Vascular endothelial growth factor and dexamethasone release from nonfouling sensor coatings affect the foreign body response

Norton, L.W.; Koschwanez, H.E.; Wisniewski, N.A.; Klitzman, B.; Reichert, W.M.

doi:10.1002/jbm.a.31088

Cited by 128Hydrogels: synthesis, properties, applicationsTissue Engineering and Regenerative MedicinePolymer Surface Interaction Studies

Vascular endothelial growth factor and dexamethasone release from nonfouling sensor coatings affect the foreign body response

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Norton, L.W., Koschwanez, H.E., Wisniewski, N.A., Klitzman, B., Reichert, W.M.·2007·Journal of Biomedical Materials Research Part A

DOI 10.1002/jbm.a.31088PMC PMC4070388

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Abstract

Vascular endothelial growth factor (VEGF) and dexamethasone (DX) release from hydrogel coatings were examined as a means to modify tissue inflammation and induce angiogenesis. Antibiofouling hydrogels for implantable glucose sensor coatings were prepared from 2‐hydroxyethyl methacrylate, N‐vinyl pyrrolidinone, and polyethylene glycol. Microdialysis sampling was used to test the effect of the hydrogel coating on glucose recovery. VEGF‐releasing hydrogel‐coated fibers increased vascularity and inflammation in the surrounding tissue after 2 weeks of implantation compared to hydrogel‐coated fibers. DX‐releasing hydrogel‐coated fibers reduced inflammation compared to hydrogel‐coated fibers and had reduced capsule vascularity compared to VEGF‐releasing hydrogel‐coated fibers. Hydrogels that released both VEGF and DX simultaneously also showed reduced inflammation at 2 weeks implantation; however, no enhanced vessel formation was observed indicating that the DX diminished the VEGF effect. At 6 weeks, there were no detectable differences between drug‐releasing hydrogel‐coated fibers and control fibers. From this study, hydrogel drug release affected initial events of the foreign body response with DX inhibiting VEGF, but once the drug depot was exhausted these effects disappeared. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res, 2007

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Norton et al. observed the expected increase in vascularization due to VEGF but no decrease in local inflammation from dexamethasone release.
“Norton et al. carefully examined the tissue response to VEGF-, DX-, and VEGF/DX-releasing hydrogels in a rat subcutaneous model,191 observing the expected increase in vascularization due to VEGF but no decrease in local inflammation from DX release.”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [191]
Norton et al. observed no real benefit in reducing the inflammatory response using dexamethasone-releasing PLGA microspheres after 2 or 6 weeks in rat subcutaneous tissue.
“Norton et al. observed no real benefit in reducing the inflammatory response using DX-releasing PLGA microspheres after 2 or 6 weeks in rat subcutaneous tissue.191”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [191]

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Polymeric system for dual growth factor delivery
Richardson, T. P., Peters, M. C., Ennett, A. B., & Mooney, D. J. (2001) · Nature Biotechnology · doi:10.1038/nbt1101-1029 · Cited by 1,753 · see citing works
Biomaterials: Where We Have Been and Where We Are Going
Ratner, B. D., & Bryant, S. J. (2004) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.6.040803.140027 · Cited by 1,507 · see citing works
Biological Responses to Materials
Anderson, J. M. (2001) · Annual Review of Materials Research · doi:10.1146/annurev.matsci.31.1.81 · Cited by 1,465 · see citing works
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
Barleon, B., Sozzani, S., Zhou, D., Weich, H., Mantovani, A., & Marmé, D. (1996) · Blood · doi:10.1182/blood.v87.8.3336.bloodjournal8783336 · Cited by 1,350 · see citing works
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
Benjamin, L. E., Golijanin, D., Itin, A., Pode, D., & Keshet, E. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5028 · Cited by 1,234 · see citing works
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
Cursiefen, C., Chen, L., Borges, L. P., Jackson, D. G., Cao, J., Radziejewski, C. H., D'Amore, P. A., Dana, M. R., Wiegand, S. J., & Streilein, J. W. (2004) · Journal of Clinical Investigation · doi:10.1172/jci20465 · Cited by 1,053 · see citing works
Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues
Pusztaszeri, M. P., Seelentag, W., & Bosman, F. T. (2006) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.4a6514.2005 · Cited by 865 · see citing works
The biology of PECAM-1.
Newman, P. J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119129 · Cited by 671 · see citing works
Biosensors for real-time in vivo measurements
Wilson, G. S., & Gifford, R. (2005) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2004.12.003 · Cited by 660 · see citing works
Neovascularization of synthetic membranes directed by membrane microarchitecture
Brauker, J. H., Carr‐Brendel, V. E., Martinson, L. A., Crudele, J., Johnston, W. D., & Johnson, R. C. (1995) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820291208 · Cited by 517 · see citing works
Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
Bungay, P. M., Morrison, P. F., & Dedrick, R. L. (1990) · Life Sciences · doi:10.1016/0024-3205(90)90043-q · Cited by 507 · see citing works
Polymeric Growth Factor Delivery Strategies for Tissue Engineering
Chen, R. R., & Mooney, D. J. (2003) · Pharmaceutical Research · doi:10.1023/a:1025034925152 · Cited by 435 · see citing works
VEGF164-mediated Inflammation Is Required for Pathological, but Not Physiological, Ischemia-induced Retinal Neovascularization
Ishida, S., Usui, T., Yamashiro, K., Kaji, Y., Amano, S., Ogura, Y., Hida, T., Oguchi, Y., Ambati, J., Miller, J. W., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20022027 · Cited by 421 · see citing works
Subcutaneous glucose predicts plasma glucose independent of insulin: implications for continuous monitoring
Rebrin, K., Steil, G. M., van Antwerp, W. P., & Mastrototaro, J. J. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.3.e561 · Cited by 367 · see citing works
Characterization of implantable biosensor membrane biofouling
Wisniewski, N. A., Moussy, F. G., & Reichert, W. M. (2000) · Fresenius Journal of Analytical Chemistry · doi:10.1007/s002160051556 · Cited by 351 · see citing works
Self-citation
Sustained Local Delivery of Dexamethasone by a Novel Intravascular Eluting Stent to Prevent Restenosis in the Porcine Coronary Injury Model
Lincoff, A. M., Furst, J., Ellis, S. G., Tuch, R. J., & Topol, E. J. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00584-0 · Cited by 282 · see citing works
Angiogenic factors stimulate mast-cell migration
Gruber, B., Marchese, M., & Kew, R. R. (1995) · Blood · doi:10.1182/blood.v86.7.2488.2488 · Cited by 268 · see citing works
Materials for protein delivery in tissue engineering
Baldwin, S. P., & Saltzman, W. M. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(98)00021-0 · Cited by 241 · see citing works
Receptor-mediated cellular entry of nuclear localizing anti-DNA antibodies via myosin 1.
Yanase, K., Smith, R. M., Puccetti, A., Jarett, L., & Madaio, M. P. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119517 · Cited by 239 · see citing works
Long-term engraftment of hepatocytes transplanted on biodegradable polymer sponges
Mooney, D. J., Sano, K., Kaufmann, P. M., Majahod, K., Schloo, B. L., Vacanti, J. P., & Langer, R. (1997) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19971205)37:3 · Cited by 233 · see citing works
Migration of leukocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes
Müller, W. A., & Randolph, G. J. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.5.698 · Cited by 204 · see citing works
In vivo evaluation of a dexamethasone/PLGA microsphere system designed to suppress the inflammatory tissue response to implantable medical devices
Hickey, T., Kreutzer, D. L., Burgess, D. J., & Moussy, F. G. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.10016 · Cited by 187 · see citing works
The unfolding tale of PECAM‐1
Jackson, D. E. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00224-2 · Cited by 175 · see citing works
VEGF 164(165) as the Pathological Isoform: Differential Leukocyte and Endothelial Responses through VEGFR1 and VEGFR2
Usui, T., Ishida, S., Yamashiro, K., Kaji, Y., Poulaki, V., Moore, J., Moore, T., Amano, S., Horikawa, Y., Dartt, D. A., et al. (2004) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.03-0106 · Cited by 161 · see citing works
VEGF deprivation-induced apoptosis is a component of programmed capillary regression
Meeson, A. P., Argilla, M., Ko, K. A., Witte, L., & Lang, R. A. (1999) · Development · doi:10.1242/dev.126.7.1407 · Cited by 147 · see citing works
The Microcirculation and Inflammation: Site of Action for Glucocorticoids
Perretti, M., & Ahluwalia, A. (2000) · Microcirculation · doi:10.1111/j.1549-8719.2000.tb00117.x · Cited by 146 · see citing works
Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty.
Villa, A. E., Guzmán, L. A., Chen, W., Golomb, G., Levy, R. J., & Topol, E. J. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117078 · Cited by 142 · see citing works
The sequence of events in the regression of corneal capillaries.
Ausprunk, D. H., Falterman, K., & Folkman, J. (1978) · PubMed · Cited by 140 · see citing works
Angiogenesis with biomaterial-based drug- and cell-delivery systems
Patel, Z. S., & Mikos, A. G. (2004) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856204774196117 · Cited by 138 · see citing works
Decreased analyte transport through implanted membranes: Differentiation of biofouling from tissue effects
Wisniewski, N., Klitzman, B. M., Miller, B., & Reichert, W. M. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(20011215)57:4 · Cited by 120 · see citing works
Self-citation
Characterization by microdialysis of intracellular glucose level in subcutaneous tissue in humans
Jansson, P., Fowelin, J., Smith, U., & Lönnroth, P. (1988) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1988.255.2.e218 · Cited by 119 · see citing works
Long-term continuous glucose monitoring with microdialysis in ambulatory insulin-dependent diabetic patients
Bolinder, J., Ungerstedt, U., & Arner, P. (1993) · The Lancet · doi:10.1016/0140-6736(93)92063-y · Cited by 105 · see citing works
In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings
Norton, L. W., Tegnell, E., Toporek, S. S., & Reichert, W. M. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.069 · Cited by 104 · see citing works
Self-citation
Assessment of subcutaneous glucose concentration: validation of the wick technique as a reference for implanted electrochemical sensors in normal and diabetic dogs
Fischer, U., Ertle, R., Abel, P., Rebrin, K., Brunstein, E., von Dorsche, H. H., & Freyse, E. (1987) · Diabetologia · doi:10.1007/bf00295878 · Cited by 104 · see citing works
Molecular Mechanisms of In-Stent Restenosis and Approach to Therapy with Eluting Stents
Indolfi, C. (2003) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(03)00038-0 · Cited by 101 · see citing works
How Fibroblasts and Giant Cells Encapsulate Implants: Considerations in Design of Glucose Sensors
Woodward, S. C. (1982) · Diabetes Care · doi:10.2337/diacare.5.3.278 · Cited by 89 · see citing works
Vascular Endothelial Growth Factor-Releasing Scaffolds Enhance Vascularization and Engraftment of Hepatocytes Transplanted on Liver Lobes
Kedem, A., Perets, A., Gamlieli‐Bonshtein, I., Dvir‐Ginzberg, M., Mizrahi, S. S., & Cohen, S. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.715 · Cited by 88 · see citing works
Hyperstimulation and a Gonadotropin-Releasing Hormone Agonist Modulate Ovarian Vascular Permeability by Altering Expression of the Tight Junction Protein Claudin-5
Kitajima, Y., Endo, T., Nagasawa, K., Manase, K., Honnma, H., Baba, T., Hayashi, T., Chiba, H., Sawada, N., & Saito, T. (2005) · Endocrinology · doi:10.1210/en.2005-0700 · Cited by 88 · see citing works
Enhancement of implantable glucose sensor function in vivo using gene transfer-induced neovascularization
Klueh, U., Dorsky, D. I., & Kreutzer, D. L. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.04.017 · Cited by 87 · see citing works
Feasibility of Continuous Long-Term Glucose Monitoring from a Subcutaneous Glucose Sensor in Humans
Gilligan, B. C., Shults, M., Rhodes, R. K., Jacobs, P. G., Brauker, J. H., Pintar, T. J., & Updike, S. J. (2004) · Diabetes Technology & Therapeutics · doi:10.1089/152091504774198089 · Cited by 71 · see citing works
Encapsulation of proteins for improved delivery
Putney, S. D. (1998) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(98)80133-6 · Cited by 68 · see citing works
Assessment of Vascularity in Histological Sections: Effects of Methodology and Value as an Index of Angiogenesis in Breast Tumours
Schor, A. M., Pendleton, N., Pazouki, S., Smither, R. L., Morris, J., Lessan, K., Heerkens, E. H. J., Chandrachud, L. M., Carmichael, G., Adi, M. M., et al. (1998) · The Histochemical Journal · doi:10.1023/a:1003437619956 · Cited by 65 · see citing works
Effect on intimal hyperplasia of dexamethasone released from coated metal stents compared with non-coated stents in canine femoral arteries
Strecker, E.-P. K., Gabelmann, A., Boos, I. B. L., Lucas, C., Xu, Z., Haberstroh, J., Freudenberg, N., Stricker, H., Langer, M., & BETZ, E. (1998) · CardioVascular and Interventional Radiology · doi:10.1007/s002709900309 · Cited by 56 · see citing works
Vascularizing the tissue surrounding a model biosensor: how localized is the effect of a subcutaneous infusion of vascular endothelial growth factor (VEGF)?
Ward, W. K., Quinn, M. J., Wood, M. D., Tiekotter, K. L., Pidikiti, S., & Gallagher, J. A. (2003) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(03)00180-5 · Cited by 55 · see citing works
A comparison of the adhesion of mammalian cells andStaphylococcus epidermidis on fibronectin-modified polymer surfaces
Dexter, S. J., Pearson, R. G., Davies, M. C., C�mara, M., & Shakesheff, K. M. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200108)56:2 · Cited by 35 · see citing works
The role of continuous glucose sensors in diabetes care
Garg, S. K., Hoff, H. K., & Chase, H. P. (2004) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2004.01.001 · Cited by 32 · see citing works
So-called biological dressing effects of cultured epidermal sheets are mediated by the production of EGF family, TGF-β and VEGF
Shirakata, Y., Tokumaru, S., Yamasaki, K., Sayama, K., & Hashimoto, K. (2003) · Journal of Dermatological Science · doi:10.1016/s0923-1811(03)00103-8 · Cited by 30 · see citing works
Selective Apoptosis of Luteal Endothelial Cells in Dexamethasone-Treated Rats Leads to Ischemic Necrosis of Luteal Tissue1
Gaytán, F., Morales, C., Bellido, C., & Sánchez‐Criado, J. E. (2002) · Biology of Reproduction · doi:10.1095/biolreprod66.1.232 · Cited by 29 · see citing works
Differential expression of VEGF receptors in adrenal atrophy induced by dexamethasone: a protective role of ACTH
Mallet, C., Féraud, O., Ouengue-Mbélé, G., Gaillard, I., Sappay, N., Vittet, D., & Vilgrain, I. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00450.2001 · Cited by 28 · see citing works
Glucocorticoid-Regulated VEGF Expression in Ischemic Skeletal Muscle
Halaby, I. A., Lyden, S. P., Davies, M. G., Roztocil, E., Salamone, L., Brooks, A. I., Green, R. M., Federoff, H. J., & Bowers, W. J. (2002) · Molecular Therapy · doi:10.1006/mthe.2002.0539 · Cited by 26 · see citing works
Use of vascular endothelial cell growth factor gene transfer to enhance implantable sensor function in vivo
Klueh, U., Dorsky, D. I., & Kreutzer, D. L. (2003) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.20041 · Cited by 26 · see citing works
Glucose uptake and flux through phosphofructokinase in wounded rat skeletal muscle
Förster, J., Morris, A. S., Shearer, J. D., Mastrofrancesco, B., Inman, K. C., Lawler, R. G., Bowen, W. D., & Caldwell, M. D. (1989) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1989.256.6.e788 · Cited by 24 · see citing works
Biomaterials Community Examines Biosensor Biocompatibility
Moussy, F. G., & Reichert, W. M. (2000) · Diabetes Technology & Therapeutics · doi:10.1089/15209150050194341 · Cited by 18 · see citing works
Self-citation
Five‐Year Follow‐Up of a Bipolar Steroid‐Eluting Ventricular Pacing Lead
Schwaab, B., Fröhlig, G., BERG, M., SCHWERDT, H., & Schieffer, H. J. (1999) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1999.tb00604.x · Cited by 15 · see citing works
Tenascin and microvessel stromal changes in patients with non-Hodgkin's lymphoma are isolated to the sites of disease and vary in correlation to disease activity
Rizzieri, D. A., Wadleigh, M., Wikstrand, C. J., Mann, K. P., Şen, F., Peterson, B. L., Niedzwiecki, D., Proia, A. D., & Bigner, D. D. (2005) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428190500158060 · Cited by 7 · see citing works
Water-soluble treatments to enhance glucose permeability of protein-resistant polymer overlayers
Shin, B. C., Wisniewski, N. A., & Reichert, W. M. (2001) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856201300194216 · Cited by 5 · see citing works
Self-citation
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Wiggins (2001) · doi:10.1002/1097-4636(2001)58:3
Self-citation

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[15]Weast RC, editor. CRC Handbook of Chemistry and Physics. Boca Raton, FL: CRC Press; 1984. [Google Scholar]

Sorted by citations

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Franz, S., Rammelt, S., Scharnweber, D., & Simon, J. C. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.05.078 · Cited by 1,391 · see citing works
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Wang, Y., Vaddiraju, S., Gu, B., Papadimitrakopoulos, F., & Burgess, D. J. (2015) · Journal of Diabetes Science and Technology · doi:10.1177/1932296815601869 · Cited by 107 · see citing works
Polymeric “smart” coatings to prevent foreign body response to implantable biosensors
Wang, Y., Papadimitrakopoulos, F., & Burgess, D. J. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.12.028 · Cited by 100 · see citing works
Controllable mineral coatings on PCL scaffolds as carriers for growth factor release
Suárez-González, D., Barnhart, K., Migneco, F., Flanagan, C. L., Hollister, S. J., & Murphy, W. L. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.09.095 · Cited by 93 · see citing works
In Vivo Chemical Sensors: Role of Biocompatibility on Performance and Utility
Soto, R. J., Hall, J. R., Brown, M. D., Taylor, J. B., & Schoenfisch, M. H. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04251 · Cited by 85 · see citing works
Biological Response to Carbon-Family Nanomaterials: Interactions at the Nano-Bio Interface
Rahmati, M., & Mozafari, M. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00004 · Cited by 84 · see citing works
Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques
Khan, F., Tare, R. S., Kanczler, J. M., Oreffo, R. O. C., & Bradley, M. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2009.11.101 · Cited by 81 · see citing works
Exercise training prevents hyperinsulinemia, muscular glycogen loss and muscle atrophy induced by dexamethasone treatment
Barel, M., Perez, O. A. B., Giozzet, V. A. G., Rafacho, A., Bosqueiro, J. R., & Amaral, S. L. (2009) · European Journal of Applied Physiology · doi:10.1007/s00421-009-1272-6 · Cited by 81 · see citing works
Antifibrotic strategies for medical devices
Welch, N. G., Winkler, D. A., & Thissen, H. W. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.06.008 · Cited by 78 · see citing works
Tuning drug delivery from conducting polymer films for accurately controlled release of charged molecules
Boehler, C., Oberueber, F., & Asplund, M. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.05.017 · Cited by 68 · see citing works
The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants
Nichols, S. P., Koh, A., Brown, N. L., Rose, M. B., Sun, B., Slomberg, D. L., Riccio, D. A., Klitzman, B., & Schoenfisch, M. H. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.05.053 · Cited by 67 · see citing works
Self-citation
Foreign body response to subcutaneous biomaterial implants in a mast cell-deficient Kitw-Sh murine model
Avula, M., Rao, A. N., McGill, L. D., Grainger, D. W., & Solzbacher, F. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.12.056 · Cited by 67 · see citing works
Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation
Takahashi, H., Wang, Y., & Grainger, D. W. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.08.019 · Cited by 58 · see citing works
Modeling the relative impact of capsular tissue effects on implanted glucose sensor time lag and signal attenuation
Novak, M. T., Yuan, F., & Reichert, W. M. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4097-6 · Cited by 55 · see citing works
Self-citation
Biomedical Implant Capsule Formation
Diegidio, P., Friedman, H. I., Gourdie, R. G., Riley, A. E., Yost, M. J., & Goodwin, R. L. (2014) · Annals of Plastic Surgery · doi:10.1097/sap.0000000000000287 · Cited by 54 · see citing works
Extended Nitric Oxide-Releasing Polyurethanes via S-Nitrosothiol-Modified Mesoporous Silica Nanoparticles
Malone‐Povolny, M. J., & Schoenfisch, M. H. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b19236 · Cited by 54 · see citing works
A novel porous collagen scaffold around an implantable biosensor for improving biocompatibility. II. Long‐term in vitro/in vivo sensitivity characteristics of sensors with NDGA‐ or GA‐crosslinked collagen scaffolds
Ju, Y. M., Yu, B., West, L., Moussy, Y., & Moussy, F. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32400 · Cited by 52 · see citing works
Chronic inflammatory responses to microgel‐based implant coatings
Bridges, A. W., Whitmire, R. E., Singh, N., Templeman, K. L., Babensee, J. E., Lyon, L. A., & Garcı́a, A. J. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32669 · Cited by 51 · see citing works
Porous, Dexamethasone-loaded polyurethane coatings extend performance window of implantable glucose sensors in vivo
Vallejo-Heligon, S. G., Brown, N. L., Reichert, W. M., & Klitzman, B. M. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.10.045 · Cited by 50 · see citing works
Self-citation
Modulation of the foreign body response to implanted sensor models through device-based delivery of the tyrosine kinase inhibitor, masitinib
Avula, M., Rao, A. N., McGill, L. D., Grainger, D. W., & Solzbacher, F. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.08.090 · Cited by 46 · see citing works
Stiffness of Protease Sensitive and Cell Adhesive PEG Hydrogels Promotes Neovascularization In Vivo
Schweller, R. M., Wu, Z. J., Klitzman, B. M., & West, J. L. (2017) · Annals of Biomedical Engineering · doi:10.1007/s10439-017-1822-8 · Cited by 45 · see citing works
Self-citation
A dexamethasone‐loaded PLGA microspheres/collagen scaffold composite for implantable glucose sensors
Ju, Y. M., Yu, B., West, L., Moussy, Y., & Moussy, F. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32512 · Cited by 44 · see citing works
Mitigating the foreign body response through ‘immune-instructive’ biomaterials
Kämmerling, L., Fisher, L. E., Antmen, E., Simsek, G. M., Rostam, H. M., Vrana, N. E., & Ghaemmaghami, A. M. (2021) · Journal of Immunology and Regenerative Medicine · doi:10.1016/j.regen.2021.100040 · Cited by 44 · see citing works
BioMEMS for biosensors and closed-loop drug delivery
Coffel, J., & Nuxoll, E. E. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.01.030 · Cited by 44 · see citing works
Next-generation biomaterials for dental pulp tissue immunomodulation
Dal‐Fabbro, R., Swanson, W. B., Capalbo, L. C., Sasaki, H., & Bottino, M. C. (2023) · Dental Materials · doi:10.1016/j.dental.2023.03.013 · Cited by 43 · see citing works
Host Response to Synthetic Versus Natural Biomaterials
Sarkar, K., Xue, Y., & Sant, S. (2016) · Springer eBooks · doi:10.1007/978-3-319-45433-7_5 · Cited by 42 · see citing works
Design and Fabrication of a High-Performance Electrochemical Glucose Sensor
Vaddiraju, S., Legassey, A., Wang, Y., Qiang, L., Burgess, D. J., Jain, F., & Papadimitrakopoulos, F. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500504 · Cited by 42 · see citing works
A pH-Responsive Molecularly Imprinted Hydrogel for Dexamethasone Release
Wei, P., Song, R., Chen, C., Li, Z., Zhu, Z., & Li, S. (2018) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-018-1039-9 · Cited by 41 · see citing works
A Review of the Development of a Vehicle for Localized and Controlled Drug Delivery for Implantable Biosensors
Bhardwaj, U., Papadimitrakopoulos, F., & Burgess, D. J. (2008) · Journal of Diabetes Science and Technology · doi:10.1177/193229680800200611 · Cited by 41 · see citing works
Glucose Sensor Membranes for Mitigating the Foreign Body Response
Koh, A., Nichols, S. P., & Schoenfisch, M. H. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500505 · Cited by 41 · see citing works
Innate and adaptive immune responses in tissue engineering
Sefton, M. V., Babensee, J. E., & Woodhouse, K. A. (2008) · Seminars in Immunology · doi:10.1016/j.smim.2007.12.008 · Cited by 40 · see citing works
A miniaturized transcutaneous system for continuous glucose monitoring
Croce, R. A., Vaddiraju, S., Kondo, J., Wang, Y., Zuo, L., Zhu, K., ISLAM, S. K., Burgess, D. J., Papadimitrakopoulos, F., & Jain, F. (2012) · Biomedical Microdevices · doi:10.1007/s10544-012-9708-x · Cited by 38 · see citing works
Multi-modal delivery of therapeutics using biomaterial scaffolds
Browne, S., & Pandit, A. S. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb00863d · Cited by 38 · see citing works
Wound healing process and mediators: Implications for modulations for hernia repair and mesh integration.
Sadava, E., Krpata, D., Gao, Y., Rosen, M., & Novitsky, Y. (2014) · Journal of Biomedical Materials Research. Part A · doi:10.1002/jbm.a.34676 · Cited by 34 · see citing works
Characterization of porous, dexamethasone-releasing polyurethane coatings for glucose sensors
Vallejo-Heligon, S. G., Klitzman, B. M., & Reichert, W. M. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.07.019 · Cited by 34 · see citing works
Self-citation
Distributed sensor and actuator networks for closed-loop bioelectronic medicine
Bhave, G., Chen, J., Singer, A. L., Sharma, A., & Robinson, J. T. (2021) · Materials Today · doi:10.1016/j.mattod.2020.12.020 · Cited by 34 · see citing works
A remotely operated drug delivery system with an electrolytic pump and a thermo-responsive valve
Yi, Y., Zaher, A., Yassine, O., Kosel, J., & Foulds, I. G. (2015) · Biomicrofluidics · doi:10.1063/1.4927436 · Cited by 33 · see citing works
Long-Term Accurate Continuous Glucose Biosensors via Extended Nitric Oxide Release
Malone‐Povolny, M. J., Merricks, E. P., Wimsey, L. E., Nichols, T. C., & Schoenfisch, M. H. (2019) · ACS Sensors · doi:10.1021/acssensors.9b01779 · Cited by 31 · see citing works
Monitoring with In Vivo Electrochemical Sensors: Navigating the Complexities of Blood and Tissue Reactivity
Vadgama, P. M. (2020) · Sensors · doi:10.3390/s20113149 · Cited by 33 · see citing works
Toward an Injectable Continuous Osmotic Glucose Sensor
Johannessen, E. A., Krushinitskaya, O., Sokolov, A., Hafliger, P. D., Hoogerwerf, A. C., Hinderling, C., Kautio, K. T., Lenkkeri, J., Strömmer, E., Kondratyev, V., et al. (2010) · Journal of Diabetes Science and Technology · doi:10.1177/193229681000400417 · Cited by 33 · see citing works
Dexamethasone Reduces the Foreign Body Reaction to Intraneural Electrode Implants in the Peripheral Nerve of the Rat
de la Oliva, N., Navarro, X., & del Valle, J. (2018) · The Anatomical Record · doi:10.1002/ar.23920 · Cited by 34 · see citing works
Design Considerations for Silica-Particle-Doped Nitric-Oxide-Releasing Polyurethane Glucose Biosensor Membranes
Soto, R. J., Schofield, J. B., Walter, S. E., Malone‐Povolny, M. J., & Schoenfisch, M. H. (2016) · ACS Sensors · doi:10.1021/acssensors.6b00623 · Cited by 31 · see citing works
Material Design in Implantable Biosensors toward Future Personalized Diagnostics and Treatments
Ghorbanizamani, F., Moulahoum, H., Guler, E., & Tımur, S. (2023) · Applied Sciences · doi:10.3390/app13074630 · Cited by 29 · see citing works
Microsphere Erosion in Outer Hydrogel Membranes Creating Macroscopic Porosity to Counter Biofouling-Induced Sensor Degradation
Vaddiraju, S., Wang, Y., Qiang, L., Burgess, D. J., & Papadimitrakopoulos, F. (2012) · Analytical Chemistry · doi:10.1021/ac3022423 · Cited by 29 · see citing works
Cell dynamics and metabolism of the foreign body response: characterizing host-biomaterial interactions for next-generation medical implant biocompatibility
Callaghan, N. I., Rempe, C. N., Froom, Z. S. C. S., Medd, K., & Huyer, L. D. (2024) · Materials Advances · doi:10.1039/d4ma00333k · Cited by 28 · see citing works
Impact of CCL2 and CCR2 chemokine/receptor deficiencies on macrophage recruitment and continuous glucose monitoring in vivo
Klueh, U., Czajkowski, C., Ludzinska, I., Qiao, Y., Frailey, J. T., & Kreutzer, D. L. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.06.026 · Cited by 27 · see citing works
Controlled release of dexamethasone from subcutaneously‐implanted biosensors in pigs: Localized anti‐inflammatory benefit without systemic effects
Ward, W. K., Hansen, J. C., Massoud, R. G., Engle, J. M., Takeno, M. M., & Hauch, K. D. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32651 · Cited by 26 · see citing works
IncreasedIn VivoGlucose Recovery via Nitric Oxide Release
Nichols, S. P., Le, N. N., Klitzman, B., & Schoenfisch, M. H. (2011) · Analytical Chemistry · doi:10.1021/ac103070t · Cited by 26 · see citing works
Self-citation
Long-term functionality of transversal intraneural electrodes is improved by dexamethasone treatment
de la Oliva, N., del Valle, J., Delgado-Martinez, I., Mueller, M., Stieglitz, T., & Navarro, X. (2019) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2019.2897256 · Cited by 26 · see citing works
Current advanced therapy cell-based medicinal products for type-1-diabetes treatment
Cañibano-Hernández, A., del Burgo, L. S., Espona‐Noguera, A., Ciriza, J., & Pedraz, J. L. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.03.041 · Cited by 26 · see citing works
Localized delivery of dexamethasone-21-phosphate via microdialysis implants in rat induces M(GC) macrophage polarization and alters CCL2 concentrations
Keeler, G. D., Durdik, J. M., & Stenken, J. A. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.10.022 · Cited by 25 · see citing works
Discovery and Evaluation of a Functional Ternary Polymer Blend for Bone Repair: Translation from a Microarray to a Clinical Model
Khan, F., Smith, J. O., Kanczler, J. M., Tare, R. S., Oreffo, R. O. C., & Bradley, M. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201202710 · Cited by 24 · see citing works
Multicompartment Drug Release System for Dynamic Modulation of Tissue Responses
Morris, A. H., Mahal, R. S., Udell, J., Wu, M., & Kyriakides, T. R. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700370 · Cited by 24 · see citing works
Biomimetic strategies based on viruses and bacteria for the development of immune evasive biomaterials
Novak, M. T., Bryers, J. D., & Reichert, W. M. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2008.11.025 · Cited by 21 · see citing works
Self-citation
Development of a photon induced drug-delivery implant coating
Alenezi, A., Hulander, M., Atefyekta, S., & Andersson, M. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.01.015 · Cited by 18 · see citing works
Enhancing the Sensitivity of Needle-Implantable Electrochemical Glucose Sensors via Surface Rebuilding
Vaddiraju, S., Legassey, A., Qiang, L., Wang, Y., Burgess, D. J., & Papadimitrakopoulos, F. (2013) · Journal of Diabetes Science and Technology · doi:10.1177/193229681300700221 · Cited by 18 · see citing works
Modulation of the Foreign Body Reaction for Implants in the Subcutaneous Space: Microdialysis Probes as Localized Drug Delivery/Sampling Devices
Mou, X., Lennartz, M. R., Loegering, D. J., & Stenken, J. A. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500316 · Cited by 17 · see citing works
Macrophage microRNA-146a is a central regulator of the foreign body response to biomaterial implants
Mahanty, M., Dutta, B., Ou, W., Zhu, X., Bromberg, J. S., He, X., & Rahaman, S. O. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122855 · Cited by 16 · see citing works
In Situ Nitric Oxide Generating Nano‐Bioactive Glass‐Based Coatings and Its Therapeutic Ion Release toward Attenuating Implant‐Associated Fibrosis and Infection
Moses, J. C., Sapkota, A., Wu, Y., Martinez, I., Handa, H., & Brisbois, E. J. (2025) · Small · doi:10.1002/smll.202411984 · Cited by 16 · see citing works
Combination of Nitric Oxide Release and Surface Texture for Mitigating the Foreign Body Response
Malone‐Povolny, M. J., Bradshaw, T. M., Merricks, E. P., Long, C. T., Nichols, T. C., & Schoenfisch, M. H. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00022 · Cited by 16 · see citing works
Is the Response of Continuous Glucose Monitors to Physiological Changes in Blood Glucose Levels Affected by Sensor Life?
Iscoe, K. E., Davey, R. J., & Fournier, P. A. (2011) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2011.0194 · Cited by 15 · see citing works
The role of Toll-like receptor signaling in the macrophage response to implanted materials
McKiel, L. A., Woodhouse, K. A., & Fitzpatrick, L. E. (2019) · MRS Communications · doi:10.1557/mrc.2019.154 · Cited by 14 · see citing works
Covalent incorporation and controlled release of active dexamethasone from injectable polyethylene glycol hydrogels
Bezuidenhout, D., Oosthuysen, A., Davies, N. H., Ahrenstedt, L., Dobner, S., Roberts, P., & Zilla, P. (2012) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34438 · Cited by 14 · see citing works
Microdialysis sampling techniques applied to studies of the foreign body reaction
Sides, C. R., & Stenken, J. A. (2013) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2013.11.002 · Cited by 13 · see citing works
Role of vascular networks in extending glucose sensor function: Impact of angiogenesis and lymphangiogenesis on continuous glucose monitoring in vivo
Klueh, U., Antar, O. S., Qiao, Y., & Kreutzer, D. L. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35031 · Cited by 13 · see citing works
Biological assessments of multifunctional hydrogel-decorated implantable neural cuff electrode for clinical neurology application
Kim, H., Heo, D. N., Lee, Y. J., Lee, S. J., Kang, J. Y., Lee, S. H., Kwon, I. K., & Hee, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-15551-x · Cited by 13 · see citing works
Electrochemical Glucose Biosensors for Diabetes Care
Ocvirk, G., Buck, H., & DuVall, S. H. (2016) · Bioanalytical reviews · doi:10.1007/11663_2016_3 · Cited by 13 · see citing works
Crosslinked basement membrane‐based coatings enhance glucose sensor function and continuous glucose monitoring in vivo
Klueh, U., Ludzinska, I., Czajkowski, C., Qiao, Y., & Kreutzer, D. L. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36206 · Cited by 13 · see citing works
Point-of-Care and Implantable Biosensors in Cancer Research and Diagnosis
Siontorou, C. G., Nikoleli, G., Nikolelis, D. P., Karapetis, S. K., Tzamtzis, N., & Bratakou, S. (2017) · Springer eBooks · doi:10.1007/978-981-10-4726-8_5 · Cited by 12 · see citing works
Extended (10-Day) Real-Time Monitoring by Dexamethasone-Enhanced Microdialysis in the Injured Rat Cortex
Robbins, E. M., Jaquins‐Gerstl, A., Fine, D. F., Leong, C. L., Dixon, C. E., Wagner, A. K., Boutelle, M. G., & Michael, A. C. (2019) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00145 · Cited by 12 · see citing works
Nitric Oxide Release for Enhanced Biocompatibility and Analytical Performance of Implantable Electrochemical Sensors
Zhang, Q., & Meyerhoff, M. E. (2021) · Electroanalysis · doi:10.1002/elan.202100174 · Cited by 11 · see citing works
Innate and Adaptive Immune Responses in Tissue Engineering
Norton, L. W., & Babensee, J. E. (2009) · Springer eBooks · doi:10.1007/978-3-540-77755-7_50 · Cited by 11 · see citing works
Self-citation
First step toward near-infrared continuous glucose monitoring: in vivo evaluation of antibody coupled biomaterials
Gellynck, K., Kodeck, V., Walle, E. V. D., Kersemans, K., Vos, F. D., Declercq, H., Dubruel, P., Vlaminck, L. E. M., & Cornelissen, M. (2014) · Experimental Biology and Medicine · doi:10.1177/1535370214554878 · Cited by 11 · see citing works
Biomaterial Integration in the Joint: Pathological Considerations, Immunomodulation, and the Extracellular Matrix
von Mentzer, U., Corciulo, C., & Stubelius, A. (2022) · Macromolecular Bioscience · doi:10.1002/mabi.202200037 · Cited by 10 · see citing works
Hydrogels in Biosensing Applications
Topuz, F., Buenger, D., Tanaka, D., & Gröll, J. (2011) · Comprehensive Biomaterials · doi:10.1016/b978-0-08-055294-1.00119-7 · Cited by 10 · see citing works

In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings
Norton, L. W., Tegnell, E., Toporek, S. S., & Reichert, W. M. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.069 · Cited by 104 · see citing works
Self-citation
Multiple tissue response modifiers to promote angiogenesis and prevent the foreign body reaction around subcutaneous implants
Kastellorizios, M., Papadimitrakopoulos, F., & Burgess, D. J. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.07.021 · Cited by 55 · see citing works
A Review of the Development of a Vehicle for Localized and Controlled Drug Delivery for Implantable Biosensors
Bhardwaj, U., Papadimitrakopoulos, F., & Burgess, D. J. (2008) · Journal of Diabetes Science and Technology · doi:10.1177/193229680800200611 · Cited by 41 · see citing works
Concurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesis
Patil, S. D., Papadmitrakopoulos, F., & Burgess, D. J. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.10.013 · Cited by 230 · see citing works
Incorporating dexamethasone release in hydrogel coated microdialysis probes
Norton, L. W., Wisniewski, N., Klíma, K., & Reichert, W. M. (2003) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2002.1136919
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Authors: Norton, L. W., Koschwanez, H. E., Wisniewski, N. A., Klitzman, B., & Reichert, W. M.
Affiliations: Duke University (US)
Corresponding author: Reichert, W.M.
ORCID: Wisniewski, N.A.
Klitzman, B.
Reichert, W.M.
Venue: Journal of Biomedical Materials Research Part A
Publisher: Wiley
Published: 2007-01-18
Volume: 81A
Issue: 4
Pages: 858-869
ISSN: 1549-3296 (ISSN-L)
1552-4965
DOI: 10.1002/jbm.a.31088
PMC: PMC4070388
OpenAlex: W2104634040
Cited by: 128
References: 57
Citations by year: 2026: 1 · 2025: 2 · 2024: 5 · 2023: 4 · 2022: 1 · 2021: 5 · 2020: 4 · 2019: 11 · 2018: 7 · 2017: 7 · 2016: 7 · 2015: 7 · 2014: 8 · 2013: 12 · 2012: 7
FWCI: 5.22
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of Biomedical Materials Research Part A (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of General Medical Sciences (T32GM008555)
National Institute of Diabetes and Digestive and Kidney Diseases (DK54932, R01DK054932, R56DK054932)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
Keywords: vascular endothelial growth factor, dexamethasone, implantable glucose sensor, foreign body reaction, inflammation, angiogenesis, antifouling coatings, polyethylene glycol, 2-hydroxyethyl methacrylate, microdialysis
MeSH terms: Animals, Biological Transport, Blood Vessel Prosthesis, Dexamethasone, Foreign-Body Reaction, Glucose, Inflammation, Male, Polymers, Skin, Sulfones, Rats, Sprague-Dawley, Microdialysis, Neovascularization, Physiologic, Hydrogel, Polyethylene Glycol Dimethacrylate, Vascular Endothelial Growth Factor A, Rats

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Vascular endothelial growth factor and dexamethasone release from nonfouling sensor coatings affect the foreign body response

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