The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Mouchiroud, Laurent, Houtkooper, Riekelt H., Moullan, Norman, Katsyuba, Elena, Ryu, Dongryeol, Cantó, Carles, Mottis, Adrienne, Jo, Young-Suk +4 more·2013·Cell
DOI 10.1016/j.cell.2013.06.016

Cited by (120)

Items 101–120 of 120

  1. Toward understanding genomic instability, mitochondrial dysfunction and aging
    Fakouri, Nima B., Hou, Yujun, Demarest, Tyler G., Christiansen, Louise S., Okur, Mustafa N., Mohanty, Joy G., Croteau, Deborah L., Bohr, Vilhelm A. · 2019 · The FEBS Journal
  2. BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities
    Yaku, Keisuke, Palikhe, Sailesh, Izumi, Hironori, Yoshida, Tomoyuki, Hikosaka, Keisuke, Hayat, Faisal, Karim, Mariam, Iqbal, Tooba, Nitta, Yasuhito, Sato, Atsushi et al. · 2021 · Nature Communications
  3. Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson’s disease
    Lehmann, S, Costa, A C, Celardo, I, Loh, S H Y, Martins, L M · 2016 · Cell Death & Disease
  4. Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet
    Shi, Wenbiao, Hegeman, Maria A., van Dartel, Dorien A.M., Tang, Jing, Suarez, Manuel, Swarts, Hans, van der Hee, Bart, Arola, Lluis, Keijer, Jaap · 2017 · Molecular Nutrition & Food Research
  5. Novel Insights into the Anti-Aging Role of Mitophagy
    2018 · International Review of Cell and Molecular Biology
  6. DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease
    Wang, Heling, Lautrup, Sofie, Caponio, Domenica, Zhang, Jianying, Fang, Evandro · 2021 · International Journal of Molecular Sciences
  7. Sirtuin Inhibition Induces Apoptosis-like Changes in Platelets and Thrombocytopenia
    Kumari, Sharda, Chaurasia, Susheel N., Nayak, Manasa K., Mallick, Ram L., Dash, Debabrata · 2015 · Journal of Biological Chemistry
  8. MicroRNAs, Long Non-Coding RNAs, and Circular RNAs in the Redox Control of Cell Senescence
    Lettieri-Barbato, Daniele, Aquilano, Katia, Punziano, Carolina, Minopoli, Giuseppina, Faraonio, Raffaella · 2022 · Antioxidants
  9. Oxidative Status Predicts Quality in Human Mesenchymal Stem Cells
    Bertolo, Alessandro, Capossela, Simona, Fränkl, Gion, Baur, Martin, Pötzel, Tobias, Stoyanov, Jivko · 2017 · Stem Cell Research & Therapy
  10. Inhibition of NAMPT decreases cell growth and enhances susceptibility to oxidative stress
    Xu, Renhua, Yuan, Zhenwei, Yang, Lijuan, Li, Lele, Li, Dan, Lv, Changjun · 2017 · Oncology Reports
  11. Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
    Rahman, Sajid Ur, Qadeer, Abdul, Wu, Ziyun · 2024 · Aging and disease
  12. SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism
    Varghese, Benluvankar, Chianese, Ugo, Capasso, Lucia, Sian, Veronica, Bontempo, Paola, Conte, Mariarosaria, Benedetti, Rosaria, Altucci, Lucia, Carafa, Vincenzo, Nebbioso, Angela · 2023 · Journal of Translational Medicine
  13. The resurgence of NAD <sup>+</sup>
    Guarente, Leonard · 2016 · Science
  14. Exercise is muscle mitochondrial medicine
    Oliveira, Ashley N., Richards, Brandon J., Slavin, Mikhaela, Hood, David A. · 2021 · Exercise and Sport Sciences Reviews
  15. Xeroderma Pigmentosa Group A (XPA), Nucleotide Excision Repair and Regulation by ATR in Response to Ultraviolet Irradiation
    Musich, Phillip R., Li, Zhengke, Zou, Yue · 2017 · Advances in Experimental Medicine and Biology
  16. Loss of <scp>high‐temperature requirement protein A2</scp> protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia
    Zhou, Haohan, Yuan, Danni, Gao, Weinan, Tian, Jiayi, Sun, Hongyu, Yu, Shuang, Wang, Jincheng, Sun, Liankun · 2020 · IUBMB Life
  17. NAD+ augmentation with nicotinamide riboside improves lymphoid potential of Atm−/− and old mice HSCs
    Zong, Le, Tanaka-Yano, Mayuri, Park, Bongsoo, Yanai, Hagai, Turhan, Ferda T., Croteau, Deborah L., Tian, Jane, Fang, Evandro F., Bohr, Vilhelm A., Beerman, Isabel · 2021 · npj Aging and Mechanisms of Disease
  18. Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice
    Mulvey, Lorna, Sands, William A., Salin, Karine, Carr, Amanda E., Selman, Colin · 2017 · Molecular and Cellular Endocrinology
  19. SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging
    Tran, Khoa A., Gilbert, Michael, Vazquez, Berta N., Ianni, Alessandro, Garcia, Benjamin A., Vaquero, Alejandro, Berger, Shelley L. · 2025 · Molecular Cell
  20. Molecular Perspectives of Mitochondrial Adaptations and Their Role in Cardiac Proteostasis
    Alam, Shafiul, Abdullah, Chowdhury S., Aishwarya, Richa, Morshed, Mahboob, Bhuiyan, Md. Shenuarin · 2020 · Frontiers in Physiology