The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
The PAR Proteins: Fundamental Players in Animal Cell Polarization
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Asymmetric cell divisions promote stratification and differentiation of mammalian skin
Lechler, T., & Fuchs, E. (2005) · Nature · doi:10.1038/nature03922 · Cited by 998
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
Joberty, G., Petersen, C., Gao, L., & Macara, I. G. (2000) · Nature Cell Biology · doi:10.1038/35019573 · Cited by 928
Self-citationDrewes, G., Ebneth, A., Preuss, U., Mandelkow, E.-M., & Mandelkow, E. (1997) · Cell · doi:10.1016/s0092-8674(00)80208-1 · Cited by 878
A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
Lin, D., Edwards, A. S., Fawcett, J. P., Mbamalu, G., Scott, J. D., & Pawson, T. (2000) · Nature Cell Biology · doi:10.1038/35019582 · Cited by 743
Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity
Shi, S.-H., Jan, L. Y., & Jan, Y.-N. (2003) · Cell · doi:10.1016/s0092-8674(02)01249-7 · Cited by 600
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
Wallingford, J. B., & Habas, R. (2005) · Development · doi:10.1242/dev.02068 · Cited by 509
Integrated activity of PDZ protein complexes regulates epithelial polarity
Bilder, D., Schober, M., & Perrimon, N. (2003) · Nature Cell Biology · doi:10.1038/ncb897 · Cited by 435
Macara, I. G. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1332 · Cited by 341
Self-citationYamanaka, T., Horikoshi, Y., Suzuki, A., Sugiyama, Y., Kitamura, K., Maniwa, R., Nagai, Y., Yamashita, A., Hirose, T., Ishikawa, H., et al. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00453.x · Cited by 306
Harris, T. J. C., & Peifer, M. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200505127 · Cited by 295
Cited by
Mammalian Rho GTPases: new insights into their functions from in vivo studies
Heasman, S. J., & Ridley, A. J. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2476 · Cited by 1,871
Luissint, A.-C., Artus, C., Glacial, F., Ganeshamoorthy, K., & Couraud, P.-O. (2012) · Fluids and Barriers of the CNS · doi:10.1186/2045-8118-9-23 · Cited by 654
“The participation of this PCP complex to TJ integrity was further illustrated by the recent observation that meningococcal adhesion to human cerebral endothelial cells recruited Par-3, Par-6 and aPKC-ζ under bacterial colonies and induced disruption of cell-cell junctions [156].”
InfluentialCoordinated protein sorting, targeting and distribution in polarized cells
Mellman, I., & Nelson, W. J. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2525 · Cited by 521
Establishment of axon-dendrite polarity in developing neurons.
Barnes, A. P., & Polleux, F. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125536 · Cited by 523
Crosstalk between small GTPases and polarity proteins in cell polarization
Iden, S., & Collard, J. G. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2521 · Cited by 451
Apical constriction: A cell shape change that can drive morphogenesis
Sawyer, J. M., Harrell, J. R., Shemer, G., Sullivan-Brown, J., Roh-Johnson, M., & Goldstein, B. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.09.009 · Cited by 448
Self-citationRho and Ras GTPases in axon growth, guidance, and branching
Hall, A., & Lalli, G. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001818 · Cited by 437
Mechanisms of Stomatal Development
Pillitteri, L. J., & Torii, K. U. (2012) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105451 · Cited by 389
Endocytosis and signaling: Cell logistics shape the eukaryotic cell plan
Sigismund, S., Confalonieri, S., Ciliberto, A., Polo, S., Scita, G., & Di Fiore, P. P. (2012) · Physiological Reviews · doi:10.1152/physrev.00005.2011 · Cited by 338
Tepass, U. (2012) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154033 · Cited by 334
Polarity proteins in migration and invasion
Etienne-Manneville, S. (2008) · Oncogene · doi:10.1038/onc.2008.347 · Cited by 295
Control of synapse development and plasticity by Rho GTPase regulatory proteins
Tolias, K. F., Duman, J. G., & Um, K. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.04.011 · Cited by 261
Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
Hao, Y., Du, Q., Chen, X., Zheng, Z., Balsbaugh, J. L., Maitra, S., Shabanowitz, J., Hunt, D. F., & Macara, I. G. (2010) · Current Biology · doi:10.1016/j.cub.2010.09.032 · Cited by 230
Self-citationProtein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli
Dine, E., Gil, A. A., Uribe, G., Brangwynne, C. P., & Toettcher, J. E. (2018) · Cell Systems · doi:10.1016/j.cels.2018.05.002 · Cited by 182
Schmoranzer, J., Fawcett, J. P., Segura, M., Tan, S., Vallee, R. B., Pawson, T., & Gundersen, G. G. (2009) · Current Biology · doi:10.1016/j.cub.2009.05.065 · Cited by 192
Epithelial cell–cell junctions and plasma membrane domains
Giepmans, B. N. G., & van IJzendoorn, S. C. D. (2009) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.07.015 · Cited by 170
Sculpting Organs: Mechanical Regulation of Tissue Development
Nelson, C. M., & Gleghorn, J. P. (2012) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071811-150043 · Cited by 130
Stephens, R., Lim, K., Portela, M., Kvansakul, M., Humbert, P. O., & Richardson, H. E. (2018) · Journal of Molecular Biology · doi:10.1016/j.jmb.2018.01.011 · Cited by 132
The Biological Functions and Signaling Mechanisms of the p75 Neurotrophin Receptor
Kraemer, B. R., Yoon, S. O., & Carter, B. D. (2014) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-45106-5_6 · Cited by 125
LKB1 is essential for the proliferation of T‐cell progenitors and mature peripheral T cells
Tamás, P., Macintyre, A., Finlay, D., Clarke, R., Feijoo‐Carnero, C., Ashworth, A., & Cantrell, D. (2010) · European Journal of Immunology · doi:10.1002/eji.200939677 · Cited by 94
RalA and the exocyst complex influence neuronal polarity through PAR-3 and aPKC
Lalli, G. (2009) · Journal of Cell Science · doi:10.1242/jcs.044339 · Cited by 84
Chen, S., Chen, J., Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., & Shi, S.-H. (2013) · Developmental Cell · doi:10.1016/j.devcel.2012.11.014 · Cited by 82
Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium
Ivanov, A. I., Young, C., Beste, K. D., Capaldo, C. T., Humbert, P. O., Brennwald, P., Parkos, C. A., & Nusrat, A. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.090220 · Cited by 73
PAR-1 kinase regulates epithelial detachment and directional protrusion of migrating border cells
McDonald, J. A., Khodyakova, A., Aranjuez, G., Dudley, C., & Montell, D. J. (2008) · Current Biology · doi:10.1016/j.cub.2008.09.041 · Cited by 63
Scribble, Erbin, and Lano redundantly regulate epithelial polarity and apical adhesion complex
Choi, J., Troyanovsky, R. B., Indra, I., Mitchell, B. J., & Troyanovsky, S. M. (2019) · Journal of Cell Biology · doi:10.1083/jcb.201804201 · Cited by 53
de Vreede, G., Schoenfeld, J. D., Windler, S. L., Morrison, H., Lu, H., & Bilder, D. (2014) · Development · doi:10.1242/dev.105403 · Cited by 50
Dynamic regulation of GEF-H1 localization at microtubules by Par1b/MARK2
Yoshimura, Y., & Miki, H. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.04.032 · Cited by 39
ERK2-mediated phosphorylation of Par3 regulates neuronal polarization.
Funahashi, Y., Namba, T., Fujisue, S., Itoh, N., Nakamuta, S., Kato, K., Shimada, A., Xu, C., Shan, W., Nishioka, T., et al. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.4210-12.2013 · Cited by 38
Epidermal Polarity Genes in Health and Disease
Tellkamp, F., Vorhagen, S., & Niessen, C. M. (2014) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a015255 · Cited by 33
Pasten, C., Cerda, J., Jausoro, I., Court, F. A., Cáceres, A., & Marzolo, M.-P. (2015) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2015.09.004 · Cited by 29
Chen, D.-Y., Sun, N.-H., Lu, Y.-P., Hong, L.-J., Cui, T.-T., Wang, C.-K., Chen, X.-H., Wang, S.-S., Feng, L.-L., Shi, W.-X., et al. (2019) · Theranostics · doi:10.7150/thno.34168 · Cited by 29
Sun, M., Asghar, S. Z., & Zhang, H. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.03.022 · Cited by 26
Metadata
- Authors
- Goldstein, B., & Macara, I. G.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2007-11
- Volume
- 13
- Issue
- 5
- Pages
- 609-622
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W2161930851
- Cited by
- 758
- References
- 14
- FWCI
- 19.88
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
