The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

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Biliary Acute Pancreatitis in Mice is Mediated by the G-Protein−Coupled Cell Surface Bile Acid Receptor Gpbar1

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Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

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Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells

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Nongenomic Actions of Bile Acids. Synthesis and Preliminary Characterization of 23- and 6,23-Alkyl-Substituted Bile Acid Derivatives as Selective Modulators for the G-Protein Coupled Receptor TGR5

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Hypertrophic Cardiomyopathy and Dysregulation of Cardiac Energetics in A Mouse Model of Biliary Fibrosis

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Postprandial plasma bile acid responses in normal weight and obese subjects

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Identification of a bile acid response element in the cholesterol 7 alpha-hydroxylase gene CYP7A

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Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice

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Discovery of 3-Aryl-4-isoxazolecarboxamides as TGR5 Receptor Agonists

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Plasma bile acids are not associated with energy metabolism in humans

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Inhibition of Tumor Necrosis Factor-Alpha and lnterleukin-1-Beta Production by Beta-Adrenoceptor Agonists from Lipopolysaccharide- Stimulated Human Peripheral Blood Mononuclear Cells

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Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes

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Effect of Colestimide Therapy for Glycemic Control in Type 2 Diabetes Mellitus with Hypercholesterolemia

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In Vivo Imaging of Farnesoid X Receptor Activity Reveals the Ileum as the Primary Bile Acid Signaling Tissue

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Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors

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Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5

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The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts

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Deoxycholic Acid Conjugates Are Muscarinic Cholinergic Receptor Antagonists

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Redefining the TGR5 Triterpenoid Binding Pocket at the C‐3 Position

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Molecular Field Analysis and 3D-Quantitative Structure−Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5

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Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

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Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome

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The role of the microbiome in NAFLD and NASH

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The bile acid TGR5 membrane receptor: from basic research to clinical application

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Small metabolites, possible big changes: A microbiota-centered view of non-alcoholic fatty liver disease

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Connecting the immune system, systemic chronic inflammation and the gut microbiome: the role of sex

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Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis

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Daily eating patterns and their impact on health and disease

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Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells

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Novel therapeutic targets for cholestatic and fatty liver disease

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The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice

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Targeting fatty acid metabolism to improve glucose metabolism

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TGR5 regulates macrophage inflammation in nonalcoholic steatohepatitis by modulating NLRP3 inflammasome activation

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The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases

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Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

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The road ahead for health and lifespan interventions

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Nonalcoholic fatty liver disease – current status and future directions

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Role of TGR5 (GPBAR1) in Liver Disease

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Bile Acid-Activated Receptors: GPBAR1 (TGR5) and Other G Protein-Coupled Receptors

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The G-protein-coupled bile acid receptor Gpbar1 (TGR5) inhibits gastric inflammation through antagonizing NF-κB signaling pathway

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Bile salt hydrolase: The complexity behind its mechanism in relation to lowering-cholesterol lactobacilli probiotics

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Potential Protective Effect of Oleanolic Acid on the Components of Metabolic Syndrome: A Systematic Review

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TGR5 signaling mitigates parenteral nutrition-associated liver disease

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Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes

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Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction

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Developments in bile salt based therapies: A critical overview

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Bile acid metabolism and signaling in liver disease and therapy

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