The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ikuta, K., Kina, T., MacNeil, I., Uchida, N., Peault, B., Chien, Y.-H., & Weissman, I. L. (1990) · Cell · doi:10.1016/0092-8674(90)90262-d · Cited by 583
Self-citation
Cited by
Stem cells, cancer, and cancer stem cells
Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001) · Nature · doi:10.1038/35102167 · Cited by 9,738
Self-citationKiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168
Self-citationA clonogenic common myeloid progenitor that gives rise to all myeloid lineages
Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617
Self-citationIdentification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
Kondo, M., Weissman, I. L., & Akashi, K. (1997) · Cell · doi:10.1016/s0092-8674(00)80453-5 · Cited by 2,253
Self-citationA role for Wnt signalling in self-renewal of haematopoietic stem cells
Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., Willert, K., Hintz, L., Nusse, R., & Weissman, I. L. (2003) · Nature · doi:10.1038/nature01593 · Cited by 2,159
Self-citationBmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.
Park, I.-K., Qian, D., Kiel, M., Becker, M. W., Pihalja, M., Weissman, I. L., Morrison, S. J., & Clarke, M. F. (2003) · Nature · doi:10.1038/nature01587 · Cited by 1,871
Self-citationFoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress
Tothova, Z., Kollipara, R., Huntly, B. J., Lee, B. H., Castrillon, D. H., Cullen, D. E., McDowell, E. P., Lazo-Kallanian, S., Williams, I. R., Sears, C., et al. (2007) · Cell · doi:10.1016/j.cell.2007.01.003 · Cited by 1,562
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
Ito, K., Hirao, A., Arai, F., Matsuoka, S., Takubo, K., Hamaguchi, I., Nomiyama, K., Hosokawa, K., Sakurada, K., Nakagata, N., et al. (2004) · Nature · doi:10.1038/nature02989 · Cited by 1,175
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Yilmaz, Ö. H., Valdez, R., Theisen, B. K., Guo, W., Ferguson, D. O., Wu, H., & Morrison, S. J. (2006) · Nature · doi:10.1038/nature04703 · Cited by 1,113
Self-citationStem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations
Weissman, I. L., Anderson, D. J., & Gage, F. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.387 · Cited by 948
Self-citationPhysiological Migration of Hematopoietic Stem and Progenitor Cells
Wright, D. E., Wagers, A. J., Gulati, A. P., Johnson, F. L., & Weissman, I. L. (2001) · Science · doi:10.1126/science.1064081 · Cited by 933
Self-citationIn vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
Cheshier, S. H., Morrison, S. J., Liao, X., & Weissman, I. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3120 · Cited by 858
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants
Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., & Zon, L. I. (2003) · Nature Immunology · doi:10.1038/ni1007 · Cited by 800
MicroRNAs as regulatory elements in immune system logic
Mehta, A., & Baltimore, D. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.40 · Cited by 704
Passegué, E., Wagers, A. J., Giuriato, S., Anderson, W. C., & Weissman, I. L. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050967 · Cited by 646
Self-citationThe purification and characterization of fetal liver hematopoietic stem cells
Morrison, S. J., Hemmati, H. D., Wandycz, A. M., & Weissman, I. L. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.22.10302 · Cited by 611
Self-citationLong-Term Propagation of Distinct Hematopoietic Differentiation Programs In Vivo
Dykstra, B., Kent, D., Bowie, M., McCaffrey, L., Hamilton, M., Lyons, K., Lee, S.-J., Brinkman, R., & Eaves, C. (2007) · Cell Stem Cell · doi:10.1016/j.stem.2007.05.015 · Cited by 609
Clonal analysis of lineage fate in native haematopoiesis
Rodriguez-Fraticelli, A. E., Wolock, S. L., Weinreb, C. S., Panero, R., Patel, S. H., Jankovic, M., Sun, J., Calogero, R. A., Klein, A. M., & Camargo, F. D. (2018) · Nature · doi:10.1038/nature25168 · Cited by 596
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology · doi:10.1002/eji.202170126 · Cited by 531
Grimbaldeston, M. A., Chen, C.-C., Piliponsky, A. M., Tsai, M., Tam, S.-Y., & Galli, S. J. (2005) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)62055-x · Cited by 525
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
Bröske, A.-M., Vockentanz, L., Kharazi, S., Huska, M. R., Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., et al. (2009) · Nature Genetics · doi:10.1038/ng.463 · Cited by 478
Frenette, P. S., Pinho, S., Lucas, D., & Scheiermann, C. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-095919 · Cited by 462
Bmi1, stem cells, and senescence regulation
Park, I.-K., Morrison, S. J., & Clarke, M. F. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420800 · Cited by 495
Self-citationMyeloid or Lymphoid Promiscuity as a Critical Step in Hematopoietic Lineage Commitment
Miyamoto, T., Iwasaki, H., Reizis, B., Ye, M., Graf, T., Weissman, I. L., & Akashi, K. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00201-0 · Cited by 415
Self-citationMyeloid Lineage Commitment from the Hematopoietic Stem Cell
Iwasaki, H., & Akashi, K. (2007) · Immunity · doi:10.1016/j.immuni.2007.06.004 · Cited by 394
Telomerase Activity in Hematopoietic Cells Is Associated with Self-Renewal Potential
Morrison, S. J., Prowse, K. R., Ho, P., & Weissman, I. L. (1996) · Immunity · doi:10.1016/s1074-7613(00)80316-7 · Cited by 394
Self-citationPopulation snapshots predict early haematopoietic and erythroid hierarchies
Tusi, B. K., Wolock, S. L., Weinreb, C., Hwang, Y., Hidalgo, D., Zilionis, R., Waisman, A., Huh, J. R., Klein, A. M., & Socolovsky, M. (2018) · Nature · doi:10.1038/nature25741 · Cited by 384
Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals
Sawai, C. M., Babovic, S., Upadhaya, S., Knapp, D. J. H. F., Lavin, Y., Lau, C. M., Goloborodko, A., Feng, J., Fujisaki, J., Ding, L., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.08.007 · Cited by 381
“…activity in the BM of normal adult mice is contained in a small subset of Lineage marker (Lin)− Sca-1+ c-Kit+ (LSK) cells (Ikuta and Weissman, 1992; Morrison and Weissman, 1994) that express high levels of CD150 (Slamf1) and endothelial protein C receptor (EPCR) but low levels of CD135 (Flt3),…”
InfluentialGiladi, A., Paul, F., Herzog, Y., Lubling, Y., Weiner, A., Yofe, I., Jaitin, D., Cabezas-Wallscheid, N., Dress, R., Ginhoux, F., et al. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0121-4 · Cited by 366
Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche
Chen, J. Y., Miyanishi, M., Wang, S. K., Yamazaki, S., Sinha, R., Kao, K. S., Seita, J., Sahoo, D., Nakauchi, H., & Weissman, I. L. (2016) · Nature · doi:10.1038/nature16943 · Cited by 345
Self-citationCDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells
Laurenti, E., Frelin, C., Xie, S., Ferrari, R., Dunant, C. F., Zandi, S., Neumann, A., Plumb, I., Doulatov, S., Chen, J., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2015.01.017 · Cited by 342
Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells
Maillard, I., Koch, U., Dumortier, A., Shestova, O., Xu, L., Sai, H., Pross, S. E., Aster, J. C., Bhandoola, A., Radtke, F., et al. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.02.011 · Cited by 317
Arinobu, Y., Mizuno, S.-I., Chong, Y., Shigematsu, H., Iino, T., Iwasaki, H., Graf, T., Mayfield, R., Chan, S., Kastner, P., et al. (2007) · Cell Stem Cell · doi:10.1016/j.stem.2007.07.004 · Cited by 309
Min, I. M., Pietramaggiori, G., Kim, F. S., Passegué, E., Stevenson, K. E., & Wagers, A. J. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.01.015 · Cited by 305
AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
Juntilla, M. M., Patil, V. D., Calamito, M., Joshi, R. P., Birnbaum, M. J., & Koretzky, G. A. (2010) · Blood · doi:10.1182/blood-2009-09-241000 · Cited by 284
Chaperone-mediated autophagy sustains haematopoietic stem-cell function
Dong, S., Wang, Q., Kao, Y.-R., Diaz, A., Tasset, I., Kaushik, S., Thiruthuvanathan, V., Zintiridou, A., Nieves, E., Dzieciatkowska, M., et al. (2021) · Nature · doi:10.1038/s41586-020-03129-z · Cited by 275
Scott, E. W., Fisher, R. C., Olson, M. C., Kehrli, E. W., Simon, M. C., & Singh, H. (1997) · Immunity · doi:10.1016/s1074-7613(00)80287-3 · Cited by 270
Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
Takeda, K., Aguila, H. L., Parikh, N. S., Li, X., Lamothe, K., Duan, L.-J., Takeda, H., Lee, F. S., & Fong, G.-H. (2008) · Blood · doi:10.1182/blood-2007-09-114561 · Cited by 263
The aging of lympho-hematopoietic stem cells
Geiger, H., & Van Zant, G. (2002) · Nature Immunology · doi:10.1038/ni0402-329 · Cited by 233
Functional antagonism of the polycomb-group genes eed and Bmi1 in hemopoietic cell proliferation
Lessard, J., Schumacher, A., Thorsteinsdottir, U., van Lohuizen, M., Magnuson, T., & Sauvageau, G. (1999) · Genes & Development · doi:10.1101/gad.13.20.2691 · Cited by 219
Intermediate-Term Hematopoietic Stem Cells with Extended but Time-Limited Reconstitution Potential
Benveniste, P., Frelin, C., Janmohamed, S., Barbara, M., Herrington, R., Hyam, D., & Iscove, N. N. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2009.11.014 · Cited by 216
Wright, D. E., Cheshier, S. H., Wagers, A. J., Randall, T. D., Christensen, J. L., & Weissman, I. L. (2001) · Blood · doi:10.1182/blood.v97.8.2278 · Cited by 208
Self-citationGöthert, J. R., Gustin, S. E., Hall, M. A., Green, A. R., Göttgens, B., Izon, D. J., & Begley, C. G. (2005) · Blood · doi:10.1182/blood-2004-08-3037 · Cited by 203
Hematopoietic Stem Cells and Their Roles in Tissue Regeneration
Lee, J. Y., & Hong, S.-H. (2020) · International Journal of Stem Cells · doi:10.15283/ijsc19127 · Cited by 165
Unraveling Hematopoiesis through the Lens of Genomics
Liggett, L. A., & Sankaran, V. G. (2020) · Cell · doi:10.1016/j.cell.2020.08.030 · Cited by 163
Generation of mTert -GFP mice as a model to identify and study tissue progenitor cells
Breault, D. T., Min, I. M., Carlone, D. L., Farilla, L. G., Ambruzs, D. M., Henderson, D. E., Algra, S., Montgomery, R. K., Wagers, A. J., & Hole, N. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804800105 · Cited by 143
Rodriguez, S., Chora, A., Goumnerov, B., Mumaw, C., Goebel, W. S., Fernandez, L., Baydoun, H., HogenEsch, H., Dombkowski, D. M., Karlewicz, C. A., et al. (2009) · Blood · doi:10.1182/blood-2009-04-214916 · Cited by 135
Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells
Forsberg, E. C., Passegué, E., Prohaska, S. S., Wagers, A. J., Koeva, M., Stuart, J. M., & Weissman, I. L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008785 · Cited by 127
Self-citationSun, W., & Downing, J. R. (2004) · Blood · doi:10.1182/blood-2003-12-4349 · Cited by 118
Epigenetic regulation of aging stem cells
Pollina, E. A., & Brunet, A. (2011) · Oncogene · doi:10.1038/onc.2011.45 · Cited by 111
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance
Perry, S. S., Zhao, Y., Nie, L., Cochrane, S. W., Huang, Z., & Sun, X.-H. (2007) · Blood · doi:10.1182/blood-2007-01-069914 · Cited by 100
Bryder, D., Ramsfjell, V., Dybedal, I., Theilgaard-Mönch, K., Högerkorp, C.-M., Adolfsson, J., Borge, O. J., & Jacobsen, S. E. W. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.7.941 · Cited by 98
Kim, H.-G., de Guzman, C. G., Swindle, C. S., Cotta, C. V., Gartland, L., Scott, E. W., & Klug, C. A. (2004) · Blood · doi:10.1182/blood-2002-08-2425 · Cited by 75
Chu, S. H., Heiser, D., Li, L., Kaplan, I., Collector, M., Huso, D., Sharkis, S. J., Civin, C., & Small, D. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.05.027 · Cited by 79
Is PU.1 a dosage-sensitive regulator of haemopoietic lineage commitment and leukaemogenesis?
Dakic, A., Wu, L., & Nutt, S. L. (2007) · Trends in Immunology · doi:10.1016/j.it.2007.01.006 · Cited by 72
Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development
McDermott, S. P., Ranheim, E. A., Leatherberry, V. S., Khwaja, S. S., Klos, K. S., & Alexander, C. M. (2007) · Oncogene · doi:10.1038/sj.onc.1209930 · Cited by 61
Susek, K. H., Korpos, E., Huppert, J., Wu, C., Savelyeva, I., Rosenbauer, F., Müller-Tidow, C., Koschmieder, S., & Sorokin, L. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.01.007 · Cited by 58
Homeodomain Transcription Factor Meis1 Is a Critical Regulator of Adult Bone Marrow Hematopoiesis
Ariki, R., Morikawa, S., Mabuchi, Y., Suzuki, S., Nakatake, M., Yoshioka, K., Hidano, S., Nakauchi, H., Matsuzaki, Y., Nakamura, T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087646 · Cited by 53
Metadata
- Authors
- Morrison, S. J., & Weissman, I. L.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 1994-11
- Volume
- 1
- Issue
- 8
- Pages
- 661-673
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W1995286997
- Cited by
- 1,115
- References
- 1
- FWCI
- 8.86
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.