Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J., Rohde, Luis A., Zai, Clement C., Agerbo, Esben, Arranz, M.J., Asherson, Philip, Bækvad-Hansen, Marie, Baldursson, Gísli, Bellgrove, Mark, Belliveau, Richard A., Buitelaar, Jan, Burton, Christie L., Bybjerg-Grauholm, Jonas, Casas, Miquel, Cerrato, Felecia, Chambert, Kimberly, Churchhouse, Claire, Cormand, Bru, Crosbie, Jennifer, Dalsgaard, Søren, Demontis, Ditte, Doyle, Alysa E., Dumont, Ashley, Elia, Josephine, Grove, Jakob, Gudmundsson, Olafur O., Haavik, Jan, Hakonarson, Hakon, Hansen, Christine S., Hartman, Catharina A., Hawi, Ziarih, Hervás, Amaia, Hougaard, David M., Howrigan, Daniel P., Huang, Hailiang, Kuntsi, Jonna, Langley, Kate, Lesch, Klaus-Peter, Leung, Patrick W.L., Loo, Sandra K., Martin, Joanna, Martin, Alicia R., McGough, James J., Medland, Sarah E., Moran, Jennifer L., Mors, Ole, Mortensen, Preben B., Oades, Robert D., Palmer, Duncan S., Pedersen, Carsten B., Pedersen, Marianne G., Peters, Triinu, Poterba, Timothy, Poulsen, Jesper B., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Ribasés, Marta, Rothenberger, Aribert, Rovira, Paula, Sánchez-Mora, Cristina, Satterstrom, F. Kyle, Schachar, Russell, Artigas, Maria Soler, Steinberg, Stacy, Stefansson, Hreinn, Turley, Patrick, Walters, G. Bragi, Werge, Thomas, Zayats, Tetyana, Arking, Dan E., Bettella, Francesco, Buxbaum, Joseph D., Christensen, Jane H., Collins, Ryan L., Coon, Hilary, De Rubeis, Silvia, Delorme, Richard, Grice, Dorothy E., Hansen, Thomas F., Holmans, Peter A., Hope, Sigrun, Hultman, Christina M., Klei, Lambertus, Ladd-Acosta, Christine, Magnusson, Pall, Nærland, Terje, Nyegaard, Mette, Pinto, Dalila, Qvist, Per, Rehnström, Karola, Reichenberg, Abraham, Reichert, Jennifer, Roeder, Kathryn, Rouleau, Guy A., Saemundsen, Evald, Sanders, Stephan J., Sandin, Sven, St Pourcain, Beate, Stefansson, Kari, Sutcliffe, James S., Talkowski, Michael E., Weiss, Lauren A., Willsey, A. Jeremy, Agartz, Ingrid, Akil, Huda, Albani, Diego, Alda, Martin, Als, Thomas D., Anjorin, Adebayo, Backlund, Lena, Bass, Nicholas, Bauer, Michael, Baune, Bernhard T., Bellivier, Frank, Bergen, Sarah E., Berrettini, Wade H., Biernacka, Joanna M., Blackwood, Douglas H.R., Bøen, Erlend, Budde, Monika, Bunney, William, Burmeister, Margit, Byerley, William, Byrne, Enda M., Cichon, Sven, Clarke, Toni-Kim, Coleman, Jonathan R.I., Craddock, Nicholas, Curtis, David, Czerski, Piotr M., Dale, Anders M., Dalkner, Nina, Dannlowski, Udo, Degenhardt, Franziska, Di Florio, Arianna, Elvsåshagen, Torbjørn, Etain, Bruno, Fischer, Sascha B., Forstner, Andreas J., Forty, Liz, Frank, Josef, Frye, Mark, Fullerton, Janice M., Gade, Katrin, Gaspar, Héléna A., Gershon, Elliot S., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Gordon-Smith, Katherine, Green, Melissa J., Greenwood, Tiffany A., Grigoroiu-Serbanescu, Maria, Guzman-Parra, José, Hauser, Joanna, Hautzinger, Martin, Heilbronner, Urs, Herms, Stefan, Hoffmann, Per, Holland, Dominic, Jamain, Stéphane, Jones, Ian, Jones, Lisa A., Kandaswamy, Radhika, Kelsoe, John R., Kennedy, James L., Joachim, Oedegaard Ketil, Kittel-Schneider, Sarah, Kogevinas, Manolis, Koller, Anna C., Lavebratt, Catharina, Lewis, Cathryn M., Li, Qingqin S., Lissowska, Jolanta, Loohuis, Loes M.O., Lucae, Susanne, Maaser, Anna, Malt, Ulrik F., Martin, Nicholas G., Martinsson, Lina, McElroy, Susan L., McMahon, Francis J., McQuillin, Andrew, Melle, Ingrid, Metspalu, Andres, Millischer, Vincent, Mitchell, Philip B., Montgomery, Grant W., Morken, Gunnar, Morris, Derek W., Müller-Myhsok, Bertram, Mullins, Niamh, Myers, Richard M., Nievergelt, Caroline M., Nordentoft, Merete, Adolfsson, Annelie Nordin, Nöthen, Markus M., Ophoff, Roel A., Owen, Michael J., Paciga, Sara A., Pato, Carlos N., Pato, Michele T., Perlis, Roy H., Perry, Amy, Potash, James B., Reinbold, Céline S., Rietschel, Marcella, Rivera, Margarita, Roberson, Mary, Schalling, Martin, Schofield, Peter R., Schulze, Thomas G., Scott, Laura J., Serretti, Alessandro, Sigurdsson, Engilbert, Smeland, Olav B., Stordal, Eystein, Streit, Fabian, Strohmaier, Jana, Thorgeirsson, Thorgeir E., Treutlein, Jens, Turecki, Gustavo, Vaaler, Arne E., Vieta, Eduard, Vincent, John B., Wang, Yunpeng, Witt, Stephanie H., Zandi, Peter, Adan, Roger A.H., Alfredsson, Lars, Ando, Tetsuya, Aschauer, Harald, Baker, Jessica H., Bencko, Vladimir, Bergen, Andrew W., Birgegård, Andreas, Perica, Vesna Boraska, Brandt, Harry, Burghardt, Roland, Carlberg, Laura, Cassina, Matteo, Clementi, Maurizio, Courtet, Philippe, Crawford, Steven, Crow, Scott, Crowley, James J., Danner, Unna N., Davis, Oliver S.P., Degortes, Daniela, DeSocio, Janiece E., Dick, Danielle M., Dina, Christian, Docampo, Elisa, Egberts, Karin, Ehrlich, Stefan, Espeseth, Thomas, Fernández-Aranda, Fernando, Fichter, Manfred M., Foretova, Lenka, Forzan, Monica, Gambaro, Giovanni, Giegling, Ina, Gonidakis, Fragiskos, Gorwood, Philip, Mayora, Monica Gratacos, Guo, Yiran, Halmi, Katherine A., Hatzikotoulas, Konstantinos, Hebebrand, Johannes, Helder, Sietske G., Herpertz-Dahlmann, Beate, Herzog, Wolfgang, Hinney, Anke, Imgart, Hartmut, Jiménez-Murcia, Susana, Johnson, Craig, Jordan, Jennifer, Julià, Antonio, Kaminská, Deborah, Karhunen, Leila, Karwautz, Andreas, Kas, Martien J.H., Kaye, Walter H., Kennedy, Martin A., Kim, Youl-Ri, Klareskog, Lars, Klump, Kelly L., Knudsen, Gun Peggy S., Landén, Mikael, Le Hellard, Stephanie, Levitan, Robert D., Li, Dong, Lichtenstein, Paul, Maj, Mario, Marsal, Sara, McDevitt, Sara, Mitchell, James, Monteleone, Palmiero, Monteleone, Alessio Maria, Munn-Chernoff, Melissa A., Nacmias, Benedetta, Navratilova, Marie, O’Toole, Julie K., Padyukov, Leonid, Pantel, Jacques, Papezova, Hana, Rabionet, Raquel, Raevuori, Anu, Ramoz, Nicolas, Reichborn-Kjennerud, Ted, Ricca, Valdo, Roberts, Marion, Rujescu, Dan, Rybakowski, Filip, Scherag, André, Schmidt, Ulrike, Seitz, Jochen, Slachtova, Lenka, Slof-Op‘t Landt, Margarita C.T., Slopien, Agnieszka, Sorbi, Sandro, Southam, Lorraine, Strober, Michael, Tortorella, Alfonso, Tozzi, Federica, Treasure, Janet, Tziouvas, Konstantinos, van Elburg, Annemarie A., Wade, Tracey D., Wagner, Gudrun, Walton, Esther, Watson, Hunna J., Wichmann, H-Erich, Woodside, D. Blake, Zeggini, Eleftheria, Zerwas, Stephanie, Zipfel, Stephan, Adams, Mark J., Andlauer, Till F.M., Berger, Klaus, Binder, Elisabeth B., Boomsma, Dorret I., Castelao, Enrique, Colodro-Conde, Lucía, Direk, Nese, Docherty, Anna R., Domenici, Enrico, Domschke, Katharina, Dunn, Erin C., Foo, Jerome C., de. Geus, E.J.C., Grabe, Hans J., Hamilton, Steven P., Horn, Carsten, Hottenga, Jouke-Jan, Howard, David, Ising, Marcus, Kloiber, Stefan, Levinson, Douglas F., Lewis, Glyn, Magnusson, Patrik K.E., Mbarek, Hamdi, Middeldorp, Christel M., Mostafavi, Sara, Nyholt, Dale R., Penninx, Brenda WJH., Peterson, Roseann E., Pistis, Giorgio, Porteous, David J., Preisig, Martin, Quiroz, Jorge A., Schaefer, Catherine, Schulte, Eva C., Shi, Jianxin, Smith, Daniel J., Thomson, Pippa A., Tiemeier, Henning, Uher, Rudolf, van der Auwera, Sandra, Weissman, Myrna M., Alexander, Madeline, Begemann, Martin, Bramon, Elvira, Buccola, Nancy G., Cairns, Murray J., Campion, Dominique, Carr, Vaughan J., Cloninger, C. Robert, Cohen, David, Collier, David A., Corvin, Aiden, DeLisi, Lynn E., Donohoe, Gary, Dudbridge, Frank, Duan, Jubao, Freedman, Robert, Gejman, Pablo V., Golimbet, Vera, Godard, Stephanie, Ehrenreich, Hannelore, Hartmann, Annette M., Henskens, Frans A., Ikeda, Masashi, Iwata, Nakao, Jablensky, Assen V., Joa, Inge, Jönsson, Erik G., Kelly, Brian J., Knight, Jo, Konte, Bettina, Laurent-Levinson, Claudine, Lee, Jimmy, Lencz, Todd, Lerer, Bernard, Loughland, Carmel M., Malhotra, Anil K., Mallet, Jacques, McDonald, Colm, Mitjans, Marina, Mowry, Bryan J., Murphy, Kieran C., Murray, Robin M., O’Neill, F. Anthony, Oh, Sang-Yun, Palotie, Aarno, Pantelis, Christos, Pulver, Ann E., Petryshen, Tracey L., Quested, Digby J., Riley, Brien, Sanders, Alan R., Schall, Ulrich, Schwab, Sibylle G., Scott, Rodney J., Sham, Pak C., Silverman, Jeremy M., Sim, Kang, Steixner, Agnes A., Tooney, Paul A., van Os, Jim, Vawter, Marquis P., Walsh, Dermot, Weiser, Mark, Wildenauer, Dieter B., Williams, Nigel M., Wormley, Brandon K., Zhang, Fuquan, Androutsos, Christos, Arnold, Paul D., Barr, Cathy L., Barta, Csaba, Bey, Katharina, Bienvenu, O. Joseph, Black, Donald W., Brown, Lawrence W., Budman, Cathy, Cath, Danielle, Cheon, Keun-Ah, Ciullo, Valentina, Coffey, Barbara J., Cusi, Daniele, Davis, Lea K., Denys, Damiaan, Depienne, Christel, Dietrich, Andrea, Eapen, Valsamma, Falkai, Peter, Fernandez, Thomas V., Garcia-Delgar, Blanca, Geller, Daniel A., Gilbert, Donald L., Grados, Marco A., Greenberg, Erica, Grünblatt, Edna, Hagstrøm, Julie, Hanna, Gregory L., Hartmann, Andreas, Hedderly, Tammy, Heiman, Gary A., Heyman, Isobel, Hong, Hyun Ju, Huang, Alden, Huyser, Chaim, Ibanez-Gomez, Laura, Khramtsova, Ekaterina A., Kim, Young Key, Kim, Young-Shin, King, Robert A., Koh, Yun-Joo, Konstantinidis, Anastasios, Kook, Sodahm, Kuperman, Samuel, Leventhal, Bennett L., Lochner, Christine, Ludolph, Andrea G., Madruga-Garrido, Marcos, Malaty, Irene, Maras, Athanasios, McCracken, James T., Meijer, Inge A., Mir, Pablo, Morer, Astrid, Müller-Vahl, Kirsten R., Münchau, Alexander, Murphy, Tara L., Naarden, Allan, Nagy, Peter, Nestadt, Gerald, Nestadt, Paul S., Nicolini, Humberto, Nurmi, Erika L., Okun, Michael S., Paschou, Peristera, Piras, Fabrizio, Piras, Federica, Pittenger, Christopher, Plessen, Kerstin J., Richter, Margaret A., Rizzo, Renata, Robertson, Mary, Roessner, Veit, Ruhrmann, Stephan, Samuels, Jack F., Sandor, Paul, Schlögelhofer, Monika, Shin, Eun-Young, Singer, Harvey, Song, Dong-Ho, Song, Jungeun, Spalletta, Gianfranco, Stein, Dan J., Stewart, S Evelyn, Storch, Eric A., Stranger, Barbara, Stuhrmann, Manfred, Tarnok, Zsanett, Tischfield, Jay A., Tübing, Jennifer, Visscher, Frank, Vulink, Nienke, Wagner, Michael, Walitza, Susanne, Wanderer, Sina, Woods, Martin, Worbe, Yulia, Zai, Gwyneth, Zinner, Samuel H., Sullivan, Patrick F., Franke, Barbara, Daly, Mark J., Bulik, Cynthia M., Lewis, Cathryn M., McIntosh, Andrew M., O’Donovan, Michael C., Zheutlin, Amanda, Andreassen, Ole A., Børglum, Anders D., Breen, Gerome, Edenberg, Howard J., Fanous, Ayman H., Faraone, Stephen V., Gelernter, Joel, Mathews, Carol A., Mattheisen, Manuel, Mitchell, Karen S., Neale, Michael C., Nurnberger, John I., Ripke, Stephan, Santangelo, Susan L., Scharf, Jeremiah M., Stein, Murray B., Thornton, Laura M., Walters, James T.R., Wray, Naomi R., Geschwind, Daniel H., Neale, Benjamin M., Kendler, Kenneth S., Smoller, Jordan W.·2019·Cell

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  54. Use of big data and machine learning algorithms to extract possible treatment targets in neurodevelopmental disorders
    Muhammad Ammar Malik, Stephen V. Faraone, Tom Michoel, Jan Haavik · 2023 · Pharmacology & Therapeutics
  55. Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy
    Ellen Verhoef, Jakob Grove, Chin Yang Shapland, Ditte Demontis, Stephen Burgess, Dheeraj Rai, Anders Dupont Børglum, Beaté St Pourcain · 2021 · Nature Communications
  56. Dissection of the Genetic Association between Anorexia Nervosa and Obsessive–Compulsive Disorder at the Network and Cellular Levels
    Weichen Song, Weidi Wang, Shunying Yu, Guan Ning Lin · 2021 · Genes
  57. Psychosocial moderators of polygenic risk for suicidal ideation: Results from a 7-year population-based, prospective cohort study of U.S. veterans
    Peter Jongho Na, Flavio De Angelis, Brandon Nichter, Frank R. Wendt, John Harrison Krystal, Steven Mark Southwick, Daniel F. Levey, Joel E. Gelernter, Renato A Polimanti, Robert H. Pietrzak · 2021 · Molecular Psychiatry
  58. Integrative multi-dimensional characterization of striatal projection neuron heterogeneity in adult brain
    Jenesis D. Gayden, Stéphanie Puig, Chaitanya Srinivasan, BaDoi N. Phan, Ghada Abdelhady, Silas A. Buck, Mackenzie C. Gamble, Hugo A. Tejeda, Yan Dong, Andreas R. Pfenning et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Intergenerational transmission of parental neuroticism to emotional problems in 8‐year‐old children: Genetic and environmental influences
    Helga Ask, Espen Moen Eilertsen, Line Cecilie Gjerde, Laurie J. Hannigan, Kristin Gustavson, Alexandra Havdahl, Rosa Cheesman, Tom A. McAdams, John M. Hettema, Ted Reichborn‐Kjennerud et al. · 2021 · JCPP Advances
  60. Eye Movement Patterns Can Distinguish Schizophrenia From the Major Affective Disorders and Healthy Control Subjects
    David St Clair, Graeme MacLennan, Sara A. Beedie, Eva Nouzová, Helen A. Lemmon, Dan Rujescu, Philip J Benson, Andrew Mark McIntosh, Mintu Nath · 2021 · Schizophrenia Bulletin Open
  61. Co-Occurrence of Tic Disorders and Attention-Deficit/Hyperactivity Disorder—Does It Reflect a Common Neurobiological Background?
    Aribert Rothenberger, Hartmut Heinrich · 2022 · Biomedicines
  62. Genome‐wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
    Børge Holen, Alexey A. Shadrin, Romain Icick, Tahir Tekin Filiz, Guy Hindley, Linn Nilsen Rødevand, Kevin Sean O’Connell, Espen Hagen, Oleksandr Frei, Shahram Bahrami et al. · 2023 · Addiction Biology
  63. Risk Factors, Clinical Features, and Polygenic Risk Scores in Schizophrenia and Schizoaffective Disorder Depressive-Type
    Charlotte A. Dennison, Sophie E. Legge, Leon Hubbard, Amy Joanne Lynham, Stanley Zammit, Peter Holmans, Alastair G. Cardno, Michael John Owen, Michael C. O’Donovan, James Walters · 2021 · Schizophrenia Bulletin
  64. Microglial involvement in autism spectrum disorder: insights from human data and iPSC models
    Susanne Michels, Akash Shivling Mali, Henna Jäntti, Mohammad Rezaie, Tarja Malm · 2025 · Brain Behavior and Immunity
  65. Association Between Parental Anxiety and Depression Level and Psychopathological Symptoms in Offspring With 22q11.2 Deletion Syndrome
    Corrado Sandini, Maude Schneider, Stephan Eliez M. D, Marco Armando · 2020 · Frontiers in Psychiatry
  66. Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs
    Tiit Örd, Daima Örd, Priit Adler, Tõnis Örd · 2023 · PLoS Genetics
  67. Region-specific microRNA alterations in marmosets carrying SLC6A4 polymorphisms are associated with anxiety-like behavior
    Natalia Popa, Dipankar Bachar, Angela Roberts, Andrea M. Santangelo, Eduardo Gascon · 2022 · EBioMedicine
  68. Cross-disorder GWAS meta-analysis of endocannabinoid DNA variations in major depressive disorder, bipolar disorder, attention deficit hyperactivity disorder, autism spectrum disorder, and schizophrenia
    Helena Kyunghee Kim, Vanessa Faria Gonçalves, Muhammad Ishrat Husain, Daniel J. Müller, Benoit H. Mulsant, Gwyneth C. Zai, Stefan M. Kloiber · 2023 · Psychiatry Research
  69. Label-based meta-analysis of functional brain dysconnectivity across mood and psychotic disorders
    Stéphanie Grot, Salima Smine, Stéphane Potvin, Maëliss Darcey, Vilena Pavlov, Sarah Genon, Hien D. Nguyen, Pierre Orban · 2024 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  70. Transdiagnostic findings across major depressive disorder, bipolar disorder and schizophrenia: A qualitative review
    Frederike Stein, Tilo T. J. Kircher · 2025 · Journal of Affective Disorders
  71. Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants
    Rui Chen, Zhihui Yang, Jiewei Liu, Xin Min Cai, Yongxia Huo, Zhijun Zhang, Ming Li, Hong Chang, Xiong‐Jian Luo · 2022 · Genome Medicine
  72. Associated Genetics and Connectomic Circuitry in Schizophrenia and Bipolar Disorder
    Yongbin Wei, Siemon C. de Lange, Jeanne E. Savage, Elleke Tissink, Ting Qi, Jonathan Repple, Marius Gruber, Tilo T. J. Kircher, Udo Dannlowski, Daniëlle Posthuma et al. · 2022 · Biological Psychiatry
  73. An investigation on the alterations in Wnt signaling in ADHD across developmental stages
    Natalie Monet Walter, Cristine Marie Yde Ohki, Michelle Rickli, Lukasz Smigielski, Susanne Walitza, Edna Grünblatt · 2024 · Neuroscience Applied
  74. DNA methylation and general psychopathology in childhood: an epigenome-wide meta-analysis from the PACE consortium
    Jolien Rijlaarsdam, Marta Cosín‐Tomás, Laura Schellhas, Sarina Abrishamcar, Anni Malmberg, Alexander Neumann, Janine F. Felix, Jordi Sunyer, Kristine B. Gützkow, Regina Gražulevičienė et al. · 2022 · Molecular Psychiatry
  75. Hydroxyzine Use in Preschool Children and Its Effect on Neurodevelopment: A Population-Based Longitudinal Study
    Gober, Hans J., Li, Kathy H., Yan, Kevin, Bailey, Anthony J., Carleton, Bruce C. · 2022 · Frontiers in Psychiatry
  76. Bipolar women's antepartum psychotropic exposure and offspring risk of attention-deficit/hyperactivity disorder and autism spectrum disorder
    Ta‐Chuan Yeh, Ya‐Mei Bai, Ju-Wei Hsu, Kai-Ling Huang, Shih‐Jen Tsai, Hsuan‐Te Chu, Chih‐Sung Liang, Mu‐Hong Chen · 2021 · Journal of Affective Disorders
  77. Leveraging pleiotropy for the improved treatment of psychiatric disorders
    Damian J. Woodward, Jackson G. Thorp, Christel Maria Middeldorp, Wọlé Akóṣílè, Eske M. Derks, Zachary F. Gerring · 2024 · Molecular Psychiatry
  78. Shared Genetic Architecture Between Schizophrenia and Anorexia Nervosa: A Cross-trait Genome-Wide Analysis
    Zheng-An Lu, Alexander Ploner, Andreas Birgegård, Roger A.H. Adan, Lars S. Alfredsson, Tetsuya Ando, Ole A. Andreassen, Jessica H. Baker, Andrew W. Bergen, Wade H. Berrettini et al. · 2024 · Schizophrenia Bulletin
  79. The Habenula in the Link Between ADHD and Mood Disorder
    Young‐A Lee, Yukiori Goto · 2021 · Frontiers in Behavioral Neuroscience
  80. Characterizing the polygenic overlaps of bipolar disorder subtypes with schizophrenia and major depressive disorder
    Zongchang Li, David Li, Xiaogang Chen · 2022 · Journal of Affective Disorders
  81. Childhood Obsessive–Compulsive Disorder
    McKenzie Schuyler, DANIEL A. GELLER · 2022 · Psychiatric Clinics of North America
  82. Telencephalon Organoids Derived from an Individual with ADHD Show Altered Neurodevelopment of Early Cortical Layer Structure
    Danmeng Zhang, Noriomi Eguchi, Satoshi Okazaki, Ichiro Sora, Akitoyo Hishimoto · 2023 · Stem Cell Reviews and Reports
  83. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression
    Joanna Martin, Kimiya Asjadi, Leon Hubbard, Kimberley Marie Kendall, Antonio F. Pardiñas, Bradley S. Jermy, Cathryn M. Lewis, Bernhard Theodor Baune, Dorret Irene Boomsma, Steven P. Hamilton et al. · 2021 · PLoS ONE
  84. Integration of Multimodal Data for Deciphering Brain Disorders
    Jingqi Chen, Guiying Dong, Liting Song, Xingzhong Zhao, Jixin Cao, Xiaohui Luo, Jianfeng Feng, Xing‐Ming Zhao · 2021 · Annual Review of Biomedical Data Science
  85. Genetic neurodevelopmental clustering and dyslexia
    Austėja Čiulkinytė, Hayley S. Mountford, Pierre Fontanillas, Stella W. Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg, Jonathan Bowes, Katarzyna Bryc et al. · 2024 · Molecular Psychiatry
  86. Mapping relationships between ADHD genetic liability, stressful life events, and ADHD symptoms in healthy adults
    Ting Li, Barbara Franke, Alejandro Arias Vásquez, Nina Roth Mota · 2020 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  87. The genetic background of the associations between sense of coherence and mental health, self-esteem and personality
    Karri Silventoinen, Eero Vuoksimaa, Salla‐Maarit Volanen, Teemu Palviainen, Richard J. Rose, Sakari Suominen, Jaakko A. Kaprio · 2021 · Social Psychiatry and Psychiatric Epidemiology
  88. Local patterns of genetic sharing between neuropsychiatric and insulin resistance-related conditions
    Giuseppe Fanelli, Barbara Franke, Chiara Fabbri, Josefin Werme, Izel Erdogan, Ward De Witte, Geert Poelmans, I. Hyun Ruisch, Lianne Maria Reus, Veerle van Gils et al. · 2025 · Translational Psychiatry
  89. Understanding the relationship between loneliness, substance use traits and psychiatric disorders: A genetically informed approach
    Ellen Martin, Tabea Schoeler, Jean‐Baptiste Pingault, Wikus Barkhuizen · 2023 · Psychiatry Research
  90. A comprehensive in silico investigation into the nsSNPs of Drd2 gene predicts significant functional consequences in dopamine signaling and pharmacotherapy
    Samia Sultana Lira, Ishtiaque Ahammad · 2021 · Scientific Reports
  91. The Landscape of Shared and Divergent Genetic Influences across 14 Psychiatric Disorders
    Andrew David Grotzinger, Josefin Werme, Wouter J. Peyrot, Oleksandr Frei, Christiaan A. de Leeuw, Lucy K. Bicks, Qiuyu Guo, Michael P. Margolis, Brandon J. Coombes, Anthony J. Batzler et al. · 2025 · medRxiv
  92. The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study
    Isabelle Francesca Foote, Benjamin M. Jacobs, Georgina Mathlin, Cameron James Watson, Phazha LK Bothongo, Sheena Waters, Ruth Dobson, Alastair John Noyce, Kamaldeep Singh Bhui, Ania Korszun et al. · 2022 · Neurobiology of Aging
  93. Machine Learning for Neurodevelopmental Disorders
    Clara A. Moreau, Christine Deruelle, Guillaume Auzias · 2023 · Neuromethods
  94. Polygenic Risk Scores and Twin Concordance for Schizophrenia and Bipolar Disorder
    Jie Song, Joëlle A. Pasman, Viktoria Johansson, Ralf Kuja‐Halkola, Arvid Harder, Robert Karlsson, Yi Lü, Kaarina Kowalec, Nancy L. Pedersen, Tyrone D. Cannon et al. · 2024 · JAMA Psychiatry
  95. Genomic relationships across psychiatric disorders including substance use disorders
    2020
  96. Electronic health records identify timely trends in childhood mental health conditions
    Josephine Elia, KATHLEEN A. PAJER, Raghuram Prasad, Andres Julio Pumariega, Mitchell Maltenfort, Levon Utidjian, Elizabeth A. Shenkman, Kelly J. Kelleher, Suchitra Rao, Peter A. Margolis et al. · 2023 · Child and Adolescent Psychiatry and Mental Health
  97. Transcriptome profiling in adult attention-deficit hyperactivity disorder
    Niall Mortimer, Cristina Sánchez‐Mora, Paula Rovira, Laura Vilar‐Ribó, Vanesa Richarte B, Montse Corrales F, Christian Fadeuilhe, Olga Rivero, Klaus‐Peter Lesch, Miguel Casas et al. · 2020 · European Neuropsychopharmacology
  98. Identification of genetic loci that overlap between schizophrenia and metabolic syndrome
    Honggang Lv, Juan Li, Kai Gao, Lingsi Zeng, Ranran Xue, Xia Liu, Cong Zhou, Weihua Yue, Hao Yu · 2022 · Psychiatry Research
  99. Involvement of Rare Mutations of SCN9A, DPP4, ABCA13, and SYT14 in Schizophrenia and Bipolar Disorder
    2021
  100. The shared genetic risk factors between Tourette syndrome and obsessive-compulsive disorder
    Mohamed Adil Shah Khoodoruth, Foysal Ahammad, Yasser Saeed Khan, Farhan Mohammad · 2023 · Frontiers in Neurology