watanabe, Y. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.04.253 · Cited by 182 · see citing works
Andrews, M. M., Meda, S. A., Thomas, A. D., Potenza, M. N., Krystal, J. H., Worhunsky, P., Stevens, M. C., O'Malley, S., Book, G. A., Reynolds, B., et al. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.049 · Cited by 181 · see citing works
Understanding Overbidding: Using the Neural Circuitry of Reward to Design Economic Auctions
Delgado, M. R., Schotter, A., Ozbay, E. Y., & Phelps, E. A. (2008) · Science · doi:10.1126/science.1158860 · Cited by 180 · see citing works
Self-citationSocial and monetary reward processing in autism spectrum disorders
Delmonte, S., Balsters, J. H., McGrath, J., Fitzgerald, J., Brennan, S., Fagan, A. J., & Gallagher, L. (2012) · Molecular Autism · doi:10.1186/2040-2392-3-7 · Cited by 180 · see citing works
Neural Correlates of Forward Planning in a Spatial Decision Task in Humans
Simon, D. A., & Daw, N. D. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4647-10.2011 · Cited by 181 · see citing works
The mentalizing network orchestrates the impact of parochial altruism on social norm enforcement
Baumgärtner, T., Götte, L., Gügler, R., & Fehr, E. (2011) · Human Brain Mapping · doi:10.1002/hbm.21298 · Cited by 182 · see citing works
Neuroanatomic Correlates of Psychopathologic Components of Major Depressive Disorder
Milak, M. S., Parsey, R. V., Keilp, J. G., Oquendo, M. A., Malone, K. M., & Mann, J. J. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.4.397 · Cited by 177 · see citing works
Acute Stress Influences Neural Circuits of Reward Processing
Porcelli, A. J., Lewis, A. H., & Delgado, M. R. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00157 · Cited by 173 · see citing works
Self-citationThe Neurobiology of Reference-Dependent Value Computation
De Martino, B., Kumaran, D., Holt, B., & Dolan, R. J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4832-08.2009 · Cited by 174 · see citing works
Barrett, S. P., Boileau, I., Okker, J., Pihl, R. O., & Dagher, A. (2004) · Synapse · doi:10.1002/syn.20066 · Cited by 172 · see citing works
Human striatal activation reflects degree of stimulus saliency
Zink, C. F., Pagnoni, G., Chappelow, J., Martin-Skurski, M. E., & Berns, G. S. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.08.006 · Cited by 169 · see citing works
From recurrent choice to skill learning: A reinforcement-learning model.
Fu, W., & Anderson, J. R. (2006) · Journal of Experimental Psychology General · doi:10.1037/0096-3445.135.2.184 · Cited by 165 · see citing works
Tit-for-tat: The neural basis of reactive aggression
Krämer, U. M., Jansma, H., Tempelmann, C., & Münte, T. F. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.07.029 · Cited by 166 · see citing works
Striatal functional alteration during incentive anticipation in pediatric anxiety disorders
Guyer, A. E., Choate, V. R., Detloff, A., Benson, B., Nelson, E. E., Perez-Edgar, K., Fox, N. A., Pine, D. S., & Ernst, M. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11010006 · Cited by 165 · see citing works
Elman, I., Lowen, S., Frederick, B. B., Chi, W., Becerra, L., & Pitman, R. K. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.06.006 · Cited by 165 · see citing works
REMIJNSE, P., NIELEN, M., UYLINGS, H., & VELTMAN, D. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.02.009 · Cited by 163 · see citing works
Krawczyk, D. C., Gazzaley, A., & D'Esposito, M. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.052 · Cited by 156 · see citing works
Satterthwaite, T. D., Green, L., Myerson, J., Parker, J. B., Ramaratnam, M., & Buckner, R. L. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.04.066 · Cited by 153 · see citing works
Age differences in the impact of peers on adolescents’ and adults’ neural response to reward
Smith, A. R., Steinberg, L., Strang, N., & Chein, J. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.08.010 · Cited by 147 · see citing works
Effects of Direct Social Experience on Trust Decisions and Neural Reward Circuitry
Fareri, D. S., Chang, L. J., & Delgado, M. R. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00148 · Cited by 147 · see citing works
Self-citationAnderson, J. R., Fincham, J. M., Qin, Y., & Stocco, A. (2008) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2008.01.006 · Cited by 147 · see citing works
Functional connectivity of reward processing in the brain
Camara, E. (2008) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.019.2008 · Cited by 141 · see citing works
Reward-related processing in the human brain: developmental considerations
Fareri, D. S., Martin, L. N., & Delgado, M. R. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000576 · Cited by 141 · see citing works
Self-citationDynamics of aesthetic experience are reflected in the default-mode network
Belfi, A. M., Vessel, E. A., Brielmann, A. A., Isik, A. I., Chatterjee, A. K., Leder, H., Pelli, D. G., & Starr, G. G. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.12.017 · Cited by 137 · see citing works
From Bad to Worse: Striatal Coding of the Relative Value of Painful Decisions
Brooks, A. M., Pammi, V. S. C., NOUSSAIR, C. N., Capra, C. M., Engelmann, J. B., & Berns, G. S. (2010) · Frontiers in Neuroscience · doi:10.3389/fnins.2010.00176 · Cited by 133 · see citing works
- Authors
- DELGADO, M. R., LOCKE, H. M., STENGER, V. A., & FIEZ, J. A.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- DELGADO, M. R.
- Venue
- Cognitive, Affective, & Behavioral Neuroscience
- Published
- 2003-03-01
- Volume
- 3
- Issue
- 1
- Pages
- 27-38
- ISSN
- 1530-7026 (ISSN-L)
- 1531-135X
- OpenAlex
- W2128577709
- Cited by
- 431
- References
- 76
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 9 · 2023: 11 · 2022: 11 · 2021: 15 · 2020: 15 · 2019: 20 · 2018: 22 · 2017: 12 · 2016: 17 · 2015: 17 · 2014: 26 · 2013: 35 · 2012: 19
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cognitive Affective & Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation (9720350)
- National Institutes of Health
- National Institute on Drug Abuse (R01DA14103, R01DA014103)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- dorsal striatum, reward, punishment, emotional feedback, valence, reward magnitude, monetary rewards, gambling task, parametric modulation, motivated behavior, reward systems, hemodynamic response
- MeSH terms
- Adult, Affect, Analysis of Variance, Brain Mapping, Caudate Nucleus, Cerebral Cortex, Corpus Striatum, Evoked Potentials, Female, Humans, Magnetic Resonance Imaging, Male, Motivation, Punishment, Reinforcement, Psychology, Reward, Time Factors, Feedback, Psychological
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