The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
Celermajer, D. S., Sorensen, K. E., Gooch, V. M., Spiegelhalter, D. J., Miller, O. I., Sullivan, I. D., Lloyd, J. K., & Deanfield, J. E. (1992) · The Lancet · doi:10.1016/0140-6736(92)93147-f · Cited by 4,742
Self-citation
Cited by
Lakatta, E. G., & Levy, D. (2003) · Circulation · doi:10.1161/01.cir.0000048892.83521.58 · Cited by 2,244
Fletcher, G. F., Ades, P. A., Kligfield, P., Arena, R., Balady, G. J., Bittner, V. A., Coke, L. A., Fleg, J. L., Forman, D. E., Gerber, T. C., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829b5b44 · Cited by 2,235
DeSouza, C. A., Shapiro, L. F., Clevenger, C. M., Dinenno, F. A., Monahan, K. D., Tanaka, H., & Seals, D. R. (2000) · Circulation · doi:10.1161/01.cir.102.12.1351 · Cited by 896
Aging and vascular endothelial function in humans
Seals, D. R., Jablonski, K. L., & Donato, A. J. (2011) · Clinical Science · doi:10.1042/cs20100476 · Cited by 725
Arterial Aging: Is It an Immutable Cardiovascular Risk Factor?
Najjar, S. S., Scuteri, A., & Lakatta, E. G. (2005) · Hypertension · doi:10.1161/01.hyp.0000177474.06749.98 · Cited by 640
The Aging Cardiovascular System
Paneni, F., Diaz Cañestro, C., Libby, P., Lüscher, T. F., & Camici, G. G. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.01.064 · Cited by 618
Ascorbic Acid Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease
Levine, G. N., Frei, B., Koulouris, S. N., Gerhard, M. D., Keaney, J. F., & Vita, J. A. (1996) · Circulation · doi:10.1161/01.cir.93.6.1107 · Cited by 582
Impaired progenitor cell activity in age-related endothelial dysfunction
Heiss, C., Keymel, S., Niesler, U., Ziemann, J., Kelm, M., & Kalka, C. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.074 · Cited by 573
Cellular and molecular biology of aging endothelial cells
Donato, A. J., Morgan, R. G., Walker, A. E., & Lesniewski, L. A. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.01.021 · Cited by 538
Kurz, D. J., Decary, S., Hong, Y., Trivier, E., Akhmedov, A., & Erusalimsky, J. D. (2004) · Journal of Cell Science · doi:10.1242/jcs.01097 · Cited by 499
Age-associated Cardiovascular Changes in Health: Impact on Cardiovascular Disease in Older Persons
Lakatta, E. G. (2002) · Heart Failure Reviews · doi:10.1023/a:1013797722156 · Cited by 445
Lobelo, F., Rohm Young, D., Sallis, R., Garber, M. D., Billinger, S. A., Duperly, J., Hutber, A., Pate, R. R., Thomas, R. J., Widlansky, M. E., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000559 · Cited by 402
Vascular endothelial senescence: from mechanisms to pathophysiology
Erusalimsky, J. D. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91353.2008 · Cited by 399
Schulman, S. P., Becker, L. C., Kass, D. A., Champion, H. C., Terrin, M. L., Forman, S., Ernst, K. V., Kelemen, M. D., Townsend, S. N., Capriotti, A., et al. (2006) · JAMA · doi:10.1001/jama.295.1.58 · Cited by 357
Eskurza, I., Monahan, K. D., Robinson, J. A., & Seals, D. R. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2003.057042 · Cited by 341
Self-citationVascular biology of ageing—Implications in hypertension
Harvey, A., Montezano, A. C., & Touyz, R. M. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.04.011 · Cited by 330
Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease
Kenjale, A. A., Ham, K. L., Stabler, T., Robbins, J. L., Johnson, J. L., VanBruggen, M., Privette, G., Yim, E., Kraus, W. E., & Allen, J. D. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00071.2011 · Cited by 316
Aging and Alzheimer's disease: comparison and associations from molecular to system level
Xia, X., Jiang, Q., McDermott, J., & Han, J. J. (2018) · Aging Cell · doi:10.1111/acel.12802 · Cited by 301
Sindler, A. L., Fleenor, B. S., Calvert, J. W., Marshall, K. D., Zigler, M. L., Lefer, D. J., & Seals, D. R. (2011) · Aging Cell · doi:10.1111/j.1474-9726.2011.00679.x · Cited by 218
“One of these is the development of vascular endothelial dysfunction, as most commonly indicated by impaired endothelium-dependent dilation (EDD) (Celermajer et al., 1994; Taddei et al., 1995; Lakatta & Levy, 2003).”
BackgroundCaloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals
Lefevre, M., Redman, L. M., Heilbronn, L. K., Smith, J. V., Martin, C. K., Rood, J. C., Greenway, F. L., Williamson, D. A., Smith, S. R., & Ravussin, E. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.05.036 · Cited by 217
Flow‐mediated dilatation in the superficial femoral artery is nitric oxide mediated in humans
Kooijman, M., Thijssen, D. H. J., De Groot, P. C. E., Bleeker, M. W. P., Van Kuppevelt, H. J. M., Green, D. J., Rongen, G. A., Smits, P., & Hopman, M. T. E. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.145722 · Cited by 207
Smith, G. I., Atherton, P., Villareal, D. T., Frimel, T. N., Rankin, D., Rennie, M. J., & Mittendorfer, B. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001875 · Cited by 168
Thijssen, D. H. J., Vos, J. B., Verseyden, C., Van Zonneveld, A. J., Smits, P., Sweep, F. C. G. J., Hopman, M. T. E., & De Boer, H. C. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00242.x · Cited by 156
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis
Carlström, M., Liu, M., Yang, T., Zollbrecht, C., Huang, L., Peleli, M., Borniquel, S., Kishikawa, H., Hezel, M., Persson, A. E. G., et al. (2015) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5481 · Cited by 130
Holder, S. M., Bruno, R. M., Shkredova, D. A., Dawson, E. A., Jones, H., Hopkins, N. D., Hopman, M. T. E., Bailey, T. G., Coombes, J. S., Askew, C. D., et al. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.15754 · Cited by 118
Allen, J. D., Stabler, T., Kenjale, A., Ham, K. L., Robbins, J. L., Duscha, B. D., Dobrosielski, D. A., & Annex, B. H. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.06.033 · Cited by 101
Nutrition and other lifestyle influences on arterial aging
LaRocca, T. J., Martens, C. R., & Seals, D. R. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2016.09.002 · Cited by 83
Benefit of Low-Fat Over Low-Carbohydrate Diet on Endothelial Health in Obesity
Phillips, S. A., Jurva, J. W., Syed, A. Q., Syed, A. Q., Kulinski, J. P., Pleuss, J., Hoffmann, R. G., & Gutterman, D. D. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.101824 · Cited by 84
Plasma nitrite response and arterial reactivity differentiate vascular health and performance
Allen, J. D., Miller, E. M., Schwark, E., Robbins, J. L., Duscha, B. D., & Annex, B. H. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.01.002 · Cited by 76
Joannides, R., Costentin, A., Iacob, M., Compagnon, P., Lahary, A., & Thuillez, C. (2002) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00209.2001 · Cited by 75
Aging, ion channel expression, and vascular function
Toro, L., Marijic, J., Nishimaru, K., Tanaka, Y., Song, M., & Stefani, E. (2002) · Vascular Pharmacology · doi:10.1016/s0306-3623(02)00128-3 · Cited by 73
Kim, S.-M., Lim, S.-M., Yoo, J.-A., Woo, M.-J., & Cho, K.-H. (2015) · Food & Function · doi:10.1039/c5fo00738k · Cited by 69
Body composition, metabolic syndrome and testosterone in ageing men
Allan, C. A., Strauss, B. J. G., & McLachlan, R. I. (2007) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901552 · Cited by 67
Dietary nitrate supplementation in cardiovascular health: an ergogenic aid or exercise therapeutic?
Woessner, M. N., McIlvenna, L. C., Ortiz de Zevallos, J., Neil, C. J., & Allen, J. D. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00414.2017 · Cited by 50
Lennon-Edwards, S., Ramick, M. G., Matthews, E. L., Brian, M. S., Farquhar, W. B., & Edwards, D. G. (2014) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2014.05.004 · Cited by 49
Impaired handgrip exercise-induced brachial artery flow-mediated dilation in young obese males
Slattery, D. J., Stuckless, T. J. R., King, T. J., & Pyke, K. E. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0459 · Cited by 22
Allan, R. B., Vun, S. V., & Spark, J. I. (2016) · International Journal of Vascular Medicine · doi:10.1155/2016/2969740 · Cited by 20
(2005) · PubMed Central · Cited by 15
Effectiveness of coaching for enhancing the health of menopausal Japanese women
Fujimoto, K. (2017) · Journal of Women & Aging · doi:10.1080/08952841.2015.1137434 · Cited by 10
Metadata
- Authors
- Celermajer, D. S., Sorensen, K. E., Spiegelhalter, D. J., Georgakopoulos, D., Robinson, J., & Deanfield, J. E.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1994-08
- Volume
- 24
- Issue
- 2
- Pages
- 471-476
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2038273086
- Cited by
- 1,335
- References
- 2
- FWCI
- 13.48
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
