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Wang, W., Furneaux, H., Cheng, H., Caldwell, M. C., Hutter, D., Liu, Y., Holbrook, N. J., & Gorospe, M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.3.760-769.2000 · Cited by 539

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.Preprint

Linke, S. P., Clarkin, K., Leonardo, A. D., Tsou, A.-P., & Wahl, G. M. (1996) · Genes & Development · doi:10.1101/gad.10.8.934 · Cited by 531

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

Fiscella, M., Zhang, H., Fan, S., Sakaguchi, K., Shen, S., Mercer, W. E., Woude, G. F. V., O'Connor, P. M., & Appella, E. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6048 · Cited by 535

Oxidative stress and cell cycle checkpoint function11Both Drs. Paules and Kaufmann received their doctoral degrees in Experimental Pathology from the University of North Carolina at Chapel Hill School of Medicine (in 1984 and 1979, respectively).

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Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoproteinPreprint

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Genomic instability in Gadd45a-deficient mice

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The DNA Replication and Damage Checkpoint Pathways Induce Transcription by Inhibition of the Crt1 Repressor

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Characterization of the p53-Dependent Postmitotic Checkpoint following Spindle Disruption

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Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.Preprint

Yan, Y., Frisén, J., Lee, M., Massagué, J., & Barbacid, M. (1997) · Genes & Development · doi:10.1101/gad.11.8.973 · Cited by 491

Different telomere damage signaling pathways in human and mouse cells

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Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

Lim, S., Chen, X. L., Lim, Y., Hanson, D. A., Vo, T.-T. T., Howerton, K., Larocque, N., Fisher, S. J., Schlaepfer, D. D., & Ilić, D. (2008) · Molecular Cell · doi:10.1016/j.molcel.2007.11.031 · Cited by 502

p53 in growth control and neoplasia

Gottlieb, T. M., & Oren, M. (1996) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(95)00019-c · Cited by 483

Drosophila p53 Binds a Damage Response Element at the reaper Locus

Brodsky, M. H., Nordstrom, W., Tsang, G., Kwan, E., Rubin, G. M., & Abrams, J. (2000) · Cell · doi:10.1016/s0092-8674(00)80627-3 · Cited by 474

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

Waldman, T. A., Kinzler, K. W., & Vogelstein, B. (1995) · PubMed · Cited by 1,188

p21WAF1/CIP1 may be a tumor suppressor after all

Gartel, A. L. (2007) · Cancer Biology & Therapy · doi:10.4161/cbt.6.8.4712 · Cited by 19

p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.

Zhang, W., Grasso, L., McClain, C. D., Gambel, A. M., Cha, Y., Travali, S., Deisseroth, A., & Mercer, W. E. (1995) · PubMed · Cited by 253

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

El‐Deiry, W. S., Harper, J. W., O'Connor, P. M., Velculescu, V. E., Ce, C., Jackman, J., Pietenpol, J. A., Burrell, M., De, H., & Wang, Y. (1994) · PubMed · Cited by 2,021

p21(WAF1) Mediates Cell-Cycle Inhibition, Relevant to Cancer Suppression and Therapy

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