The Circadian Clock and Human Health

Two-Process Model of Sleep Regulation

Binder, M. D., Hirokawa, N., & Windhorst, U. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_6166 · Cited by 3,895 · see citing works

Life between Clocks: Daily Temporal Patterns of Human Chronotypes

Roenneberg, T., Wirz-Justice, A., & Merrow, M. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730402239679 · Cited by 2,662 · see citing works

Social Jetlag: Misalignment of Biological and Social Time

Wittmann, M., Dinich, J., Merrow, M., & Roenneberg, T. (2006) · Chronobiology International · doi:10.1080/07420520500545979 · Cited by 2,625 · see citing works

Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite

Spiegel, K., Tasali, E., Penev, P., & Cauter, E. V. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-141-11-200412070-00008 · Cited by 2,459 · see citing works

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421 · see citing works

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes & Development · doi:10.1101/gad.183500 · Cited by 2,394 · see citing works

Adverse metabolic and cardiovascular consequences of circadian misalignment

Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808180106 · Cited by 2,351 · see citing works

A circadian gene expression atlas in mammals: Implications for biology and medicine

Zhang, R., Lahens, N. F., Ballance, H. I., Hughes, M. E., & Hogenesch, J. B. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408886111 · Cited by 2,304 · see citing works

Clock Mutants of Drosophila melanogaster

Konopka, R. J., & Benzer, S. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.9.2112 · Cited by 2,287 · see citing works

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

Hatori, M., Vollmers, C., Zarrinpar, A., DiTacchio, L., Bushong, E. A., Gill, S., Leblanc, M., Chaix, A., Joens, M., Fitzpatrick, J. A. J., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.019 · Cited by 1,986 · see citing works

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907 · see citing works

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859 · see citing works

Entrainment of the circadian clock in the liver by feeding

Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800 · see citing works

Stability, precision, and near-24-hour period of the human circadian pacemaker

Czeisler, C. A., Duffy, J. F., Shanahan, T. L., Brown, E. N., Mitchell, J. F., Rimmer, D. W., Ronda, J. M., Silva, E. J., Allan, J. S., Emens, J. S., et al. (1999) · Science · doi:10.1126/science.284.5423.2177 · Cited by 1,705 · see citing works

A marker for the end of adolescence

Roenneberg, T., Kuehnle, T., Pramstaller, P. P., Ricken, J., Havel, M., Guth, A., & Merrow, M. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.039 · Cited by 1,585 · see citing works

Circadian rhythms from multiple oscillators: lessons from diverse organisms

Bell‐Pedersen, D., Cassone, V. M., Earnest, D. J., Golden, S. S., Hardin, P. E., Thomas, T. L., & Zoran, M. J. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1633 · Cited by 1,481 · see citing works

Timing of human sleep: recovery process gated by a circadian pacemaker

Daan, S., Beersma, D. G. M., & Borbély, A. A. (1984) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1984.246.2.r161 · Cited by 1,424 · see citing works

Social jetlag and obesity

Roenneberg, T., Allebrandt, K. V., Merrow, M., & Vetter, C. (2012) · Current Biology · doi:10.1016/j.cub.2012.03.038 · Cited by 1,407 · see citing works

The metabolic consequences of sleep deprivation

Knutson, K. L., Spiegel, K., Penev, P., & Van Cauter, E. (2007) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2007.01.002 · Cited by 1,365 · see citing works

Health disorders of shift workers

Knutsson, A. (2003) · Occupational Medicine · doi:10.1093/occmed/kqg048 · Cited by 1,218 · see citing works

Circadian control of the immune system

Scheiermann, C., Kunisaki, Y., & Frenette, P. S. (2013) · Nature Reviews Immunology · doi:10.1038/nri3386 · Cited by 1,135 · see citing works

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195262 · Cited by 917 · see citing works

The Meter of Metabolism

Green, C. B., Takahashi, J. S., & Bass, J. (2008) · Cell · doi:10.1016/j.cell.2008.08.022 · Cited by 902 · see citing works

Time for food: the intimate interplay between nutrition, metabolism, and the circadian clock

Asher, G., & Sassone-Corsi, P. (2015) · Cell · doi:10.1016/j.cell.2015.03.015 · Cited by 844 · see citing works

A circadian clock in macrophages controls inflammatory immune responses

Keller, M., Mazuch, J., Abraham, U., Eom, G. D., Herzog, E. D., Volk, H.-D., Kramer, A., & Maier, B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906361106 · Cited by 843 · see citing works

Night-Shift Work and Risk of Colorectal Cancer in the Nurses' Health Study

Schernhammer, E. S., Laden, F., Speizer, F. E., Willett, W. C., Hunter, D. J., Kawachi, I. I., Fuchs, C. S., & Colditz, G. A. (2003) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/95.11.825 · Cited by 837 · see citing works

Effect of Bright Light and Melatonin on Cognitive and Noncognitive Function in Elderly Residents of Group Care Facilities: A Randomized Controlled Trial

Riemersma-van der Lek, R. F. (2008) · JAMA · doi:10.1001/jama.299.22.2642 · Cited by 803 · see citing works

Regulation of adolescent sleep: Implications for behavior

CARSKADON, M. A., ACEBO, C., & JENNI, O. G. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1308.032 · Cited by 792 · see citing works

Entrainment of the Human Circadian Clock to the Natural Light-Dark Cycle

Wright, K. P., McHill, A. W., Birks, B. R., Griffin, B. R., Rusterholz, T., & Chinoy, E. D. (2013) · Current Biology · doi:10.1016/j.cub.2013.06.039 · Cited by 783 · see citing works

Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons

Aton, S. J., Colwell, C. S., Harmar, A. J., Waschek, J. A., & Herzog, E. D. (2005) · Nature Neuroscience · doi:10.1038/nn1419 · Cited by 764 · see citing works

The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei

Harmar, A. J., Marston, H. M., Shen, S., Spratt, C., West, K. M., Sheward, W. J., Morrison, C. F., Dorin, J. R., Piggins, H. D., Reubi, J.-C., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)00736-5 · Cited by 549 · see citing works

Circadian Clocks in the Immune System

Labrecque, N., & Cermakian, N. (2015) · Journal of Biological Rhythms · doi:10.1177/0748730415577723 · Cited by 468 · see citing works

Effects of Experimental Sleep Restriction on Weight Gain, Caloric Intake, and Meal Timing in Healthy Adults

Spaeth, A. M., Dinges, D. F., & Goel, N. (2013) · Sleep · doi:10.5665/sleep.2792 · Cited by 457 · see citing works

Die relative Koordination

Holst, E. V. (1939) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/bf02322567 · Cited by 454 · see citing works

Social jetlag, chronotype, and cardiometabolic risk

Wong, P. M., Hasler, B. P., Kamarck, T. W., Muldoon, M. F., & Manuck, S. B. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-2923 · Cited by 444 · see citing works

Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015

Auger, R. R., Burgess, H. J., Emens, J. S., Deriy, L. V., Thomas, S. M., & Sharkey, K. M. (2015) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.5100 · Cited by 437 · see citing works

Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease

Morton, A. J., Wood, N. I., Hastings, M. H., Hurelbrink, C., Barker, R. A., & Maywood, E. S. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3842-04.2005 · Cited by 403 · see citing works

Short-Wavelength Light Sensitivity of Circadian, Pupillary, and Visual Awareness in Humans Lacking an Outer Retina

Zaidi, F. H., Hull, J. T., Peirson, S. N., Wulff, K., Aeschbach, D., Gooley, J. J., Brainard, G. C., Gregory-Evans, K., Rizzo, J. F., Czeisler, C. A., et al. (2007) · Current Biology · doi:10.1016/j.cub.2007.11.034 · Cited by 364 · see citing works

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

The Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC), Bonnefond, A., Clément, N., Fawcett, K., Yengo, L., Vaillant, E., Guillaume, J.-L., Dechaume, A., Payne, F., Roussel, R., et al. (2012) · Nature Genetics · doi:10.1038/ng.1053 · Cited by 363 · see citing works

The Human Circadian Clock's Seasonal Adjustment Is Disrupted by Daylight Saving Time

Kantermann, T., Juda, M., Merrow, M. W., & Roenneberg, T. (2007) · Current Biology · doi:10.1016/j.cub.2007.10.025 · Cited by 357 · see citing works

ELF3 Modulates Resetting of the Circadian Clock in Arabidopsis

Covington, M. F., Panda, S., Liu, X. L., et al. (2001) · The Plant Cell · doi:10.1105/tpc.000561 · Cited by 327 · see citing works

Relationship between Melatonin Rhythms and Visual Loss in the Blind

Lockley, S. W., Skene, D. J., Arendt, J., Tabandeh, H., Bird, A. C., & Defrance, R. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.11.4355 · Cited by 312 · see citing works

Circadian Clock Mutants of Cyanobacteria

Kondo, T., Tsinoremas, N. F., Golden, S. S., Johnson, C. H., Kutsuna, S., & Ishiura, M. (1994) · Science · doi:10.1126/science.7973706 · Cited by 308 · see citing works

Aligning Work and Circadian Time in Shift Workers Improves Sleep and Reduces Circadian Disruption

Vetter, C., Fischer, D. R., Matera, J. L., & Roenneberg, T. (2015) · Current Biology · doi:10.1016/j.cub.2015.01.064 · Cited by 305 · see citing works

Temporal Coordination of Physiologic FunctionPreprint

Halberg, F. (1960) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1960.025.01.031 · Cited by 298 · see citing works

Health Consequences of Circadian Disruption in Humans and Animal Models

Evans, J. A., & Davidson, A. J. (2013) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-396971-2.00010-5 · Cited by 291 · see citing works

Chronotherapeutics (light and wake therapy) in affective disorders

WIRZ-JUSTICE, A., BENEDETTI, F., BERGER, M., LAM, R. W., MARTINY, K., TERMAN, M., & WU, J. C. (2005) · Psychological Medicine · doi:10.1017/s003329170500437x · Cited by 291 · see citing works

Chronotype is independently associated with glycemic control in type 2 diabetes

Reutrakul, S., Hood, M. M., Crowley, S. J., Morgan, M. K., Teodori, M., Knutson, K. L., & Van Cauter, E. (2013) · Diabetes Care · doi:10.2337/dc12-2697 · Cited by 285 · see citing works

Effects of caffeine on the human circadian clock in vivo and in vitro

Burke, T. M., Markwald, R. R., McHill, A. W., Chinoy, E. D., Snider, J. A., Bessman, S. C., Jung, C. M., O’Neill, J. S., & Wright, K. P. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac5125 · Cited by 283 · see citing works

Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag

Kießling, S., Gregor Eichele, C., & Oster, H. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41192 · Cited by 273 · see citing works

Incidence of breast cancer in Norwegian female radio and telegraph operators

Tynes, T., Hannevik, M., Andersen, A., Vistnes, A. I., & Haldorsen, T. (1996) · Cancer Causes & Control · doi:10.1007/bf00051295 · Cited by 261 · see citing works

Seasonal Encoding by the Circadian Pacemaker of the SCN

vanderLeest, H. T., Houben, T., Michel, S. H., Deboer, T., Albus, H., Vansteensel, M. J., Block, G. D., & Meijer, J. H. (2007) · Current Biology · doi:10.1016/j.cub.2007.01.048 · Cited by 253 · see citing works

Metabolic effects of sleep disruption, links to obesity and diabetes

Nedeltcheva, A. V., & Scheer, F. A. J. L. (2014) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/med.0000000000000082 · Cited by 249 · see citing works

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.

Aronson, B. D., Johnson, K. A., & Dunlap, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7683 · Cited by 226 · see citing works

Sleep and Circadian Rhythm Disruption in Social Jetlag and Mental Illness

Foster, R. G., Peirson, S. N., Wulff, K., Winnebeck, E., Vetter, C., & Roenneberg, T. (2013) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-396971-2.00011-7 · Cited by 224 · see citing works

Impact of nutrients on circadian rhythmicity

Oosterman, J. E., Kalsbeek, A., la Fleur, S. E., & Belsham, D. D. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00322.2014 · Cited by 221 · see citing works

Light and the Human Circadian Clock

Roenneberg, T., Kantermann, T., Juda, M., Vetter, C., & Allebrandt, K. V. (2013) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25950-0_13 · Cited by 220 · see citing works

The Munich ChronoType Questionnaire for Shift-Workers (MCTQ Shift )

Juda, M., Vetter, C., & Roenneberg, T. (2013) · Journal of Biological Rhythms · doi:10.1177/0748730412475041 · Cited by 204 · see citing works

ELF3 Modulates Resetting of the Circadian Clock in Arabidopsis

Covington, M. F. (2001) · The Plant Cell · doi:10.1105/tpc.13.6.1305 · Cited by 204 · see citing works

Visual impairment and circadiam rhythm disorders

Lockley, S. W., Arendt, J., & Skene, D. J. (2007) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2007.9.3/slockley · Cited by 196 · see citing works

Mismatch of Sleep and Work Timing and Risk of Type 2 Diabetes

Vetter, C., Devore, E. E., Ramin, C. A., Speizer, F. E., Willett, W. C., & Schernhammer, E. S. (2015) · Diabetes Care · doi:10.2337/dc15-0302 · Cited by 195 · see citing works

In Vivo Monitoring of Peripheral Circadian Clocks in the Mouse

Tahara, Y., Kuroda, H., Saito, K., Nakajima, Y., Kubo, Y., Ohnishi, N., Seo, Y., Otsuka, M., Fuse, Y., Ohura, Y., et al. (2012) · Current Biology · doi:10.1016/j.cub.2012.04.009 · Cited by 181 · see citing works

Suprachiasmatic Regulation of Circadian Rhythms of Gene Expression in Hamster Peripheral Organs: Effects of Transplanting the Pacemaker

Guo, H., Brewer, J. M., Lehman, M. N., & Bittman, E. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4676-05.2006 · Cited by 180 · see citing works

The Network of Time: Understanding the Molecular Circadian System

Roenneberg, T., & Merrow, M. W. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00124-6 · Cited by 180 · see citing works

Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant

Izumo, M., Pejchal, M., Schook, A. C., Lange, R. P., Walisser, J. A., Sato, T., Wang, X., Bradfield, C. A., & Takahashi, J. S. (2014) · eLife · doi:10.7554/elife.04617 · Cited by 180 · see citing works

Human Activity and Rest In Situ

Roenneberg, T., Keller, L. K., Fischer, D., Matera, J. L., Vetter, C., & Winnebeck, E. C. (2015) · Methods in Enzymology · doi:10.1016/bs.mie.2014.11.028 · Cited by 175 · see citing works

Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice

Van Dycke, K. C. G., Rodenburg, W., van Oostrom, C. T. M., van Kerkhof, L. W. M., Pennings, J. L. A., Roenneberg, T., van Steeg, H., & van der Horst, G. T. J. (2015) · Current Biology · doi:10.1016/j.cub.2015.06.012 · Cited by 170 · see citing works

Light at Night, Shiftwork, and Breast Cancer Risk

Hansen, J. (2001) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/93.20.1513 · Cited by 168 · see citing works

Consequences of Circadian Disruption on Cardiometabolic Health

Reutrakul, S., & Knutson, K. L. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.07.005 · Cited by 163 · see citing works

Circadian Disruption, Sleep Loss, and Prostate Cancer Risk: A Systematic Review of Epidemiologic Studies

Sigurdardottir, L. G., Valdimarsdottir, U. A., Fall, K., Rider, J. R., Lockley, S. W., Schernhammer, E., & Mucci, L. A. (2012) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-12-0116 · Cited by 162 · see citing works

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

González, S., Moreno‐Delgado, D., Moreno, E., et al. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001347 · Cited by 160 · see citing works

The Circadian System in Alzheimer’s Disease: Disturbances, Mechanisms, and Opportunities

Coogan, A. N., Schutová, B., Husung, S., Furczyk, K., Baune, B. T., Kropp, P. A., Häßler, F., & Thome, J. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.11.021 · Cited by 158 · see citing works

Ras-Mediated Deregulation of the Circadian Clock in Cancer

Relógio, A., Thomas, P. E., Medina-Pérez, P., Reischl, S., Bervoets, S., Gloc, E., Riemer, P., Mang‐Fatehi, S., Maier, B., Schäfer, R., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004338 · Cited by 146 · see citing works

The regulation of neuroendocrine function: Timing is everything

Kriegsfeld, L. J., & Silver, R. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.12.011 · Cited by 146 · see citing works

Interindividual Variation in Sleep Duration and Its Association With Sleep Debt in Young Adults

Klerman, E. B., & Dijk, D. (2005) · SLEEP · doi:10.1093/sleep/28.10.1253 · Cited by 138 · see citing works

The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock

Husse, J., Leliavski, A., Tsang, A. H., Oster, H., & Eichele, G. (2014) · The FASEB Journal · doi:10.1096/fj.14-256594 · Cited by 133 · see citing works

Shift Work and Endocrine Disorders

Ulhôa, M. A., Marqueze, E. C., Burgos, L. G. A., & Moreno, C. R. D. C. (2015) · International Journal of Endocrinology · doi:10.1155/2015/826249 · Cited by 127 · see citing works

β₁-adrenergic antagonists and melatonin reset the clock and restore sleep in a circadian disorder, Smith-Magenis syndrome

De Leersnyder, H., Bresson, J. L., de Blois, M.-C., Souberbielle, J.-C., Mogenet, A., Delhotal-Landes, B., Salefranque, F., & Munnich, A. (2003) · Journal of Medical Genetics · doi:10.1136/jmg.40.1.74 · Cited by 126 · see citing works

Glucocorticoids entrain molecular clock components in human peripheral cells

Cuesta, M., Cermakian, N., & Boivin, D. B. (2014) · The FASEB Journal · doi:10.1096/fj.14-265686 · Cited by 125 · see citing works

Effects of restricted daily feeding on freerunning circadian rhythms in rats

Honma, K., von Goetz, C., & Aschoff, J. (1983) · Physiology & Behavior · doi:10.1016/0031-9384(83)90256-1 · Cited by 124 · see citing works

Circadian Rhythm Disorders and Melatonin Production in 127 Blind Women with and without Light Perception

Flynn‐Evans, E. E., Tabandeh, H., Skene, D. J., & Lockley, S. W. (2014) · Journal of Biological Rhythms · doi:10.1177/0748730414536852 · Cited by 121 · see citing works

Circadian Rhythm Sleep-Wake Disorders

Abbott, S. M., Reid, K. J., & Zee, P. C. (2015) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2015.07.012 · Cited by 109 · see citing works

Evaluating the links between schizophrenia and sleep and circadian rhythm disruption

Pritchett, D., Wulff, K., Oliver, P. L., Bannerman, D. M., Davies, K. E., Harrison, P. J., Peirson, S. N., & Foster, F. (2012) · Journal of Neural Transmission · doi:10.1007/s00702-012-0817-8 · Cited by 107 · see citing works

Daily regulation of hormone profiles.

Kalsbeek, A., & Fliers, E. (2013) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-25950-0_8 · Cited by 91 · see citing works

Persistent Cell-Autonomous Circadian Oscillations in Fibroblasts Revealed by Six-Week Single-Cell Imaging of PER2::LUC Bioluminescence

Leise, T., Wang, C. W., Gitis, P. J., & Welsh, D. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033334 · Cited by 89 · see citing works

Circadian Rhythms and Mood Disorders: Are the Phenomena and Mechanisms Causally Related?

Bechtel, W. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00118 · Cited by 82 · see citing works

A schizophrenic patient with an arrhythmic circadian rest-activity cycle

Wirz-Justice, A., Cajochen, C., & Nussbaum, P. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(97)00117-0 · Cited by 78 · see citing works

Resting metabolic rate varies by race and by sleep duration

Spaeth, A. M., Dinges, D. F., & Goel, N. (2015) · Obesity · doi:10.1002/oby.21198 · Cited by 78 · see citing works

Total visual blindness is protective against breast cancer

Flynn‐Evans, E. E., Stevens, R. G., Tabandeh, H., Schernhammer, E. S., & Lockley, S. W. (2009) · Cancer Causes & Control · doi:10.1007/s10552-009-9405-0 · Cited by 77 · see citing works

Increased Daytime Sleepiness in Patients with Childhood Craniopharyngioma and Hypothalamic Tumor Involvement: Review of the Literature and Perspectives

Müller, H. L. (2010) · International Journal of Endocrinology · doi:10.1155/2010/519607 · Cited by 77 · see citing works

Non–24-Hour Sleep–Wake Rhythm Disorder in Sighted and Blind Patients

Uchiyama, M., & Lockley, S. W. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.07.006 · Cited by 77 · see citing works

Consequences of Circadian Disruption on Neurologic Health

Videnović, A., & Zee, P. C. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.08.004 · Cited by 75 · see citing works

Incidence of Myocardial Infarction With Shifts to and From Daylight Savings Time

Jiddou, M. R., Pica, M., Boura, J., Qu, L., & Franklin, B. A. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.11.010 · Cited by 72 · see citing works

Non-24-hour sleep–wake syndrome following a car accident

Boivin, D. B., James, F. O., Santo, J. B., Çalıyurt, O., & Chalk, C. (2003) · Neurology · doi:10.1212/01.wnl.0000061482.24750.7c · Cited by 68 · see citing works

An association between clock genes and clock‐controlled cell cycle genes in murine colorectal tumors

Soták, M., Polidarová, L., Ergang, P., Sumová, A., & Pácha, J. (2012) · International Journal of Cancer · doi:10.1002/ijc.27760 · Cited by 64 · see citing works

Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney

Huisman, S. A., Oklejewicz, M., Ahmadi, A. R., Tamanini, F., IJzermans, J. N. M., van der Horst, G. T. J., & de Bruin, R. W. F. (2014) · International Journal of Cancer · doi:10.1002/ijc.29089 · Cited by 64 · see citing works

Shift work and hypertension: Prevalence and analysis of disease pathways in a German car manufacturing company

Ohlander, J., Keskin, M., Stork, J., & Radon, K. (2015) · American Journal of Industrial Medicine · doi:10.1002/ajim.22437 · Cited by 53 · see citing works

Relative Coordination to Unknown “Weak Zeitgebers” in Free-Running Blind Individuals

Emens, J. S., Lewy, A. J., Lefler, B. J., & Sack, R. L. (2005) · Journal of Biological Rhythms · doi:10.1177/0748730404273294 · Cited by 48 · see citing works

Circadian rhythm sleep disorders: lessons from the blind

Sack, R. L., & Lewy, A. J. (2001) · Sleep Medicine Reviews · doi:10.1053/smrv.2000.0147 · Cited by 45 · see citing works

Circadian rhythms of cellular immunity in rheumatoid arthritis: a hypothesis-generating study.

Spies, C. M., Hoff, P., Mazuch, J., et al. (2015) · PubMed · Cited by 45 · see citing works

Are daylight saving time transitions associated with changes in myocardial infarction incidence? Results from the German MONICA/KORA Myocardial Infarction Registry

Kirchberger, I., Wolf, K., Heier, M., Kuch, B., von Scheidt, W., Peters, A., & Meisinger, C. (2015) · BMC Public Health · doi:10.1186/s12889-015-2124-4 · Cited by 39 · see citing works

Internal time: chronotypes, social jet lag, and why you're so tired

(2012) · Choice Reviews Online · doi:10.5860/choice.50-0871 · Cited by 35 · see citing works

The molecular clock as a metabolic rheostat

Perelis, M., Ramsey, K. M., & Bass, J. T. (2015) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12521 · Cited by 35 · see citing works

Regulation of Circadian and Acute Activity Levels by the Murine Suprachiasmatic Nuclei

Houben, T., Coomans, C. P., & Meijer, J. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110172 · Cited by 31 · see citing works

Genetics of Human Sleep Behavioral Phenotypes

Hsu, P.-K., Ptáček, L. J., & Fu, Y.-H. (2015) · Methods in Enzymology · doi:10.1016/bs.mie.2014.10.046 · Cited by 29 · see citing works

Scheduled wheel access during daytime: A method for studying conflicting zeitgebers

Dallmann, R., & Mrosovsky, N. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.04.022 · Cited by 28 · see citing works

Phenotyping of Neurobehavioral Vulnerability to Circadian Phase During Sleep Loss

Goel, N., Basner, M., & Dinges, D. F. (2014) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2014.10.024 · Cited by 27 · see citing works

Metabolic effects of bariatric surgery in mouse models of circadian disruption

Arble, D. M., Sandoval, D. A., Turek, F. W., Woods, S. C., & Seeley, R. J. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.54 · Cited by 24 · see citing works

Circadian Dysrhythmias in the Intensive Care Unit

Billings, M. E., & Watson, N. F. (2015) · Critical Care Clinics · doi:10.1016/j.ccc.2015.03.006 · Cited by 21 · see citing works

Apparent phase-shifts of circadian rhythms (masking effects) during rapid shift rotation

Vokac, Z., Magnus, P. M., Jebens, E., & Gundersen, N. (1981) · International Archives of Occupational and Environmental Health · doi:10.1007/bf00380809 · Cited by 20 · see citing works

Global Profiling of the Circadian Transcriptome Using Microarrays

Hsu, P. Y., & Harmer, S. L. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-0700-7_3 · Cited by 20 · see citing works

Rest-Activity Cycle and Melatonin Rhythm in Blind Free-Runners Have Similar Periods

Emens, J. S., Lewy, A. J., Laurie, A., & Songer, J. B. (2010) · Journal of Biological Rhythms · doi:10.1177/0748730410379080 · Cited by 16 · see citing works

Light, endocrine systems, and cancer--a view from circadian biologists.

Roenneberg, T., & Lucas, R. J. (2002) · PubMed · Cited by 12 · see citing works

Circadian Dysregulation in Mental and Physical Health

Abbott, S. M., Malkani, R. G., & Zee, P. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-24288-2.00039-8 · Cited by 9 · see citing works

CIRCADIAN RHYTHMS AND THEIR APPLICATION TO OCCUPATIONAL HEALTH AND MEDICINE

Minors, D. S., & Waterhouse, J. M. (1987) · Reviews on Environmental Health · doi:10.1515/reveh.1987.7.1-2.1 · Cited by 4 · see citing works

Circadian Clocks: Implication for Health and Disease

Zee, P. C. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.09.002 · Cited by 3 · see citing works

Meal timing regulates the human circadian system

Wehrens, S. M. T., Christou, S., Isherwood, C., Middleton, B., Gibbs, M. A., Archer, S. N., Skene, D. J., & Johnston, J. D. (2017) · Current Biology · doi:10.1016/j.cub.2017.04.059 · Cited by 596 · see citing works

Hallmarks of Health

López-Otín, C., & Kroemer, G. (2021) · Cell · doi:10.1016/j.cell.2020.11.034 · Cited by 499 · see citing works

Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption

Lunn, R. M., Blask, D. E., Coogan, A. N., Figueiro, M. G., Gorman, M. R., Hall, J. E., Hansen, J., Nelson, R. J., Panda, S., Smolensky, M. H., et al. (2017) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.07.056 · Cited by 402 · see citing works

Associations between chronotype, morbidity and mortality in the UK Biobank cohort

Knutson, K. L., & von Schantz, M. (2018) · Chronobiology International · doi:10.1080/07420528.2018.1454458 · Cited by 275 · see citing works

Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism

Meléndez-Fernández, O. H., Liu, J. A., & Nelson, R. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043392 · Cited by 227 · see citing works

The chronotherapeutic treatment of bipolar disorders: A systematic review and practice recommendations from the ISBD task force on chronotherapy and chronobiology

Gottlieb, J. F., Benedetti, F., Geoffroy, P. A., Henriksen, T. E. G., Lam, R. W., Murray, G., Phelps, J., Sit, D., Swartz, H. A., Crowe, M., et al. (2019) · Bipolar Disorders · doi:10.1111/bdi.12847 · Cited by 196 · see citing works

Magnetic field effects in biology from the perspective of the radical pair mechanism

Zadeh-Haghighi, H., & Simon, C. (2022) · Journal of The Royal Society Interface · doi:10.1098/rsif.2022.0325 · Cited by 197 · see citing works

The effects of self-selected light-dark cycles and social constraints on human sleep and circadian timing: a modeling approach

Skeldon, A. C., Phillips, A. J. K., & Dijk, D.-J. (2017) · Scientific Reports · doi:10.1038/srep45158 · Cited by 155 · see citing works

Understanding the variation in exercise responses to guide personalized physical activity prescriptions

Noone, J., Mucinski, J. M., DeLany, J. P., Sparks, L. M., & Goodpaster, B. H. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2023.12.025 · Cited by 128 · see citing works

Time-of-day dependent effects of contractile activity on the phase of the skeletal muscle clock

Kemler, D., Wolff, C. A., & Esser, K. A. (2020) · The Journal of Physiology · doi:10.1113/jp279779 · Cited by 87 · see citing works

Defining circadian disruption in neurodegenerative disorders

Colwell, C. S. (2021) · Journal of Clinical Investigation · doi:10.1172/jci148288 · Cited by 90 · see citing works

Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice

Smarr, B. L., Grant, A. D., Perez, L., Zucker, I., & Kriegsfeld, L. J. (2017) · Scientific Reports · doi:10.1038/s41598-017-03406-4 · Cited by 86 · see citing works

Women temporarily synchronize their menstrual cycles with the luminance and gravimetric cycles of the Moon

Helfrich-Förster, C., Monecke, S., Spiousas, I., Hovestadt, T., Mitesser, O., & Wehr, T. A. (2021) · Science Advances · doi:10.1126/sciadv.abe1358 · Cited by 67 · see citing works

Central and peripheral circadian clocks and their role in Alzheimer's disease

Chauhan, R., Chen, K.-F., Kent, B. A., & Crowther, D. C. (2017) · Disease Models & Mechanisms · doi:10.1242/dmm.030627 · Cited by 58 · see citing works

Using Mendelian Randomisation methods to understand whether diurnal preference is causally related to mental health

O’Loughlin, J., Casanova, F., Jones, S. E., Hagenaars, S. P., Beaumont, R. N., Freathy, R. M., Watkins, E. R., Vetter, C., Rutter, M. K., Cain, S. W., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01157-3 · Cited by 44 · see citing works

Central Circadian Clock Regulates Energy Metabolism

Ding, G., Gong, Y., Eckel-Mahan, K. L., & Sun, Z. (2018) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-1286-1_5 · Cited by 33 · see citing works

Association between polarity of first episode and solar insolation in bipolar I disorder

Bauer, M., Glenn, T., Achtyes, E. D., Alda, M., Agaoglu, E., Altınbaş, K., Andreassen, O. A., Angelopoulos, E., Ardau, R., Aydin, M., et al. (2022) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2022.110982 · Cited by 14 · see citing works

Limited evidence for affective and diurnal rhythm responses to dim light-at-night in male and female C57Bl/6 mice

Cleary-Gaffney, M., & Coogan, A. N. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.03.010 · Cited by 12 · see citing works

Circadian Rhythms

Lear, B. C., & Allada, R. (2012) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0000040.pub2 · Cited by 1 · see citing works

Plant Circadian Rhythms: An Overview

Tripathi, M. (2016) · International Journal of Photochemistry

Circadian rhythms and physical activity

Racinais, S. (2008) · Cited by 2 · see citing works

Keeping time in the dark: Potato diel and circadian rhythmic gene expression reveals tissue‐specific circadian clocks

Hoopes, G. M., Zarka, D. G., Feke, A., Acheson, K., Hamilton, J. P., Douches, D. S., Buell, C. R., & Farré, E. M. (2022) · Plant Direct · doi:10.1002/pld3.425 · Cited by 19 · see citing works

Pharmacological and Genetic Approaches for the Study of Circadian Rhythms in Mammals

Turek, F. W., Pinto, L. H., Vitaterna, M. H., et al. (1995) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1995.1007 · Cited by 26 · see citing works