Motile axonal mitochondria contribute to the variability of presynaptic strength

Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

Thomas, J. A., Buchsbaum, R., Zimniak, A., & Racker, E. (1979) · Biochemistry · doi:10.1021/bi00578a012 · Cited by 2,132 · see citing works

An Expanded Palette of Genetically Encoded Ca 2+ Indicators

Zhao, Y., Araki, S., Wu, J., Teramoto, T., Chang, Y.-F., Nakano, M., Abdelfattah, A. S., Fujiwara, M., Ishihara, T., Nagai, T., et al. (2011) · Science · doi:10.1126/science.1208592 · Cited by 1,265 · see citing works

Variability, compensation and homeostasis in neuron and network function

Marder, E., & Goaillard, J.-M. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1949 · Cited by 1,212 · see citing works

Expanded dynamic range of fluorescent indicators for Ca ²⁺ by circularly permuted yellow fluorescent proteins

Nagai, T., Yamada, S., Tominaga, T., Ichikawa, M., & Miyawaki, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400417101 · Cited by 1,030 · see citing works

Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration

Sheng, Z., & Cai, Q. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3156 · Cited by 906 · see citing works

Synaptic Mitochondria Are Critical for Mobilization of Reserve Pool Vesicles at Drosophila Neuromuscular Junctions

Verstreken, P., Ly, C. V., Venken, K. J. T., Koh, T.-W., Zhou, Y., & Bellen, H. J. (2005) · Neuron · doi:10.1016/j.neuron.2005.06.018 · Cited by 841 · see citing works

Neuronal variability: noise or part of the signal?

Stein, R. B., Gossen, E. R., & Jones, K. E. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1668 · Cited by 658 · see citing works

The probability of transmitter release at a mammalian central synapse

Hessler, N. A., Shirke, A. M., & Malinow, R. (1993) · Nature · doi:10.1038/366569a0 · Cited by 617 · see citing works

Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation

Kang, J.-S., Tian, J.-H., Pan, P.-Y., Zald, P., Li, C., Deng, C., & Sheng, Z.-H. (2008) · Cell · doi:10.1016/j.cell.2007.11.024 · Cited by 598 · see citing works

Heterogeneous Release Properties of Visualized Individual Hippocampal Synapses

Murthy, V. N., B, T. J. S. A., & Stevens, C. F. (1997) · Neuron · doi:10.1016/s0896-6273(00)80301-3 · Cited by 596 · see citing works

A genetically encoded fluorescent reporter of ATP:ADP ratio

Berg, J., Hung, Y. P., & Yellen, G. (2009) · Nature Methods · doi:10.1038/nmeth.1288 · Cited by 481 · see citing works

The probability of neurotransmitter release: variability and feedback control at single synapses

Branco, T., & Staras, K. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2634 · Cited by 445 · see citing works

Mitochondrial Involvement in Post-Tetanic Potentiation of Synaptic Transmission

Tang, Y.-G., & Zucker, R. S. (1997) · Neuron · doi:10.1016/s0896-6273(00)81248-9 · Cited by 441 · see citing works

Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system

Sankaranarayanan, S., & Ryan, T. A. (2000) · Nature Cell Biology · doi:10.1038/35008615 · Cited by 410 · see citing works

Mitochondrial Trafficking to Synapses in Cultured Primary Cortical Neurons

Chang, D. T. W., Honick, A. S., & Reynolds, I. J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1012-06.2006 · Cited by 391 · see citing works

Applicability of the coefficient of variation method for analyzing synaptic plasticity

Faber, D. S., & Korn, H. (1991) · Biophysical Journal · doi:10.1016/s0006-3495(91)82162-2 · Cited by 369 · see citing works

The Neurotransmitter Cycle and Quantal Size

Edwards, R. H. (2007) · Neuron · doi:10.1016/j.neuron.2007.09.001 · Cited by 363 · see citing works

Variability of Neurotransmitter Concentration and Nonsaturation of Postsynaptic AMPA Receptors at Synapses in Hippocampal Cultures and Slices

Liu, G., Choi, S., & Tsien, R. W. (1999) · Neuron · doi:10.1016/s0896-6273(00)81099-5 · Cited by 356 · see citing works

Diversification of synaptic strength: presynaptic elements

Atwood, H. L., & Karunanithi, S. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn876 · Cited by 346 · see citing works

Further observations on hippocampal neurons in dispersed cell culture

Banker, G. A., & Cowan, W. M. (1979) · Journal of Comparative Neurology · doi:10.1002/cne.901870302 · Cited by 285 · see citing works

Impact of Synaptic Unreliability on the Information Transmitted by Spiking Neurons

Zador, A. M. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.3.1219 · Cited by 242 · see citing works

Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

Cai, Q., Lü, L., Tian, J.-H., Zhu, Y.-B., Qiao, H., & Sheng, Z. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.022 · Cited by 241 · see citing works

From the stochasticity of molecular processes to the variability of synaptic transmission

Ribrault, C., Sekimoto, K., & Triller, A. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3025 · Cited by 198 · see citing works

Combining Deconvolution and Noise Analysis for the Estimation of Transmitter Release Rates at the Calyx of Held

Neher, E., & Sakaba, T. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-02-00444.2001 · Cited by 189 · see citing works

Quantal Size and Variation Determined by Vesicle Size in Normal and MutantDrosophilaGlutamatergic Synapses

Karunanithi, S., Marin, L., Wong, K., & Atwood, H. L. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10267.2002 · Cited by 169 · see citing works

Synaptotagmin Has an Essential Function in Synaptic Vesicle Positioning for Synchronous Release in Addition to Its Role as a Calcium Sensor

Young, S., & Neher, E. (2009) · Neuron · doi:10.1016/j.neuron.2009.07.028 · Cited by 134 · see citing works

The Role of Calcium/Calmodulin-Activated Calcineurin in Rapid and Slow Endocytosis at Central Synapses

Sun, T., Wu, X.-S., Xu, J., McNeil, B. D., Pang, Z. P., Yang, W., Bai, L., Qadri, S. M., Molkentin, J. D., Yue, D. T., et al. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1481-10.2010 · Cited by 108 · see citing works

Synaptic Vesicle Exocytosis in Hippocampal Synaptosomes Correlates Directly with Total Mitochondrial Volume

Ivannikov, M. V., Sugimori, M., & Llinás, R. R. (2012) · Journal of Molecular Neuroscience · doi:10.1007/s12031-012-9848-8 · Cited by 106 · see citing works

Roles of ATP in Depletion and Replenishment of the Releasable Pool of Synaptic Vesicles

Heidelberger, R., Sterling, P., & Matthews, G. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.1.98 · Cited by 99 · see citing works

Dynein Light Chain LC8 Regulates Syntaphilin-Mediated Mitochondrial Docking in Axons

Chen, Y., Gerwin, C. M., & Sheng, Z. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1472-09.2009 · Cited by 88 · see citing works

The high variance of AMPA receptor- and NMDA receptor-mediated responses at single hippocampal synapses: Evidence for multiquantal release

Conti, R., & Lisman, J. (2003) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0630290100 · Cited by 77 · see citing works

Mitochondria and release at hippocampal synapses

Waters, J., & Smith, S. J. (2003) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-003-1182-0 · Cited by 22 · see citing works

Brain Glucose Metabolism: Integration of Energetics with Function.

Dienel, G. (2019) · Physiological Reviews · doi:10.1152/physrev.00062.2017 · Cited by 806 · see citing works

Axonal transport: cargo-specific mechanisms of motility and regulation

Maday, S., Twelvetrees, A. E., Moughamian, A. J., & Holzbaur, E. L. F. (2014) · Neuron · doi:10.1016/j.neuron.2014.10.019 · Cited by 683 · see citing works

Mitochondrial signal transduction

Picard, M. A., & Shirihai, O. S. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.10.008 · Cited by 666 · see citing works

Mitochondria at the neuronal presynapse in health and disease

Devine, M. J., & Kittler, J. T. (2018) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.170 · Cited by 615 · see citing works

Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

Monzel, A. S., Enrı́quez, J. A., & Picard, M. A. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00783-1 · Cited by 618 · see citing works

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

Study, T. P. O. B. D., Mertens, J., Wang, Q.-W., Kim, Y., Yu, D. X., Pham, S., Yang, B., Zheng, Y., Diffenderfer, K. E., Zhang, J., et al. (2015) · Nature · doi:10.1038/nature15526 · Cited by 562 · see citing works

An energetic view of stress: Focus on mitochondria

Picard, M. A., McEwen, B. S., Epel, E. S., & Sandi, C. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.01.001 · Cited by 565 · see citing works

The rise of mitochondria in medicine

Picard, M. A., Wallace, D. C., & Burelle, Y. (2016) · Mitochondrion · doi:10.1016/j.mito.2016.07.003 · Cited by 454 · see citing works

Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS

Faust, T. E., Gunner, G., & Schafer, D. P. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00507-y · Cited by 440 · see citing works

Mitochondrial trafficking and anchoring in neurons: New insight and implications

Sheng, Z. (2014) · The Journal of Cell Biology · doi:10.1083/jcb.201312123 · Cited by 409 · see citing works

Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism

Yellen, G. (2018) · Journal of Cell Biology · doi:10.1083/jcb.201803152 · Cited by 371 · see citing works

Mitochondrial function in hypoxic ischemic injury and influence of aging

Ham, P. B., & Raju, R. P. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.06.006 · Cited by 367 · see citing works

Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits

Zhou, B., Yu, P., Lin, M.-Y., Sun, T., Chen, Y., & Sheng, Z. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201605101 · Cited by 321 · see citing works

The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling

Pathak, D., Shields, L. Y., Mendelsohn, B. A., Haddad, D., Lin, W., Gerencser, A. A., Kim, H., Brand, M. D., Edwards, R. H., & Nakamura, K. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.656405 · Cited by 311 · see citing works

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress

Picard, M., McManus, M. J., Gray, J. D., Nasca, C., Moffat, C., Kopinski, P. K., Seifert, E. L., McEwen, B. S., & Wallace, D. C. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1515733112 · Cited by 293 · see citing works

Optogenetic control of organelle transport and positioning

van Bergeijk, P., Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2015) · Nature · doi:10.1038/nature14128 · Cited by 296 · see citing works

Mitochondria Coordinate Sites of Axon Branching through Localized Intra-axonal Protein Synthesis

Spillane, M., Ketschek, A., Merianda, T. T., Twiss, J. L., & Gallo, G. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.11.022 · Cited by 286 · see citing works

Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer’s Disease

Cai, Q., & Tammineni, P. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-160726 · Cited by 274 · see citing works

Energy matters: presynaptic metabolism and the maintenance of synaptic transmission

Li, S., & Sheng, Z. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00535-8 · Cited by 273 · see citing works

Pleiotropic Mitochondria: The Influence of Mitochondria on Neuronal Development and Disease

Rangaraju, V., Lewis, T. L., Hirabayashi, Y., Bergami, M., Motori, E., Cartoni, R., Kwon, S., & Courchet, J. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.1157-19.2019 · Cited by 257 · see citing works

Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance

Raefsky, S. M., & Mattson, M. P. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.11.045 · Cited by 274 · see citing works

Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration

Cheng, X., Huang, N., & Sheng, Z. (2022) · Neuron · doi:10.1016/j.neuron.2022.03.015 · Cited by 253 · see citing works

Mitochondria localize to injured axons to support regeneration

Han, S., Baig, H. S., & Hammarlund, M. (2016) · Neuron · doi:10.1016/j.neuron.2016.11.025 · Cited by 210 · see citing works

Mitochondria impact brain function and cognition

Picard, M. A., & McEwen, B. S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321881111 · Cited by 230 · see citing works

Restoring Cellular Energetics Promotes Axonal Regeneration and Functional Recovery after Spinal Cord Injury

Han, Q., Xie, Y., Ordaz, J. D., Huh, A., Huang, N., Wu, W., Liu, N., Chamberlain, K. A., Sheng, Z., & Xu, X. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.02.002 · Cited by 221 · see citing works

Regulation of mitochondrial transport in neurons

Lin, M.-Y., & Sheng, Z. (2015) · Experimental Cell Research · doi:10.1016/j.yexcr.2015.01.004 · Cited by 223 · see citing works

The Interplay of Axonal Energy Homeostasis and Mitochondrial Trafficking and Anchoring

Sheng, Z.-H. (2017) · Trends in Cell Biology · doi:10.1016/j.tcb.2017.01.005 · Cited by 221 · see citing works

Alterations in Mitochondrial Quality Control in Alzheimer’s Disease

Cai, Q., & Tammineni, P. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00024 · Cited by 215 · see citing works

Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity

Turner, N. L., Macrina, T., Bae, J. A., Yang, R., Wilson, A. M., Schneider-Mizell, C., Lee, K., Lu, R., Wu, J., Bodor, A. L., et al. (2022) · Cell · doi:10.1016/j.cell.2022.01.023 · Cited by 206 · see citing works

A role for tau at the synapse in Alzheimer’s disease pathogenesis

Pooler, A. M., Noble, W., & Hanger, D. P. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.09.018 · Cited by 203 · see citing works

LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons

Kwon, S., Sando, R. C., Lewis, T. L., Hirabayashi, Y., Maximov, A., & Polleux, F. (2016) · PLoS Biology · doi:10.1371/journal.pbio.1002516 · Cited by 201 · see citing works

Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2

Chamberlain, K. A., Huang, N., Xie, Y., Licausi, F., Li, S., Li, Y., & Sheng, Z. (2021) · Neuron · doi:10.1016/j.neuron.2021.08.011 · Cited by 181 · see citing works

The axonal cytoskeleton: from organization to function

Kevenaar, J. T., & Hoogenraad, C. C. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00044 · Cited by 181 · see citing works

Long-Term Plasticity of Neurotransmitter Release: Emerging Mechanisms and Contributions to Brain Function and Disease

Monday, H. R., Younts, T. J., & Castillo, P. E. (2018) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080317-062155 · Cited by 175 · see citing works

The ageing neuromuscular system and sarcopenia: A mitochondrial perspective

Rygiel, K. A., Picard, M., & Turnbull, D. M. (2016) · The Journal of Physiology · doi:10.1113/jp271212 · Cited by 165 · see citing works

Inter and Intracellular mitochondrial trafficking in health and disease

Shanmughapriya, S., Langford, D., & Natarajaseenivasan, K. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101128 · Cited by 171 · see citing works

Targeting mitophagy in neurodegenerative diseases

Antico, O., Thompson, P. W., Hertz, N. T., Muqit, M. M. K., & Parton, L. E. (2025) · Nature Reviews Drug Discovery · doi:10.1038/s41573-024-01105-0 · Cited by 178 · see citing works

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease

Haddad, D., & Nakamura, K. (2015) · FEBS Letters · doi:10.1016/j.febslet.2015.10.021 · Cited by 162 · see citing works

Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease

Cabezas-Opazo, F., Vergara-Pulgar, K., Maria Jose Perez, J., Jara, C., Osorio‐Fuentealba, C., & Quintanilla, R. A. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/509654 · Cited by 148 · see citing works

Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex

Ebrahimi-Fakhari, D., Saffari, A., Wahlster, L., Di Nardo, A., Turner, D., Lewis, T. L., Conrad, C., Rothberg, J. M., Lipton, J. O., Kölker, S., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.09.054 · Cited by 146 · see citing works

The cross-talk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism

Li, S., Xiong, G.-J., Huang, N., & Sheng, Z. (2020) · Nature Metabolism · doi:10.1038/s42255-020-00289-0 · Cited by 144 · see citing works

Astroglial glutamate transporters coordinate excitatory signaling and brain energetics

Robinson, M. B., & Jackson, J. G. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.03.014 · Cited by 144 · see citing works

Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

Smith, H., Bourne, J. N., Cao, G., Chirillo, M. A., Ostroff, L. E., Watson, D. J., & Harris, K. M. (2016) · eLife · doi:10.7554/elife.15275 · Cited by 146 · see citing works

Mechanisms and roles of mitochondrial localisation and dynamics in neuronal function

Seager, R., Lee, L. J., Henley, J. M., & Wilkinson, K. A. (2020) · Neuronal Signaling · doi:10.1042/ns20200008 · Cited by 141 · see citing works

Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder

Robicsek, O., Ene, H. M., Karry, R., Ytzhaki, O., Asor, E., McPhie, D. L., Cohen, B. M., Ben-Yehuda, R., Weiner, I., & Ben‐Shachar, D. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx077 · Cited by 134 · see citing works

Miro1‐dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity

Vaccaro, V., Devine, M. J., Higgs, N., & Kittler, J. T. (2016) · EMBO Reports · doi:10.15252/embr.201642710 · Cited by 131 · see citing works

Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease

Pickett, E. K., Rose, J. L., McCrory, C., McKenzie, C.-A., King, D., Smith, C., Gillingwater, T. H., Henstridge, C. M., & Spires‐Jones, T. L. (2018) · Acta Neuropathologica · doi:10.1007/s00401-018-1903-2 · Cited by 128 · see citing works

Brain energetics during the sleep-wake cycle

DiNuzzo, M., & Nedergaard, M. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.09.010 · Cited by 130 · see citing works

TNF-α regulates miRNA targeting mitochondrial complex-I and induces cell death in dopaminergic cells

Prajapati, P., Sripada, L., Singh, K., Bhatelia, K., Singh, R. K., & Singh, R. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.11.019 · Cited by 123 · see citing works

Re-emphasizing early Alzheimer’s disease pathology starting in select entorhinal neurons, with a special focus on mitophagy

Kobro-Flatmoen, A., Lagartos-Donate, M. J., Aman, Y., Edison, P., Witter, M. P., & Fang, E. F. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101307 · Cited by 112 · see citing works

Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile

Kim, Y., Zheng, X., Ansari, Z., Bunnell, M. C., Herdy, J. R., Traxler, L., Lee, H., Paquola, A. C. M., Blithikioti, C., Ku, M., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.04.105 · Cited by 117 · see citing works

Axon and dendritic trafficking

Maeder, C. I., Shen, K., & Hoogenraad, C. C. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.03.015 · Cited by 116 · see citing works

Mitochondria on the move: Horizontal mitochondrial transfer in disease and health

Dong, L., Rohlena, J., Zobalová, R., Nahácka, Z., Rodriguez, A., Berridge, M. V., & Neužil, J. (2023) · The Journal of Cell Biology · doi:10.1083/jcb.202211044 · Cited by 116 · see citing works

Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites

Cserép, C., Pósfai, B., Schwarcz, A. D., & Dénes, Á. (2018) · eNeuro · doi:10.1523/eneuro.0390-17.2018 · Cited by 106 · see citing works

Right Time, Right Place: Probing the Functions of Organelle Positioning

van Bergeijk, P., Hoogenraad, C. C., & Kapitein, L. C. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.10.001 · Cited by 111 · see citing works

Powerhouse of the mind: mitochondrial plasticity at the synapse

Rossi, M., & Pekkurnaz, G. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2019.02.001 · Cited by 110 · see citing works

Cytoskeletal and signaling mechanisms of neurite formation

Sainath, R., & Gallo, G. (2015) · Cell and Tissue Research · doi:10.1007/s00441-014-1955-0 · Cited by 103 · see citing works

Mechanisms for the maintenance and regulation of axonal energy supply

Chamberlain, K. A., & Sheng, Z. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24411 · Cited by 105 · see citing works

Mitochondria are Naturally Micro Robots - A review

Aversa, R. M., Petrescu, R. V., Apicella, A. M., & Petrescu, F. I. T. (2016) · American Journal of Engineering and Applied Sciences · doi:10.3844/ajeassp.2016.991.1002 · Cited by 108 · see citing works

Mitochondrial calcium cycling in neuronal function and neurodegeneration

Walters, G. C., & Usachev, Y. M. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1094356 · Cited by 105 · see citing works

Mitochondria as central hubs in synaptic modulation

Duarte, F. V., Ciampi, D., & Duarte, C. B. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-04814-8 · Cited by 99 · see citing works

Allostatic load and comorbidities: A mitochondrial, epigenetic, and evolutionary perspective

Juster, R., Russell, J. J., Almeida, D., & Picard, M. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000730 · Cited by 87 · see citing works

Axonal energy metabolism, and the effects in aging and neurodegenerative diseases

Yang, S., Park, J. H., & Lu, H.-C. (2023) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00634-3 · Cited by 94 · see citing works

Development of novel phosphodiesterase 5 inhibitors for the therapy of Alzheimer’s disease

Zuccarello, E., Acquarone, E., Calcagno, E., Argyrousi, E. K., Deng, S., Landry, D. W., Arancio, O., & Fiorito, J. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.113818 · Cited by 93 · see citing works

Mitochondria in Neuronal Health: From Energy Metabolism to Parkinson's Disease

Mahadevan, H. M., Hashemiaghdam, A., Ashrafi, G., & Harbauer, A. B. (2021) · Advanced Biology · doi:10.1002/adbi.202100663 · Cited by 106 · see citing works

Roles for neuronal and glial autophagy in synaptic pruning during development

Lieberman, O. J., McGuirt, A. F., Tang, G., & Sulzer, D. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.04.017 · Cited by 87 · see citing works

Mitochondrial Ca2+ uptake by the MCU facilitates pyramidal neuron excitability and metabolism during action potential firing

Groten, C. J., & MacVicar, B. A. (2022) · Communications Biology · doi:10.1038/s42003-022-03848-1 · Cited by 89 · see citing works

Mitochondrial Dynamics in Visual Cortex Are Limited In Vivo and Not Affected by Axonal Structural Plasticity

Smit‐Rigter, L. A., Rajendran, R., Silva, C. A., Spierenburg, L., Groeneweg, F. L., Ruimschotel, E., van Versendaal, D., van der Togt, C., Eysel, U. T., Heimel, J. A., et al. (2016) · Current Biology · doi:10.1016/j.cub.2016.07.033 · Cited by 88 · see citing works

Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia

Huang, N., Li, S., Xie, Y., Han, Q., Xu, X., & Sheng, Z. (2021) · Current Biology · doi:10.1016/j.cub.2021.04.079 · Cited by 88 · see citing works

Mitochondrial calcium at the synapse

Datta, S., & Jaiswal, M. (2021) · Mitochondrion · doi:10.1016/j.mito.2021.04.006 · Cited by 73 · see citing works

Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer's disease pathogenesis

Cao, J., Zhong, M. B., Toro, C. A., Zhang, L., & Cai, D. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.03.016 · Cited by 80 · see citing works

Aging: All roads lead to mitochondria

Son, J. M., & Lee, C. D. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.02.006 · Cited by 82 · see citing works

Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I

Zimin, P. I., Woods, C. B., Kayser, E. B., Ramirez, J. M., Morgan, P. G., & Sedensky, M. M. (2018) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.01.036 · Cited by 76 · see citing works

Differential presynaptic ATP supply for basal and high-demand transmission

Sobieski, C., Fitzpatrick, M. J., & Mennerick, S. J. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.2712-16.2017 · Cited by 74 · see citing works

Mitochondrial Calcium Uptake Modulates Synaptic Vesicle Endocytosis in Central Nerve Terminals

Marland, J. R. K., Hasel, P., Bonnycastle, K., & Cousin, M. A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.686956 · Cited by 71 · see citing works

Mechanics of mitochondrial motility in neurons

Barnhart, E. L. (2016) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2016.02.022 · Cited by 68 · see citing works

Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer's disease

Sayehmiri, F., Motamedi, F., Batool, Z., Naderi, N., Shaerzadeh, F., Zoghi, A., Rezaei, O., Khodagholi, F., & Pourbadie, H. G. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14897 · Cited by 66 · see citing works

Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A

Zhu, P.-P., Denton, K. R., Pierson, T. M., Li, X.-J., & Blackstone, C. D. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu280 · Cited by 65 · see citing works

The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction

Liu, H. Y., Gale, J. R., Reynolds, I. J., Weiss, J. H., & Aizenman, E. (2021) · Biomedicines · doi:10.3390/biomedicines9050489 · Cited by 64 · see citing works

Oxidative stress and synaptic dysfunction in rodent models of Parkinson's disease

Imbriani, P., Martella, G., Bonsi, P., & Pisani, A. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105851 · Cited by 61 · see citing works

Mitochondrial fission is an acute and adaptive response in injured motor neurons

Kiryu‐Seo, S., Tamada, H., Kato, Y., Yasuda, K., Ishihara, N., Nomura, M., Mihara, K., & Kiyama, H. (2016) · Scientific Reports · doi:10.1038/srep28331 · Cited by 61 · see citing works

Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice

Rosenberg, A. M., Saggar, M., Monzel, A. S., Devine, J., Rogu, P. J., Limoges, A., Junker, A., Sandi, C., Mosharov, E. V., Dumitriu, D., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-39941-0 · Cited by 60 · see citing works

Mitochondrial synapses: intracellular communication and signal integration

Picard, M. A. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.06.001 · Cited by 56 · see citing works

Inhibiting the Mitochondrial Calcium Uniporter during Development Impairs Memory in Adult Drosophila

Drago, I., & Davis, R. L. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.08.017 · Cited by 57 · see citing works

Morphology of mitochondria in spatially restricted axons revealed by cryo-electron tomography

Fischer, T. D., Dash, P. K., Liu, J., & Waxham, M. N. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2006169 · Cited by 56 · see citing works

Glycolysis selectively shapes the presynaptic action potential waveform

Lujan, B., Kushmerick, C., Banerjee, T. D., Dagda, R. K., & Renden, R. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00629.2016 · Cited by 56 · see citing works

Intracellular Ca 2+ Release and Synaptic Plasticity: A Tale of Many Stores

Padamsey, Z., Foster, W. J., & Emptage, N. J. (2018) · The Neuroscientist · doi:10.1177/1073858418785334 · Cited by 56 · see citing works

Dysfunctional Mitochondrial Bioenergetics and Synaptic Degeneration in Alzheimer Disease

Tang, J. J., Oliveros, A., & Jang, M. (2019) · International Neurourology Journal · doi:10.5213/inj.1938036.018 · Cited by 56 · see citing works

Mesenchymal Stem/Stromal Cell-Mediated Mitochondrial Transfer and the Therapeutic Potential in Treatment of Neurological Diseases

Han, D., Zheng, X., Wang, X., Jin, T., Cui, L., & Chen, Z. (2020) · Stem Cells International · doi:10.1155/2020/8838046 · Cited by 56 · see citing works

Fluid intelligence and the locus coeruleus–norepinephrine system

Tsukahara, J. S., & Engle, R. W. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2110630118 · Cited by 56 · see citing works

Central presynaptic terminals are enriched in ATP but the majority lack mitochondria

Chavan, V., Willis, J., Walker, S. K., Clark, H. R., Liu, X., Fox, M. A., Srivastava, S., & Mukherjee, K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0125185 · Cited by 52 · see citing works

The Mitochondrial Complex V–Associated Large-Conductance Inner Membrane Current Is Regulated by Cyclosporine and Dexpramipexole

Alavian, K. N., Dworetzky, S. I., Bonanni, L., Zhang, P., Sacchetti, S., Li, H., Signore, A. P., Smith, P. J., Gribkoff, V. K., & Jonas, E. A. (2014) · Molecular Pharmacology · doi:10.1124/mol.114.095661 · Cited by 50 · see citing works

Developmental regulation of microtubule‐based trafficking and anchoring of axonal mitochondria in health and diseases

Cheng, X., & Sheng, Z. (2020) · Developmental Neurobiology · doi:10.1002/dneu.22748 · Cited by 50 · see citing works

Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons

Kochan, S. M. V., Malo, M. C., Jevtic, M., Jahn-Kelleter, H. M., Wani, G. A., Ndoci, K., Pérez-Revuelta, L., Gaedke, F., Schäffner, I., Lie, D. C., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.03.013 · Cited by 50 · see citing works

Bcl-xL in neuroprotection and plasticity

Jonas, E. A., Porter, G. A., Jr., & Alavian, K. N. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00355 · Cited by 48 · see citing works

Concepts of Neuroinflammation and Their Relationship With Impaired Mitochondrial Functions in Bipolar Disorder

Cyrino, L. A. R., de Lima, D. D., Ullmann, O. M., & Maia, T. P. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.609487 · Cited by 48 · see citing works

Presynaptic Boutons That Contain Mitochondria Are More Stable

Lees, R. M., Johnson, J. D., & Ashby, M. C. (2020) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2019.00037 · Cited by 45 · see citing works

Social Inequalities and the Road to Allostatic Load: From Vulnerability to Resilience

Juster, R., Seeman, T. E., McEwen, B. S., Picard, M. A., Mahar, I., Mechawar, N., Sindi, S., Smith, N. G., Souza‐Talarico, J. N., Sarnyai, Z., et al. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy408 · Cited by 45 · see citing works

Lactate as a supplemental fuel for synaptic transmission and neuronal network oscillations: Potentials and limitations

Kann, O. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15867 · Cited by 44 · see citing works

Biomaterials reinforced MSCs transplantation for spinal cord injury repair

Ma, T., Wu, J., Mu, J., & Gao, J. (2021) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2021.03.003 · Cited by 42 · see citing works

Regulation of axonal mitochondrial transport and its impact on synaptic transmission

Cai, Q., Davis, M. L., & Sheng, Z. (2011) · Neuroscience Research · doi:10.1016/j.neures.2011.02.005 · Cited by 85 · see citing works

Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation

Kang, J.-S., Tian, J.-H., Pan, P.-Y., Zald, P., Li, C., Deng, C., & Sheng, Z.-H. (2008) · Cell · doi:10.1016/j.cell.2007.11.024 · Cited by 598 · see citing works

Presynaptic Boutons That Contain Mitochondria Are More Stable

Lees, R. M., Johnson, J. D., & Ashby, M. C. (2020) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2019.00037 · Cited by 45 · see citing works

Regulation of mitochondrial dynamics and distribution by synapse position and neuronal activity in the axon

Obashi, K., & Okabe, S. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12263 · Cited by 88 · see citing works

Regulation of Synaptic Transmission through Mitochondrial Positioning and Metabolism

Li, S., & Sheng, Z. (2024) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190932183.013.13