Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

Heart disease and stroke statistics-2018 update: a report from the american heart association

Benjamin, E. J., Virani, S. S., Callaway, C. W., Chamberlain, A. M., Chang, A. R., Cheng, S., Chiuve, S. E., Cushman, M., Delling, F. N., Deo, R., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000558 · Cited by 7,146

Mechanical properties and the hierarchical structure of bone

Rho, J. Y., Kuhn, L. T., & Zioupos, P. (1998) · Medical Engineering & Physics · doi:10.1016/s1350-4533(98)00007-1 · Cited by 2,596

Global burden of COPD: risk factors, prevalence, and future trends

Mannino, D. M., & Buist, A. S. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61380-4 · Cited by 2,120

Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink

Pati, F., Jang, J., Ha, D.-H., Won Kim, S., Rhie, J.-W., Shim, J.-H., Kim, D.-H., & Cho, D.-W. (2014) · Nature Communications · doi:10.1038/ncomms4935 · Cited by 1,904

Polymeric Scaffolds in Tissue Engineering Application: A Review

Dhandayuthapani, B., Yoshida, Y., Maekawa, T., & Kumar, D. S. (2011) · International Journal of Polymer Science · doi:10.1155/2011/290602 · Cited by 1,773

Tough adhesives for diverse wet surfaces

Li, J., Celiz, A. D., Yang, J., Yang, Q., Wamala, I., Whyte, W., Seo, B. R., Vasilyev, N. V., Vlassak, J. J., Suo, Z., et al. (2017) · Science · doi:10.1126/science.aah6362 · Cited by 1,610

Skin immune sentinels in health and disease

Nestle, F. O., Meglio, P. D., Qin, J., & Nickoloff, B. J. (2009) · Nature reviews. Immunology · doi:10.1038/nri2622 · Cited by 1,529

Physical approaches to biomaterial design

Mitragotri, S., & Lahann, J. (2009) · Nature Materials · doi:10.1038/nmat2344 · Cited by 1,445

Extracellular matrix: A dynamic microenvironment for stem cell niche

Gattazzo, F., Urciuolo, A., & Bonaldo, P. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.01.010 · Cited by 1,365

Unlike Bone, Cartilage Regeneration Remains Elusive

Huey, D. J., Hu, J. C. Y., & Athanasiou, K. A. (2012) · Science · doi:10.1126/science.1222454 · Cited by 1,209

Advancing biomaterials of human origin for tissue engineering

Chen, F.-M., & Liu, X. (2016) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2015.02.004 · Cited by 1,158

Extracellular matrix-based materials for regenerative medicine

Hussey, G. S., Dziki, J. L., & Badylak, S. F. (2018) · Nature Reviews Materials · doi:10.1038/s41578-018-0023-x · Cited by 844

Extracellular matrix hydrogels from decellularized tissues: Structure and function

Saldin, L. T., Cramer, M. C., Velankar, S., White, L. J., & Badylak, S. F. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.11.068 · Cited by 841

Design of biodegradable, implantable devices towards clinical translation

Li, C., Guo, C., Fitzpatrick, V., Ibrahim, A. G. A., Zwierstra, M. J., Hanna, P. C., Lechtig, A., Nazarian, A., Lin, S. J., & Kaplan, D. L. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0150-z · Cited by 828

Microencapsulation of probiotics for gastrointestinal delivery

Cook, M. T., Tzortzis, G., Charalampopoulos, D., & Khutoryanskiy, V. V. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.06.003 · Cited by 791

Multifunctional chondroitin sulphate for cartilage tissue–biomaterial integration

Wang, D., Varghese, S., Sharma, B., Strehin, I. A., Fermanian, S., Gorham, J. M., Fairbrother, D. H., Cascio, B. M., & Elisseeff, J. H. (2007) · Nature Materials · doi:10.1038/nmat1890 · Cited by 695

3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair

Jang, J., Park, H.-J., Kim, S.-W., Kim, H., Park, J. Y., Na, S. J., Kim, H. J., Park, M. N., Choi, S. H., Park, S. H., et al. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2016.10.026 · Cited by 673

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

Keane, T. J., Swinehart, I. T., & Badylak, S. F. (2015) · Methods · doi:10.1016/j.ymeth.2015.03.005 · Cited by 670

Bioinspired mechanically active adhesive dressings to accelerate wound closure

Blacklow, S. O., Li, J., Freedman, B. R., Zeidi, M., Chen, C., & Mooney, D. J. (2019) · Science Advances · doi:10.1126/sciadv.aaw3963 · Cited by 555

Extracellular matrix scaffolds for cartilage and bone regeneration

Benders, K. E. M., van Weeren, P. R., Badylak, S. F., Saris, D. B. F., Dhert, W. J. A., & Malda, J. (2013) · Trends in biotechnology · doi:10.1016/j.tibtech.2012.12.004 · Cited by 539

Challenges in Cardiac Tissue Engineering

Vunjak-Novakovic, G., Tandon, N., Godier, A. F. G., Maidhof, R., Marsano, A., Martens, T., & Radišić, M. (2009) · Tissue engineering. Part B, Reviews · doi:10.1089/ten.teb.2009.0352 · Cited by 521

3D cell printing of in vitro stabilized skin model and in vivo pre-vascularized skin patch using tissue-specific extracellular matrix bioink: A step towards advanced skin tissue engineering

Kim, B. S., Kwon, Y. W., Kong, J., Park, G. T., Gao, G., Han, W., Kim, M., Lee, H., Kim, J. H., & Cho, D. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.03.040 · Cited by 518

A hydrogel derived from decellularized dermal extracellular matrix

Wolf, M. T., Daly, K. A., Brennan-Pierce, E. P., Johnson, S. A., Carruthers, C. A., D'Amore, A., Nagarkar, S. P., Velankar, S. S., & Badylak, S. F. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.06.051 · Cited by 482

Elastic modulus measurements of human liver and correlation with pathology

Yeh, W., Li, P., Jeng, Y., Hsu, H., Kuo, P.-L., Li, M., Yang, P., & Lee, P. (2002) · Ultrasound in Medicine & Biology · doi:10.1016/s0301-5629(02)00489-1 · Cited by 459

Matrix-bound nanovesicles within ECM bioscaffolds

Huleihel, L., Hussey, G. S., Naranjo, J. D., Zhang, L., Dziki, J. L., Turner, N. J., Stolz, D. B., & Badylak, S. F. (2016) · Science Advances · doi:10.1126/sciadv.1600502 · Cited by 387

Biomimetic 3D tissue printing for soft tissue regeneration

Pati, F., Ha, D.-H., Jang, J., Han, H. H., Rhie, J.-W., & Cho, D.-W. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.05.043 · Cited by 368

Overview of the Cornea

Eghrari, A. O., Riazuddin, S. A., & Gottsch, J. D. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.04.001 · Cited by 359

The Pivotal Role of Vascularization in Tissue Engineering

Auger, F. A., Gibot, L., & Lacroix, D. A. (2013) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071812-152428 · Cited by 352

Procedure, applications, and outcomes of autologous fat grafting

Simonacci, F., Bertozzi, N., Grieco, M. P., Grignaffini, E., & Raposio, E. (2017) · Annals of Medicine and Surgery · doi:10.1016/j.amsu.2017.06.059 · Cited by 344

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

Zhu, D., Li, Z., Huang, K., Caranasos, T. G., Rossi, J. S., & Cheng, K. (2021) · Nature Communications · doi:10.1038/s41467-021-21682-7 · Cited by 341

Tissue Engineered Bio‐Blood‐Vessels Constructed Using a Tissue‐Specific Bioink and 3D Coaxial Cell Printing Technique: A Novel Therapy for Ischemic Disease

Gao, G., Lee, J. H., Jang, J., Lee, D., Kong, J., Kim, B. S., Choi, Y., Jang, W. B., Hong, Y. J., Kwon, S., et al. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201700798 · Cited by 340

Development of Liver Decellularized Extracellular Matrix Bioink for Three-Dimensional Cell Printing-Based Liver Tissue Engineering

Lee, H., Han, W., Kim, H., Ha, D., Jang, J., Kim, B. S., & Cho, D. (2017) · Biomacromolecules · doi:10.1021/acs.biomac.6b01908 · Cited by 334

Fat Grafting

Gir, P., Brown, S. A., Oni, G., Kashefi, N., Mojallal, A. A., & Rohrich, R. J. (2012) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0b013e318254b4d3 · Cited by 333

In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration

Zhu, M., Li, W., Dong, X., Yuan, X., Midgley, A. C., Chang, H., Wang, Y., Wang, H., Wang, K., Ma, P. X., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12545-3 · Cited by 322

A 3D cell printed muscle construct with tissue-derived bioink for the treatment of volumetric muscle loss

Choi, Y., Jun, Y. J., Kim, D., Yi, H., Chae, S.-H., Kang, J.-S., Lee, J., Gao, G., Kong, J., Jang, J., et al. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.03.036 · Cited by 319

Development of the Mammalian Kidney

McMahon, A. P. (2016) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2015.10.010 · Cited by 317

Tissue Engineering of Articular Cartilage with Biomimetic Zones

Klein, T. J., Malda, J., Sah, R. L., & Hutmacher, D. W. (2009) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2008.0563 · Cited by 314

Mechanisms of pore formation in hydrogel scaffolds textured by freeze-drying

Grenier, J., Duval, H., Barou, F., Lv, P., David, B., & Letourneur, D. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.05.070 · Cited by 313

Versatile click alginate hydrogels crosslinked via tetrazine–norbornene chemistry

Desai, R. M., Koshy, S. T., Hilderbrand, S. A., Mooney, D. J., & Joshi, N. S. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.01.048 · Cited by 300

3D cell printing of functional skeletal muscle constructs using skeletal muscle-derived bioink

Choi, Y., Kim, T. G., Jeong, J., Yi, H., Park, J. W., Hwang, W., & Cho, D. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600483 · Cited by 298

Hydrogels derived from demineralized and decellularized bone extracellular matrix

Sawkins, M. J., Bowen, W., Dhadda, P., Markides, H., Sidney, L. E., Taylor, A. J., Rose, F. R. A. J., Badylak, S. F., Shakesheff, K. M., & White, L. J. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.04.029 · Cited by 282

Rapid 3D bioprinting of decellularized extracellular matrix with regionally varied mechanical properties and biomimetic microarchitecture

Ma, X., Yu, C., Wang, P., Xu, W., Wan, X., Lai, C. S. E., Liu, J., Koroleva-Maharajh, A., & Chen, S. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.09.026 · Cited by 281

Hydrogels derived from central nervous system extracellular matrix

Medberry, C. J., Crapo, P. M., Siu, B. F., Carruthers, C. A., Wolf, M. T., Nagarkar, S. P., Agrawal, V., Jones, K. E., Kelly, J., Johnson, S. A., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.10.062 · Cited by 278

Scanningless and continuous 3D bioprinting of human tissues with decellularized extracellular matrix

Yu, C., Ma, X., Zhu, W., Wang, P., Miller, K. L., Stupin, J., Koroleva-Maharajh, A., Hairabedian, A., & Chen, S. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2018.12.009 · Cited by 272

Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas

Sackett, S. D., Tremmel, D. M., Ma, F., Feeney, A. K., Maguire, R. M., Brown, M. E., Zhou, Y., Li, X., O’Brien, C., Li, L., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-28857-1 · Cited by 269

A Photo‐Crosslinkable Kidney ECM‐Derived Bioink Accelerates Renal Tissue Formation

Ali, M., PR, A. K., Yoo, J. J., Zahran, F., Atala, A., & Lee, S. J. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201800992 · Cited by 264

Enhancing cell infiltration of electrospun fibrous scaffolds in tissue regeneration

Wu, J., & Hong, Y. (2016) · Bioactive Materials · doi:10.1016/j.bioactmat.2016.07.001 · Cited by 262

The promotion of a constructive macrophage phenotype by solubilized extracellular matrix

Sicari, B. M., Dziki, J. L., Siu, B. F., Medberry, C. J., Dearth, C. L., & Badylak, S. F. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.06.060 · Cited by 255

A Bioprinted Cardiac Patch Composed of Cardiac‐Specific Extracellular Matrix and Progenitor Cells for Heart Repair

Bejleri, D., Streeter, B. W., Nachlas, A. L. Y., Brown, M. E., Gaetani, R., Christman, K. L., & Davis, M. E. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201800672 · Cited by 255

Extracellular‐Matrix‐Reinforced Bioinks for 3D Bioprinting Human Tissue

Santis, M. M. D., Alsafadi, H. N., Taş, S., Bölükbas, D. A., Prithiviraj, S., Silva, I. A. N., Mittendorfer, M., Ota, C., Stegmayr, J., Daoud, F., et al. (2020) · Advanced Materials · doi:10.1002/adma.202005476 · Cited by 244

Engineered Liver-On-A-Chip Platform to Mimic Liver Functions and Its Biomedical Applications: A Review

Deng, J., Wei, W., Chen, Z., Lin, B., Zhao, W., Luo, Y., & Zhang, X. (2019) · Micromachines · doi:10.3390/mi10100676 · Cited by 238

Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats

Li, R., Li, Y., Wu, Y., Zhao, Y., Chen, H. A., Yuan, Y., Xu, K., Zhang, H., Lu, Y., Wang, J., et al. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.03.044 · Cited by 236

Liver extracellular matrix providing dual functions of two-dimensional substrate coating and three-dimensional injectable hydrogel platform for liver tissue engineering

Lee, J. S., Shin, J., Park, H.-M., Kim, Y.-G., Kim, B.-G., Oh, J.-W., & Cho, S.-W. (2014) · Biomacromolecules · doi:10.1021/bm4015039 · Cited by 236

Transversely isotropic tensile material properties of skeletal muscle tissue

Morrow, D. A., Donahue, T. L. H., Odegard, G. M., & Kaufman, K. R. (2009) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2009.03.004 · Cited by 235

Architecture and function in the muscle sarcomere

Squire, J. M. (1997) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(97)80033-4 · Cited by 226

Fabrication of liver microtissue with liver decellularized extracellular matrix (dECM) bioink by digital light processing (DLP) bioprinting

Mao, Q., Wang, Y., Li, Y., Juengpanich, S., Li, W., Chen, M., Yin, J., Fu, J., & Cai, X. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.110625 · Cited by 222

Composite hydrogel scaffolds incorporating decellularized adipose tissue for soft tissue engineering with adipose-derived stem cells

Cheung, H. K., Han, T. T. Y., Marecak, D. M., Watkins, J. F., Amsden, B. G., & Flynn, L. E. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.11.067 · Cited by 212

Electrospun gelatin scaffolds incorporating rat decellularized brain extracellular matrix for neural tissue engineering

Baiguera, S., Gaudio, C. D., Lucatelli, E., Kuevda, E. V., Boieri, M., Mazzanti, B., Bianco, A., & Macchiarini, P. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.060 · Cited by 211

Emerging Technologies for Gut Microbiome Research

Arnold, J. W., Roach, J. M., & Azcárate-Peril, M. A. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.06.008 · Cited by 206

Hydrogel systems and their role in neural tissue engineering

Madhusudanan, P., Raju, G., & Shankarappa, S. A. (2020) · Journal of The Royal Society Interface · doi:10.1098/rsif.2019.0505 · Cited by 201

Vascularized and Innervated Skeletal Muscle Tissue Engineering

Gilbert‐Honick, J., & Grayson, W. L. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900626 · Cited by 197

An injectable extracellular matrix derived hydrogel for meniscus repair and regeneration

Wu, J., Ding, Q., Dutta, A., Wang, Y., Huang, Y.-H., Weng, H., Tang, L., & Hong, Y. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.01.027 · Cited by 196

3D printing electrospinning fiber-reinforced decellularized extracellular matrix for cartilage regeneration

Chen, W., Xu, Y., Li, Y., Jia, L., Mo, X., Jiang, G., & Zhou, G. (2019) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.122986 · Cited by 193

Macrophages, Wound Healing, and Fibrosis: Recent Insights

Smigiel, K. S., & Parks, W. C. (2018) · Current Rheumatology Reports · doi:10.1007/s11926-018-0725-5 · Cited by 185

Understanding the role of tissue-specific decellularized spinal cord matrix hydrogel for neural stem/progenitor cell microenvironment reconstruction and spinal cord injury

Xu, Y., Zhou, J., Liu, C., Zhang, S., Gao, F., Guo, W., Sun, X., Zhang, C., Li, H., Rao, Z., et al. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120596 · Cited by 183

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function

Skardal, A., Smith, L., Bharadwaj, S., Atala, A., Soker, S., & Zhang, Y. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.03.034 · Cited by 183

3D bioprinting of mechanically tuned bioinks derived from cardiac decellularized extracellular matrix

Shin, Y. J., Shafranek, R. T., Tsui, J. H., Walcott, J. C., Nelson, A., & Kim, D. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.11.006 · Cited by 181

The Bioactivity of Cartilage Extracellular Matrix in Articular Cartilage Regeneration

Sutherland, A. J., Converse, G. L., Hopkins, R. A., & Detamore, M. S. (2014) · Advanced Healthcare Materials · doi:10.1002/adhm.201400165 · Cited by 180

Designing Scaffolds for Corneal Regeneration

Ahearne, M., Fernández‐Pérez, J., Masterton, S., Madden, P. W., & Bhattacharjee, P. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201908996 · Cited by 177

Decellularized heart ECM hydrogel using supercritical carbon dioxide for improved angiogenesis

Seo, Y., Jung, Y., & Kim, S. H. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.11.046 · Cited by 174

Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects

Lin, T., Liu, S., Chen, S., Qiu, S., Rao, Z., Liu, J., Zhu, S., Yan, L., Mao, H., Zhu, Q., et al. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.04.001 · Cited by 166

Precise stacking of decellularized extracellular matrix based 3D cell-laden constructs by a 3D cell printing system equipped with heating modules

Ahn, G., Min, K., Kim, C., Lee, S., Kang, D., Won, J.-Y., Cho, D., Kim, J., Jin, S., Yun, W., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-09201-5 · Cited by 165

Decellularized extracellular matrix-based bio-ink with enhanced 3D printability and mechanical properties

Kim, M. K., Jeong, W., Lee, S., Kim, J. B., Jin, S., & Kang, H. (2019) · Biofabrication · doi:10.1088/1758-5090/ab5d80 · Cited by 165

Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue

de Hilster, R. H. J., Sharma, P. K., Jonker, M. R., White, E. S., Gercama, E. A., Roobeek, M., Timens, W., Harmsen, M. C., Hylkema, M. N., & Burgess, J. K. (2020) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00451.2019 · Cited by 163

Injectable Extracellular Matrix Hydrogels as Scaffolds for Spinal Cord Injury Repair

Tukmachev, D., Forostyak, S., Kočí, Z., Zaviskova, K., Vacková, I., Výborný, K., Sandvig, I., Sandvig, A., Medberry, C. J., Badylak, S. F., et al. (2016) · Tissue Engineering Part A · doi:10.1089/ten.tea.2015.0422 · Cited by 163

Long-term outcome following heart transplantation: current perspective

Wilhelm, M. J. (2015) · PubMed Central · doi:10.5167/uzh-119976 · Cited by 161

Advances in the development of biodegradable coronary stents: A translational perspective

Zong, J., He, Q., Liu, Y., Qiu, M., Wu, J., & Hu, B. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100368 · Cited by 160

Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model

DeQuach, J. A., Lin, J., Cam, C., Hu, D. P., Salvatore, M., Sheikh, F., & Christman, K. L. (2012) · European Cells and Materials · doi:10.22203/ecm.v023a31 · Cited by 159

A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering

Visscher, D. O., Lee, H., van Zuijlen, P. P. M., Helder, M. N., Atala, A., Yoo, J. J., & Lee, S. J. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.11.029 · Cited by 154

The Use of Extracellular Matrix as an Inductive Scaffold for the Partial Replacement of Functional Myocardium

Badylak, S. F., Kochupura, P. V., Cohen, I. S., Doronin, S. V., Saltman, A. E., Gilbert, T. W., Kelly, D. J., Ignotz, R. A., & Gaudette, G. R. (2006) · Cell Transplantation · doi:10.3727/000000006783982368 · Cited by 153

Quantification of Extracellular Matrix Proteins from a Rat Lung Scaffold to Provide a Molecular Readout for Tissue Engineering

Hill, R. C., Calle, E. A., Dzieciątkowska, M., Niklason, L. E., & Hansen, K. C. (2015) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m114.045260 · Cited by 153

Development and characterization of a naturally derived lung extracellular matrix hydrogel

Pouliot, R. A., Link, P. A., Mikhaiel, N. S., Schneck, M. B., Valentine, M. S., Gninzeko, F. J. K., Herbert, J. A., Sakagami, M., & Heise, R. L. (2016) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35726 · Cited by 153

Concentration-dependent rheological properties of ECM hydrogel for intracerebral delivery to a stroke cavity

Massensini, A. R., Ghuman, H., Saldin, L. T., Medberry, C. J., Keane, T. J., Nicholls, F. J., Velankar, S., Badylak, S. F., & Modo, M. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.08.040 · Cited by 152

Polypropylene surgical mesh coated with extracellular matrix mitigates the host foreign body response

Wolf, M. T., Carruthers, C. A., Dearth, C. L., Crapo, P. M., Huber, A., Burnsed, O. A., Londoño, R., Johnson, S. A., Daly, K. A., Stahl, E. C., et al. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34671 · Cited by 152

Crosslinker-free silk/decellularized extracellular matrix porous bioink for 3D bioprinting-based cartilage tissue engineering

Zhang, X., Liu, Y., Luo, C., Zhai, C., Li, Z., Zhang, Y., Yuan, T., Dong, S., Zhang, J., & Fan, W. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111388 · Cited by 152

Decellularized Cartilage May Be a Chondroinductive Material for Osteochondral Tissue Engineering

Sutherland, A. J., Beck, E. C., Dennis, S. C., Converse, G. L., Hopkins, R. A., Berkland, C. J., & Detamore, M. S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121966 · Cited by 151

Decellularized extracellular matrix bioinks and the external stimuli to enhance cardiac tissue development in vitro

Das, S., Kim, S.-W., Choi, Y.-J., Lee, S., Lee, S.-H., Kong, J.-S., Park, H.-J., Cho, D.-W., & Jang, J. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.04.026 · Cited by 150

Injectable thermosensitive PEG–PCL–PEG hydrogel/acellular bone matrix composite for bone regeneration in cranial defects

Ni, P., Ding, Q., Fan, M., Liao, J., Qian, Z., Luo, J., Li, X., Luo, F., Yang, Z., & Wei, Y. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.016 · Cited by 150

Three-dimensional liver-derived extracellular matrix hydrogel promotes liver organoids function

Saheli, M., Sepantafar, M., Pournasr, B., Farzaneh, Z., Vosough, M., Piryaei, A., & Baharvand, H. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26622 · Cited by 148

3D cell-printing of biocompatible and functional meniscus constructs using meniscus‐derived bioink

Chae, S., Lee, S., Choi, Y., Hong, D. H., Gao, G., Wang, J. H., & Cho, D. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120466 · Cited by 148

A Biodegradable, Acellular Xenogeneic Scaffold for Regeneration of the Vocal Fold Lamina Propria

Xu, C. C., Chan, R. W., & Tirunagari, N. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0169 · Cited by 148

Light‐Activated Decellularized Extracellular Matrix‐Based Bioinks for Volumetric Tissue Analogs at the Centimeter Scale

Kim, H., Kang, B., Cui, X., Lee, S., Lee, K., Cho, D., Hwang, W., Woodfield, T. B. F., Lim, K. S., & Jang, J. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202011252 · Cited by 144

ECM hydrogel for the treatment of stroke: Characterization of the host cell infiltrate

Ghuman, H., Massensini, A. R., Donnelly, J., Kim, S., Medberry, C. J., Badylak, S. F., & Modo, M. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.03.014 · Cited by 142

Generation of a 3D Liver Model Comprising Human Extracellular Matrix in an Alginate/Gelatin-Based Bioink by Extrusion Bioprinting for Infection and Transduction Studies

Hiller, T., Berg, J., Elomaa, L., Röhrs, V., Ullah, I., Schaar, K., Dietrich, A.-C., Al‐Zeer, M. A., Kurtz, A., Hocke, A. C., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103129 · Cited by 141

Characterization of cornea-specific bioink: high transparency, improved in vivo safety

Kim, H., Park, M. N., Kim, J., Jang, J., Kim, H. K., & Cho, D. (2019) · Journal of Tissue Engineering · doi:10.1177/2041731418823382 · Cited by 141

3D cell printing of islet-laden pancreatic tissue-derived extracellular matrix bioink constructs for enhancing pancreatic functions

Kim, J., Shim, I. K., Hwang, D. G., Lee, Y. N., Kim, M., Kim, H., Kim, S.-W., Lee, S., Kim, S. C., Cho, D., et al. (2019) · Journal of Materials Chemistry B · doi:10.1039/c8tb02787k · Cited by 141

Genipin and EDC crosslinking of extracellular matrix hydrogel derived from human umbilical cord for neural tissue repair

Výborný, K., Vallová, J., Kočí, Z., Kekulová, K., Jiráková, K., Jendelová, P., Hodan, J., & Kubinová, Š. (2019) · Scientific Reports · doi:10.1038/s41598-019-47059-x · Cited by 140

Biomechanics and structure of the cornea: implications and association with corneal disorders

Ma, J., Wang, Y., Wei, P., & Jhanji, V. (2018) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2018.05.004 · Cited by 136

Decellularized brain matrix enhances macrophage polarization and functional improvements in rat spinal cord injury

Hong, J. Y., Seo, Y., Davaa, G., Kim, H., Kim, S. H., & Hyun, J. K. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.11.012 · Cited by 134

Intravascular ultrasound–guided vs angiography-guided drug-eluting stent implantation in complex coronary lesions: Meta-analysis of randomized trials

Bavishi, C., Sardar, P., Chatterjee, S., Khan, A. R., Shah, A., Ather, S., Lemos, P. A., Moreno, P., & Stone, G. W. (2016) · American Heart Journal · doi:10.1016/j.ahj.2016.10.008 · Cited by 133

A biologic scaffold–associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy

Wolf, M. T., Ganguly, S., Wang, T. L., Anderson, C. W., Sadtler, K., Narain, R., Cherry, C., Parrillo, A. J., Park, B. V., Wang, G., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aat7973 · Cited by 131

96 perfusable blood vessels to study vascular permeability in vitro

van Duinen, V., van den Heuvel, A., Trietsch, S. J., Lanz, H. L., van Gils, J. M., van Zonneveld, A. J., Vulto, P., & Hankemeier, T. (2017) · Scientific Reports · doi:10.1038/s41598-017-14716-y · Cited by 130

Decellularized Extracellular Matrix Derived from Porcine Adipose Tissue as a Xenogeneic Biomaterial for Tissue Engineering

Choi, Y. C., Choi, J. S., Kim, B. S., Kim, J. D., Yoon, H. I., & Cho, Y. W. (2012) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2012.0009 · Cited by 127

Wound healing models: A systematic review of animal and non-animal models

Sami, D. G., Heiba, H. H., & Abdellatif, A. (2018) · Wound Medicine · doi:10.1016/j.wndm.2018.12.001 · Cited by 126

Multilayered Electrospun Scaffolds for Tendon Tissue Engineering

Chainani, A., Hippensteel, K. J., Kishan, A. P., Garrigues, N. W., Ruch, D. S., Guilak, F., & Little, D. (2013) · Tissue Engineering Part A · doi:10.1089/ten.tea.2013.0165 · Cited by 123

Mesenchymal stromal cell-derived extracellular vesicles for regenerative therapy and immune modulation: Progress and challenges toward clinical application

Allan, D., Tieu, A., Lalu, M. M., & Burger, D. E. (2019) · Stem Cells Translational Medicine · doi:10.1002/sctm.19-0114 · Cited by 123

Functional Maturation of Human iPSC-based Cardiac Microphysiological Systems with Tunable Electroconductive Decellularized Extracellular Matrices

Tsui, J. H., Leonard, A., Camp, N. D., Long, J. T., Nawas, Z., Chavanachat, R., Smith, A. S. T., Choi, J. S., Dong, Z., Ahn, E. H., et al. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2021.120764 · Cited by 123

Myocardial matrix–polyethylene glycol hybrid hydrogels for tissue engineering

Grover, G. N., Rao, N., & Christman, K. L. (2013) · Nanotechnology · doi:10.1088/0957-4484/25/1/014011 · Cited by 122

Tissue-specific bioactivity of soluble tendon-derived and cartilage-derived extracellular matrices on adult mesenchymal stem cells

Rothrauff, B. B., Yang, G., & Tuan, R. S. (2017) · Stem Cell Research & Therapy · doi:10.1186/s13287-017-0580-8 · Cited by 122

The performance of decellularized adipose tissue microcarriers as an inductive substrate for human adipose-derived stem cells

Turner, A. E. B., Yu, C., Bianco, J., Watkins, J. F., & Flynn, L. E. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.03.026 · Cited by 122

Three-dimensional bioprinting of a full-thickness functional skin model using acellular dermal matrix and gelatin methacrylamide bioink

Jin, R., Cui, Y., Chen, H., Zhang, Z., Weng, T., Xia, S., Yu, M., Zhang, W., Shao, J., Yang, M., et al. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.07.012 · Cited by 121

A biological functional hybrid scaffold based on decellularized extracellular matrix/gelatin/chitosan with high biocompatibility and antibacterial activity for skin tissue engineering

Xu, J., Fang, H., Zheng, S., Li, L., Jiao, Z., Wang, H., Nie, Y., Liu, T., & Song, K. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.07.162 · Cited by 120

Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion

Yu, C., Kornmuller, A., Brown, C. F. C., Hoare, T. R., & Flynn, L. E. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.12.017 · Cited by 119

Carbon nanotube doped pericardial matrix derived electroconductive biohybrid hydrogel for cardiac tissue engineering

Roshanbinfar, K., Mohammadi, Z., Mesgar, A. S.-M., Dehghan, M. M., Oommen, O. P., Hilborn, J. G., & Engel, F. B. (2019) · Biomaterials Science · doi:10.1039/c9bm00434c · Cited by 118

Decellularized peripheral nerve supports Schwann cell transplants and axon growth following spinal cord injury

Cerqueira, S. R., Lee, Y., Cornelison, R., Mertz, M. W., Wachs, R. A., Schmidt, C. E., & Bunge, M. B. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.05.049 · Cited by 117

Crosslinkable Hydrogels Derived from Cartilage, Meniscus, and Tendon Tissue

Visser, J., Levett, P. A., Moller, N. C. R. T., Besems, J., Boere, K. W. M., van Rijen, M. H. P., de Grauw, J. C., Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2015) · Tissue Engineering Part A · doi:10.1089/ten.tea.2014.0362 · Cited by 114

Brain organoid formation on decellularized porcine brain ECM hydrogels

Simsa, R., Rothenbücher, T., Gürbüz, H., Ghosheh, N., Emneus, J., Jenndahl, L., Kaplan, D. L., Bergh, N., Serrano, A. M., & Fogelstrand, P. (2021) · PLOS ONE · doi:10.1371/journal.pone.0245685 · Cited by 114

Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering

Garrigues, N. W., Little, D., Sanchez‐Adams, J., Ruch, D. S., & Guilak, F. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35068 · Cited by 112

A high-frequency shear device for testing soft biological tissues

Arbogast, K. B., Thibault, K. L., Pinheiro, B. S., Winey, K. I., & Margulies, S. S. (1997) · Journal of Biomechanics · doi:10.1016/s0021-9290(97)00023-7 · Cited by 112

Rate of recovery in motor and sensory fibres of the radial nerve: clinical and electrophysiological aspects

Trojaborg, W. (1970) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.33.5.625 · Cited by 112

Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering

Carvalho, M. S., Silva, J. C., Udangawa, R. N., Cabral, J. M. S., Ferreira, F. C., da Silva, C. L., Linhardt, R. J., & Vashishth, D. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.01.127 · Cited by 111

Tunable Human Myocardium Derived Decellularized Extracellular Matrix for 3D Bioprinting and Cardiac Tissue Engineering

Basara, G., Ozcebe, S. G., Ellis, B. W., & Zorlutuna, P. (2021) · Gels · doi:10.3390/gels7020070 · Cited by 110

Porcine Lung-Derived Extracellular Matrix Hydrogel Properties Are Dependent on Pepsin Digestion Time

Pouliot, R. A., Young, B. M., Link, P. A., Park, H. E., Kahn, A. R., Shankar, K., Schneck, M. B., Weiss, D. J., & Heise, R. L. (2020) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2020.0042 · Cited by 108

Proteomic composition and immunomodulatory properties of urinary bladder matrix scaffolds in homeostasis and injury

Sadtler, K., Sommerfeld, S. D., Wolf, M. T., Wang, X., Majumdar, S., Chung, L., Kelkar, D. S., Pandey, A., & Elisseeff, J. H. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.05.002 · Cited by 108

Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury

Thompson, R. E., Pardieck, J., Smith, L. J., Kenny, P., Crawford, L., Shoichet, M. S., & Sakiyama‐Elbert, S. E. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.02.013 · Cited by 106

Mechanical Characterization of Vocal Fold Tissue: A Review Study

Miri, A. K. (2014) · Journal of Voice · doi:10.1016/j.jvoice.2014.03.001 · Cited by 106

Design and Characterization of an Injectable Tendon Hydrogel: A Novel Scaffold for Guided Tissue Regeneration in the Musculoskeletal System

Farnebo, S. J., Woon, C. Y.-L., Schmitt, T., Joubert, L., Kim, M. Y., Pham, H. M., & Chang, J. (2013) · Tissue Engineering Part A · doi:10.1089/ten.tea.2013.0207 · Cited by 105

Peripheral Nerve‐Derived Matrix Hydrogel Promotes Remyelination and Inhibits Synapse Formation

Zou, J., Liu, S., Sun, J., Yang, W., Xu, Y., Rao, Z., Jiang, B., Zhu, Q., Liu, X., Wu, J., et al. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201705739 · Cited by 105

Restoring Mucosal Barrier Function and Modifying Macrophage Phenotype with an Extracellular Matrix Hydrogel: Potential Therapy for Ulcerative Colitis

Keane, T. J., Dziki, J. L., Sobieski, E., Smoulder, A. L., Castleton, A. A., Turner, N. J., White, L. J., & Badylak, S. F. (2016) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjw149 · Cited by 103

3-D physiomimetic extracellular matrix hydrogels provide a supportive microenvironment for rodent and human islet culture

Jiang, K., Chaimov, D., Patel, S. N., Liang, J., Wiggins, S., Samojlik, M. M., Rubiano, A. M., Simmons, C. S., & Stabler, C. L. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.08.057 · Cited by 102

3D-Printed Extracellular Matrix/Polyethylene Glycol Diacrylate Hydrogel Incorporating the Anti-inflammatory Phytomolecule Honokiol for Regeneration of Osteochondral Defects

Zhu, S., Chen, P., Chen, Y., Li, M., Chen, C., & Lü, H. (2020) · The American Journal of Sports Medicine · doi:10.1177/0363546520941842 · Cited by 102

Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model

Ungerleider, J. L., Johnson, T. D., Hernandez, M. J., Elhag, D., Braden, R. L., Dzieciątkowska, M., Osborn, K. G., Hansen, K. C., Mahmud, E., & Christman, K. L. (2016) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2016.01.009 · Cited by 102

Development of Bioink from Decellularized Tendon Extracellular Matrix for 3D Bioprinting

Toprakhisar, B., Nadernezhad, A., Bakirci, E., Khani, N., Skvortsov, G. A., & Koc, B. (2018) · Macromolecular Bioscience · doi:10.1002/mabi.201800024 · Cited by 101

Biohybrid oxidized alginate/myocardial extracellular matrix injectable hydrogels with improved electromechanical properties for cardiac tissue engineering

Mousavi, A., Mashayekhan, S., Baheiraei, N., & Pourjavadi, A. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.03.097 · Cited by 100

A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration

Lih, E., Park, W., Park, K. W., Chun, S. Y., Kim, H., Joung, Y. K., Kwon, T. G., Hubbell, J. A., & Han, D. K. (2019) · ACS Central Science · doi:10.1021/acscentsci.8b00812 · Cited by 98

Preparation and characterization of pro-angiogenic gel derived from small intestinal submucosa

Wang, W., Zhang, X., Chao, N., Qin, T., Ding, W., Zhang, Y., Sang, J., & Luo, J. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.10.013 · Cited by 96

Extracellular Matrix Hydrogel Derived from Human Umbilical Cord as a Scaffold for Neural Tissue Repair and Its Comparison with Extracellular Matrix from Porcine Tissues

Kočí, Z., Výborný, K., Dubišová, J., Vacková, I., Jäger, A., Lunov, O., Jiráková, K., & Kubinová, Š. (2017) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2017.0089 · Cited by 96

Cell-free decellularized cartilage extracellular matrix scaffolds combined with interleukin 4 promote osteochondral repair through immunomodulatory macrophages: in vitro and in vivo preclinical study.

Tian, G., Jiang, S., Li, J.-Q., Wei, F., Li, X., Ding, Y., Yang, Z., Sun, Z., Zha, K.-K., Wang, F., et al. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.03.054 · Cited by 96

Synergistic Effects of Beta Tri‐Calcium Phosphate and Porcine‐Derived Decellularized Bone Extracellular Matrix in 3D‐Printed Polycaprolactone Scaffold on Bone Regeneration

Kim, J., Ahn, G., Kim, C., Lee, J., Lee, I., An, S., Yun, W., Kim, S., & Shim, J. (2018) · Macromolecular Bioscience · doi:10.1002/mabi.201800025 · Cited by 95

Clickable decellularized extracellular matrix as a new tool for building hybrid-hydrogels to model chronic fibrotic diseases in vitro

Petrou, C. L., D’Ovidio, T. J., Bölükbas, D. A., Taş, S., Brown, R. D., Allawzi, A. M., Lindstedt, S., Nozik‐Grayck, E., Stenmark, K. R., Wagner, D. E., et al. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00613k · Cited by 95

3D cell-printing of tendon-bone interface using tissue-derived extracellular matrix bioinks for chronic rotator cuff repair

Chae, S., Sun, Y., Choi, Y., Ha, D., Jeon, I., & Cho, D. (2020) · Biofabrication · doi:10.1088/1758-5090/abd159 · Cited by 94

Comparison of nonlinear mechanical properties of bovine articular cartilage and meniscus

Danso, E. K., Honkanen, J. T. J., Saarakkala, S. S., & Korhonen, R. K. (2013) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2013.09.015 · Cited by 93

Extracellular Vesicles: Interplay with the Extracellular Matrix and Modulated Cell Responses

Halawani, A. A., Mithieux, S. M., Yeo, G. C., Hosseini‐Beheshti, E., & Weiss, A. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063389 · Cited by 92

Blended electrospinning with human liver extracellular matrix for engineering new hepatic microenvironments

Grant, R., Hallett, J. M., Forbes, S. J., Hay, D. C., & Callanan, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-42627-7 · Cited by 91

Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence

Nagao, R. J., Xu, J. H., Luo, P., Xue, J., Wang, Y., Kotha, S. S., Zeng, W., Fu, X., Himmelfarb, J., & Zheng, Y. Y. (2016) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0213 · Cited by 90

A potential dermal substitute using decellularized dermis extracellular matrix derived bio-ink

Won, J.-Y., Lee, M., Kim, M., Min, K., Ahn, G., Han, J., Jin, S., Yun, W., & Shim, J. (2019) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2019.1575842 · Cited by 89

Protein-reactive nanofibrils decorated with cartilage-derived decellularized extracellular matrix for osteochondral defects

Kim, H. S., Mandakhbayar, N., Kim, H., Leong, K. W., & Yoo, H. S. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120214 · Cited by 88

Solubilized extracellular matrix from brain and urinary bladder elicits distinct functional and phenotypic responses in macrophages

Meng, F. W., Slivka, P. F., Dearth, C. L., & Badylak, S. F. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2014.12.044 · Cited by 87

Decellularized nerve matrix hydrogel scaffolds with longitudinally oriented and size-tunable microchannels for peripheral nerve regeneration

Rao, Z., Lin, T., Qiu, S., Zhou, J., Liu, S., Chen, S., Wang, T., Liu, X., Zhu, Q., Bai, Y., et al. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111791 · Cited by 87

Evaluation of Different Decellularization Protocols on the Generation of Pancreas-Derived Hydrogels

Gaetani, R., Aude, S., DeMaddalena, L. L., Strassle, H., Dzieciątkowska, M., Wortham, M., Bender, R. H. F., Nguyen-Ngoc, K.-V., Schmid-Schöenbein, G. W., George, S. C., et al. (2018) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2018.0180 · Cited by 87

Adult human heart slices are a multicellular system suitable for electrophysiological and pharmacological studies

Camelliti, P., Al‐Saud, S. A., Smolenski, R. T., Alayoubi, S., Bussek, A., Wettwer, E., Banner, N. R., Bowles, C. T., Yacoub, M. H., & Terracciano, C. M. (2011) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2011.06.018 · Cited by 86

Modulating in vivo degradation rate of injectable extracellular matrix hydrogels

Wassenaar, J. W., Braden, R. L., Osborn, K. G., & Christman, K. L. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02564h · Cited by 86

Fabrication and characterization of electrospun nanofibers composed of decellularized meniscus extracellular matrix and polycaprolactone for meniscus tissue engineering

Gao, S., Guo, W., Chen, M., Yuan, Z., Wang, M., Zhang, Y., Liu, S., Xi, T., & Guo, Q. (2017) · Journal of Materials Chemistry B · doi:10.1039/c6tb03299k · Cited by 86

Characterization of extracellular matrix modified poly(ε-caprolactone) electrospun scaffolds with differing fiber orientations for corneal stroma regeneration

Fernández‐Pérez, J., Kador, K. E., Lynch, A. P., & Ahearne, M. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.110415 · Cited by 85

Engineering cartilage tissue based on cartilage-derived extracellular matrix cECM/PCL hybrid nanofibrous scaffold

Feng, B., Ji, T.-J., Wang, X., Fu, W. E., Ye, L., Zhang, H., & Li, F. (2020) · Materials & Design · doi:10.1016/j.matdes.2020.108773 · Cited by 85

Physico-chemical, mechanical and cytotoxicity characterizations of Laponite®/alginate nanocomposite

Ghadiri, M., Chrzanowski, W., Lee, W., Fathi, A., Dehghani, F., & Rohanizadeh, R. (2013) · Applied Clay Science · doi:10.1016/j.clay.2013.08.049 · Cited by 84

Therapeutic effect of decellularized extracellular matrix-based hydrogel for radiation esophagitis by 3D printed esophageal stent

Ha, D.-H., Chae, S., Lee, J. Y., Kim, J. Y., Yoon, J., Sen, T., Lee, S.-W., Kim, H. J., Cho, J., & Cho, D. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120477 · Cited by 82

Enhanced decellularization technique of porcine dermal ECM for tissue engineering applications

Ventura, R. D., Padalhin, A. R., Park, C. M., & Lee, B. T. (2019) · Materials Science and Engineering: C · doi:10.1016/j.msec.2019.109841 · Cited by 82

Tissue-Specific Effects of Esophageal Extracellular Matrix

Keane, T. J., DeWard, A. D., Londoño, R., Saldin, L. T., Castleton, A. A., Carey, L. E., Nieponice, A., Lagasse, E., & Badylak, S. F. (2015) · Tissue Engineering Part A · doi:10.1089/ten.tea.2015.0322 · Cited by 80

Influence of residual composition on the structure and properties of extracellular matrix derived hydrogels

Claudio‐Rizo, J. A., Rangel-Argote, M., Castellano, L. E., Delgado, J., Mata‐Mata, J. L., & Mendoza‐Novelo, B. (2017) · Materials Science and Engineering C · doi:10.1016/j.msec.2017.05.118 · Cited by 80

Cardiac tissue engineering: current state-of-the-art materials, cells and tissue formation

Rodrigues, I. C. P., Kaasi, A., Filho, R. M., Jardini, A. L., & Gabriel, L. P. (2018) · Einstein (São Paulo) · doi:10.1590/s1679-45082018rb4538 · Cited by 80

Bioinspired electrospun dECM scaffolds guide cell growth and control the formation of myotubes

Smoak, M. M., Hogan, K. J., Grande-Allen, K. J., & Mikos, A. G. (2021) · Science Advances · doi:10.1126/sciadv.abg4123 · Cited by 80

Design and Characterization of Tissue-Specific Extracellular Matrix-Derived Microcarriers

Turner, A. E. B., & Flynn, L. E. (2011) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2011.0246 · Cited by 79

An intestinal model with a finger-like villus structure fabricated using a bioprinting process and collagen/SIS-based cell-laden bioink

Kim, W.-J., & Kim, G. (2020) · Theranostics · doi:10.7150/thno.41225 · Cited by 79

Multi-layered Free-form 3D Cell-printed Tubular Construct with Decellularized Inner and Outer Esophageal Tissue-derived Bioinks

Nam, H., Jeong, H., Jo, Y., Lee, J. Y., Ha, D., Kim, J. H., Chung, J. H., Cho, Y., Cho, D., Lee, S., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-64049-6 · Cited by 79

Cryogenic free-form extrusion bioprinting of decellularized small intestinal submucosa for potential applications in skin tissue engineering

Shi, L., Hu, Y., Ullah, M. W., Ullah, I., Ou, H., Zhang, W., Liming, X., & Zhang, X. (2019) · Biofabrication · doi:10.1088/1758-5090/ab15a9 · Cited by 78

Decellularized Disc Hydrogels for hBMSCs tissue-specific differentiation and tissue regeneration

Peng, Y., Qing, X., Lin, H., Huang, D., Li, J., Tian, S., Liu, S., Lv, X., Ma, K., Li, R., et al. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.03.014 · Cited by 78

Decellularization of porcine skeletal muscle extracellular matrix for the formulation of a matrix hydrogel: a preliminary study

Fu, Y., Fan, X., Tian, C., Luo, J., Zhang, Y., Deng, L., Qin, T., & Lv, Q. (2016) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12776 · Cited by 77

Efficacy of thermoresponsive, photocrosslinkable hydrogels derived from decellularized tendon and cartilage extracellular matrix for cartilage tissue engineering

Rothrauff, B. B., Coluccino, L., Gottardi, R., Ceseracciu, L., Scaglione, S., Goldoni, L., & Tuan, R. S. (2017) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2465 · Cited by 76

Three-Dimensional Vascularized Lung Cancer-on-a-Chip with Lung Extracellular Matrix Hydrogels for In Vitro Screening

Park, S. U., Kim, T. H., Kim, S. H., You, S., & Jung, Y. (2021) · Cancers · doi:10.3390/cancers13163930 · Cited by 76

Production and evaluation of decellularized extracellular matrix hydrogel for cartilage regeneration derived from knee cartilage

Bordbar, S., Bakhshaiesh, N. L., Khanmohammadi, M., Sayahpour, F. A., Alini, M., & Eslaminejad, M. B. (2020) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36871 · Cited by 75

Printing 3D vagina tissue analogues with vagina decellularized extracellular matrix bioink

Hou, C., Zheng, J., Li, Z., Qi, X., Tian, Y., Zhang, M., Zhang, J., & Huang, X. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.03.070 · Cited by 75

Decellularized hepatic extracellular matrix hydrogel attenuates hepatic stellate cell activation and liver fibrosis

Hussein, K. H., Park, K.-M., Yu, L., Kwak, H.-H., & Woo, H.-M. (2020) · Materials Science and Engineering: C · doi:10.1016/j.msec.2020.111160 · Cited by 75

Small intestine submucosa and mesenchymal stem cells composite gel for scarless vocal fold regeneration

Choi, J. W., Park, J. K., Chang, J. W., Kim, D. Y., Kim, M. S., Shin, Y. S., & Kim, C. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.03.008 · Cited by 74

Aligned nanofibers of decellularized muscle ECM support myogenic activity in primary satellite cells in vitro

Patel, K. H., Dunn, A. J., Talovic, M., Haas, G. J., Marcinczyk, M., Elmashhady, H., Kalaf, E. A. G., Sell, S. A., & Garg, K. (2019) · Biomedical Materials · doi:10.1088/1748-605x/ab0b06 · Cited by 74

Matrix-bound nanovesicles prevent ischemia-induced retinal ganglion cell axon degeneration and death and preserve visual function

van der Merwe, Y., Faust, A. E., Sakalli, E. T., Westrick, C. C., Hussey, G. S., Chan, K. C., Conner, I. P., Fu, V. L. N., Badylak, S. F., & Steketee, M. B. (2019) · Scientific Reports · doi:10.1038/s41598-019-39861-4 · Cited by 74

Decellularized Skin Extracellular Matrix (dsECM) Improves the Physical and Biological Properties of Fibrinogen Hydrogel for Skin Bioprinting Applications

Jorgensen, A. M., Chou, Z., Gillispie, G. J., Lee, S. J., Yoo, J. J., Söker, S., & Atala, A. (2020) · Nanomaterials · doi:10.3390/nano10081484 · Cited by 74

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Rao, N., Roth, G. A., Tierney, M. T., Ungerleider, J. L., Braden, R. L., Sacco, A., & Christman, K. L. (2017) · ACS Nano · doi:10.1021/acsnano.7b00093 · Cited by 73

Human decellularized adipose matrix derived hydrogel assists mesenchymal stem cells delivery and accelerates chronic wound healing

Chen, Z., Zhang, B., Shu, J., Wang, H., Han, Y., Zeng, Q., Chen, Y., Xi, J., Tao, R., Pei, X., et al. (2020) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37133 · Cited by 73

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Wang, C., Li, G., Cui, K., Chai, Z., Huang, Z., Liu, Y., Chen, S., Huang, H., Zhang, K., Han, Z., et al. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.12.055 · Cited by 72

Extracellular matrix particle-glycosaminoglycan composite hydrogels for regenerative medicine applications

Beachley, V., Ma, G., Papadimitriou, C., Gibson, M., Corvelli, M., & Elisseeff, J. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36218 · Cited by 72

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Smith, E. L., Kanczler, J. M., Gothard, D., Roberts, C., Wells, J. A., White, L. J., Qutachi, O., Sawkins, M. J., Peto, H., Rashidi, H., et al. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.06.011 · Cited by 71

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Brown-Etris, M., Milne, C. T., & Hodde, J. P. (2018) · Journal of Tissue Viability · doi:10.1016/j.jtv.2018.11.001 · Cited by 71

Kidney extracellular matrix hydrogel enhances therapeutic potential of adipose-derived mesenchymal stem cells for renal ischemia reperfusion injury

Zhou, C., Zhou, L., Liu, J., Xu, L., Xu, Z., Chen, Z., Ge, Y., Zhao, F., Wu, R., Wang, X., et al. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.07.056 · Cited by 71

Bio-artificial tongue with tongue extracellular matrix and primary taste cells

Lee, J. S., Cho, A., Jin, Y., Kim, J., Kim, S., & Cho, S. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.019 · Cited by 70

Human articular cartilage repair: Sources and detection of cytotoxicity and genotoxicity in photo-crosslinkable hydrogel bioscaffolds

Lee, C. Y., O’Connell, C. D., Onofrillo, C., Choong, P., Bella, C. D., & Duchi, S. (2019) · Stem Cells Translational Medicine · doi:10.1002/sctm.19-0192 · Cited by 70

Effect of decellularized adipose tissue particle size and cell density on adipose-derived stem cell proliferation and adipogenic differentiation in composite methacrylated chondroitin sulphate hydrogels

Brown, C. F. C., Jing, Y., Han, T. T. Y., Marecak, D. M., Amsden, B. G., & Flynn, L. E. (2015) · Biomedical Materials · doi:10.1088/1748-6041/10/4/045010 · Cited by 70

Injectable, porous, biohybrid hydrogels incorporating decellularized tissue components for soft tissue applications

Zhu, Y., Hideyoshi, S., Jiang, H., Matsumura, Y., Dziki, J. L., LoPresti, S. T., Huleihel, L., Faria, G. N. F., Fuhrman, L. C., Lodono, R., et al. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.04.003 · Cited by 69

Adipose tissue‐derived extracellular matrix hydrogels as a release platform for secreted paracrine factors

van Dongen, J. A., Getova, V. E., Brouwer, L. A., Liguori, G. R., Sharma, P. K., Stevens, H. P. J. D., van der Lei, B., & Harmsen, M. C. (2019) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2843 · Cited by 68

Fabrication and Characterization of Electrospun Decellularized Muscle-Derived Scaffolds

Smoak, M. M., Han, A., Watson, E., Kishan, A. P., Grande-Allen, K. J., Cosgriff‐Hernandez, E., & Mikos, A. G. (2019) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2018.0339 · Cited by 68

Complex bile duct network formation within liver decellularized extracellular matrix hydrogels

Lewis, P. L., Su, J., Yan, M., Meng, F., Glaser, S. S., Alpini, G. D., Green, R. M., Sosa-Pineda, B., & Shah, R. N. (2018) · Scientific Reports · doi:10.1038/s41598-018-30433-6 · Cited by 68

Application of UVA-riboflavin crosslinking to enhance the mechanical properties of extracellular matrix derived hydrogels

Ahearne, M., & Coyle, A. (2015) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2015.09.035 · Cited by 66

Artificial testis: a testicular tissue extracellular matrix as a potential bio-ink for 3D printing

Bashiri, Z., Amiri, I., Gholipourmalekabadi, M., Falak, R., Asgari, H. R., Maki, C. B., Moghaddaszadeh, A., & Koruji, M. (2021) · Biomaterials Science · doi:10.1039/d0bm02209h · Cited by 66

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Chen, S., Du, Z., Zou, J., Qiu, S., Rao, Z., Liu, S., Sun, X., Xu, Y., Zhu, Q., Liu, X., et al. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b01066 · Cited by 66

Effect of Hierarchical Scaffold Consisting of Aligned dECM Nanofibers and Poly(lactide-co-glycolide) Struts on the Orientation and Maturation of Human Muscle Progenitor Cells

Lee, H., Kim, W.-J., Lee, J., Yoo, J. J., Kim, G., & Lee, S. J. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b12639 · Cited by 65

Construction of multifunctional porcine acellular dermal matrix hydrogel blended with vancomycin for hemorrhage control, antibacterial action, and tissue repair in infected trauma wounds

Cai, D., Chen, S., Wu, B., Chen, J., Tao, D., Li, Z., Dong, Q., Zou, Y., Chen, Y., Bi, C., et al. (2021) · Materials Today Bio · doi:10.1016/j.mtbio.2021.100127 · Cited by 65

Nerve‐specific, xenogeneic extracellular matrix hydrogel promotes recovery following peripheral nerve injury

Prest, T. A., Yeager, E. A., LoPresti, S. T., Žygelytė, E., Martin, M. J., Dong, L., Gibson, A., Olutoye, O. O., Brown, B. N., & Cheetham, J. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36235 · Cited by 64

Long-term retention of ECM hydrogel after implantation into a sub-acute stroke cavity reduces lesion volume

Ghuman, H., Gerwig, M., Nicholls, F. J., Liu, J. R., Donnelly, J., Badylak, S. F., & Modo, M. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.09.011 · Cited by 63

Kidney decellularized extracellular matrix hydrogels: Rheological characterization and human glomerular endothelial cell response to encapsulation

Su, J. L.-S., Satchell, S. C., Shah, R. N., & Wertheim, J. A. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36439 · Cited by 63

Injectable extracellular matrix hydrogel developed using porcine articular cartilage

Kwon, J. S., Yoon, S. M., Shim, S. W., Park, J. H., Min, K. J., Oh, H. J., Kim, J. H., Kim, Y. J., Yoon, J. J., Choi, B. H., et al. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.06.023 · Cited by 63

Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Ju, Y., Hu, Y., Pu, Y., Xie, X., & Fang, B. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100522 · Cited by 471

Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Liu, J., Song, Q., Yin, W., Li, C., An, N., Le, Y., Wang, Q., Feng, Y., Hu, Y., & Wang, Y. (2025) · Exploration · doi:10.1002/exp.20230078 · Cited by 140

Injectable smart stimuli-responsive hydrogels: pioneering advancements in biomedical applications

Liu, J., Du, C., Huang, W., & Lei, Y. (2023) · Biomaterials Science · doi:10.1039/d3bm01352a · Cited by 133

Progress in biomaterials inspired by the extracellular matrix

Chen, Z., Du, C., Liu, S., Liu, J., Yang, Y., Dong, L., Zhao, W., Huang, W., & Lei, Y. (2024) · Giant · doi:10.1016/j.giant.2024.100323 · Cited by 140

Decellularized extracellular matrix-based composite scaffolds for tissue engineering and regenerative medicine

Xu, P., Kankala, R. K., Wang, S., & Chen, A. (2024) · Regenerative Biomaterials · doi:10.1093/rb/rbad107 · Cited by 129

The intestinal microbiome and surgical disease

Krezalek, M. A., Skowron, K. B., Guyton, K. L., Shakhsheer, B. A., Hyoju, S. K., & Alverdy, J. C. (2016) · Current Problems in Surgery · doi:10.1067/j.cpsurg.2016.06.001 · Cited by 35

Extracellular‐Matrix‐Based Materials from Decellularized Tissue: Opportunities, Challenges, and Future Directions in Regenerative Medicine

Laude, M., Kolliopoulos, V., Mikos, A. G., White, L. J., & Cosgriff‐Hernandez, E. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202502107 · Cited by 30

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Golebiowska, A. A., Intravaia, J. T., Sathe, V. M., Kumbar, S. G., & Nukavarapu, S. P. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.09.017 · Cited by 236

Recent development and biomedical applications of decellularized extracellular matrix biomaterials

Yao, Q., Zheng, Y., Lan, Q.-H., Kou, L., Xu, H., & Zhao, Y. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.109942 · Cited by 178

Functional design and application strategies based on decellularized extracellular matrix for tissue regeneration

Zhang, T., Xu, H., Hao, H., & An, M. (2026) · Applied Materials Today · doi:10.1016/j.apmt.2026.103444