Roles of tau protein in health and disease

Guo, Tong, Noble, Wendy, Hanger, Diane P.·2017·Acta Neuropathologica

Cites (550)

Items 201–400 of 550

  1. Inhibition of Calpain Cleavage of Huntingtin Reduces Toxicity
    Juliette Gafni, Evan Hermel, Jessica E. Young, Cheryl Lea Wellington, Michael R. Hayden, Lisa Ellerby · 2004 · Journal of Biological Chemistry
  2. Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation
    Jeganathan, Sadasivam, Hascher, Antje, Chinnathambi, Subashchandrabose, Biernat, Jacek, Mandelkow, Eva-Maria, Mandelkow, Eckhard · 2008 · Journal of Biological Chemistry
  3. Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
    Tracy, Tara E., Sohn, Peter Dongmin, Minami, S. Sakura, Wang, Chao, Min, Sang-Won, Li, Yaqiao, Zhou, Yungui, Le, David, Lo, Iris, Ponnusamy, Ravikumar et al. · 2016 · Neuron
  4. Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration
    Alan Michael Pittman, A J Myers, Patrick M. Abou‐Sleiman, Hon‐Chung Fung, M Kaleem, Lauren Marlowe, Jaime Duckworth, Doris G. Leung, David R. Williams, Linda Kilford et al. · 2005 · Journal of Medical Genetics
  5. Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies
    Wenjie Luo, Fei Dou, Anna Rodina, Sophorn Chip, Joungnam Kim, Qi Zhao, Kamalika Moulick, Julia Aguirre, Nian Fen Wu, Paul Greengard et al. · 2007 · Proceedings of the National Academy of Sciences
  6. Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases
    Nicholas M. Kanaan, Gerardo A. Morfini, Nichole E. LaPointe, Gustavo F. Pigino, Kristina R. Patterson, Yuyu Song, Athena Andreadis, Yifan Fu, Scott T. Brady, Lester I. Binder · 2011 · Journal of Neuroscience
  7. Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain
    Katherine J. Kopeikina, George A. Carlson, Rose Pitstick, Adam E. Ludvigson, Alan Peters, Jennifer Irene Luebke, Robert M. Koffie, Matthew P. Frosch, Bradley T. Hyman, Tara L. Spires‐Jones · 2011 · American Journal Of Pathology
  8. Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
    Frandemiche, Marie Lise, De Seranno, Sandrine, Rush, Travis, Borel, Eve, Elie, Auréliane, Arnal, Isabelle, Lanté, Fabien, Buisson, Alain · 2014 · The Journal of Neuroscience
  9. Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation*
    Mondragón-Rodríguez, Siddhartha, Trillaud-Doppia, Emilie, Dudilot, Anthony, Bourgeois, Catherine, Lauzon, Michel, Leclerc, Nicole, Boehm, Jannic · 2012 · Journal of Biological Chemistry
  10. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner
    Juan Carlos Polanco, Benjamin James Scicluna, Andrew Francis Hill, Jürgen Götz · 2016 · Journal of Biological Chemistry
  11. Tau and α‐synuclein in susceptibility to, and dementia in, Parkinson's disease
    An Goris, Caroline H. Williams‐Gray, Graeme R. Clark, Thomas Foltynie, Simon J.G. Lewis, Joanne Brown, Maria Ban, Maria Grazia Spillantini, Alastair Compston, David John Burn et al. · 2007 · Annals of Neurology
  12. Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation
    Jose Francisco Abisambra, Umesh K. Jinwal, Laura J. Blair, John C. O’Leary, Qingyou Li, Sarah Brady, Li Wang, Chantal Guidi, Bo Zhang, Bryce A. Nordhues et al. · 2013 · Journal of Neuroscience
  13. Graded Control of Microtubule Severing by Tubulin Glutamylation
    Max L. Valenstein, Antonina Roll‐Mecak · 2016 · Cell
  14. Loss of Bin1 Promotes the Propagation of Tau Pathology
    Calafate, Sara, Flavin, William, Verstreken, Patrik, Moechars, Diederik · 2016 · Cell Reports
  15. Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice
    Ittner, Arne, Chua, Sook Wern, Bertz, Josefine, Volkerling, Alexander, van der Hoven, Julia, Gladbach, Amadeus, Przybyla, Magdalena, Bi, Mian, van Hummel, Annika, Stevens, Claire H. et al. · 2016 · Science
  16. The Generation of a 17 kDa Neurotoxic Fragment: An Alternative Mechanism by which Tau Mediates β-Amyloid-Induced Neurodegeneration
    Park, So-Young, Ferreira, Adriana · 2005 · The Journal of Neuroscience
  17. Interface between tauopathies and synucleinopathies: A tale of two proteins
    Wendy R. Galpern, Anthony Edward Lang · 2006 · Annals of Neurology
  18. Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains
    Susana Boluda, Michiyo Iba, Bin Zhang, Kevin M. Raible, Virginia M.‐Y. Lee, John Q. Trojanowski · 2014 · Acta Neuropathologica
  19. Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation
    Sara Calafate, Arjan Buist, Katarzyna Miśkiewicz, V. A. Vijayan, Guy Daneels, Bart De Strooper, Joris de Wit, Patrik Verstreken, Diederik Moechars · 2015 · Cell Reports
  20. Single-molecule investigation of the interference between kinesin, tau and MAP2c
    Seitz, Arne, Kojima, Hiroaki, Oiwa, Kazuhiro, Mandelkow, Eva-Maria, Song, Young-Hwa, Mandelkow, Eckhard · 2002 · The EMBO Journal
  21. Central Role of Glycogen Synthase Kinase-3β in Endoplasmic Reticulum Stress-induced Caspase-3 Activation
    Ling Song, Patrizia De Sarno, Richard Scott Jope · 2002 · Journal of Biological Chemistry
  22. Tau truncation during neurofibrillary tangle evolution in Alzheimer’s disease
    Guillozet-Bongaarts, Angela L., Garcia-Sierra, Francisco, Reynolds, Matthew R., Horowitz, Peleg M., Fu, Yifan, Wang, Tianyi, Cahill, Michael E., Bigio, Eileen H., Berry, Robert W., Binder, Lester I. · 2005 · Neurobiology of Aging
  23. MINOR GROOVE-BINDING ARCHITECTURAL PROTEINS: Structure, Function, and DNA Recognition
    Carole A. Bewley, Angela M. Gronenborn, G. Marius Clore · 1998 · Annual Review of Biophysics and Biomolecular Structure
  24. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo
    Norbert Žilka, Peter Filipčík, Peter Koson, Ľubica Fialová, Rostislav Škrabana, Monika Žilková, Gabriela Rolkova, Eva Kontseková, Michal Novák · 2006 · FEBS Letters
  25. A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions
    Violet, Marie, Delattre, Lucie, Tardivel, Meryem, Sultan, Audrey, Chauderlier, Alban, Caillierez, Raphaelle, Talahari, Smail, Nesslany, Fabrice, Lefebvre, Bruno, Bonnefoy, Eliette et al. · 2014 · Frontiers in Cellular Neuroscience
  26. Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau
    Klein, Corinna, Krämer, Eva-Maria, Cardine, Anne-Marie, Schraven, Burkhardt, Brandt, Roland, Trotter, Jacqueline · 2002 · The Journal of Neuroscience
  27. Altered Machinery of Protein Synthesis in Alzheimer's: From the Nucleolus to the Ribosome
    Hernández‐Ortega, Karina, Garcia‐Esparcia, Paula, Gil, Laura, Lucas, José J., Ferrer, Isidre · 2016 · Brain Pathology
  28. How IRE1 Reacts to ER Stress
    David Ron, Stevan R. Hubbard · 2008 · Cell
  29. Tau oligomers and tau toxicity in neurodegenerative disease
    Sarah Ward, Diana S. Himmelstein, Jody K. Lancia, Lester I. Binder · 2012 · Biochemical Society Transactions
  30. Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain
    Troy T. Rohn, Robert A. Rissman, Michael C. Davis, Young‐Eun Kim, Carl W. Cotman, Elizabeth Head · 2002 · Neurobiology of Disease
  31. Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo
    Unterberger, Ursula, Höftberger, Romana, Gelpi, Ellen, Flicker, Helga, Budka, Herbert, Voigtländer, Till · 2006 · Journal of Neuropathology and Experimental Neurology
  32. Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias
    Melissa Erin Murray, Naomi Kouri, Wen-Lang Lin, Clifford R. Jack, Dennis W. Dickson, Prashanthi Vemuri · 2014 · Alzheimer s Research & Therapy
  33. SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination
    Luo, Hong-Bin, Xia, Yi-Yuan, Shu, Xi-Ji, Liu, Zan-Chao, Feng, Ye, Liu, Xing-Hua, Yu, Guang, Yin, Gang, Xiong, Yan-Si, Zeng, Kuan et al. · 2014 · Proceedings of the National Academy of Sciences
  34. Is calpain activity regulated by membranes and autolysis or by calcium and calpastatin?
    Darrel E. Goll, Valery F. Thompson, Richard G. Taylor · 1992 · BioEssays
  35. Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
    Anna J. Kim, Yuanyuan Shi, Richard C. Austin, Geoff H. Werstuck · 2004 · Journal of Cell Science
  36. Tau Cleavage and Dephosphorylation in Cerebellar Granule Neurons Undergoing Apoptosis
    Canu, Nadia, Dus, Laura, Barbato, Christian, Ciotti, Maria T., Brancolini, Claudio, Rinaldi, Anna M., Novak, Michal, Cattaneo, Antonino, Bradbury, Andrew, Calissano, Pietro · 1998 · The Journal of Neuroscience
  37. Huntington's disease is a four-repeat tauopathy with tau nuclear rods
    Fernández-Nogales, Marta, Cabrera, Jorge R, Santos-Galindo, María, Hoozemans, Jeroen J M, Ferrer, Isidro, Rozemuller, Annemieke J M, Hernández, Félix, Avila, Jesús, Lucas, José J · 2014 · Nature Medicine
  38. Phosphorylation Regulates Tau Interactions with Src Homology 3 Domains of Phosphatidylinositol 3-Kinase, Phospholipase Cγ1, Grb2, and Src Family Kinases
    C. Hugh Reynolds, Claire J. Garwood, Selina Wray, Caroline Price, Stuart Kellie, Timothy Pietro Suren Perera, Marketa Zvelebil, Alice Yang, Paul W. Sheppard, Ian M. Varndell et al. · 2008 · Journal of Biological Chemistry
  39. Interaction of Tau with the Neural Membrane Cortex Is Regulated by Phosphorylation at Sites That Are Modified in Paired Helical Filaments
    Maas, Thorsten, Eidenmüller, Jochen, Brandt, Roland · 2000 · Journal of Biological Chemistry
  40. CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity
    Manu Sharma, Jacqueline Burré, Thomas Christian Südhof · 2010 · Nature Cell Biology
  41. Proteomic Identification of Novel Proteins in Cortical Lewy Bodies
    James B. Leverenz, Imran Umar, Qing Wang, Thomas Jude Montine, Pamela J. McMillan, Debby W. Tsuang, Jinghua Jin, Catherine Pan, Jenny Shin, David C. Zhu et al. · 2007 · Brain Pathology
  42. Conformational Diversity of Wild-type Tau Fibrils Specified by Templated Conformation Change
    Frost, Bess, Ollesch, Julian, Wille, Holger, Diamond, Marc I. · 2009 · Journal of Biological Chemistry
  43. Constitutive secretion of tau protein by an unconventional mechanism
    Xiyun Chai, Jeffrey L. Dage, Martin Citron · 2012 · Neurobiology of Disease
  44. Defective ubiquitination of cerebral proteins in Alzheimer's disease
    M. Lopez Salon, Laura Morelli, Eduardo M. Casta�o, Eduardo F. Soto, Juana Maria Pasquini · 2000 · Journal of Neuroscience Research
  45. 14-3-3ζ Is an Effector of Tau Protein Phosphorylation
    Mitsuko Hashiguchi, Kazuya Sobue, Hemant K. Paudel · 2000 · Journal of Biological Chemistry
  46. Disease-related Modifications in Tau Affect the Interaction between Fyn and Tau
    Kiran Bhaskar, Shu-Hui C. Yen, Gloria S. Lee · 2005 · Journal of Biological Chemistry
  47. cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins
    Sudarsanareddy Lokireddy, Nikolay Vadimovich Kukushkin, Alfred Lewis Goldberg · 2015 · Proceedings of the National Academy of Sciences
  48. Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy
    Chen‐Chen Tan, Jin‐Tai Yu, Meng‐Shan Tan, Teng Jiang, Xi‐Chen Zhu, Lan Tan · 2013 · Neurobiology of Aging
  49. Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
    Lars Matthias Ittner, Thomas Fath, Yazi Diana Ke, Mian Bi, Janet van Eersel, Kong M. Li, Peter William Gunning, Jürgen Götz · 2008 · Proceedings of the National Academy of Sciences
  50. Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration
    Xiaoyu Li, Yatender Kumar, Hans Zempel, Eva‐Maria Mandelkow, Jacek Biernat, Eckhard Mandelkow · 2011 · The EMBO Journal
  51. Lithium Reduces Tau Phosphorylation but Not Aβ or Working Memory Deficits in a Transgenic Model with Both Plaques and Tangles
    Antonella Caccamo, Salvatore Oddo, Lana X. Tran, Frank M. LaFerla · 2007 · American Journal Of Pathology
  52. Identification of nuclear tau isoforms in human neuroblastoma cells.
    P A Loomis, Thomas H. Howard, R P Castleberry, Lester I. Binder · 1990 · Proceedings of the National Academy of Sciences
  53. Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein
    Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Lucie Delattre, Sébastien Carrier, Anne Loyens, Marie‐Christine Galas, Luc Bousset, Ronald Melki et al. · 2014 · PLoS ONE
  54. Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation
    Mirbaha, Hilda, Holmes, Brandon B., Sanders, David W., Bieschke, Jan, Diamond, Marc I. · 2015 · Journal of Biological Chemistry
  55. Implications of the serine protease HtrA1 in amyloid precursor protein processing
    Grau, Sandra, Baldi, Alfonso, Bussani, Rossana, Tian, Xiaodan, Stefanescu, Raluca, Przybylski, Michael, Richards, Peter, Jones, Simon A., Shridhar, Viji, Clausen, Tim et al. · 2005 · Proceedings of the National Academy of Sciences
  56. Early N-Terminal Changes and Caspase-6 Cleavage of Tau in Alzheimer's Disease
    Horowitz, Peleg M., Patterson, Kristina R., Guillozet-Bongaarts, Angela L., Reynolds, Matthew R., Carroll, Christopher A., Weintraub, Susan T., Bennett, David A., Cryns, Vincent L., Berry, Robert W., Binder, Lester I. · 2004 · The Journal of Neuroscience
  57. Are tau aggregates toxic or protective in tauopathies?
    Cowan, Catherine M., Mudher, Amrit · 2013 · Frontiers in Neurology
  58. Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
    Peeraer, Eve, Bottelbergs, Astrid, Van Kolen, Kristof, Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Mahieu, Michel, Duytschaever, Hilde, Ver Donck, Luc, Torremans, An, Sluydts, Ellen et al. · 2015 · Neurobiology of Disease
  59. Tau phosphorylation by GSK-3β promotes tangle-like filament morphology
    Carolyn A. Rankin, Qian Sun, T.C. Gamblin · 2007 · Molecular Neurodegeneration
  60. Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice
    Simona Capsoni, Sabina Giannotta, Antonino Cattaneo · 2002 · Proceedings of the National Academy of Sciences
  61. Loss of <i>O</i> -GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration
    Wang, Andrew C., Jensen, Elizabeth H., Rexach, Jessica E., Vinters, Harry V., Hsieh-Wilson, Linda C. · 2016 · Proceedings of the National Academy of Sciences
  62. Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins—a role in nuclear localization
    Tony Lefebvre, Stéphanie Ferreira, L. Dupont-Wallois, Thierry Bussière, Marie-Joëlle Dupire, André Delacourte, Jean‐Claude Michalski, Marie‐Laure Caillet‐Boudin · 2003 · Biochimica et Biophysica Acta (BBA) - General Subjects
  63. The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer’s Disease
    Zhenzhen Liu, Tao Li, Ping Li, Nannan Wei, Zhiquan Zhao, Huimin Liang, Xin‐Ying Ji, Wenwu Chen, Mengzhou Xue, Jianshe Wei · 2015 · Oxidative Medicine and Cellular Longevity
  64. Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation
    Liu, Fei, Li, Bin, Tung, E‐Jan, Grundke‐Iqbal, Inge, Iqbal, Khalid, Gong, Cheng‐Xin · 2007 · European Journal of Neuroscience
  65. Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
    Y. P. Wang, Jacek Biernat, Marcus Pickhardt, Eckhard Mandelkow�, Eckhard Mandelkow� · 2007 · Proceedings of the National Academy of Sciences
  66. DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
    Sarah N. Fontaine, Dali Zheng, Jonathan J. Sabbagh, Mackenzie D. Martin, Dale Chaput, April L. Darling, Justin H. Trotter, Andrew R. Stothert, Bryce A. Nordhues, April L. Lussier et al. · 2016 · The EMBO Journal
  67. Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain.
    Litersky, J M, Johnson, G V · 1992 · Journal of Biological Chemistry
  68. Tau co-organizes dynamic microtubule and actin networks
    Elie, Auréliane, Prezel, Elea, Guérin, Christophe, Denarier, Eric, Ramirez-Rios, Sacnicte, Serre, Laurence, Andrieux, Annie, Fourest-Lieuvin, Anne, Blanchoin, Laurent, Arnal, Isabelle · 2015 · Scientific Reports
  69. Tau phosphorylation affects its axonal transport and degradation
    Teresa Rodríguez-Martín, Inmaculada Cuchillo‐Ibáñez, Wendy J. Noble, Fanon Nyenya, Brian H. Anderton, Diane P. Hanger · 2013 · Neurobiology of Aging
  70. The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies
    Diana A.T. Nijholt, Elise S. van Haastert, Annemieke J.M. Rozemüller, Wiep Scheper, Jeroen J.M. Hoozemans · 2011 · The Journal of Pathology
  71. Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved Mouse
    Emmanuel Planel, Kaori Yasutake, Shinobu C. Fujita, Koichi Ishiguro · 2001 · Journal of Biological Chemistry
  72. The “Jaws” of the Tau-Microtubule Interaction
    Marco D. Mukrasch, Martin von Bergen�, Jacek Biernat, Daniela Fischer, Christian Griesinger, Eckhard Mandelkow�, Markus Zweckstetter · 2007 · Journal of Biological Chemistry
  73. The Neuronal Microtubule‐Associated Protein Tau Is a Substrate for Caspase‐3 and an Effector of Apoptosis
    Luisa Fasulo, Gabriele Ugolini, Michela Visintin, Andrew M. Bradbury, Claudio Brancolini, Vittorio Verzillo, Michal Novák, Antonino Cattaneo · 2000 · Journal of Neurochemistry
  74. Tau oligomers and aggregation in Alzheimer’s disease
    Marco Antonio Meraz‐Ríos, Karla Isabel Lira-de León, Victoria Campos‐Peña, Martha A. De Anda-Hernández, Raúl Mena‐López · 2009 · Journal of Neurochemistry
  75. Degradation of Tau by Lysosomal Enzyme Cathepsin D: Implication for Alzheimer Neurofibrillary Degeneration
    Á. Kenessey, P. Nacharaju, L. Ko, S. Yen · 1997 · Journal of Neurochemistry
  76. Thrombin and Prothrombin Are Expressed by Neurons and Glial Cells and Accumulate in Neurofibrillary Tangles in Alzheimer Disease Brain
    Tetsuaki Arai, Judith Miklossy A, Andis Klegeris, Jian‐Ping Guo, Patrick L. McGeer · 2006 · Journal of Neuropathology & Experimental Neurology
  77. Thrombina
    John W. Fenton · 1986 · Annals of the New York Academy of Sciences
  78. Caspase-2 cleavage of tau reversibly impairs memory
    Zhao, Xiaohui, Kotilinek, Linda A, Smith, Benjamin, Hlynialuk, Chris, Zahs, Kathleen, Ramsden, Martin, Cleary, James, Ashe, Karen H · 2016 · Nature Medicine
  79. The active form of glycogen synthase kinase-3? is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
    Allal Boutajangout, Karelle Leroy, M. Authelet, Brian H. Anderton, Jean‐Pierre Brion, James Robert Woodgett · 2002 · Acta Neuropathologica
  80. Identification of amino‐terminally cleaved tau fragments that distinguish progressive supranuclear palsy from corticobasal degeneration
    Tetsuaki Arai, Kenji Ikeda, Haruhiko Akiyama, Takashi Nonaka, Masato Hasegawa, Koichi Ishiguro, Shuji Iritani, Kuniaki Tsuchiya, Eizo Iseki, Saburo Yagishita et al. · 2003 · Annals of Neurology
  81. Interaction of tau protein with the dynactin complex
    Enrico Magnani, Juan Fan, Laura Gasparini, Matthew Golding, Meredith Williams, Giampietro Schiavo, Michel Goedert, Linda Amos, Maria Grazia Spillantini · 2007 · The EMBO Journal
  82. Tyrosine 394 Is Phosphorylated in Alzheimer's Paired Helical Filament Tau and in Fetal Tau with c-Abl as the Candidate Tyrosine Kinase
    Pascal Derkinderen, Timothy M.E. Scales, Diane P. Hanger, Kit‐Yi Leung, Helen L. Byers, Malcolm Andrew Ward, Christof Lenz, Caroline Price, Ian N. Bird, Timothy Pietro Suren Perera et al. · 2005 · Journal of Neuroscience
  83. Tau – an inhibitor of deacetylase HDAC6 function
    Perez, Mar, Santa‐Maria, Ismael, De Barreda, Elena Gomez, Zhu, Xiongwei, Cuadros, Raquel, Cabrero, Jose Roman, Sanchez‐Madrid, Francisco, Dawson, Hana N., Vitek, Michael P., Perry, George et al. · 2009 · Journal of Neurochemistry
  84. Substantia nigra tangles are related to gait impairment in older persons
    Julie A. Schneider, Jialiang Li, Yan Li, Robert S. Wilson, Jeffrey H. Kordower, David Alan Bennett · 2005 · Annals of Neurology
  85. Tau isoform regulation is region‐ and cell‐specific in mouse brain
    McMillan, Pamela, Korvatska, Elena, Poorkaj, Parvoneh, Evstafjeva, Zana, Robinson, Linda, Greenup, Lynne, Leverenz, James, Schellenberg, Gerard D., D'Souza, Ian · 2008 · Journal of Comparative Neurology
  86. Tau protein and tau aggregation inhibitors
    Bruno Bulic, Marcus Pickhardt, Eva‐Maria Mandelkow, Eckhard Mandelkow� · 2010 · Neuropharmacology
  87. Reduction of acetylated alpha-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease.
    Bart Hempen, J. Brion · 1996 · Journal of Neuropathology and Experimental Neurology
  88. Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin
    Anne M. Cataldo, C.Y. Thayer, Edward D. Bird, Timothy R. Wheelock, Ralph A. Nixon · 1990 · Brain Research
  89. Structural Impact of Heparin Binding to Full-Length Tau As Studied by NMR Spectroscopy
    Nathalie Sibille, Alain Sillen, Arnaud Leroy, Jean‐Michel Wieruszeski, Barbara Mulloy, Isabelle Landrieu, Guy M. Lippens · 2006 · Biochemistry
  90. Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration
    Sanchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastian, Sanchez-Mico, Maria, Sanchez-Varo, Raquel, Nuñez-Diaz, Cristina, Trujillo-Estrada, Laura, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia et al. · 2016 · Acta Neuropathologica
  91. The role of tau kinases in Alzheimer's disease.
    Philip J. Dolan, Gail V.W. Johnson · 2010 · PubMed
  92. Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons
    Quintanilla, Rodrigo A., Matthews-Roberson, Tori A., Dolan, Philip J., Johnson, Gail V.W. · 2009 · Journal of Biological Chemistry
  93. Thrombin accumulation in brains of patients with Alzheimer's disease
    Haruhiko Akiyama, Kenji Ikeda, Hiromi Kondo, Patrick L. McGeer · 1992 · Neuroscience Letters
  94. Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
    Matthew E. Seward, Eric Swanson, Andrés Norambuena, Anja Reimann, J. Nicholas Cochran, Rong Li, Erik D. Roberson, George S. Bloom · 2013 · Journal of Cell Science
  95. Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo
    Angela L. Guillozet-Bongaarts, Michael E. Cahill, Vincent L. Cryns, Matthew R. Reynolds, Robert W. Berry, Lester I. Binder · 2006 · Journal of Neurochemistry
  96. Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
    Inoue, Keiichi, Rispoli, Joanne, Kaphzan, Hanoch, Klann, Eric, Chen, Emily I, Kim, Jongpil, Komatsu, Masaaki, Abeliovich, Asa · 2012 · Molecular Neurodegeneration
  97. Untitled work
    1995 · PubMed
  98. Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization
    Sjöberg, Marcela K., Shestakova, Elena, Mansuroglu, Zeyni, Maccioni, Ricardo B., Bonnefoy, Eliette · 2006 · Journal of Cell Science
  99. Degradation of tau protein by autophagy and proteasomal pathways
    Wang, Yipeng, Mandelkow, Eckhard · 2012 · Biochemical Society Transactions
  100. Axonal Tau mRNA Localization Coincides with Tau Protein in Living Neuronal Cells and Depends on Axonal Targeting Signal
    Stella Aronov, Gonzalo Aranda, Leah Behar, Irith Ginzburg · 2001 · Journal of Neuroscience
  101. Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins
    Xia‐Chun Li, Yu Hu, Zhi-Hao Wang, Yu Luo, Yao Zhang, Xiuping Liu, Qiong Feng, Qun Wang, Keqiang Ye, Gong‐Ping Liu et al. · 2016 · Scientific Reports
  102. Proteolysis of tau by calpain
    Johnson, Gail V.W., Jope, Richard S., Binder, Lester I. · 1989 · Biochemical and Biophysical Research Communications
  103. Nuclear Tau and Its Potential Role in Alzheimer’s Disease
    Bukar Maina, Mahmoud, Al-Hilaly, Youssra, Serpell, Louise · 2016 · Biomolecules
  104. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment
    Sohn, Peter Dongmin, Tracy, Tara E., Son, Hye-In, Zhou, Yungui, Leite, Renata E. P., Miller, Bruce L., Seeley, William W., Grinberg, Lea T., Gan, Li · 2016 · Molecular Neurodegeneration
  105. A distinct familial presenile dementia with a novel missense mutation in the tau gene
    Masaaki Iijima, Takeshi Tabira, Parvoneh Poorkaj, Gerard D. Schellenberg, John Q. Trojanowski, Virginia M.‐Y. Lee, Marie Luise Schmidt, Keikichi Takahashi, Toru Nabika, Takahisa Matsumoto et al. · 1999 · Neuroreport
  106. Molecular motors implicated in the axonal transport of tau and α-synuclein
    Michelle A. Utton, Wendy J. Noble, Josephine E. Hill, Brian H. Anderton, Diane P. Hanger · 2005 · Journal of Cell Science
  107. Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons
    Sven Konzack, Edda Thies, Alexander Marx, Eva‐Maria Mandelkow, Eckhard Mandelkow� · 2007 · Journal of Neuroscience
  108. Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
    Lars Matthias Ittner, Yazi Diana Ke, Jürgen Götz · 2009 · Journal of Biological Chemistry
  109. Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus
    Chang Liu, Jürgen Götz · 2013 · PLoS ONE
  110. Phosphorylation of Tau Protein as the Link between Oxidative Stress, Mitochondrial Dysfunction, and Connectivity Failure: Implications for Alzheimer’s Disease
    Siddhartha Mondragón‐Rodríguez, George L. Perry, Xiongwei Zhu, Paula Isabel Moreira, Mariana Acevedo, Sylvain Williams · 2013 · Oxidative Medicine and Cellular Longevity
  111. Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice
    Bi, Mian, Ittner, Arne, Ke, Yazi D., Götz, Jürgen, Ittner, Lars M. · 2011 · PLoS ONE
  112. Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau
    Samuel J. Jackson, Caroline Kerridge, Jane Cooper, Annalisa Cavallini, Benjamin Falcon, Claire V. Cella, Alessia Landi, Philip G. Szekeres, Tracey K. Murray, Zeshan Ahmed et al. · 2016 · Journal of Neuroscience
  113. Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy
    Nahuai Badiola, Rita Machado de Oliveira, Federico Herrera, Cristina Guardia‐Laguarta, Susana A. Gonçalves, Marta Pera, Marc Suárez‐Calvet, Jordi Clarimón, Tiago F. Outeiro, Alberto Lleó · 2011 · PLoS ONE
  114. Accumulation of Aspartic Acid 421 - and Glutamic Acid 391 -Cleaved Tau in Neurofibrillary Tangles Correlates With Progression in Alzheimer Disease
    Gustavo Basurto‐Islas, José Luna‐Muñoz, Angela L. Guillozet-Bongaarts, Lester I. Binder, Raúl Mena, Francisco García‐Sierra · 2008 · Journal of Neuropathology & Experimental Neurology
  115. TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau
    Maxime W.C. Rousseaux, María de Haro, Cristian A. Lasagna‐Reeves, Antonia De Maio, Jeehye Park, Paymaan Jafar‐Nejad, Ismael Al‐Ramahi, Ajay Sharma, Lauren See, Nan Lü et al. · 2016 · eLife
  116. The microtubule-associated tau protein has intrinsic acetyltransferase activity
    Cohen, Todd J, Friedmann, Dave, Hwang, Andrew W, Marmorstein, Ronen, Lee, Virginia M Y · 2013 · Nature Structural &amp; Molecular Biology
  117. Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases
    Claudia Schwab, Anthony J. DeMaggio, Nupur Ghoshal, Lester I. Binder, Jeff Kuret, Patrick L. McGeer · 2000 · Neurobiology of Aging
  118. Dynamic association of tau with neuronal membranes is regulated by phosphorylation
    Pooler, Amy M., Usardi, Alessia, Evans, Catherine J., Philpott, Karen L., Noble, Wendy, Hanger, Diane P. · 2012 · Neurobiology of Aging
  119. Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo
    Vikram Khurana, Ilan Elson‐Schwab, Tudor A. Fulga, Katherine A. Sharp, Carin A. Loewen, Erin E. Mulkearns-Hubert, Jaana Tyynelä, Clemens R. Scherzer, Mel Β. Feany · 2010 · PLoS Genetics
  120. Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways
    Norbert Žilka, Zuzana Kazmerova, Santosh Jadhav, Peter Neradil, Aladár Maďari, Dominika Obetkova, Ondrej Bugos, Michal Novák · 2012 · Journal of Neuroinflammation
  121. A Genomic Screen for Modifiers of Tauopathy Identifies Puromycin-Sensitive Aminopeptidase as an Inhibitor of Tau-Induced Neurodegeneration
    Karsten, Stanislav L., Sang, Tzu-Kang, Gehman, Lauren T., Chatterjee, Shreyasi, Liu, Jiankai, Lawless, George M., Sengupta, Soma, Berry, Robert W., Pomakian, Justine, Oh, Hyun S. et al. · 2006 · Neuron
  122. Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment
    Robert John Hatch, Wei Yan, Di Xia, Jürgen Götz · 2017 · Acta Neuropathologica
  123. Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin
    Mansuroglu, Zeyni, Benhelli-Mokrani, Houda, Marcato, Vasco, Sultan, Audrey, Violet, Marie, Chauderlier, Alban, Delattre, Lucie, Loyens, Anne, Talahari, Smail, Bégard, Séverine et al. · 2016 · Scientific Reports
  124. Interaction of Tau Protein with Model Lipid Membranes Induces Tau Structural Compaction and Membrane Disruption
    Emmalee M. Jones, Manish Kant Dubey, Phillip J Camp, Briana C. Vernon, Jacek Biernat, Eckhard Mandelkow�, Jaroslaw P. Majewski, Eva Y. Chi · 2012 · Biochemistry
  125. Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
    Chang Liu, Xiaomin Song, Rebecca M. Nisbet, Jürgen Götz · 2016 · Journal of Biological Chemistry
  126. O-GlcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers
    Scott A. Yuzwa, Adrienne H. Cheung, Mark Okon, Lawrence P. McIntosh, David J. Vocadlo · 2014 · Journal of Molecular Biology
  127. Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis
    Ramesh J. L. Kandimalla, P. Hemachandra Reddy · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  128. The tubulin-binding sequence of brain microtubule-associated proteins, tau and MAP-2, is also involved in actin binding
    Correas, I, Padilla, R, Avila, J · 1990 · Biochemical Journal
  129. CSPα knockout causes neurodegeneration by impairing SNAP‐25 function
    Manu Sharma, Jacqueline Burré, Peter Bronk, Yingsha Zhang, Wei Xu, Thomas Christian Südhof · 2011 · The EMBO Journal
  130. Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer’s disease, and in Parkinson’s disease and related α-synucleinopathies
    Gerard Muntané, Esther Dalfó, Ana Martı́nez, Isidró Ferrer · 2008 · Neuroscience
  131. Tau‐tubulin kinase 1 (TTBK1), a neuron‐specific tau kinase candidate, is involved in tau phosphorylation and aggregation
    Shinji Sato, Ronald L. Cerny, James L. Buescher, Tsuneya Ikezu · 2006 · Journal of Neurochemistry
  132. The proline-rich domain of tau plays a role in interactions with actin
    He, Hai Jin, Wang, Xing Sheng, Pan, Rong, Wang, Dong Liang, Liu, Ming Nan, He, Rong Qiao · 2009 · BMC Cell Biology
  133. Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
    Funk, Kristen E., Thomas, Stefani N., Schafer, Kelsey N., Cooper, Grace L., Liao, Zhongping, Clark, David J., Yang, Austin J., Kuret, Jeff · 2014 · Biochemical Journal
  134. ER stress is involved in Aβ‐induced GSK‐3β activation and tau phosphorylation
    Rosa Resende, Elisabete B. Ferreiro, Cláudia Pereira, Catarina Resende Oliveira · 2008 · Journal of Neuroscience Research
  135. Inhibition of Tau Polymerization by Its Carboxy-Terminal Caspase Cleavage Fragment
    Berry, R. W., Abraha, A., Lagalwar, S., LaPointe, N., Gamblin, T. C., Cryns, V. L., Binder, L. I. · 2003 · Biochemistry
  136. Tau protein diffuses along the microtubule lattice
    Hinrichs, Maike H., Jalal, Avesta, Brenner, Bernhard, Mandelkow, Eckhard, Kumar, Satish, Scholz, Tim · 2012 · Journal of Biological Chemistry
  137. Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes
    Ismael Santa‐María, Merina Varghese, Hanna Ksiȩżak-Reding, Anastasiya Dzhun, Jun Wang, Giulio Maria Pasinetti · 2012 · Journal of Biological Chemistry
  138. Tau Structures
    Avila, Jesus, Jiménez, Juan S., Sayas, Carmen L., Bolós, Marta, Zabala, Juan C., Rivas, Germán, Hernández, Felix · 2016 · Frontiers in Aging Neuroscience
  139. The role of tau in the pathological process and clinical expression of Huntington’s disease
    Romina Vuono, Sophie Winder‐Rhodes, Rohan de Silva, Giulia Cisbani, Janelle Drouin‐Ouellet, REGISTRY Investigators of the European Huntington’s Disease Network, Maria Grazia Spillantini, Francesca Cicchetti, Roger A. Barker · 2015 · Brain
  140. Proteolytic processing of tau
    Yipeng Wang, Sarika Garg, Eva‐Maria Mandelkow, Eckhard Mandelkow� · 2010 · Biochemical Society Transactions
  141. Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis
    Janice Yuen Shan Ho, Xifei Yang, Jeffery Chi-Fai Lau, Clara Hiu-Ling Hung, Suthicha Wuwongse, Qishan Zhang, Jian‐Zhi Wang, Larry Baum, Kwok‐Fai So, Raymond Chuen‐Chung Chang · 2012 · Journal of Alzheimer s Disease
  142. Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway
    Tsuyoshi Morita, Kenji Sobue · 2009 · Journal of Biological Chemistry
  143. Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease
    R. Mena, Patricia C. Edwards, Charles R. Harrington, Elizabeta B. Mukaetova‐Ladinska, Claude M. Wischik · 1996 · Acta Neuropathologica
  144. Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion
    Ahmed, Tariq, Van der Jeugd, Ann, Blum, David, Galas, Marie-Christine, D’Hooge, Rudi, Buee, Luc, Balschun, Detlef · 2014 · Neurobiology of Aging
  145. The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner
    Anne Gauthier‐Kemper, Carina Weissmann, Nataliya Golovyashkina, Zsofia Sebö-Lemke, Gerard Drewes, Volker Gerke, Jürgen J. Heinisch, Roland Brandt · 2011 · The Journal of Cell Biology
  146. Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
    Kanaan, Nicholas M., Morfini, Gerardo, Pigino, Gustavo, LaPointe, Nichole E., Andreadis, Athena, Song, Yuyu, Leitman, Ellen, Binder, Lester I., Brady, Scott T. · 2012 · Neurobiology of Aging
  147. Role of the Tau N-terminal region in microtubule stabilization revealed by newendogenous truncated forms
    Maxime J. Derisbourg, Coline Leghay, Giovanni Chiappetta, Francisco-José Fernández-Gómez, Cyril Laurent, Dominique Demeyer, Sébastien Carrier, Valérie Buée‐Scherrer, David L Blum, Joëlle Vinh et al. · 2015 · Scientific Reports
  148. Amyloid-β Toxicity and Tau Hyperphosphorylation are Linked Via RCAN1 in Alzheimer's Disease
    Ana Lloret, Mari-Carmen Badía, Esther Giraldo, Gennady Ermak, Maria-Dolores Alonso, Federico Vicente Pallardó, Kelvin J.A. Davies, José Viña · 2011 · Journal of Alzheimer s Disease
  149. Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation
    Caroline Smet‐Nocca, Malgorzata Broncel, Jean‐Michel Wieruszeski, Caroline Tokarski, Xavier Hanoulle, Arnaud Leroy, Isabelle Landrieu, Christian H. Rolando, Guy M. Lippens, Christian P. R. Hackenberger · 2011 · Molecular BioSystems
  150. Pre‐synaptic C‐terminal truncated tau is released from cortical synapses in Alzheimer's disease
    Sokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Gonzalez, Bianca, Vinters, Harry V., Miller, Carol A., Cornwell, Lindsey, Poon, Wayne W., Gylys, Karen H. · 2015 · Journal of Neurochemistry
  151. Microtubules in health and degenerative disease of the nervous system
    Andrew J. Matamoros, Peter W. Baas · 2016 · Brain Research Bulletin
  152. Dephosphorylation of Tau by Protein Phosphatase 5
    Fei Liu, Khalid Iqbal, Inge Grundke, Sandra S. Rossie, Cheng‐Xin Gong · 2004 · Journal of Biological Chemistry
  153. A novel tau transcript in cultured human neuroblastoma cells expressing nuclear tau.
    Yu Wang, P A Loomis, Raymond P. Zinkowski, Lester I. Binder · 1993 · The Journal of Cell Biology
  154. Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer‐induced <scp>AMPA</scp> glutamate receptor signaling deficits
    Miller, Eric C., Teravskis, Peter J., Dummer, Benjamin W., Zhao, Xiaohui, Huganir, Richard L., Liao, Dezhi · 2014 · European Journal of Neuroscience
  155. Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein
    Jochen Eidenmüller, Thomas Fath, Thorsten Maas, Madeline Pool, Estelle Sontag, Roland Brandt · 2001 · Biochemical Journal
  156. NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease
    Corsetti, V., Florenzano, F., Atlante, A., Bobba, A., Ciotti, M.T., Natale, F., Della Valle, F., Borreca, A., Manca, A., Meli, G. et al. · 2015 · Human Molecular Genetics
  157. Tau‐targeted treatment strategies in Alzheimer's disease
    Jürgen Götz, Arne Ittner, Lars Matthias Ittner · 2011 · British Journal of Pharmacology
  158. Expression of microtubule-associated proteins MAP2 and tau in cultured rat brain oligodendrocytes
    Müller, Reinhold, Heinrich, Michael, Heck, Susanne, Blohm, Dietmar, Richter-Landsberg, Christiane · 1997 · Cell and Tissue Research
  159. Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro
    Hanna Ksiȩżak-Reding, Han Kyoung Pyo, Boris Feinstein, Giulio Maria Pasinetti · 2003 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  160. Determination of Peptide Substrate Specificity for μ-Calpain by a Peptide Library-based Approach
    Dominic Cuerrier, Tudor Moldoveanu, Peter L. Davies · 2005 · Journal of Biological Chemistry
  161. Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies
    Irwin, David J., Cohen, Todd J., Grossman, Murray, Arnold, Steven E., McCarty-Wood, Elisabeth, Van Deerlin, Vivianna M., Lee, Virginia M.-Y., Trojanowski, John Q. · 2013 · The American Journal of Pathology
  162. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement
    Lee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded et al. · 2016 · Cell Reports
  163. Pathways of tau fibrillization
    Jeff Kuret, Carmen N. Chirita, Erin E. Congdon, Theresa Joseph Kannanayakal, Guibin Li, Mihaela Necula, Haishan Yin, Qi Zhong · 2004 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  164. Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease
    W. Noble, C. Garwood, J. Stephenson, Anna M. Kinsey, D. Hanger, B. Anderton · 2009 · The FASEB Journal
  165. Soluble Aβ Promotes Wild-Type Tau Pathology<i>In Vivo</i>
    Chabrier, Meredith A., Blurton-Jones, Mathew, Agazaryan, Andranik A., Nerhus, Joy L., Martinez-Coria, Hilda, LaFerla, Frank M. · 2012 · The Journal of Neuroscience
  166. Competition for Microtubule-binding with Dual Expression of Tau Missense and Splice Isoforms
    Mei Lü, Kenneth S. Kosik · 2001 · Molecular Biology of the Cell
  167. Tau isoform composition influences rate and extent of filament formation
    Zhong, Qi, Congdon, Erin E., Nagaraja, Haikady N., Kuret, Jeff · 2012 · Journal of Biological Chemistry
  168. A novel DYRK1A (Dual specificity tyrosine phosphorylation‐regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro
    Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, C. de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard et al. · 2014 · Journal of Neurochemistry
  169. NMR Investigation of the Interaction between the Neuronal Protein Tau and the Microtubules
    Alain Sillen, Pascale Barbier, Isabelle Landrieu, Sylvie Lefebvre, Jean‐Michel Wieruszeski, Arnaud Leroy, Vincent Peyrot, Guy M. Lippens · 2007 · Biochemistry
  170. Tau Binds to Lipid Membrane Surfaces via Short Amphipathic Helices Located in Its Microtubule-Binding Repeats
    Elka R. Georgieva, Shifeng Xiao, Peter P. Borbat, Jack H. Freed, David Eliezer · 2014 · Biophysical Journal
  171. The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome
    C. Geeth Gunawardana, Mohadeseh Mehrabian, Xinzhu Wang, Iris Mueller, Isabela Lubambo, James E. N. Jonkman, Hansen Wang, Gerold Schmitt‐Ulms · 2015 · Molecular & Cellular Proteomics
  172. Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo
    Peng Wang, Gérard Joberty, Arjan Buist, Alexandre Vanoosthuyse, Ilie‐Cosmin Stancu, Bruno Vasconcelos, Nathalie Pierrot, Maria Faelth-Savitski, Pascal Kienlen‐Campard, Jean‐Noël Octave et al. · 2017 · Acta Neuropathologica
  173. Age-Dependent Effects of A53T Alpha-Synuclein on Behavior and Dopaminergic Function
    Adam W. Oaks, Maya Frankfurt, David Isaac Finkelstein, Anita Sidhu · 2013 · PLoS ONE
  174. Glycogen Synthase Kinase 3β Induces Caspase-cleaved Tau Aggregation in Situ
    Jae‐Hyeon Cho, Gail V.W. Johnson · 2004 · Journal of Biological Chemistry
  175. Tau antisera recognize neurofibrillary tangles in a range of neurodegenerative disorders
    Catharine L. Joachim, James H. Morris, K S Kosik, Dennis J. Selkoe · 1987 · Annals of Neurology
  176. The dendritic hypothesis for Alzheimer's disease pathophysiology
    Cochran, J. Nicholas, Hall, Alicia M., Roberson, Erik D. · 2014 · Brain Research Bulletin
  177. A new function of microtubule-associated protein tau: Involvement in chromosome stability
    Giacomina Rossi, Leda Dalprà, Francesca Crosti, Sara Lissoni, Francesca L. Sciacca, Marcella Catania, Michela Mangieri, Giorgio Giaccone, Danilo Croci, Fabrizio Tagliavini · 2008 · Cell Cycle
  178. Presence of tau in isolated nuclei from human brain
    Roseann M. Rady, Raymond P. Zinkowski, Lester I. Binder · 1995 · Neurobiology of Aging
  179. CSF tau and tau/Aβ42 predict cognitive decline in Parkinson's disease
    Changqin Liu, Brenna Cholerton, Min Yan Shi, Carmen Ginghină, Kevin C. Cain, Peggy Auinger, Jing Zhang · 2015 · Parkinsonism & Related Disorders
  180. Calpain-Mediated Tau Cleavage: A Mechanism Leading to Neurodegeneration Shared by Multiple Tauopathies
    Ferreira, Adriana, Bigio, Eileen H · 2011 · Molecular Medicine
  181. Tau and src family tyrosine kinases
    Gloria S. Lee · 2004 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  182. Are Tangles as Toxic as They Look?
    Tara L. Spires‐Jones, Katherine J. Kopeikina, Robert M. Koffie, Alix de Calignon, Bradley T. Hyman · 2011 · Journal of Molecular Neuroscience
  183. Glial Tau Pathology in Neurodegenerative Diseases: Their Nature and Comparison with Neuronal Tangles
    Kenji Ikeda, Haruhiko Akiyama, Tetsuaki Arai, T. Nishimura · 1998 · Neurobiology of Aging
  184. Cytosolic Proteolysis of τ by Cathepsin D in Hippocampus Following Suppression of Cathepsins B and L
    Eric Bednarski, GARY S. LYNCH · 1996 · Journal of Neurochemistry
  185. Somatodendritic localization of phosphorylated tau in neonatal and adult rat cerebral cortex
    Ken Tashiro, Masato Hasegawa, Yasuo Ihara, Takeshi Iwatsubo · 1997 · Neuroreport
  186. τ Protein from Alzheimer's Disease Patients Is Glycated at Its Tubulin‐Binding Domain
    Ledesma, M. Dolores, Bonay, Pedro, Avila, Jesús · 1995 · Journal of Neurochemistry
  187. Determinants of amyloid fibril degradation by the PDZ protease HTRA1
    Simon Poepsel, Andreas Sprengel, Barbara Saccà, Farnusch Kaschani, Markus Kaiser, Christos Gatsogiannis, Stefan Raunser, Tim Clausen, Michael Ehrmann · 2015 · Nature Chemical Biology
  188. An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies
    Rohan de Silva, Tammaryn Lashley, Catherine Strand, Anna-Maria Shiarli, Jing Shi, Jinzhou Tian, Kathryn L. Bailey, Peter Davies, Eileen H. Bigio, Kunimasa Arima et al. · 2006 · Acta Neuropathologica
  189. Interneuronal Transfer of Human Tau Between Lamprey Central Neurons in situ
    WonHee Kim, Sangmook Lee, Cheolwha Jung, Ambar Ahmed, Gloria S. Lee, Garth F. Hall · 2010 · Journal of Alzheimer s Disease
  190. Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression
    Mala V. Rao, Panaiyur S. Mohan, Corrinne M. Peterhoff, Dun‐Sheng Yang, Stephen Schmidt, Philip H. Stavrides, Jabbar Campbell, Yuanxin Chen, Ying Jiang, Peter A. Paskevich et al. · 2008 · Journal of Neuroscience
  191. Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation
    Lea T. Grinberg, Xuehua Wang, Chao Wang, Peter Sohn, Panos Theofilas, Manu Sidhu, John Benjamin Arevalo, Helmut Heinsen, Eric Jinsheng Huang, Howard J. Rosen et al. · 2013 · Acta Neuropathologica
  192. Structural Insight into Tau Protein’s Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation
    Yin Luo, Buyong Ma, Ruth Nussinov, Guanghong Wei · 2014 · The Journal of Physical Chemistry Letters
  193. α-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton
    Alessandro Esposito, Christoph Peter Dohm, Pawel Kermer, Mathias Bähr, Fred Silvester Wouters · 2007 · Neurobiology of Disease
  194. Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5
    F Liu, Tanweer Zaidi, Khalid Iqbal, Inge Grundke, Cheng‐Xin Gong · 2002 · Neuroscience
  195. Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma
    Marius Chiasseu, Jorge L. Cueva Vargas, Laurie Destroismaisons, Christine Vande Velde, Nicole M. Leclerc, Adriana Di Polo · 2016 · Journal of Neuroscience
  196. Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.
    Leroy, Karelle, Ando, Kunie, Héraud, Céline, Yilmaz, Zehra, Authelet, Michèle, Boeynaems, Jean-Marie, Buée, Luc, De Decker, Robert, Brion, Jean-Pierre · 2010 · Journal of Alzheimer's Disease
  197. Tau phosphorylation increases in symptomatic mice overexpressing A30P α-synuclein
    Mark A. Frasier, Mark Walzer, L. McCarthy, Debra J. Magnuson, J.M. Lee, Carola A. Haas, Philipp J. Kahle, Benjamin L. Wolozin · 2004 · Experimental Neurology
  198. A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines
    Yu, Wendou, Polepalli, Jai, Wagh, Dhananjay, Rajadas, Jayakumar, Malenka, Robert, Lu, Bingwei · 2012 · Human Molecular Genetics
  199. Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
    Garg, Sarika, Timm, Thomas, Mandelkow, Eva-Maria, Mandelkow, Eckhard, Wang, Yipeng · 2011 · Neurobiology of Aging
  200. Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis
    Pallas‐Bazarra, Noemí, Jurado‐Arjona, Jerónimo, Navarrete, Marta, Esteban, Jose A, Hernández, Félix, Ávila, Jesús, Llorens‐Martín, María · 2016 · The EMBO Journal