Psilocybin-assisted therapy of major depressive disorder using Acceptance and Commitment Therapy as a therapeutic frame
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The rationale for integrating ACT principles into the psilocybin-assisted therapy model stems from proposed concordance between mechanisms of change generated by both approaches.
“The rationale for integrating ACT principles into the PAT model stems from the proposed concordance between mechanisms of change generated by both approaches, as the psychedelic experience may provide direct experiential access to key ACT processes known to enhance psychological flexibility (see [87] for an in-depth discussion).”
Debate continues over which therapeutic modalities best complement psychedelic treatment, with various adapted and ad hoc models being evaluated in clinical research presently.
“Debate continues over which therapeutic modalities best complement psychedelic treatment (110–112), with various adapted and ad hoc models being evaluated in clinical research presently (106).”
From Psychoanalytically informed MDMA-assisted therapy for pathological narcissism: a novel theoretical approach (2025) · cites this paper as [112]
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Historicizing psychedelics: counterculture, renaissance, and the neoliberal matrix
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Psilocybin, an Effective Treatment for Major Depressive Disorder in Adults - A Systematic Review
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The science of psychedelic medicine
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Will psilocybin lose its magic in the clinical setting?
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Psychedelics and Evidence-based Psychotherapy
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Expert Opinion on Psychedelic-Assisted Psychotherapy for People with Psychotic SymptomsPreprint
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Self-citationPsilocybin: From Psychiatric Pariah to Perceived Panacea
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Recalled childhood trauma and post-psychedelic trajectories of change in a mixed-methods study
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“…principles into the PAT model stems from the proposed concordance between mechanisms of change generated by both approaches, as the psychedelic experience may provide direct experiential access to key ACT processes known to enhance psychological flexibility (see [87] for an in-depth discussion).”
BackgroundKey competencies for psychedelic treatment in real-world mental health care settings
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Psychedelic-Assisted Psychotherapy and Mindfulness-Based Cognitive Therapy: Potential Synergies
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Study protocol for “Psilocybin in patients with fibromyalgia: brain biomarkers of action”
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Psychedelic therapy as reality transformation: A phenomenological approach
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Knowledge gaps in psychedelic medicalisation: Clinical studies and regulatory aspects
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Psychedelic use and psychological flexibility: The role of meaningful intention and decentering
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Mystical experiences without mysticism: An argument for mystical fictionalism in psychedelics
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INTEGRATING PSYCHEDELIC EXPERIENCES UTILIZING THE INTERNAL FAMILY SYSTEMS THERAPEUTIC MODEL
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EMBARK Psychedelic Therapy for Depression
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Editorial: The psychotherapeutic framing of psychedelic drug administration
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Psychedelic-assisted Psychotherapy in 3-D: Acceptance, Connectedness, and Defensiveness
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Critical Period Plasticity as a Framework for Psychedelic-Assisted Psychotherapy
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Clinical Utility of Mystical Experiences: An Overview and Conceptual Framework
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Serotonergic psychedelics for depression: A comprehensive overview
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Self-citation
- Authors
- Sloshower, J., Guss, J., Krause, R., Wallace, R. M., Williams, M. T., Reed, S., & Skinta, M. D.
- Affiliations
- Yale University (US)
- NYU Langone Health (US)
- University of Connecticut (US)
- Roosevelt University (US)
- Corresponding author
- Sloshower, Jordan
- Venue
- Journal of Contextual Behavioral Science
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 15
- Pages
- 12-19
- ISSN
- 2212-1447 (ISSN-L)
- OpenAlex
- W2984820573
- Cited by
- 171
- References
- 51
- Citations by year
- 2026: 23 · 2025: 26 · 2024: 43 · 2023: 26 · 2022: 24 · 2021: 15 · 2020: 12
- FWCI
- 14.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Contextual Behavioral Science (publishedVersion)
- Funders
- Heffter Research Institute
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- psilocybin-assisted therapy, major depressive disorder, acceptance and commitment therapy, psychedelic therapy, psychological flexibility, mechanisms of change
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