The DOI matches its Crossref record; 170 of the 174 references it cites were found in a registry or an index.
Biosensors for real-time in vivo measurements
Abstract
The current status of sensors capable of continuous measurement of analytes in biological media is reviewed. This review containing 173 references deals with devices whose use in single cells, tissue slices, animal models and humans has been demonstrated. In addition to sensors specific for glucose, lactate, glutamate, pyruvate, choline and acetylcholine, insights obtained from monitoring nitric oxide, Na(+), K(+), Ca(2+), and dopamine are presented. Performance criteria for sensor performance are described as is the subject of biosensor calibration. Biocompatibility issues are dealt with in some detail as is the status of continuous blood glucose monitoring in humans.
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“As described earlier, the use of mediators to shuttle electrons between the enzyme and the electrode can also minimize the impact of interfering species by lowering the working potential required to oxidize hydrogen peroxide.56,58,62”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [58]
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Xiang, L., Lin, Y., Yu, P., Su, L., & Mao, L. (2007) · Electrochimica Acta · doi:10.1016/j.electacta.2006.11.040 · Cited by 89
Metadata
- Authors
- Wilson, G. S., & Gifford, R.
- Affiliations
- University of Kansas (US)
- Corresponding author
- Wilson, George S.
- ORCID
- Wilson, George S.
- Venue
- Biosensors and Bioelectronics
- Publisher
- Elsevier BV
- Published
- 2005-06
- Volume
- 20
- Issue
- 12
- Pages
- 2388-2403
- ISSN
- 0956-5663 (ISSN-L)
- OpenAlex
- W2090868198
- Cited by
- 660
- References
- 174
- Citations by year
- 2026: 17 · 2025: 21 · 2024: 14 · 2023: 16 · 2022: 17 · 2021: 13 · 2020: 23 · 2019: 27 · 2018: 36 · 2017: 25 · 2016: 37 · 2015: 39 · 2014: 40 · 2013: 50 · 2012: 52
- FWCI
- 2.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biosensors and Bioelectronics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Electrochemical sensors and biosensors
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Chemistry and Sensors
- Physical Sciences › Chemistry › Electrochemistry › Electrochemical Analysis and Applications
- Keywords
- biosensors, in vivo monitoring, glucose sensor, lactate sensor, glutamate sensor, nitric oxide sensor, ion sensors, dopamine sensor, sensor calibration, biocompatibility, continuous glucose monitoring
- MeSH terms
- Blood Glucose, Equipment Design, Transducers, Blood Glucose Self-Monitoring, Biosensing Techniques, Monitoring, Ambulatory, Cell Culture Techniques, Prostheses and Implants
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