Epigenetic Mechanisms of Longevity and Aging

Multiplex Genome Engineering Using CRISPR/Cas Systems

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DNA methylation age of human tissues and cell types

Horvath, S. (2013) · Genome Biology · doi:10.1186/gb-2013-14-10-r115 · Cited by 7,075

TOR signaling in growth and metabolism

Wullschleger, S., Loewith, R., & Hall, M. N. (2006) · Cell · doi:10.1016/j.cell.2006.01.016 · Cited by 5,787

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

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Resveratrol improves health and survival of mice on a high-calorie diet

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Genome-wide methylation profiles reveal quantitative views of human aging rates

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Baker, D. J., Wijshake, T., Tchkonia, T., LeBrasseur, N. K., Childs, B. G., van de Sluis, B., Kirkland, J. L., & van Deursen, J. M. (2011) · Nature · doi:10.1038/nature10600 · Cited by 3,670

A C. elegans mutant that lives twice as long as wild type

Kenyon, C., Chang, J., Gensch, E., Rudner, A., & Tabtiang, R. (1993) · Nature · doi:10.1038/366461a0 · Cited by 3,387

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Guo, J., Huang, X., Dou, L., Yan, M., Shen, T., Tang, W., & Li, J. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01251-0 · Cited by 1,976

Epigenetic plasticity and the hallmarks of cancer

Flavahan, W. A., Gaskell, E., & Bernstein, B. E. (2017) · Science · doi:10.1126/science.aal2380 · Cited by 1,340

Idiopathic pulmonary fibrosis

Martinez, F. J., Collard, H. R., Pardo, A., Raghu, G., Richeldi, L., Selman, M., Swigris, J. J., Taniguchi, H., & Wells, A. U. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.74 · Cited by 1,388

Cytoplasmic chromatin triggers inflammation in senescence and cancer

Dou, Z., Ghosh, K., Vizioli, M. G., Zhu, J., Sen, P., Wangensteen, K. J., Simithy, J., Lan, Y., Lin, Y., Zhou, Z., et al. (2017) · Nature · doi:10.1038/nature24050 · Cited by 1,335

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

Alberti, S., & Hyman, A. A. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00326-6 · Cited by 1,165

Mitochondrial dysfunction in cell senescence and aging

Miwa, S., Kashyap, S., Chini, E., & von Zglinicki, T. (2022) · Journal of Clinical Investigation · doi:10.1172/jci158447 · Cited by 1,061

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Ocampo, A., Reddy, P., Martinez-Redondo, P., Platero-Luengo, A., Hatanaka, F., Hishida, T., Li, M., Lam, D., Kurita, M., Beyret, E., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.052 · Cited by 988

Immunosenescence: molecular mechanisms and diseases

Liu, Z., Liang, Q., Ren, Y., Guo, C., Ge, X., Wang, L., Cheng, Q., Luo, P., Zhang, Y., & Han, X. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01451-2 · Cited by 1,082

Unmasking senescence: context-dependent effects of SASP in cancer

Faget, D. V., Ren, Q., & Stewart, S. A. (2019) · Nature Reviews Cancer · doi:10.1038/s41568-019-0156-2 · Cited by 863

Reprogramming to recover youthful epigenetic information and restore vision

Lu, Y., Brommer, B., Tian, X., Krishnan, A., Meer, M., Wang, C., Vera, D. L., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2020) · Nature · doi:10.1038/s41586-020-2975-4 · Cited by 820

Benefits of Metformin in Attenuating the Hallmarks of Aging

Kulkarni, A. S., Gubbi, S., & Barzilai, N. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.04.001 · Cited by 766

Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease

Smith, R. L., Soeters, M. R., Wüst, R. C. I., & Houtkooper, R. H. (2018) · Endocrine Reviews · doi:10.1210/er.2017-00211 · Cited by 787

Loss of epigenetic information as a cause of mammalian aging

Yang, J.-H., Hayano, M., Griffin, P. T., Amorim, J. A., Bonkowski, M. S., Apostolides, J. K., Salfati, E. L., Blanchette, M., Munding, E. M., Bhakta, M., et al. (2023) · Cell · doi:10.1016/j.cell.2022.12.027 · Cited by 643

The roles of DNA, RNA and histone methylation in ageing and cancer

Michalak, E. M., Burr, M. L., Bannister, A. J., & Dawson, M. A. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0143-1 · Cited by 549

Molecular and physiological manifestations and measurement of aging in humans

Khan, S. S., Singer, B. D., & Vaughan, D. E. (2017) · Aging Cell · doi:10.1111/acel.12601 · Cited by 530

The ageing epigenome and its rejuvenation

Zhang, W., Qu, J., Liu, G.-H., & Belmonte, J. C. I. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0204-5 · Cited by 458

The role of retrotransposable elements in ageing and age-associated diseases

Gorbunova, V., Seluanov, A., Mita, P., McKerrow, W., Fenyö, D., Boeke, J. D., Linker, S. B., Gage, F. H., Kreiling, J. A., Petrashen, A. P., et al. (2021) · Nature · doi:10.1038/s41586-021-03542-y · Cited by 446

Evaluating intrinsic and non-intrinsic cancer risk factors

Wu, S., Zhu, W., Thompson, P. A., & Hannun, Y. A. (2018) · Nature Communications · doi:10.1038/s41467-018-05467-z · Cited by 473

Aging Hallmarks and the Role of Oxidative Stress

Maldonado, E., Morales, S., Urbina, F., & Solari, A. (2023) · Antioxidants · doi:10.3390/antiox12030651 · Cited by 491

Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

Zhu, X., Chen, Z., Shen, W., Huang, G., Sedivy, J. M., Wang, H., & Ju, Z. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00646-9 · Cited by 425

Universal DNA methylation age across mammalian tissues

Lu, A. T.-H., Fei, Z., Haghani, A., Robeck, T. R., Zoller, J. A., Li, C. Z., Lowe, R., Yan, Q. J., Zhang, J., Vu, H., et al. (2023) · Nature Aging · doi:10.1038/s43587-023-00462-6 · Cited by 510

Epigenetic Regulation in Neurodegenerative Diseases

Berson, A., Nativio, R., Berger, S. L., & Bonini, N. M. (2018) · Trends in Neurosciences · doi:10.1016/j.tins.2018.05.005 · Cited by 408

Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses

Benayoun, B. A., Pollina, E. A., Singh, P. P., Mahmoudi, S., Harel, I., Casey, K. M., Dulken, B. W., Kundaje, A., & Brunet, A. (2019) · Genome Research · doi:10.1101/gr.240093.118 · Cited by 360

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease

Nativio, R., Lan, Y., Donahue, G., Sidoli, S., Berson, A., Srinivasan, A. R., Shcherbakova, O., Amlie-Wolf, A., Nie, J., Cui, X., et al. (2020) · Nature Genetics · doi:10.1038/s41588-020-0696-0 · Cited by 380

SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species

Tian, X., Firsanov, D., Zhang, Z., Cheng, Y., Luo, L., Tombline, G., Tan, R., Simon, M., Henderson, S., Steffan, J., et al. (2019) · Cell · doi:10.1016/j.cell.2019.03.043 · Cited by 353

Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease

Nativio, R., Donahue, G., Berson, A., Lan, Y., Amlie-Wolf, A., Tuzer, F., Toledo, J. B., Gosai, S. J., Gregory, B. D., Torres, C., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0101-9 · Cited by 363

Guidelines for minimal information on cellular senescence experimentation in vivo

Ogrodnik, M., Carlos Acosta, J., Adams, P. D., d’Adda di Fagagna, F., Baker, D. J., Bishop, C. L., Chandra, T., Collado, M., Gil, J., Gorgoulis, V., et al. (2024) · Cell · doi:10.1016/j.cell.2024.05.059 · Cited by 376

Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial

Fitzgerald, K. N., Hodges, R., Hanes, D., Stack, E., Cheishvili, D., Szyf, M., Henkel, J., Twedt, M. W., Giannopoulou, D., Herdell, J., et al. (2021) · Aging · doi:10.18632/aging.202913 · Cited by 361

Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic

Liu, P., Zhao, H., & Luo, Y. (2017) · Aging and Disease · doi:10.14336/ad.2017.0816 · Cited by 358

Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan

Han, S., Schroeder, E. A., Silva-García, C. G., Hebestreit, K., Mair, W. B., & Brunet, A. (2017) · Nature · doi:10.1038/nature21686 · Cited by 311

The role of histone modifications: from neurodevelopment to neurodiseases

Park, J., Lee, K., Kim, K., & Yi, S.-J. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01078-9 · Cited by 333

Aging and Alzheimer's disease: comparison and associations from molecular to system level

Xia, X., Jiang, Q., McDermott, J., & Han, J. J. (2018) · Aging Cell · doi:10.1111/acel.12802 · Cited by 301

Epigenetic changes during aging and their reprogramming potential

Kane, A. E., & Sinclair, D. A. (2019) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2019.1570075 · Cited by 283

Glycation Damage: A Possible Hub for Major Pathophysiological Disorders and Aging

Fournet, M., Bonté, F., & Desmoulière, A. (2018) · Aging and Disease · doi:10.14336/ad.2017.1121 · Cited by 312

Epigenetic Modifications in Cardiovascular Aging and Diseases

Zhang, W., Song, M., Qu, J. T., & Liu, G. (2018) · Circulation Research · doi:10.1161/circresaha.118.312497 · Cited by 296

Molecular mechanisms of environmental exposures and human disease

Wu, H., Eckhardt, C. M., & Baccarelli, A. (2023) · Nature Reviews Genetics · doi:10.1038/s41576-022-00569-3 · Cited by 296

Regulation of Stem Cell Aging by Metabolism and Epigenetics

Ren, R., Ocampo, A., Liu, G., & Belmonte, J. C. I. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.07.019 · Cited by 286

Aging Hallmarks and Progression and Age-Related Diseases: A Landscape View of Research Advancement

Tenchov, R., Sasso, J. M., Wang, X., & Zhou, Q. A. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00531 · Cited by 276

Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues

Chen, M. B., Yang, A. C., Yousef, H., Lee, D., Chen, W., Schaum, N., Lehallier, B., Quake, S. R., & Wyss-Coray, T. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.03.012 · Cited by 233

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

Gasparoni, G., Bultmann, S., Lutsik, P., Kraus, T. F. J., Sordon, S., Vlcek, J., Dietinger, V., Steinmaurer, M., Haider, M., Mulholland, C. B., et al. (2018) · Epigenetics & Chromatin · doi:10.1186/s13072-018-0211-3 · Cited by 229

Sirtuins, epigenetics and longevity

Wątroba, M., Dudek, I., Skoda, M., Stangret, A., Rzodkiewicz, P., & Szukiewicz, D. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2017.08.001 · Cited by 224

Mechanisms of Short-Chain Fatty Acids Derived from Gut Microbiota in Alzheimer's Disease

Qian, X., Xie, R.-Y., Liu, X., Chen, S., & Tang, H. (2022) · Aging and Disease · doi:10.14336/ad.2021.1215 · Cited by 234

The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: From antioxidant to epigenetic therapy

Griñán-Ferré, C., Bellver-Sanchis, A., Izquierdo, V., Corpas, R., Roig-Soriano, J., Chillón, M., Andres-Lacueva, C., Somogyvári, M., Sőti, C., Sanfeliu, C., et al. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101271 · Cited by 208

Changes in genome architecture and transcriptional dynamics progress independently of sensory experience during post-natal brain development

Tan, L., Ma, W., Wu, H., Zheng, Y., Xing, D., Chen, R., Li, X., Daley, N., Deisseroth, K. A., & Xie, X. S. (2021) · Cell · doi:10.1016/j.cell.2020.12.032 · Cited by 193

Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular Aging

Wu, N. N., Zhang, Y., & Ren, J. T. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/9825061 · Cited by 199

METTL3 counteracts premature aging via m6A-dependent stabilization of MIS12 mRNA

Wu, Z., Shi, Y. X., Lu, M., Song, M., Yu, Z., Wang, J., Wang, S., Ren, J., Yang, Y., Liu, G., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa816 · Cited by 190

Molecular and phenotypic biomarkers of aging

Xia, X., Chen, W., McDermott, J., & Han, J.-D. J. (2017) · F1000Research · doi:10.12688/f1000research.10692.1 · Cited by 188

Advances in Understanding of the Role of Lipid Metabolism in Aging

Chung, K. W. (2021) · Cells · doi:10.3390/cells10040880 · Cited by 191

Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan

Bradshaw, P. C. (2021) · Antioxidants · doi:10.3390/antiox10040572 · Cited by 189

Hepatic stellate cell senescence in liver fibrosis: Characteristics, mechanisms and perspectives

Zhang, M., Salas, S. S., Damba, T., Borghesan, M., Demaria, M., & Moshage, H. J. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111572 · Cited by 192

Hallmarks of the aging T‐cell system

Zhang, H., Weyand, C. M., & Goronzy, J. J. (2021) · FEBS Journal · doi:10.1111/febs.15770 · Cited by 181

Antioxidative nanomaterials and biomedical applications

Liu, Y., & Shi, J. (2019) · Nano Today · doi:10.1016/j.nantod.2019.05.008 · Cited by 174

Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence

Gude, N. A., Broughton, K. M., Firouzi, F., & Sussman, M. A. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0061-5 · Cited by 172

DNA methylation predicts age and provides insight into exceptional longevity of bats

Wilkinson, G. S., Adams, D. M., Haghani, A., Lu, A. T.-H., Zoller, J. A., Breeze, C. E., Arnold, B. D., Ball, H. C., Carter, G. G., Cooper, L. N., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21900-2 · Cited by 175

Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

Al‐Azab, M., Safi, M., Idiiatullina, E., Al‐Shaebi, F., & Zaky, M. Y. (2022) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-022-00366-0 · Cited by 178

BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy

Meyer, D. H., & Schumacher, B. (2021) · Aging Cell · doi:10.1111/acel.13320 · Cited by 165

Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence

Sen, P., Lan, Y., Li, C. Y., Sidoli, S., Donahue, G., Dou, Z., Frederick, B., Chen, Q., Luense, L. J., Garcia, B. A., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.01.021 · Cited by 164

Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging

Deng, P., Yuan, Q., Cheng, Y., Li, J., Liu, Z., Liu, Y., Li, Y., Su, T., Wang, J., Salvo, M. E., et al. (2021) · Cell stem cell · doi:10.1016/j.stem.2021.01.010 · Cited by 165

Epigenetics, DNA damage, and aging

Soto-Palma, C., Niedernhofer, L. J., Faulk, C. D., & Dong, X. (2022) · Journal of Clinical Investigation · doi:10.1172/jci158446 · Cited by 160

WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

Li, G., Ma, L., He, S., Luo, R., Wang, B., Zhang, W., Song, Y., Liao, Z., Ke, W., Xiang, Q., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28990-6 · Cited by 156

Metabolic programs tailor T cell immunity in viral infection, cancer, and aging

Møller, S. H., Hsueh, P., Yu, Y.-R., Zhang, L., & Ho, P. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.02.003 · Cited by 154

Heterochromatin: an epigenetic point of view in aging

Lee, J., Kim, E. W., Croteau, D. L., & Bohr, V. A. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-00497-4 · Cited by 164

Fruit development and epigenetic modifications

Tang, D., Gallusci, P., & Lang, Z. (2020) · New Phytologist · doi:10.1111/nph.16724 · Cited by 148

Linking Lipid Metabolism to Chromatin Regulation in Aging

Papsdorf, K., & Brunet, A. (2018) · Trends in Cell Biology · doi:10.1016/j.tcb.2018.09.004 · Cited by 155

Cellular proteostasis decline in human senescence

Sabath, N., Levy‐Adam, F., Younis, A., Rozales, K., Meller, A., Hadar, S., Soueid‐Baumgarten, S., & Shalgi, R. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2018138117 · Cited by 153

Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders

Delgado‐Morales, R., Agís‐Balboa, R. C., Esteller, M., & Berdasco, M. (2017) · Clinical Epigenetics · doi:10.1186/s13148-017-0365-z · Cited by 147

Epigenetic Regulation of Skin Cells in Natural Aging and Premature Aging Diseases

Orioli, D., & Dellambra, E. (2018) · Cells · doi:10.3390/cells7120268 · Cited by 150

Dynamic DNA methylation during aging: A "prophet" of age-related outcomes

Xiao, F.-H., Wang, H.-T., & Kong, Q.-P. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00107 · Cited by 140

Vitamin D deficiency accelerates ageing and age‐related diseases: a novel hypothesis

Berridge, M. J. (2017) · The Journal of Physiology · doi:10.1113/jp274887 · Cited by 145

Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development

Ashapkin, V. V., Suvorov, A., Pilsner, J. R., Krawetz, S. A., & Sergeyev, O. (2022) · Human Reproduction Update · doi:10.1093/humupd/dmac033 · Cited by 149

Genome-wide RNA polymerase stalling shapes the transcriptome during aging

Gyenis, Á., Chang, J., Demmers, J. J. P. G., Bruens, S. T., Barnhoorn, S., Brandt, R. M. C., Baar, M. P., Rašeta, M., Derks, K., Hoeijmakers, J. H. J., et al. (2023) · Nature Genetics · doi:10.1038/s41588-022-01279-6 · Cited by 144

The interaction between ageing and Alzheimer's disease: insights from the hallmarks of ageing

Liu, Y., Tan, Y., Zhang, Z., Yi, M., Zhu, L., & Peng, W. (2024) · Translational Neurodegeneration · doi:10.1186/s40035-024-00397-x · Cited by 156

Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila

Ma, Z., Wang, H., Cai, Y. A., Wang, H., Niu, K., Wu, X., Ma, H., Yang, Y., Tong, W., Liu, F., et al. (2018) · eLife · doi:10.7554/elife.35368 · Cited by 135

Universal DNA methylation age across mammalian tissuesPreprint

Lu, A. T., Fei, Z., Haghani, A., Robeck, T. R., Zoller, J. A., Li, C., Lowe, R., Yan, Q. J., Zhang, J., Vu, H., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.18.426733 · Cited by 139

Putting the brakes on the cell cycle: mechanisms of cellular growth arrest

Pack, L. R., Daigh, L. H., & Meyer, T. (2019) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2019.05.005 · Cited by 139

New Insights into the Role of Histone Changes in Aging

Yi, S.-J., & Kim, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218241 · Cited by 134

Advances in RNA cytosine-5 methylation: detection, regulatory mechanisms, biological functions and links to cancer

Xue, C., Zhao, Y., & Li, L. (2020) · Biomarker Research · doi:10.1186/s40364-020-00225-0 · Cited by 130

Self-defense of macrophages against oxidative injury: Fighting for their own survival

Virág, L., Jaén, R. I., Regdon, Z., Boscá, L., & Prieto, P. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101261 · Cited by 121

A homeostatic Arid1a-dependent permissive chromatin state licenses hepatocyte responsiveness to liver-injury-associated YAP signaling

Li, W., Yang, L., He, Q., Hu, C., Zhu, L., Ma, X., Ma, X., Bao, S., Li, L., Chen, Y., et al. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.06.008 · Cited by 124

The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review

Capurso, C. A., Bellanti, F., Buglio, A. L., & Vendemiale, G. (2019) · Nutrients · doi:10.3390/nu12010035 · Cited by 124

In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice.

Rodríguez-Matellán, A., Alcazar, N., Hernández, F., Serrano, M., & Ávila, J. (2020) · Stem Cell Reports · doi:10.1016/j.stemcr.2020.09.010 · Cited by 116

Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence

Wu, Y., Tang, L., Huang, H., Yu, Q., Hu, B., Wang, G., Ge, F., Yin, T., Li, S., & Yu, X. (2023) · Nature Communications · doi:10.1038/s41467-023-37094-8 · Cited by 120

Epigenetic Mechanisms of Aging and Aging-Associated Diseases

la Torre, A., Vecchio, F. L., & Greco, A. (2023) · Cells · doi:10.3390/cells12081163 · Cited by 129

Consensus Paper: Cerebellum and Ageing

Arleo, A., Bareš, M., Bernard, J. A., Bogoian, H. R., Bruchhage, M. M. K., Bryant, P., Carlson, E. S., Chan, C. C. H., Chen, L., Chung, C., et al. (2023) · The Cerebellum · doi:10.1007/s12311-023-01577-7 · Cited by 129

The role of epigenetics in renal ageing

Shiels, P. G., McGuinness, D., Eriksson, M., Kooman, J. P., & Stenvinkel, P. (2017) · Nature Reviews Nephrology · doi:10.1038/nrneph.2017.78 · Cited by 114

Two conserved epigenetic regulators prevent healthy ageing

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