The DOI matches its Crossref record; 602 of the 602 references it cites were found in a registry or an index.
The importance of free radicals and catalytic metal ions in human diseases.
Abstract
The study of free radical reactions is not an isolated and esoteric branch of science. A knowledge of free radical chemistry and biochemistry is relevant to an understanding of all diseases and the mode of action of all toxins, if only because diseased or damaged tissues undergo radical reactions more readily than do normal tissues. However it does not follow that because radical reactions can be demonstrated, they are important in any particular instance. We hope that the careful techniques needed to assess the biological role of free radicals will become more widely used.
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“Fe2+ also has the potential to generate damaging reactive oxygen species (ROS) via Fenton/Haber Weiss chemistry [5]”
From Host Iron Withholding Demands Siderophore Utilization for Candida glabrata to Survive Macrophage Killing (2011) · cites this paper as [5]
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“species (ROS) via Fenton/Haber Weiss chemistry [5] and, as a”
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Metadata
- Authors
- Halliwell, B., & Gutteridge, J. M. C.
- Affiliations
- University of London (GB)
- ORCID
- Halliwell, Barry
- Venue
- Molecular Aspects of Medicine
- Publisher
- Elsevier BV
- Published
- 1985-01
- Volume
- 8
- Issue
- 2
- Pages
- 89-193
- ISSN
- 0098-2997 (ISSN-L)
- OpenAlex
- W2069471046
- Cited by
- 941
- References
- 602
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 7 · 2023: 14 · 2022: 19 · 2021: 9 · 2020: 26 · 2019: 18 · 2018: 10 · 2017: 15 · 2016: 16 · 2015: 26 · 2014: 17 · 2013: 28 · 2012: 20
- FWCI
- 5.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Aspects of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Physical Sciences › Chemistry › Organic Chemistry › Free Radicals and Antioxidants
- Keywords
- free radicals, catalytic metal ions, radical reactions, human disease, toxins, tissue damage, oxidative stress
- MeSH terms
- Aging, Autoimmune Diseases, Brain Ischemia, Copper, Coronary Disease, Disease, Physical Exertion, Free Radicals, Humans, Intestines, Iron, Ischemia, Joint Diseases, Lipid Peroxides, Malaria, Metals, Neoplasms, Nervous System Diseases, Respiratory Distress Syndrome
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