The DOI matches its Crossref record; 429 of the 429 references it cites were found in a registry or an index.
Health Consequences of Circadian Disruption in Humans and Animal Models
Abstract
Daily rhythms in behavior and physiology are programmed by a hierarchical collection of biological clocks located throughout the brain and body, known as the circadian system. Mounting evidence indicates that disruption of circadian regulation is associated with a wide variety of adverse health consequences, including increased risk for premature death, cancer, metabolic syndrome, cardiovascular dysfunction, immune dysregulation, reproductive problems, mood disorders, and learning deficits. Here we review the evidence for the pervasive effects of circadian disruption in humans and animal models, drawing from both environmental and genetic studies, and identify questions for future research.
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“Circadian oscillations are ubiquitous in cells throughout the brain and body and their coordinated daily activity is essential for normal health1–3.”
From Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice (2017) · cites this paper as [2]
In the citing paper
“However, when circadian disruptions are chronic, as in shift work or frequent travel across time zones, long term physiological and neurological health deteriorate2, 5.”
From Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice (2017) · cites this paper as [2]
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Metadata
- Authors
- Evans, J. A., & Davidson, A. J.
- Affiliations
- Morehouse School of Medicine (US)
- Venue
- Progress in Molecular Biology and Translational Science
- Publisher
- Elsevier
- Published
- 2013
- Volume
- 119
- Pages
- 283-323
- ISSN
- 1877-1173 (ISSN-L)
- OpenAlex
- W31275902
- Cited by
- 291
- References
- 429
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 12 · 2023: 23 · 2022: 29 · 2021: 24 · 2020: 44 · 2019: 26 · 2018: 28 · 2017: 19 · 2016: 22 · 2015: 31 · 2014: 13
- FWCI
- 13.94
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Progress in molecular biology and translational science (publishedVersion)
- PubMed (publishedVersion)
- e-Publications@Marquette (Marquette University) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Physical Sciences › Environmental Science › Global and Planetary Change › Impact of Light on Environment and Health
- Keywords
- circadian rhythm disruption, circadian system, biological clock, health effects, cancer risk, metabolic syndrome, cardiovascular dysfunction, immune dysregulation, reproductive disorders, mood disorders, learning deficits, premature mortality, genetic and environmental factors
- MeSH terms
- Animals, Circadian Rhythm, Humans, Models, Animal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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