Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J., Rohde, Luis A., Zai, Clement C., Agerbo, Esben, Arranz, M.J., Asherson, Philip, Bækvad-Hansen, Marie, Baldursson, Gísli, Bellgrove, Mark, Belliveau, Richard A., Buitelaar, Jan, Burton, Christie L., Bybjerg-Grauholm, Jonas, Casas, Miquel, Cerrato, Felecia, Chambert, Kimberly, Churchhouse, Claire, Cormand, Bru, Crosbie, Jennifer, Dalsgaard, Søren, Demontis, Ditte, Doyle, Alysa E., Dumont, Ashley, Elia, Josephine, Grove, Jakob, Gudmundsson, Olafur O., Haavik, Jan, Hakonarson, Hakon, Hansen, Christine S., Hartman, Catharina A., Hawi, Ziarih, Hervás, Amaia, Hougaard, David M., Howrigan, Daniel P., Huang, Hailiang, Kuntsi, Jonna, Langley, Kate, Lesch, Klaus-Peter, Leung, Patrick W.L., Loo, Sandra K., Martin, Joanna, Martin, Alicia R., McGough, James J., Medland, Sarah E., Moran, Jennifer L., Mors, Ole, Mortensen, Preben B., Oades, Robert D., Palmer, Duncan S., Pedersen, Carsten B., Pedersen, Marianne G., Peters, Triinu, Poterba, Timothy, Poulsen, Jesper B., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Ribasés, Marta, Rothenberger, Aribert, Rovira, Paula, Sánchez-Mora, Cristina, Satterstrom, F. Kyle, Schachar, Russell, Artigas, Maria Soler, Steinberg, Stacy, Stefansson, Hreinn, Turley, Patrick, Walters, G. Bragi, Werge, Thomas, Zayats, Tetyana, Arking, Dan E., Bettella, Francesco, Buxbaum, Joseph D., Christensen, Jane H., Collins, Ryan L., Coon, Hilary, De Rubeis, Silvia, Delorme, Richard, Grice, Dorothy E., Hansen, Thomas F., Holmans, Peter A., Hope, Sigrun, Hultman, Christina M., Klei, Lambertus, Ladd-Acosta, Christine, Magnusson, Pall, Nærland, Terje, Nyegaard, Mette, Pinto, Dalila, Qvist, Per, Rehnström, Karola, Reichenberg, Abraham, Reichert, Jennifer, Roeder, Kathryn, Rouleau, Guy A., Saemundsen, Evald, Sanders, Stephan J., Sandin, Sven, St Pourcain, Beate, Stefansson, Kari, Sutcliffe, James S., Talkowski, Michael E., Weiss, Lauren A., Willsey, A. Jeremy, Agartz, Ingrid, Akil, Huda, Albani, Diego, Alda, Martin, Als, Thomas D., Anjorin, Adebayo, Backlund, Lena, Bass, Nicholas, Bauer, Michael, Baune, Bernhard T., Bellivier, Frank, Bergen, Sarah E., Berrettini, Wade H., Biernacka, Joanna M., Blackwood, Douglas H.R., Bøen, Erlend, Budde, Monika, Bunney, William, Burmeister, Margit, Byerley, William, Byrne, Enda M., Cichon, Sven, Clarke, Toni-Kim, Coleman, Jonathan R.I., Craddock, Nicholas, Curtis, David, Czerski, Piotr M., Dale, Anders M., Dalkner, Nina, Dannlowski, Udo, Degenhardt, Franziska, Di Florio, Arianna, Elvsåshagen, Torbjørn, Etain, Bruno, Fischer, Sascha B., Forstner, Andreas J., Forty, Liz, Frank, Josef, Frye, Mark, Fullerton, Janice M., Gade, Katrin, Gaspar, Héléna A., Gershon, Elliot S., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Gordon-Smith, Katherine, Green, Melissa J., Greenwood, Tiffany A., Grigoroiu-Serbanescu, Maria, Guzman-Parra, José, Hauser, Joanna, Hautzinger, Martin, Heilbronner, Urs, Herms, Stefan, Hoffmann, Per, Holland, Dominic, Jamain, Stéphane, Jones, Ian, Jones, Lisa A., Kandaswamy, Radhika, Kelsoe, John R., Kennedy, James L., Joachim, Oedegaard Ketil, Kittel-Schneider, Sarah, Kogevinas, Manolis, Koller, Anna C., Lavebratt, Catharina, Lewis, Cathryn M., Li, Qingqin S., Lissowska, Jolanta, Loohuis, Loes M.O., Lucae, Susanne, Maaser, Anna, Malt, Ulrik F., Martin, Nicholas G., Martinsson, Lina, McElroy, Susan L., McMahon, Francis J., McQuillin, Andrew, Melle, Ingrid, Metspalu, Andres, Millischer, Vincent, Mitchell, Philip B., Montgomery, Grant W., Morken, Gunnar, Morris, Derek W., Müller-Myhsok, Bertram, Mullins, Niamh, Myers, Richard M., Nievergelt, Caroline M., Nordentoft, Merete, Adolfsson, Annelie Nordin, Nöthen, Markus M., Ophoff, Roel A., Owen, Michael J., Paciga, Sara A., Pato, Carlos N., Pato, Michele T., Perlis, Roy H., Perry, Amy, Potash, James B., Reinbold, Céline S., Rietschel, Marcella, Rivera, Margarita, Roberson, Mary, Schalling, Martin, Schofield, Peter R., Schulze, Thomas G., Scott, Laura J., Serretti, Alessandro, Sigurdsson, Engilbert, Smeland, Olav B., Stordal, Eystein, Streit, Fabian, Strohmaier, Jana, Thorgeirsson, Thorgeir E., Treutlein, Jens, Turecki, Gustavo, Vaaler, Arne E., Vieta, Eduard, Vincent, John B., Wang, Yunpeng, Witt, Stephanie H., Zandi, Peter, Adan, Roger A.H., Alfredsson, Lars, Ando, Tetsuya, Aschauer, Harald, Baker, Jessica H., Bencko, Vladimir, Bergen, Andrew W., Birgegård, Andreas, Perica, Vesna Boraska, Brandt, Harry, Burghardt, Roland, Carlberg, Laura, Cassina, Matteo, Clementi, Maurizio, Courtet, Philippe, Crawford, Steven, Crow, Scott, Crowley, James J., Danner, Unna N., Davis, Oliver S.P., Degortes, Daniela, DeSocio, Janiece E., Dick, Danielle M., Dina, Christian, Docampo, Elisa, Egberts, Karin, Ehrlich, Stefan, Espeseth, Thomas, Fernández-Aranda, Fernando, Fichter, Manfred M., Foretova, Lenka, Forzan, Monica, Gambaro, Giovanni, Giegling, Ina, Gonidakis, Fragiskos, Gorwood, Philip, Mayora, Monica Gratacos, Guo, Yiran, Halmi, Katherine A., Hatzikotoulas, Konstantinos, Hebebrand, Johannes, Helder, Sietske G., Herpertz-Dahlmann, Beate, Herzog, Wolfgang, Hinney, Anke, Imgart, Hartmut, Jiménez-Murcia, Susana, Johnson, Craig, Jordan, Jennifer, Julià, Antonio, Kaminská, Deborah, Karhunen, Leila, Karwautz, Andreas, Kas, Martien J.H., Kaye, Walter H., Kennedy, Martin A., Kim, Youl-Ri, Klareskog, Lars, Klump, Kelly L., Knudsen, Gun Peggy S., Landén, Mikael, Le Hellard, Stephanie, Levitan, Robert D., Li, Dong, Lichtenstein, Paul, Maj, Mario, Marsal, Sara, McDevitt, Sara, Mitchell, James, Monteleone, Palmiero, Monteleone, Alessio Maria, Munn-Chernoff, Melissa A., Nacmias, Benedetta, Navratilova, Marie, O’Toole, Julie K., Padyukov, Leonid, Pantel, Jacques, Papezova, Hana, Rabionet, Raquel, Raevuori, Anu, Ramoz, Nicolas, Reichborn-Kjennerud, Ted, Ricca, Valdo, Roberts, Marion, Rujescu, Dan, Rybakowski, Filip, Scherag, André, Schmidt, Ulrike, Seitz, Jochen, Slachtova, Lenka, Slof-Op‘t Landt, Margarita C.T., Slopien, Agnieszka, Sorbi, Sandro, Southam, Lorraine, Strober, Michael, Tortorella, Alfonso, Tozzi, Federica, Treasure, Janet, Tziouvas, Konstantinos, van Elburg, Annemarie A., Wade, Tracey D., Wagner, Gudrun, Walton, Esther, Watson, Hunna J., Wichmann, H-Erich, Woodside, D. Blake, Zeggini, Eleftheria, Zerwas, Stephanie, Zipfel, Stephan, Adams, Mark J., Andlauer, Till F.M., Berger, Klaus, Binder, Elisabeth B., Boomsma, Dorret I., Castelao, Enrique, Colodro-Conde, Lucía, Direk, Nese, Docherty, Anna R., Domenici, Enrico, Domschke, Katharina, Dunn, Erin C., Foo, Jerome C., de. Geus, E.J.C., Grabe, Hans J., Hamilton, Steven P., Horn, Carsten, Hottenga, Jouke-Jan, Howard, David, Ising, Marcus, Kloiber, Stefan, Levinson, Douglas F., Lewis, Glyn, Magnusson, Patrik K.E., Mbarek, Hamdi, Middeldorp, Christel M., Mostafavi, Sara, Nyholt, Dale R., Penninx, Brenda WJH., Peterson, Roseann E., Pistis, Giorgio, Porteous, David J., Preisig, Martin, Quiroz, Jorge A., Schaefer, Catherine, Schulte, Eva C., Shi, Jianxin, Smith, Daniel J., Thomson, Pippa A., Tiemeier, Henning, Uher, Rudolf, van der Auwera, Sandra, Weissman, Myrna M., Alexander, Madeline, Begemann, Martin, Bramon, Elvira, Buccola, Nancy G., Cairns, Murray J., Campion, Dominique, Carr, Vaughan J., Cloninger, C. Robert, Cohen, David, Collier, David A., Corvin, Aiden, DeLisi, Lynn E., Donohoe, Gary, Dudbridge, Frank, Duan, Jubao, Freedman, Robert, Gejman, Pablo V., Golimbet, Vera, Godard, Stephanie, Ehrenreich, Hannelore, Hartmann, Annette M., Henskens, Frans A., Ikeda, Masashi, Iwata, Nakao, Jablensky, Assen V., Joa, Inge, Jönsson, Erik G., Kelly, Brian J., Knight, Jo, Konte, Bettina, Laurent-Levinson, Claudine, Lee, Jimmy, Lencz, Todd, Lerer, Bernard, Loughland, Carmel M., Malhotra, Anil K., Mallet, Jacques, McDonald, Colm, Mitjans, Marina, Mowry, Bryan J., Murphy, Kieran C., Murray, Robin M., O’Neill, F. Anthony, Oh, Sang-Yun, Palotie, Aarno, Pantelis, Christos, Pulver, Ann E., Petryshen, Tracey L., Quested, Digby J., Riley, Brien, Sanders, Alan R., Schall, Ulrich, Schwab, Sibylle G., Scott, Rodney J., Sham, Pak C., Silverman, Jeremy M., Sim, Kang, Steixner, Agnes A., Tooney, Paul A., van Os, Jim, Vawter, Marquis P., Walsh, Dermot, Weiser, Mark, Wildenauer, Dieter B., Williams, Nigel M., Wormley, Brandon K., Zhang, Fuquan, Androutsos, Christos, Arnold, Paul D., Barr, Cathy L., Barta, Csaba, Bey, Katharina, Bienvenu, O. Joseph, Black, Donald W., Brown, Lawrence W., Budman, Cathy, Cath, Danielle, Cheon, Keun-Ah, Ciullo, Valentina, Coffey, Barbara J., Cusi, Daniele, Davis, Lea K., Denys, Damiaan, Depienne, Christel, Dietrich, Andrea, Eapen, Valsamma, Falkai, Peter, Fernandez, Thomas V., Garcia-Delgar, Blanca, Geller, Daniel A., Gilbert, Donald L., Grados, Marco A., Greenberg, Erica, Grünblatt, Edna, Hagstrøm, Julie, Hanna, Gregory L., Hartmann, Andreas, Hedderly, Tammy, Heiman, Gary A., Heyman, Isobel, Hong, Hyun Ju, Huang, Alden, Huyser, Chaim, Ibanez-Gomez, Laura, Khramtsova, Ekaterina A., Kim, Young Key, Kim, Young-Shin, King, Robert A., Koh, Yun-Joo, Konstantinidis, Anastasios, Kook, Sodahm, Kuperman, Samuel, Leventhal, Bennett L., Lochner, Christine, Ludolph, Andrea G., Madruga-Garrido, Marcos, Malaty, Irene, Maras, Athanasios, McCracken, James T., Meijer, Inge A., Mir, Pablo, Morer, Astrid, Müller-Vahl, Kirsten R., Münchau, Alexander, Murphy, Tara L., Naarden, Allan, Nagy, Peter, Nestadt, Gerald, Nestadt, Paul S., Nicolini, Humberto, Nurmi, Erika L., Okun, Michael S., Paschou, Peristera, Piras, Fabrizio, Piras, Federica, Pittenger, Christopher, Plessen, Kerstin J., Richter, Margaret A., Rizzo, Renata, Robertson, Mary, Roessner, Veit, Ruhrmann, Stephan, Samuels, Jack F., Sandor, Paul, Schlögelhofer, Monika, Shin, Eun-Young, Singer, Harvey, Song, Dong-Ho, Song, Jungeun, Spalletta, Gianfranco, Stein, Dan J., Stewart, S Evelyn, Storch, Eric A., Stranger, Barbara, Stuhrmann, Manfred, Tarnok, Zsanett, Tischfield, Jay A., Tübing, Jennifer, Visscher, Frank, Vulink, Nienke, Wagner, Michael, Walitza, Susanne, Wanderer, Sina, Woods, Martin, Worbe, Yulia, Zai, Gwyneth, Zinner, Samuel H., Sullivan, Patrick F., Franke, Barbara, Daly, Mark J., Bulik, Cynthia M., Lewis, Cathryn M., McIntosh, Andrew M., O’Donovan, Michael C., Zheutlin, Amanda, Andreassen, Ole A., Børglum, Anders D., Breen, Gerome, Edenberg, Howard J., Fanous, Ayman H., Faraone, Stephen V., Gelernter, Joel, Mathews, Carol A., Mattheisen, Manuel, Mitchell, Karen S., Neale, Michael C., Nurnberger, John I., Ripke, Stephan, Santangelo, Susan L., Scharf, Jeremiah M., Stein, Murray B., Thornton, Laura M., Walters, James T.R., Wray, Naomi R., Geschwind, Daniel H., Neale, Benjamin M., Kendler, Kenneth S., Smoller, Jordan W.·2019·Cell
DOI 10.1016/j.cell.2019.11.020

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    Jakob Unterholzner, Vincent Millischer, Christoph Wotawa, Akira Sawa, Rupert R. Lanzenberger · 2021 · The International Journal of Neuropsychopharmacology
  53. Running in the FAMILY: understanding and predicting the intergenerational transmission of mental illness
    Lisanne A. E. M. van Houtum, William F.C. Baaré, Christian F. Beckmann, Josefina Castro‐Fornieles, Charlotte A. M. Cecil, Juliane Dittrich, Bjørn Hylsebeck Ebdrup, Jörg Michael Fegert, Alexandra Havdahl, Manon H. J. Hillegers et al. · 2024 · European Child & Adolescent Psychiatry
  54. An Update on the Role of Common Genetic Variation Underlying Substance Use Disorders
    Emma C. Johnson, Yoonhoo Chang, Arpana Agrawal A · 2020 · Current Genetic Medicine Reports
  55. Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits
    2020
  56. Cutting-edge genetics in obsessive-compulsive disorder
    Leonardo Cardoso Saraiva, Carolina Cappi, Helen Blair Simpson, Dan Joseph Stein, Biju Viswanath, Odile A. van den Heuvel, Y.C. Janardhan Reddy, Eurı́pedes Constantino Miguel, Roseli Gedanke Shavitt · 2020 · Faculty Reviews
  57. Genetic factors influencing a neurobiological substrate for psychiatric disorders
    Till F. M. Andlauer, Thomas W. Mühleisen, Felix Hoffstaedter, Alexander Teumer, Katharina Wittfeld, Anja Teuber, Céline S. Reinbold, Dominik Grotegerd, Robin Bülow, Svenja Caspers et al. · 2021 · Translational Psychiatry
  58. Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches
    Ingunn Olea Lund, Laurie J. Hannigan, Helga Ask, Adrian Dahl Askelund, Laura Hegemann, Elizabeth C. Corfield, Robyn E. Wootton, Yasmin Iona Ahmadzadeh, George Davey Smith, Tom A. McAdams et al. · 2025 · BMC Medicine
  59. Circulating miRNAs as Potential Biomarkers for Patient Stratification in Bipolar Disorder: A Combined Review and Data Mining Approach
    Alexandra R. Clausen, Simon Durand, Rasmus L. Petersen, Nicklas Heine Staunstrup, Per Qvist · 2022 · Genes
  60. Disruption of the gene regulatory programme in neurodevelopmental disorders
    Aoife Griffin, Arun Mahesh, Vijay Kumar Tiwari · 2022 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  61. Cortical profiles of numerous psychiatric disorders and normal development share a common pattern
    Zhipeng Cao, Renata Basso Cupertino, Jonatan Ottino‐González, Alistair Murphy, Devarshi Pancholi, Anthony Juliano, Bader Chaarani, Matthew D. Albaugh, Dekang Yuan, Nathan Schwab et al. · 2022 · Molecular Psychiatry
  62. Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning
    Jacob J. Crouse, Joanne Sarah Carpenter, Frank Iorfino, Tian Lin, Nicholas Ho, Enda M. Byrne, Anjali K. Henders, Leanne M. Wallace, Daniel Francis Hermens, Elizabeth M. Scott et al. · 2021 · BJPsych Open
  63. Testing structural models of psychopathology at the genomic level
    2018
  64. DCC gene network in the prefrontal cortex is associated with total brain volume in childhood
    Alice Morgunova, Irina Pokhvisneva, Saara Nolvi, Sonja Entringer, Pathik D. Wadhwa, John H. Gilmore, Martin Andreas Styner, Claudia Buß, Roberto B. Sassi, Geoffrey B. Hall et al. · 2021 · Journal of Psychiatry and Neuroscience
  65. Adulte Aufmerksamkeitsdefizit‑/Hyperaktivitätsstörung und Komorbidität: neue Befunde zu epidemiologischen und genetischen Faktoren
    Sarah Kittel‐Schneider, Andreas Reif · 2020 · Der Nervenarzt
  66. Towards Clinically Relevant Oculomotor Biomarkers in Early Schizophrenia
    Fotios Athanasopoulos, Orionas-Vasilis Saprikis, Myrto Margeli, Christoph Klein, Nikolaos Smyrnis · 2021 · Frontiers in Behavioral Neuroscience
  67. Sleep disturbances in ADHD: investigating the contribution of polygenic liability for ADHD and sleep-related phenotypes
    Katie Swaden Lewis, Joanna Martin, Alice M. Gregory, Richard Anney, Anita Thapar, K. Langley · 2022 · European Child & Adolescent Psychiatry
  68. “Apples and pears are similar, but still different things.” Bipolar disorder and schizophrenia- discrete disorders or just dimensions ?
    Heinz Grunze, Marcelo Cetkovich · 2021 · Journal of Affective Disorders
  69. Multi‐polygenic scores in psychiatry: From disorder specific to transdiagnostic perspectives
    Yingjie Shi, Emma Sprooten, Peter C.R. Mulders, Janna Nonja Vrijsen, Janita Bralten, Ditte Demontis, Anders Dupont Børglum, G. Bragi Walters, Kāri Stefánsson, Philip van Eijndhoven et al. · 2023 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  70. Rare germline variants in individuals diagnosed with schizophrenia within multiplex families
    Shangzhong Li, Lynn E. DeLisi, Stefan I. McDonough · 2021 · Psychiatry Research
  71. Shared and Distinct Functional Effects of Patient-Specific Tbr1 Mutations on Cortical Development
    Marissa Co, Rebecca Barnard, Jennifer N. Jahncke, Sally B. Grindstaff, Lev M. Fedorov, Andrew Adey, Kevin M. Wright, Brian J. O’Roak · 2022 · Journal of Neuroscience
  72. Cohort profile: the Swedish National Quality Register for bipolar disorder(BipoläR)
    Erik Pålsson, Lydia K Melchior, Kristina Lindwall Sundel, Alina Karanti, Erik Joas, Axel Nordenskjöld, Mattias Agestam, Bo Runeson, Mikael Landén · 2022 · BMJ Open
  73. Heritability and polygenic load for comorbid anxiety and depression
    Fara F. Tabrizi, Jörgen Rosén, Hampus Grönvall, Victor Rahimzadeh William-Olsson, Erik Arner, Patrik K. E. Magnusson, Camilla Palm, Henrik Larsson, Alexander Viktorin, Jens Bernhardsson et al. · 2025 · Translational Psychiatry
  74. Relationship between adverse childhood experiences and symptom severity in adult men with Tourette Syndrome
    Kelly G. Yang, Angela Essa, Daisy T Noriega-Makarskyy, Dongmei Yu, Lisa Osiecki, Caitlin A. Gauvin, Cornelia Illmann, Marco Bortolato, Erin C. Dunn, Carol A. Mathews et al. · 2022 · Journal of Psychiatric Research
  75. Dissecting the genetic architecture of suicide attempt and repeated attempts in Korean patients with bipolar disorder using polygenic risk scores
    Lee, Dongbin, Baek, Ji Hyun, Ha, Kyooseob, Cho, Eun-Young, Choi, Yujin, Yang, So-Yung, Kim, Ji Sun, Cho, Yunji, Won, Hong-Hee, Hong, Kyung Sue · 2022 · International Journal of Bipolar Disorders
  76. Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents
    Vanessa Ota, Marcos Leite Santoro, Letícia Spíndola, Pedro Mário Pan, Andressa Simabucuro, Gabriela Xavier, Tamiris Vieira-Fonseca, Évelin Aline Zanardo, Felipe R. C. dos Santos, Julia Schäfer et al. · 2020 · Translational Psychiatry
  77. Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres
    Alexandros Poulopoulos, Patrick W. Davis, Cheryl Brandenburg, Yasuhiro Itoh, Maria José Galazo, Luciano Custo Greig, Andrea J. Romanowski, Bogdan Budnik, Jeffrey D. Macklis · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  78. A genetic screen for Drosophila social isolation mutants and analysis of sex pistol
    Mark Eddison · 2021 · Scientific Reports
  79. Shared and distinct functional connectivity of hippocampal subregions in schizophrenia, bipolar disorder, and major depressive disorder
    Yanzhuo Song, Jingyu Yang, Miao Chang, Yange Wei, Zhiyang Yin, Yue Zhu, Yuning Zhou, Yifang Zhou, Xiaowei Jiang, Feng Wu et al. · 2022 · Frontiers in Psychiatry
  80. Dynamic neuro-immune regulation of psychiatric risk loci in human neurons
    Kayla G. Townsley, Seo Yeon Lee, Sarah E. Williams et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  81. Identifying risk factors involved in the common versus specific liabilities to substance use: A genetically informed approach
    Eleonora Iob, Tabea Schoeler, Charlotte A. M. Cecil, Esther Walton, Andrew McQuillin, Jean‐Baptiste Pingault · 2020 · Addiction Biology
  82. The polygenic basis of relapse after a first episode of schizophrenia.
    À. Segura, Llúcia Prohens, P. Gassó, N. Rodríguez, C. García-Rizo, L. Moreno-Izco, Á. Andreu-Bernabeu, I. Zorrilla, A. Mané, R. Rodríguez-Jiménez et al. · 2023 · European Neuropsychopharmacology
  83. Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk
    Flavio De Angelis, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Aranyak Goswami, Joel E. Gelernter, Renato A Polimanti · 2021 · Translational Psychiatry
  84. Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community
    Cassandra Claire Soo, Jean‐Tristan Brandenburg, Almut Nebel, Stephen M. Tollman, Lisa F. Berkman, Michèle Ramsay, Ananyo Choudhury · 2023 · Communications Biology
  85. Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH)
    Julia Boberg, Viktor Kaldo, David Mataix‐Cols, James J Crowley, Björn Roelstraete, Matthew Halvorsen, Erik Forsell, Nils Hentati Isacsson, Patrick F. Sullivan, Cecilia Svanborg et al. · 2023 · BMJ Open
  86. A three-factor model of common early onset psychiatric disorders: temperament, adversity, and dopamine
    Maisha Iqbal, Sylvia M. L. Cox, Natalia Jaworska, Maria Tippler, Natalie Castellanos Ryan, Sophie Parent, Alain Dagher, Frank Vitaro, Mara R. Brendgen, Michel Boivin et al. · 2021 · Neuropsychopharmacology
  87. Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders
    Manuela R. Kouakou, Darren Cameron, Eilis J. Hannon, Emma Louise Dempster, Jonathan S. Mill, Matthew Hill, Nicholas J. Bray · 2021 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  88. Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank
    Daniël Roelfs, Oleksandr Frei, Dennis van der Meer, Elleke Tissink, Alexey A. Shadrin, Dag Alnæs, Ole A. Andreassen, Lars Tjelta Westlye, Tobias Kaufmann · 2023 · BMC Psychiatry
  89. Attention-mediated genetic influences on psychotic symptomatology in adolescence
    Sarah E. Chang, Dylan Hughes, Jinhan Zhu, Mahnoor Hyat, Sullivan D. Salone, Zachary T. Goodman, Joshua L. Roffman, Nicole R. Karcher, Leanna M. Hernandez, Jennifer K. Forsyth et al. · 2024 · Nature Mental Health
  90. Identifying transdiagnostic biological subtypes across schizophrenia, bipolar disorder, and major depressive disorder based on lipidomics profiles
    Shiwan Tao, Yamin Zhang, Qiang Wang, Chunxia Qiao, Wei Deng, Sugai Liang, Jinxue Wei, Wei Wei, Hua Yu, Xiaojing Li et al. · 2022 · Frontiers in Cell and Developmental Biology
  91. Genomic variants and inferred biological processes in multiplex families with Tourette syndrome
    Jakub Piotr Fichna, Małgorzata Borczyk, Marcin Piechota, Michał Korostyński, Cezary Żekanowski, Piotr Janik · 2023 · Journal of Psychiatry and Neuroscience
  92. A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21
    Claudio Toma A, Alex D. Shaw, Anna Heath, Kerrie D. Pierce, Philip Bowden Mitchell, Peter R. Schofield, Janice M. Fullerton · 2021 · Journal of Psychiatry and Neuroscience
  93. Genetically predicted circulating levels of cytokines and the risk of depression: a bidirectional Mendelian-randomization study
    Meiti Wang, Guixiang Jin, Ying Cheng, Shi‐Yang Guan, Jinxin Zheng, Shun-Xian Zhang · 2023 · Frontiers in Genetics
  94. Individual differences in sensitivity to positive home environment among children “at risk” for attention-deficit/hyperactivity disorder: A review
    Tzlil Einziger, Andrea Berger · 2022 · Frontiers in Psychiatry
  95. Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS
    2020
  96. Heterogeneity-Aware, Multiscale Annotation of Shared and Specific Neurobiological Signatures among Major Neurodevelopmental Disorders
    Yunheng Diao, Yuanyuan Huang, Baoyuan Zhu, Minxin Guo, Wei Wang, Zhaobo Li, Wenhao Li, Heng Zhang, Jing Zhou, Xiaobo Li et al. · 2026 · Research
  97. Neural Correlates of Executive Functioning in Anorexia Nervosa and Obsessive–Compulsive Disorder
    Kai S. Thomas, Rosalind E. Birch, Catherine R. G. Jones, Ross E. Vanderwert · 2022 · Frontiers in Human Neuroscience
  98. A meta-study on transcription factor networks in the suicidal brain
    Brenda Cabrera‐Mendoza, Guillermo de Anda‐Jáuregui, Humberto Nicolini, Cristóbal Fresno · 2021 · Journal of Psychiatric Research
  99. Genes positively regulated by Mef2c in cortical neurons are enriched for common genetic variation associated with IQ and educational attainment
    Laura Fahey, Deema Ali, Gary J Donohoe, Pilib Ó Broin, Derek W. Morris · 2023 · Human Molecular Genetics
  100. Overlapping brain correlates of superior cognition among children at genetic risk for Alzheimer’s disease and/or major depressive disorder
    Raluca Petrican, Amy L. Paine, Valentina Escott‐Price, Katherine H. Shelton · 2023 · Scientific Reports