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Adipocytokines: leptin—the classical, resistin—the controversical, adiponectin—the promising, and more to come
Abstract
With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has been extended to the secretory products of adipocytes, since they are increasingly shown to affect several aspects in the pathogenesis of obesity-related diseases. The cloning of the ob gene is consistent with this concept and suggests that body fat content in adult rodents is regulated by a negative feedback loop centred in the hypothalamus. In recent years, a number of additional signalling molecules secreted by adipose tissue have been discovered, commonly referred to as 'adipocytokines'. Among these, adiponectin is perhaps the most interesting and promising compound for the clinician since it has profound protective actions in the pathogenesis of diabetes and cardiovascular disease. Adiponectin is low in obese subjects and, in particular, insulin-resistant patients. In contrast, resistin seems to be of greater relevance in relation to the immune stress response than in the regulation of glucose homeostasis. However, inflammatory processes have recently been connected with the development of atherosclerosis. Finally, little is known regarding the clinical relevance of visfatin. Recent research has revealed many functions of adipocytokines extending far beyond metabolism, such as immunity, cancer and bone formation. This report aims to review some of the recent topics of adipocytokine research that may be of particular importance.
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“Inflammatory molecules are likely candidates exerting a molecular link between the adipose tissue and the metabolic, cardiovascular, hepatic and thrombotic complications, and certain cancer types occurring in conjunction with or as a consequence of human obesity.”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [98]
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3 retracted
Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin
Fukuhara, A., Matsuda, M., Nishizawa, M., Segawa, K., Tanaka, M., Kishimoto, K., Matsuki, Y., Murakami, M., Ichisaka, T., Murakami, H., et al. (2005) · Science · doi:10.1126/science.1097243 · Cited by 1,906
RetractedKomazawa, N., Matsuda, M. E., Kondoh, G., Mizunoya, W., Iwaki, M., Takagi, T., Sumikawa, Y., Inoue, K., Suzuki, A., Mak, T. W., et al. (2005) · Nature Medicine · doi:10.1038/nm0605-691a · Cited by 38
RetractedKomazawa, N., Matsuda, M., Kondoh, G., Mizunoya, W., Iwaki, M., Takagi, T., Sumikawa, Y., Inoue, K., Suzuki, A., Mak, T. W., et al. (2004) · Nature Medicine · doi:10.1038/nm1117 · Cited by 36
RetractedPositional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. Adults
Calle, E. E., Rodriguez, C., Walker-Thurmond, K., & Thun, M. J. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa021423 · Cited by 7,696
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., McKee, L. J., Bauer, T. L., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602013340503 · Cited by 6,326
Adipose Tissue as an Endocrine Organ
Kershaw, E. E., & Flier, J. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0395 · Cited by 5,522
The hormone resistin links obesity to diabetes
Steppan, C. M., Bailey, S. T., Bhat, S., Brown, E. J., Banerjee, R. R., Wright, C. M., Patel, H. R., Ahima, R. S., & Lazar, M. A. (2001) · Nature · doi:10.1038/35053000 · Cited by 4,755
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes
Scherer, P. E., Williams, S. P., Fogliano, M., Baldini, G., & Lodish, H. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26746 · Cited by 3,238
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M., et al. (2003) · Nature · doi:10.1038/nature01705 · Cited by 3,176
Adiponectin and Adiponectin Receptors
Kadowaki, T., & Yamauchi, T. (2005) · Endocrine Reviews · doi:10.1210/er.2005-0005 · Cited by 2,634
Adipose tissue, adipokines, and inflammation
Fantuzzi, G. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.02.023 · Cited by 2,606
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
Berg, A. H., Combs, T. P., Du, X., Brownlee, M., & Scherer, P. E. (2001) · Nature Medicine · doi:10.1038/90992 · Cited by 2,526
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
Clément, K., Vaisse, C., Lahlou, N., Cabrol, S., Pelloux, V., Cassuto, D., Gourmelen, M., Dina, C., Chambaz, J., Lacorte, J.-M., et al. (1998) · Nature · doi:10.1038/32911 · Cited by 2,346
Abnormal splicing of the leptin receptor in diabetic mice
Lee, G.-H., Proenca, R., Montez, J. M., Carroll, K. M., Darvishzadeh, J. G., Lee, J. I., & Friedman, J. M. (1996) · Nature · doi:10.1038/379632a0 · Cited by 2,327
AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity
Hu, E., Liang, P., & Spiegelman, B. M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.18.10697 · Cited by 2,261
Elchebly, M., Payette, P., Michaliszyn, E., Cromlish, W., Collins, S., Loy, A. L., Normandin, D., Cheng, A., Himms-Hagen, J., Chan, C.-C., et al. (1999) · Science · doi:10.1126/science.283.5407.1544 · Cited by 2,210
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
Maeda, N., Shimomura, I., Kishida, K., Nishizawa, H., Matsuda, M., Nagaretani, H., Furuyama, N., Kondo, H., Takahashi, M., Arita, Y., et al. (2002) · Nature Medicine · doi:10.1038/nm724 · Cited by 2,114
Adipose Tissue, Inflammation, and Cardiovascular Disease
Berg, A. H., & Scherer, P. E. (2005) · Circulation Research · doi:10.1161/01.res.0000163635.62927.34 · Cited by 2,113
Maeda, K., Okubo, K., Shimomura, I., Funahashi, T., Matsuzawa, Y., & Matsubara, K. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0587 · Cited by 2,081
Leptin Inhibits Bone Formation through a Hypothalamic Relay
Ducy, P., Amling, M., Takeda, S., Priemel, M., Schilling, A. F., Beil, F. T., Shen, J., Vinson, C., Rueger, J. M., & Karsenty, G. (2000) · Cell · doi:10.1016/s0092-8674(00)81558-5 · Cited by 2,077
Fruebis, J., Tsao, T., Javorschi, S., Ebbets-Reed, D., Erickson, M., Yen, F. T., Bihain, B. E., & Lodish, H. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.2005 · Cited by 2,007
Leptin Regulates Bone Formation via the Sympathetic Nervous System
Takeda, S., Elefteriou, F., Levasseur, R., Liu, X., Zhao, L., Parker, K. L., Armstrong, D., Ducy, P., & Karsenty, G. (2002) · Cell · doi:10.1016/s0092-8674(02)01049-8 · Cited by 1,735
Heymsfield, S. B., Greenberg, A. S., Fujioka, K., Dixon, R. M., Kushner, R., Hunt, T., Lubina, J. A., Patane, J., Self, B., Hunt, P., et al. (1999) · JAMA · doi:10.1001/jama.282.16.1568 · Cited by 1,422
Farooqi, I. S., Matarese, G., Lord, G. M., Keogh, J. M., Lawrence, E., Agwu, C., Sanna, V., Jebb, S. A., Perna, F., Fontana, S., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15693 · Cited by 1,374
Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation
Kubota, N., Terauchi, Y., Yamauchi, T., Kubota, T., Moroi, M., Matsui, J., Eto, K., Yamashita, T., Kamon, J., Satoh, H., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c200251200 · Cited by 1,213
Adiponectin and Metabolic Syndrome
Matsuzawa, Y., Funahashi, T., Kihara, S., & Shimomura, I. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000099786.99623.ef · Cited by 1,203
Disruption of adiponectin causes insulin resistance and neointimal formation
Froguel, P. (2002) · HAL · Cited by 1,126
Adiponectin and protection against type 2 diabetes mellitus
Spranger, J., Kroke, A., Möhlig, M., Bergmann, M. M., Ristow, M., Boeing, H., & Pfeiffer, A. F. H. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12255-6 · Cited by 1,120
Structure-Function Studies of the Adipocyte-secreted Hormone Acrp30/Adiponectin
Pajvani, U. B., Du, X., Combs, T. P., Berg, A. H., Rajala, M. W., Schulthess, T., Engel, J., Brownlee, M., & Scherer, P. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m207198200 · Cited by 1,090
Resistin, an Adipokine with Potent Proinflammatory Properties
Bokarewa, M. I., Nagaev, I., Dahlberg, L., Smith, U., & Tarkowski, A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.9.5789 · Cited by 1,054
Leptin: a review of its peripheral actions and interactions
Margetic, S., Gazzola, C., Pegg, G. G., & Hill, R. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0802142 · Cited by 1,022
Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance
Bjørbæk, C., Elmquist, J. K., Frantz, J. D., Shoelson, S. E., & Flier, J. S. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80062-3 · Cited by 1,014
Resistin is expressed in human macrophages and directly regulated by PPARγ activators
Patel, L., Buckels, A. C., Kinghorn, I. J., Murdock, P. R., Holbrook, J. D., Plumpton, C., Macphee, C. H., & Smith, S. A. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02841-3 · Cited by 920
Resistin Is an Inflammatory Marker of Atherosclerosis in Humans
Reilly, M. P., Lehrke, M., Wolfe, M. L., Rohatgi, A. K., Lazar, M. A., & Rader, D. J. (2005) · Circulation · doi:10.1161/01.cir.0000155620.10387.43 · Cited by 915
Isolation and Characterization of GBP28, a Novel Gelatin-Binding Protein Purified from Human Plasma
Nakano, Y., Tobe, T., Choi-Miura, N.-H., Mazda, T., & Tomita, M. (1996) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a021483 · Cited by 915
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
Yamauchi, T., Kamon, J., Waki, H., Imai, Y., Shimozawa, N., Hioki, K., Uchida, S., Ito, Y., Takakuwa, K., Matsui, J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209033200 · Cited by 911
Apelin, a Newly Identified Adipokine Up-Regulated by Insulin and Obesity
Boucher, J., Masri, B., Daviaud, D., Gesta, S., Guigné, C., Mazzucotelli, A., Castan-Laurell, I., Tack, I., Knibiehler, B., Carpéné, C., et al. (2005) · Endocrinology · doi:10.1210/en.2004-1427 · Cited by 910
Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor
Bjørbæk, C., Uotani, S., da Silva, B., & Flier, J. S. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.51.32686 · Cited by 890
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
El-Haschimi, K., Pierroz, D. D., Hileman, S. M., Bjørbæk, C., & Flier, J. S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci9842 · Cited by 887
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
Hug, C., Wang, J., Ahmad, N. S., Bogan, J. S., Tsao, T., & Lodish, H. F. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403382101 · Cited by 873
PTP1B Regulates Leptin Signal Transduction In Vivo
Zabolotny, J. M., Bence, K. K., Stricker‐Krongrad, A., Haj, F. G., Wang, Y., Minokoshi, Y., Kim, Y., Elmquist, J. K., Tartaglia, L. A., Kahn, B. B., et al. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00148-x · Cited by 818
Defective STAT signaling by the leptin receptor in diabetic mice.
Ghilardi, N., Ziegler, S., Wiestner, A., Stoffel, R., Heim, M. H., & Skoda, R. C. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.13.6231 · Cited by 795
Adiponectin – journey from an adipocyte secretory protein to biomarker of the metabolic syndrome
TRUJILLO, M. E., & Scherer, P. E. (2005) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01426.x · Cited by 782
Iwaki, M., Matsuda, M., Maeda, N., Funahashi, T., Matsuzawa, Y., Makishima, M., & Shimomura, I. (2003) · Diabetes · doi:10.2337/diabetes.52.7.1655 · Cited by 747
Regulation of Fasted Blood Glucose by Resistin
Banerjee, R. R., Rangwala, S. M., Shapiro, J. S., Rich, A. S., Rhoades, B., Qi, Y., Wang, J., Rajala, M. W., Pocai, A., Scherer, P. E., et al. (2004) · Science · doi:10.1126/science.1092341 · Cited by 741
Bråkenhielm, E., Veitonmäki, N., Cao, R., Kihara, S., Matsuzawa, Y., Zhivotovsky, B., Funahashi, T., & Cao, Y. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308671100 · Cited by 736
Resistin Promotes Endothelial Cell Activation
Verma, S., Li, S., Wang, C., Fedak, P. W. M., Li, R., Weisel, R. D., & Mickle, D. A. G. (2003) · Circulation · doi:10.1161/01.cir.0000084503.91330.49 · Cited by 670
Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation
Fu, Y., Luo, N., Klein, R. L., & Garvey, W. T. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400373-jlr200 · Cited by 666
Holcomb, I. N., Kabakoff, R. C., Chan, B., Baker, T. W., Gurney, A. L., Henzel, W. J., Nelson, C., Lowman, H. B., Wright, B. D., Skelton, N. J., et al. (2000) · The EMBO Journal · doi:10.1093/emboj/19.15.4046 · Cited by 662
Adiponectin: action, regulation and association to insulin sensitivity
Lihn, A. S., Pedersen, S. B., & Richelsen, B. (2005) · Obesity Reviews · doi:10.1111/j.1467-789x.2005.00159.x · Cited by 660
Adiponectin: A Novel Adipokine Linking Adipocytes and Vascular Function
Goldstein, B. J., & Scalia, R. G. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0518 · Cited by 647
The role of SOCS-3 in leptin signaling and leptin resistance
Bjørbæk, C., El-Haschimi, K., Frantz, J. D., & Flier, J. S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.30059 · Cited by 639
A family of tissue-specific resistin-like molecules
Steppan, C. M., Brown, E. J., Wright, C. M., Bhat, S., Banerjee, R. R., Dai, C. Y., Enders, G. H., Silberg, D. G., Wen, X., Wu, G. D., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.502 · Cited by 635
A Cysteine-rich Adipose Tissue-specific Secretory Factor Inhibits Adipocyte Differentiation
Kim, K., Lee, K., Moon, Y. S., & Sul, H. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100028200 · Cited by 582
Leptin Signaling in the Central Nervous System and the Periphery
Bjørbæk, C. (2004) · Recent Progress in Hormone Research · doi:10.1210/rp.59.1.305 · Cited by 559
Regulation of adipocytokines and insulin resistance
Faßhauer, M., & Paschke, R. (2003) · Diabetologia · doi:10.1007/s00125-003-1228-z · Cited by 552
Molecular and anatomical determinants of central leptin resistance
Münzberg, H., & Myers, M. G. (2005) · Nature Neuroscience · doi:10.1038/nn1454 · Cited by 550
Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402367200 · Cited by 550
Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity.
Frederich, R. C., Löllmann, B., Hamann, A., Napolitano-Rosen, A., Kahn, B. B., Lowell, B. B., & Flier, J. S. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118206 · Cited by 549
Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B
Cheng, A., Uetani, N., Simoncic, P. D., Chaubey, V. P., Lee-Loy, A., McGlade, C. J., Kennedy, B. P., & Tremblay, M. L. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00149-1 · Cited by 545
Sinha, M. K., Opentanova, I., Ohannesian, J. P., Kolaczynski, J. W., Heiman, M. L., Hale, J. E., Becker, G. W., Bowsher, R. R., Stephens, T. W., & Caro, J. F. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118913 · Cited by 539
Rajala, M. W., Obici, S., Scherer, P. E., & Rossetti, L. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16521 · Cited by 527
Obesity, adipocytokines, and insulin resistance in breast cancer
Rose, D. P., Komninou, D., & Stephenson, G. D. (2004) · Obesity Reviews · doi:10.1111/j.1467-789x.2004.00142.x · Cited by 460
Böttner, A., Kratzsch, J., Müller, G., Kapellen, T. M., Blüher, S., Keller, E., Blüher, M., & Kieß, W. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0303 · Cited by 454
Self-citationAssociation of serum adiponectin levels with breast cancer risk.
Miyoshi, Y., Funahashi, T., Kihara, S., Taguchi, T., Tamaki, Y., Matsuzawa, Y., & Noguchi, S. (2003) · PubMed · Cited by 453
Xu, A., Chan, K. W., Hoo, R. L. C., Wang, Y., Tan, K. C. B., Zhang, J., Chen, B., Lam, M. C., Tse, C. A., Cooper, G. J. S., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m414231200 · Cited by 424
Way, J. M., Görgün, C. Z., Tong, Q., Uysal, K. T., Brown, K. K., Harrington, W. W., Oliver, W. R., Willson, T. M., Kliewer, S. A., & Hotamışlıgil, G. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100189200 · Cited by 414
Shetty, G. K., Economides, P. A., Horton, E. S., Mantzoros, C. S., & Veves, A. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2450 · Cited by 412
Wang, Y., Lam, K. S. L., Xu, J. Y., Lü, G., Xu, L. Y., Cooper, G. J. S., & Xu, A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501149200 · Cited by 386
Mota, N. D., Goazigo, A. R.-L., Messari, S. E., Chartrel, N., Roesch, D. M., Dujardin, C., Kordon, C., Vaudry, H., Moos, F., & Llorens‐Cortés, C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403518101 · Cited by 377
The current biology of resistin
Steppan, C. M., & Lazar, M. A. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01306.x · Cited by 371
Association of the T-G Polymorphism in Adiponectin (Exon 2) With Obesity and Insulin Sensitivity
Stumvoll, M., Tschritter, O., Fritsche, A., Staiger, H., Renn, W., Weisser, M., Machicao, F., & Häring, H. (2002) · Diabetes · doi:10.2337/diabetes.51.1.37 · Cited by 371
Influence of Leptin on Arterial Distensibility
Singhal, A., Farooqi, I. S., Cole, T. J., O’Rahilly, S., Fewtrell, M. S., Kattenhorn, M., Lucas, A., & Deanfield, J. E. (2002) · Circulation · doi:10.1161/01.cir.0000033219.24717.52 · Cited by 363
S3-12, Adipophilin, and TIP47 Package Lipid in Adipocytes
Wolins, N. E., Quaynor, B. K., Skinner, J. R., Schoenfish, M. J., Tzekov, A., & Bickel, P. E. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500978200 · Cited by 353
Adiponectin, the missing link in insulin resistance and obesity
GILCAMPOS, M. (2004) · Clinical Nutrition · doi:10.1016/j.clnu.2004.04.010 · Cited by 353
Tsao, T., Murrey, H. E., Hug, C., Lee, D. H., & Lodish, H. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c200312200 · Cited by 352
Regulation of Resistin Expression and Circulating Levels in Obesity, Diabetes, and Fasting
Rajala, M. W., Qi, Y., Patel, H. R., Takahashi, N., Banerjee, R. R., Pajvani, U. B., Sinha, M. K., Gingerich, R. L., Scherer, P. E., & Ahima, R. S. (2004) · Diabetes · doi:10.2337/diabetes.53.7.1671 · Cited by 351
Increased Resistin Gene and Protein Expression in Human Abdominal Adipose Tissue
McTernan, P. G., McTernan, C. L., Chetty, R., Jenner, K., Fisher, F. M., Lauer, M. N., Crocker, J., Barnett, A. H., & Kumar, S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.5.8627 · Cited by 350
Ashley, E. A., Powers, J. C., Chen, M. M., Kundu, R. K., Finsterbach, T., Caffarelli, A. D., Deng, A. C., EICHHORN, J., MAHAJAN, R., & Agrawal, R. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.08.018 · Cited by 345
Use of β-Blockers and Risk of Fractures
Schlienger, R. G. (2004) · JAMA · doi:10.1001/jama.292.11.1326 · Cited by 342
Calabrò, P., Samudio, I. J., Willerson, J. T., & Yeh, E. T. H. (2004) · Circulation · doi:10.1161/01.cir.0000147825.97879.e7 · Cited by 330
Gender differences in plasma leptin concentrations
Havel, P. J., Kasim-karakas, S., Dubuc, G. R., Muller, W., & Phinney, S. D. (1996) · Nature Medicine · doi:10.1038/nm0996-949b · Cited by 304
Soluble Leptin Receptor Represents the Main Leptin Binding Activity in Human Blood
Lammert, A., Kiess, W., Böttner, A., Glasow, A., & Kratzsch, J. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4885 · Cited by 297
Self-citationLow Plasma Adiponectin Levels Predict Progression of Coronary Artery Calcification
Maahs, D. M., Ogden, L. G., Kinney, G. L., Wadwa, P., Snell‐Bergeon, J. K., Dabelea, D., Hokanson, J. E., Ehrlich, J., Eckel, R. H., & Rewers, M. (2005) · Circulation · doi:10.1161/01.cir.0000155251.03724.a5 · Cited by 294
Activation of SOCS-3 by Resistin
Steppan, C. M., Wang, J., Whiteman, E. L., Birnbaum, M. J., & Lazar, M. A. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.4.1569-1575.2005 · Cited by 294
Apelin is a novel angiogenic factor in retinal endothelial cells
Kasai, A., Shintani, N., Oda, M., Kakuda, M., Hashimoto, H., Matsuda, T., Hinuma, S., & Baba, A. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.10.042 · Cited by 293
The Central Role of Perilipin A in Lipid Metabolism and Adipocyte Lipolysis
Tansey, J. T., Sztalryd, C., Hlavin, E. M., Kimmel, A. R., & Londos, C. (2004) · IUBMB Life · doi:10.1080/15216540400009968 · Cited by 275
Adenovirus-mediated chronic “hyper-resistinemia” leads to in vivo insulin resistance in normal rats
Satoh, H., Nguyen, M. T., Miles, P. D. G., Imamura, T., Usui, I., & Olefsky, J. M. (2004) · Journal of Clinical Investigation · doi:10.1172/jci20785 · Cited by 271
Modulation of Circulating Leptin Levels by Its Soluble Receptor
Huang, L., Wang, Z., & Cai, L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009795200 · Cited by 269
Fisher, F., Trujillo, M. E., Hanif, W., Barnett, A. H., McTernan, P. G., Scherer, P. E., & Kumar, S. (2005) · Diabetologia · doi:10.1007/s00125-005-1758-7 · Cited by 264
Civitarese, A. E., Jenkinson, C. P., Richardson, D. K., Bajaj, M., Cusi, K. J., Kashyap, S. R., Berria, R., Belfort, R., DeFronzo, R. A., Mandarino, L. J., et al. (2004) · Diabetologia · doi:10.1007/s00125-004-1359-x · Cited by 263
Resistin, Obesity, and Insulin Resistance — The Emerging Role of the Adipocyte as an Endocrine Organ
Shuldiner, A. R., Yang, R., & Gong, D. (2001) · New England Journal of Medicine · doi:10.1056/nejm200111013451814 · Cited by 263
Pasco, J. A., Henry, M. J., Sanders, K. M., Kotowicz, M. A., Seeman, E., & Nicholson, G. C. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.0301214 · Cited by 260
Plasma Adiponectin and Gastric Cancer
Ishikawa, M., Kitayama, J., Kazama, S., Hiramatsu, T., Hatano, K., & Nagawa, H. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.466.11.2 · Cited by 253
Baulande, S., Lasnier, F., Lucas, M., & Pairault, J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105193200 · Cited by 252
Resistin release by human adipose tissue explants in primary culture
Fain, J. N., Cheema, P. S., Bahouth, S. W., & Hiler, M. L. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02864-4 · Cited by 252
Gavrilova, O., Barr, V. A., Marcus‐Samuels, B., & Reitman, M. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.48.30546 · Cited by 244
Plasma leptin and prognosis in patients with established coronary atherosclerosis
Wolk, R. A., Berger, P. B., Lennon, R. J., Brilakis, E. S., Johnson, B. D., & Somers, V. K. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.07.050 · Cited by 235
Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease
Matsuzawa, Y. (2005) · Atherosclerosis Supplements · doi:10.1016/j.atherosclerosissup.2005.02.003 · Cited by 233
Mandard, S., Zandbergen, F., Tan, N. S., Escher, P., Patsouris, D., Koenig, W., Kleemann, R., Bakker, A., Veenman, F., Wahli, W., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403058200 · Cited by 231
Leptin and the regulation of body weight
Considine, R. V., & Caro, J. F. (1997) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(97)00050-2 · Cited by 228
Osawa, H., Yamada, K., Onuma, H., Murakami, A., Ochi, M., Kawata, H., Nishimiya, T., Niiya, T., Shimizu, I., Nishida, W., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/424761 · Cited by 228
Plasma Leptin Levels Are Associated with Coronary Atherosclerosis in Type 2 Diabetes
Reilly, M. P., Iqbal, N., Schutta, M. H., Wolfe, M. L., Scally, M., Localio, A. R., Rader, D. J., & Kimmel, S. E. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031676 · Cited by 216
Dalen, K. T., Schoonjans, K., Ulven, S. M., Weedon-Fekjær, M. S., Bentzen, T. G., Koutníková, H., Auwerx, J. H., & Nebb, H. I. (2004) · Diabetes · doi:10.2337/diabetes.53.5.1243 · Cited by 212
Yamamoto, Y., Hirose, H., Saito, I., Nishikai, K., & Saruta, T. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031163 · Cited by 210
Gerber, M., Böttner, A., Seidel, B. M., Lammert, A., Bär, J., Schuster, E., Thiery, J., Kiess, W., & Kratzsch, J. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0437 · Cited by 208
Self-citationDegawa‐Yamauchi, M., Moss, K. A., Bovenkerk, J. E., Shankar, S. S., Morrison, C. L., Lelliott, C. J., Vidal‐Puig, A., Jones, R., & Considine, R. V. (2005) · Obesity Research · doi:10.1038/oby.2005.74 · Cited by 206
Youn, B., Yu, K.-Y., Park, H. J., Lee, N. S., Min, S.-S., Youn, M. Y., Cho, Y. M., Park, Y. J., Kim, S. Y., Lee, H. K., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031121 · Cited by 206
Chen, M. B., McAinch, A. J., Macaulay, S. L., Castelli, L. A., O’Brien, P. E., Dixon, J. B., Cameron‐Smith, D., Kemp, B. E., & Steinberg, G. R. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1980 · Cited by 201
Effects of oxidative stress on adiponectin secretion and lactate production in 3T3-L1 adipocytes
Soares, A. F., Guichardant, M., Cozzone, D., Bernoud‐Hubac, N., Bouzaïdi-Tiali, N., Lagarde, M., & Géloën, A. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.12.010 · Cited by 198
Ciccone, M. M., Vettor, R., Pannacciulli, N., Minenna, A., Bellacicco, M., RIZZON, P., GIORGINO, R., & Pergola, G. D. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801623 · Cited by 195
Nilsson, L., Binart, N., Bohlooly-Y, M., Bramnert, M., Egecioglu, E., Kindblom, J., Kelly, P. A., Kopchick, J. J., Ormandy, C. J., Ling, C., et al. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.04.026 · Cited by 191
Circulating Soluble Leptin Receptor and Free Leptin Index during Childhood, Puberty, and Adolescence
Kratzsch, J., Lammert, A., Böttner, A., Seidel, B. M., Mueller, G., Thiery, J., Hebebrand, J., & Kiess, W. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020001 · Cited by 188
Self-citationGe, H., Huang, L., Pourbahrami, T., & Li, C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205825200 · Cited by 186
Peripheral metabolic actions of leptin
Muoio, D. M., & Lynis Dohm, G. (2002) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1053/beem.2002.0223 · Cited by 183
Bao, Y., Bing, C., Hunter, L., Jenkins, J. R., Wabitsch, M., & Trayhurn, P. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.11.042 · Cited by 182
Resistin Is Expressed in the Human Placenta
Yura, S., Sagawa, N., Itoh, H., Kakui, K., Nuamah, M. A., Korita, D., 竹村, 真., & Fujii, S. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-011926 · Cited by 175
Mammes, O., Betoulle, D., Aubert, R., Giraud, V., Tuzet, S., Petiet, A., Colas-Linhart, N., & Fumeron, F. (1998) · Diabetes · doi:10.2337/diabetes.47.3.487 · Cited by 170
Leptin is a growth factor in cancer
Somasundar, P. S., McFadden, D. W., Hileman, S. M., & Vona-Davis, L. C. (2004) · Journal of Surgical Research · doi:10.1016/j.jss.2003.09.004 · Cited by 167
Devos, R., Guisez, Y., der Heyden, J. V., White, D. W., Kalai, M., Fountoulakis, M., & Plaetinck, G. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.29.18304 · Cited by 166
Szopa, M., & Dembinska-Kiec, A. (2005) · Jagiellonian University Repository (Jagiellonian University) · Cited by 166
Pfützner, A., Langenfeld, M. R. W., Kunt, T., Löbig, M., & Forst, T. M. (2003) · PubMed · Cited by 162
Obesity is associated with increased levels of circulating hepatocyte growth factor
Rehman, J., Considine, R. V., Bovenkerk, J. E., Li, J., Slavens, C. A., Jones, R. M., & March, K. L. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00231-6 · Cited by 160
Fujinami, A., Obayashi, H., Ohta, K., Ichimura, T., Nishimura, M., Matsui, H., Kawahara, Y., Yamazaki, M., Ogata, M., Hasegawa, G., et al. (2003) · Clinica Chimica Acta · doi:10.1016/j.cccn.2003.09.009 · Cited by 158
Moon, B. C., Kwan, J. J., Duddy, N., Sweeney, G., & Begum, N. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00457.2002 · Cited by 154
Banks, W. A. (2004) · Peptides · doi:10.1016/j.peptides.2004.02.014 · Cited by 153
Rajala, M. W., Lin, Y., Ranalletta, M., Yang, X. M., Qian, H., Gingerich, R., Barzilai, N., & Scherer, P. E. (2002) · Molecular Endocrinology · doi:10.1210/me.2002-0048 · Cited by 153
Prostate cancer cell proliferation is influenced by leptin1
Somasundar, P. S., Frankenberry, K. A., Skinner, H. D., Vedula, G., McFadden, D. W., Riggs, D. R., Jackson, B., VanGilder, R. L., Hileman, S. M., & Vona-Davis, L. C. (2004) · Journal of Surgical Research · doi:10.1016/j.jss.2004.01.017 · Cited by 150
Subcellular Localization and Internalization of the Four Human Leptin Receptor Isoforms
Barr, V. A., Lane, K., & Taylor, S. I. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.30.21416 · Cited by 147
Generation of Human Soluble Leptin Receptor by Proteolytic Cleavage of Membrane-Anchored Receptors
Maamra, M., Bidlingmaier, M., Postel-Vinay, M. C., Wu, Z., Strasburger, C. J., & Ross, R. J. M. (2001) · Endocrinology · doi:10.1210/endo.142.10.8442 · Cited by 140
Modulation of Direct Leptin Signaling by Soluble Leptin Receptor
Yang, G., Ge, H., Boucher, A., Yu, X., & Cai, L. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0027 · Cited by 137
Hyppönen, J., Chiasson, J., Laakso, M., & the STOP-NIDDM Study Group (2005) · Diabetes · doi:10.2337/diabetes.54.3.893 · Cited by 134
Sequence variants in the 5′ flanking region of the leptin gene are associated with obesity in women
Li, W., Reed, D. R., Lee, J. H., Xu, W., Kilker, R. L., Sodam, B. R., & Price, R. A. (1999) · Annals of Human Genetics · doi:10.1046/j.1469-1809.1999.6330227.x · Cited by 132
Expression and Characterization of a Putative High Affinity Human Soluble Leptin Receptor
Liu, C., Liu, X.-J., Barry, G., LING, N. C., Maki, R. A., & Souza, E. B. D. (1997) · Endocrinology · doi:10.1210/endo.138.8.5343 · Cited by 128
Zastrow, O., Seidel, B. M., Kiess, W., Thiery, J., Keller, E., Böttner, A., & Kratzsch, J. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802432 · Cited by 125
Self-citationFilippi, E., Sentinelli, F., Romeo, S., Arca, M., Berni, A., Tiberti, C., Verrienti, A., Fanelli, M., Fallarino, M., Sorropago, G., et al. (2005) · Journal of Molecular Medicine · doi:10.1007/s00109-005-0667-z · Cited by 124
Modulation of Resistin Expression by Retinoic Acid and Vitamin A Status
Felipe, F., Bonet, M. L., Ribot, J., & Palou, A. (2004) · Diabetes · doi:10.2337/diabetes.53.4.882 · Cited by 123
Staiger, H., Kaltenbach, S., Staiger, K., Stefan, N., Fritsche, A., Guirguis, A., Péterfi, C., Weisser, M., Machicao, F. E., Stümvoll, M., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.9.2195 · Cited by 122
Frühbeck, G. (2001) · Proceedings of The Nutrition Society · doi:10.1079/pns200196 · Cited by 120
An update on the biology and physiology of resistin
Adeghate, E. A. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4083-2 · Cited by 117
The role of the adipocyte hormone adiponectin in cardiovascular disease
Hug, C., & Lodish, H. F. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2005.01.001 · Cited by 113
Kim, K., Zhao, L., Moon, Y., Kang, C., & Sul, H. S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305905101 · Cited by 111
Heptulla, R. A., Smitten, A. L., Teague, B., Tamborlane, W. V., Ma, Y.-Z., & Caprio, S. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7136 · Cited by 109
Park, S.-K., Oh, S.-Y., Lee, M., Yoon, S., Kim, K., & Kim, J. W. (2004) · Diabetes · doi:10.2337/diabetes.53.11.2757 · Cited by 109
Role of Hepatocyte Growth Factor in Breast Cancer: A Novel Mitogenic Factor Secreted by Adipocytes
Rahimi, N., Saulnier, R., Nakamura, T., Park, M., & Elliott, B. E. (1994) · DNA and Cell Biology · doi:10.1089/dna.1994.13.1189 · Cited by 107
Kang, E. S., Park, S., Kim, H. J., Ahn, C. W., Nam, M., Soo, B., Lim, S. K., Kim, K. R., & Lee, H. C. (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1139 · Cited by 107
Juan, C., Au, L., Fang, V. S., Kang, S.-F., Ko, Y., Kuo, S.-F., Hsu, Y.-P., Kwok, C., & Ho, L.-T. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.6132 · Cited by 106
Resistin is expressed in pancreatic islets
Minn, A. H., Patterson, N. B., Pack, S., Hoffmann, S. C., Gavrilova, O., Vinson, C., Harlan, D. M., & Shalev, A. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.09.061 · Cited by 102
Adipocyte-derived cytokine resistin causes endothelial dysfunction of porcine coronary arteries
Kougias, P., Chai, H., Lin, P. H., Lumsden, A. B., Yao, Q. C., & Chen, C. (2005) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2004.12.046 · Cited by 99
Adiponutrin: A New Gene Regulated by Energy Balance in Human Adipose Tissue
Liu, Y., Moldes, M., Bastard, J., Bruckert, É., Viguerie, N., Hainque, B., Basdevant, A., Langin, D., Pairault, J., & Clément, K. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031978 · Cited by 99
Adiponectin Receptor 1 Gene (ADIPOR1) as a Candidate for Type 2 Diabetes and Insulin Resistance
Wang, H., Zhang, H., Jia, Y., Zhang, Z., Craig, R. L., Wang, X., & Elbein, S. C. (2004) · Diabetes · doi:10.2337/diabetes.53.8.2132 · Cited by 99
Regulation of adiponectin receptor gene expression in diabetic mice
Inukai, K., Nakashima, Y., Watanabe, M., Takata, N., Sawa, T., Kurihara, S., Awata, T., & Katayama, S. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00118.2004 · Cited by 98
Resistin: an adipocyte‐derived hormone. Has it a role in diabetes and obesity?
Rea, R., & Donnelly, R. (2004) · Diabetes Obesity and Metabolism · doi:10.1111/j.1462-8902.2004.00334.x · Cited by 91
Conneely, K. N., Silander, K., Scott, L. J., Mohlke, K. L., Lazaridis, K. N., Valle, T. T., Tuomilehto, J., Bergman, R. N., Watanabe, R. M., Buchanan, T. A., et al. (2004) · Diabetologia · doi:10.1007/s00125-004-1537-x · Cited by 90
Vasseur, F., Leprêtre, F., Lacquemant, C., & Froguel, P. (2003) · Current Diabetes Reports · doi:10.1007/s11892-003-0039-4 · Cited by 90
Adenovirus-Mediated High Expression of Resistin Causes Dyslipidemia in Mice
Sato, N., Kobayashi, K., Inoguchi, T., Sonoda, N., Imamura, M., Sekiguchi, N., Nakashima, N., & Nawata, H. (2004) · Endocrinology · doi:10.1210/en.2004-0985 · Cited by 82
Jung, H. S., Youn, B., Cho, Y. M., Yu, K.-Y., Park, H. J., Shin, C. S., Kim, S. Y., Lee, H. K., & Park, K. S. (2005) · Metabolism · doi:10.1016/j.metabol.2004.05.019 · Cited by 81
Kita, A., Yamasaki, H., Kuwahara, H., Moriuchi, A., Fukushima, K., Kobayashi, M., Fukushima, T., Takahashi, R., Abiru, N., Uotani, S., et al. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.03.205 · Cited by 76
Resistin, but not adiponectin, inhibits dopamine and norepinephrine release in the hypothalamus
Brunetti, L., Orlando, G., Recinella, L., Michelotto, B., Ferrante, C., & Vacca, M. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.04.020 · Cited by 75
Ort, T., Arjona, A. A., MacDougall, J. R., Nelson, P. J., Rothenberg, M. E., Wu, F. S.-Y., Eisen, A., & Halvorsen, Y. C. (2005) · Endocrinology · doi:10.1210/en.2004-1421 · Cited by 74
Central control of bone remodeling
Takeda, S. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.11.071 · Cited by 69
Seo, J. B., Noh, M. J., Yoo, E. J., Park, S. Y., Park, J., Lee, I. K., Park, S. D., & Kim, J. B. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0028 · Cited by 59
Battu, A., Ghosh, S., Singh, A., Mande, S. C., Srinivas, V., Chauhan, R., & Ehtesham, N. Z. (2003) · Biochemistry · doi:10.1021/bi034782v · Cited by 57
Binding of a pure 125I-monoiodoleptin analog to mouse tissues: a developmental study
Farra, C. D., Zsürger, N., Vincent, J., & Cupo, A. (2000) · Peptides · doi:10.1016/s0196-9781(00)00182-0 · Cited by 55
Wilkinson, M., Wilkinson, D. A., Wiesner, G., Morash, B. A., & Ur, E. (2005) · Neuroendocrinology · doi:10.1159/000084871 · Cited by 52
Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy
Williamson, D. A., Ravussin, É., Wong, M., Wagner, A., DiPaoli, A., Çağlayan, S., Özata, M., Martin, C. K., Walden, H. M., Arnett, C., et al. (2005) · Appetite · doi:10.1016/j.appet.2005.01.002 · Cited by 51
Polson, D. A., & Thompson, M. P. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)03027-9 · Cited by 49
Bouchard, L., Weisnagel, S. J., Engert, J. C., Hudson, T. J., Bouchard, C., Vohl, M., & Përusse, L. (2004) · Journal of Endocrinological Investigation · doi:10.1007/bf03345301 · Cited by 45
Dehydroepiandrosterone up-regulates resistin gene expression in white adipose tissue
Kochan, Z., & Karbowska, J. (2004) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2003.12.012 · Cited by 45
Chung, S. S., Choi, H., Kim, K. W., Cho, Y., Lee, H. K., & Park, K. S. (2005) · Diabetologia · doi:10.1007/s00125-005-1762-y · Cited by 44
Nohira, T., Nagao, K., Kameyama, K., Nakai, H., Fukumine, N., Okabe, K., Kitano, S., & Hisatomi, H. (2004) · European Journal of Endocrinology · doi:10.1530/eje.0.1510151 · Cited by 41
Kitagawa, Y., Bujo, H., Takahashi, K., Shibasaki, M., Ishikawa, K., Yagui, K., Hashimoto, N., Noda, K., Nakamura, T., Yano, S., et al. (2004) · Diabetologia · doi:10.1007/s00125-004-1530-4 · Cited by 37
IGF-I downregulates resistin gene expression and protein secretion
Chen, Y.-H., Hung, P.-F., & Kao, Y.-H. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00325.2004 · Cited by 36
Wong, M., Licinio, J., Yıldız, B. O., Mantzoros, C. S., Prolo, P., Kling, M. A., & Gold, P. W. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031275 · Cited by 35
Dimerization of human recombinant resistin involves covalent and noncovalent interactions
Pullakhandam, R., Ghosh, S., Soundarya, K., Haseeb, A., Battu, A., & Ehtesham, N. Z. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.156 · Cited by 27
Lessons Learned from Gene Targeting and Transgenesis for Adrenal Physiology and Disease
Böttner, A., & Bornstein, S. R. (2001) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/a:1011568516406 · Cited by 3
Flagged first, then by citations
2 of the 179 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Böttner A, Kratzsch J, Seidel B, et al. Adiponectin expression is dependent on differentiation of adipocytes. In press.
- Hug, 2005, Medicine. Visfatin: a new adipokine. Science, 307, 366
Cited by
Sorted by citations
Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098
Obesity, inflammation and the immune system
de Heredia, F. P., Gómez-Martínez, S., & Marcos, A. (2012) · Proceedings of the Nutrition Society · doi:10.1017/s0029665112000092 · Cited by 845
Leptin and Cardiovascular Disease
Koh, K. K., Park, S. M., & Quon, M. J. (2008) · Circulation · doi:10.1161/circulationaha.107.741645 · Cited by 481
The role of resistin as a regulator of inflammation: Implications for various human pathologies
Filková, M., Haluzík, M., Gay, S., & Šenolt, L. (2009) · Clinical Immunology · doi:10.1016/j.clim.2009.07.013 · Cited by 451
Nishimura, S., Manabe, I., Nagasaki, M., Hosoya, Y., Yamashita, H., Fujita, H., Ohsugi, M., Tobe, K., Kadowaki, T., Nagai, R., et al. (2007) · Diabetes · doi:10.2337/db06-1749 · Cited by 440
Metadata
- Authors
- Koerner, A., Kratzsch, J., & Kiess, W.
- Affiliations
- Leipzig University (DE)
- University Hospital Leipzig (DE)
- Venue
- Best Practice & Research Clinical Endocrinology & Metabolism
- Publisher
- Elsevier BV
- Published
- 2005-12
- Volume
- 19
- Issue
- 4
- Pages
- 525-546
- ISSN
- 1521-690X (ISSN-L)
- OpenAlex
- W1973692442
- Cited by
- 471
- References
- 179
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 9 · 2023: 13 · 2022: 19 · 2021: 19 · 2020: 4 · 2019: 11 · 2018: 21 · 2017: 15 · 2016: 22 · 2015: 27 · 2014: 33 · 2013: 33 · 2012: 37
- FWCI
- 4.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Best Practice & Research Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Keywords
- adipokines, leptin, resistin, adiponectin, visfatin, obesity, adipose tissue, insulin resistance, diabetes mellitus, cardiovascular disease, atherosclerosis, inflammation, immune response, cancer, bone formation
- MeSH terms
- Adipose Tissue, Animals, Cardiovascular Diseases, Diabetes Mellitus, Humans, Insulin Resistance, Cytokines, Leptin, Mice, Adiponectin, Resistin, Nicotinamide Phosphoribosyltransferase
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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