Dynamics of awake hippocampal-prefrontal replay for spatial learning and memory-guided decision making
Open accessPublished version of a preprint
Abstract
SUMMARY Spatial learning requires remembering and choosing paths to goals. Hippocampal place cells replay spatial paths during immobility in reverse and forward order, offering a potential mechanism. However, how replay supports both goal-directed learning and memory-guided decision making is unclear. We therefore continuously tracked awake replay in the same hippocampal-prefrontal ensembles throughout learning of a spatial alternation task. We found that during pauses between behavioral trajectories, reverse and forward hippocampal replay support an internal cognitive search of available past and future possibilities, and exhibit opposing learning gradients for prediction of past and future behavioral paths, respectively. Coordinated hippocampal-prefrontal replay distinguished correct past and future paths from alternative choices, suggesting a role in recall of past paths to guide planning of future decisions for spatial working memory. Our findings reveal a learning shift from hippocampal reverse-replay-based retrospective evaluation to forward-replay-based prospective planning, with prefrontal read-out of memory-guided paths for learning and decision-making.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Reactivation of ensemble firing patterns occurs during quiet rest and active behavior in rodents and humans, as well as during sleep.
“Reactivation of ensemble firing patterns was first identified during sleep, 79,136 but the phenomenon occurs likewise during quiet rest as well as during active behavior, in rodents 80,81,137,138 as well as in humans.”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [138]
Offline replay of ensemble firing patterns in conjunction with hippocampal ripples occurs also during quiet wakefulness.
“However, the offline replay of ensemble firing patterns in conjunction with hippocampal ripples occurs also during quiet wakefulness.138,150”
From Sleep—A brain-state serving systems memory consolidation (2023) · cites this paper as [138]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
LIBSVM: A library for support vector machines
Chang, C.-C., & Lin, C.-J. (2011) · ACM Transactions on Intelligent Systems and Technology · doi:10.1145/1961189.1961199 · Cited by 40,918 · see citing works
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010 · see citing works
Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.2.195 · Cited by 5,376 · see citing works
The hippocampus as a cognitive map
Passingham, R. E. (1979) · Neuroscience · doi:10.1016/0306-4522(79)90015-0 · Cited by 5,128 · see citing works
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates
Paxinos, G., WATSON, C. R. R., & Emson, P. C. (1980) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(80)90021-7 · Cited by 4,497 · see citing works
Hippocampal sharp wave-ripple: A cognitive biomarker for episodic memory and planning
Buzsáki, G. (2015) · Hippocampus · doi:10.1002/hipo.22488 · Cited by 1,759 · see citing works
Reverse replay of behavioural sequences in hippocampal place cells during the awake state
Foster, D. J., & Wilson, M. A. (2006) · Nature · doi:10.1038/nature04587 · Cited by 1,727 · see citing works
Packard, M. G., & McGaugh, J. L. (1996) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1996.0007 · Cited by 1,505 · see citing works
Hippocampal place-cell sequences depict future paths to remembered goals
Pfeiffer, B. E., & Foster, D. J. (2013) · Nature · doi:10.1038/nature12112 · Cited by 1,216 · see citing works
Forward and reverse hippocampal place-cell sequences during ripples
Diba, K., & Buzsáki, G. (2007) · Nature Neuroscience · doi:10.1038/nn1961 · Cited by 1,205 · see citing works
From Conditioning to Conscious Recollection
Eichenbaum, H., & Cohen, N. J. (2004) · doi:10.1093/acprof:oso/9780195178043.001.0001 · Cited by 1,026 · see citing works
Wood, E. R., Dudchenko, P. A., Robitsek, R. J., & Eichenbaum, H. (2000) · Neuron · doi:10.1016/s0896-6273(00)00071-4 · Cited by 992 · see citing works
Hippocampal replay in the awake state: a potential substrate for memory consolidation and retrieval
Carr, M. F., Jadhav, S. P., & Frank, L. M. (2011) · Nature Neuroscience · doi:10.1038/nn.2732 · Cited by 958 · see citing works
Self-citationAwake hippocampal sharp-wave ripples support spatial memory
Jadhav, S. P., Kemere, C., German, P. W., & Frank, L. M. (2012) · Science · doi:10.1126/science.1217230 · Cited by 924 · see citing works
Self-citationThe cognitive map in humans: spatial navigation and beyond
Epstein, R. A., Patai, E. Z., Julian, J. B., & Spiers, H. J. (2017) · Nature Neuroscience · doi:10.1038/nn.4656 · Cited by 921 · see citing works
Benchenane, K., Peyrache, A., Khamassi, M., Tierney, P. L., Gioanni, Y., Battaglia, F. P., & Wiener, S. I. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.013 · Cited by 872 · see citing works
Prefrontal–hippocampal interactions in episodic memory
Eichenbaum, H. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.74 · Cited by 870 · see citing works
Hippocampal replay of extended experience
Davidson, T. J., Kloosterman, F., & Wilson, M. A. (2009) · Neuron · doi:10.1016/j.neuron.2009.07.027 · Cited by 806 · cited 5× · see citing works
“47 cm) was comparable to previous reports (Ambrose et al., 2016; Davidson et al., 2009; Farooq and Dragoi, 2019; O’Neill et al., 2017).”
BackgroundMethodResultInfluentialAwake replay of remote experiences in the hippocampus
Karlsson, M. P., & Frank, L. M. (2009) · Nature Neuroscience · doi:10.1038/nn.2344 · Cited by 769 · cited 7× · see citing works
“The assessment of replay events for significance was implemented as previously described (Karlsson and Frank, 2009).”
BackgroundMethodInfluentialThe reorganization and reactivation of hippocampal maps predict spatial memory performance
Dupret, D., O'Neill, J., Pleydell-Bouverie, B., & Csicsvari, J. (2010) · Nature Neuroscience · doi:10.1038/nn.2599 · Cited by 769 · see citing works
Replay of rule-learning related neural patterns in the prefrontal cortex during sleep
Peyrache, A., Khamassi, M., Benchenane, K., Wiener, S. I., & Battaglia, F. P. (2009) · Nature Neuroscience · doi:10.1038/nn.2337 · Cited by 767 · see citing works
Kudrimoti, H. S., Barnes, C. A., & McNaughton, B. L. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-10-04090.1999 · Cited by 753 · see citing works
Hippocampal replay is not a simple function of experience
Gupta, A. S., van der Meer, M. A. A., Touretzky, D. S., & Redish, A. D. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.034 · Cited by 733 · see citing works
Trajectory Encoding in the Hippocampus and Entorhinal Cortex
Frank, L. M., Brown, E. N., & Wilson, M. A. (2000) · Neuron · doi:10.1016/s0896-6273(00)00018-0 · Cited by 731 · see citing works
Preplay of future place cell sequences by hippocampal cellular assemblies
Dragoi, G., & Tonegawa, S. (2011) · Nature · doi:10.1038/nature09633 · Cited by 716 · see citing works
Hippocampal–prefrontal input supports spatial encoding in working memory
Spellman, T., Rigotti, M., Ahmari, S. E., Fusi, S., Gogos, J. A., & Gordon, J. A. (2015) · Nature · doi:10.1038/nature14445 · Cited by 693 · see citing works
Behavior-dependent short-term assembly dynamics in the medial prefrontal cortex
Fujisawa, S., Amarasingham, A., Harrison, M. T., & Buzsáki, G. (2008) · Nature Neuroscience · doi:10.1038/nn.2134 · Cited by 679 · see citing works
Quantitative measures of cluster quality for use in extracellular recordings
Schmitzer-Torbert, N. C., Jackson, J. C., Henze, D. A., Harris, K., & Redish, A. D. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.09.066 · Cited by 642 · see citing works
Fast-Forward Playback of Recent Memory Sequences in Prefrontal Cortex During Sleep
Euston, D. R., Tatsuno, M., & McNaughton, B. L. (2007) · Science · doi:10.1126/science.1148979 · Cited by 586 · see citing works
Prospective and Retrospective Memory Coding in the Hippocampus
Ferbinteanu, J., & Shapiro, M. L. (2003) · Neuron · doi:10.1016/s0896-6273(03)00752-9 · Cited by 560 · see citing works
Human replay spontaneously reorganizes experience
Liu, Y., Dolan, R. J., Kurth-Nelson, Z., & Behrens, T. E. J. (2019) · Cell · doi:10.1016/j.cell.2019.06.012 · Cited by 497 · see citing works
Long-duration hippocampal sharp wave ripples improve memory
Fernández-Ruiz, A., Oliva, A., Fermino de Oliveira, E., Rocha-Almeida, F., Tingley, D., & Buzsáki, G. (2019) · Science · doi:10.1126/science.aax0758 · Cited by 490 · see citing works
A prefrontal–thalamo–hippocampal circuit for goal-directed spatial navigation
Ito, H., Zhang, S.-J., Witter, M. P., Moser, E. I., & Moser, M. (2015) · Nature · doi:10.1038/nature14396 · Cited by 483 · see citing works
Redish, A. D. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2015.30 · Cited by 462 · see citing works
The hippocampal sharp wave-ripple in memory retrieval for immediate use and consolidation
Joo, H. R., & Frank, L. M. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0077-1 · Cited by 430 · see citing works
Hippocampal-cortical interaction during periods of subcortical silence
Logothetis, N. K., Eschenko, O., Murayama, Y., Augath, M., Steudel, T., Evrard, H. C., Besserve, M., & Oeltermann, A. (2012) · Nature · doi:10.1038/nature11618 · Cited by 420 · see citing works
The Role of the Hippocampus in Prediction and Imagination
Buckner, R. L. (2010) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163508 · Cited by 419 · see citing works
Hippocampal Plasticity across Multiple Days of Exposure to Novel Environments
Frank, L. M., Stanley, G. B., & Brown, E. N. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1958-04.2004 · Cited by 410 · see citing works
Hippocampus leads ventral striatum in replay of place-reward information
Lansink, C. S., Goltstein, P. M., Lankelma, J. V., McNaughton, B. L., & Pennartz, C. M. A. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000173 · Cited by 400 · see citing works
Prioritized memory access explains planning and hippocampal replay
Mattar, M. G., & Daw, N. D. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0232-z · Cited by 393 · see citing works
Multisensory Control of Hippocampal Spatiotemporal Selectivity
Ravassard, P., Kees, A. L., Willers, B., Ho, D. G., Aharoni, D. B., Cushman, J. D., Aghajan, Z. M., & Mehta, M. R. (2013) · Science · doi:10.1126/science.1232655 · Cited by 388 · see citing works
A cortical-hippocampal-cortical loop of information processing during memory consolidation
Rothschild, G., Eban, E., & Frank, L. M. (2017) · Nature Neuroscience · doi:10.1038/nn.4457 · Cited by 387 · see citing works
Rewarded Outcomes Enhance Reactivation of Experience in the Hippocampus
Singer, A. C., & Frank, L. M. (2009) · Neuron · doi:10.1016/j.neuron.2009.11.016 · Cited by 385 · see citing works
The ubiquity of model-based reinforcement learning
Doll, B. B., Simon, D. A., & Daw, N. D. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.08.003 · Cited by 380 · see citing works
Foster, D. J. (2017) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-072116-031538 · Cited by 375 · see citing works
Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus
Khodagholy, D., Gelinas, J. N., & Buzsáki, G. (2017) · Science · doi:10.1126/science.aan6203 · Cited by 357 · see citing works
Dynamics of Population Code for Working Memory in the Prefrontal Cortex
Baeg, E. H., Kim, Y. B., Huh, K., Mook-Jung, I., Kim, H. T., & Jung, M. W. (2003) · Neuron · doi:10.1016/s0896-6273(03)00597-x · Cited by 338 · see citing works
Dynamic Analysis of Learning in Behavioral Experiments
Smith, A. C., Frank, L. M., Wirth, S., Yanike, M., Hu, D., Kubota, Y., Graybiel, A. M., SUZUKI, W. A., & Brown, E. N. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2908-03.2004 · Cited by 313 · see citing works
Sullivan, D. W., Csicsvari, J. L., Mizuseki, K., Montgomery, S. M., Diba, K., & Buzsáki, G. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0294-11.2011 · Cited by 292 · see citing works
Reverse replay of hippocampal place cells is uniquely modulated by changing reward
Ambrose, R. E., Pfeiffer, B. E., & Foster, D. J. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.047 · Cited by 292 · see citing works
New Experiences Enhance Coordinated Neural Activity in the Hippocampus
Cheng, S., & Frank, L. M. (2008) · Neuron · doi:10.1016/j.neuron.2007.11.035 · Cited by 286 · see citing works
Singer, A. C., Carr, M. F., Karlsson, M. P., & Frank, L. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.027 · Cited by 270 · see citing works
Hippocampal sharp-wave ripples linked to visual episodic recollection in humans
Norman, Y., Yeagle, E. M., Khuvis, S., Harel, M., Mehta, A. D., & Malach, R. (2019) · Science · doi:10.1126/science.aax1030 · Cited by 270 · see citing works
Coupled ripple oscillations between the medial temporal lobe and neocortex retrieve human memory
Vaz, A. P., Inati, S. K., Brunel, N., & Zaghloul, K. A. (2019) · Science · doi:10.1126/science.aau8956 · Cited by 267 · see citing works
Reactivations of emotional memory in the hippocampus-amygdala system during sleep
Girardeau, G., Inema, I., & Buzsáki, G. (2017) · Nature Neuroscience · doi:10.1038/nn.4637 · Cited by 266 · see citing works
Jadhav, S. P., Rothschild, G., Roumis, D. K., & Frank, L. M. (2016) · Neuron · doi:10.1016/j.neuron.2016.02.010 · Cited by 250 · see citing works
Self-citationDorsal hippocampus contributes to model-based planning
Miller, K. J., Botvinick, M., & Brody, C. D. (2017) · Nature Neuroscience · doi:10.1038/nn.4613 · Cited by 243 · see citing works
A hippocampal network for spatial coding during immobility and sleep
Kay, K., Sosa, M., Chung, J. E., Karlsson, M. P., Larkin, M. C., & Frank, L. M. (2016) · Nature · doi:10.1038/nature17144 · Cited by 224 · see citing works
Internally generated sequences in learning and executing goal-directed behavior
Pezzulo, G., van der Meer, M. A. A., Lansink, C. S., & Pennartz, C. M. A. (2014) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2014.06.011 · Cited by 217 · see citing works
Hippocampal awake replay in fear memory retrieval
Wu, C.-T., Haggerty, D., Kemere, C., & Ji, D. (2017) · Nature Neuroscience · doi:10.1038/nn.4507 · Cited by 210 · see citing works
VTA neurons coordinate with the hippocampal reactivation of spatial experience
Gomperts, S. N., Kloosterman, F., & Wilson, M. A. (2015) · eLife · doi:10.7554/elife.05360 · Cited by 191 · see citing works
Superficial layers of the medial entorhinal cortex replay independently of the hippocampus
O’Neill, J., Boccara, C. N., Stella, F., Schoenenberger, P., & Csicsvari, J. (2017) · Science · doi:10.1126/science.aag2787 · Cited by 177 · see citing works
Exploring the role of context‐dependent hippocampal activity in spatial alternation behavior
Ainge, J. A., van der Meer, M. A. A., Langston, R. F., & Wood, E. R. (2007) · Hippocampus · doi:10.1002/hipo.20301 · Cited by 175 · see citing works
Coordinated grid and place cell replay during rest
Ólafsdóttir, H. F., Carpenter, F., & Barry, C. (2016) · Nature Neuroscience · doi:10.1038/nn.4291 · Cited by 175 · see citing works
The content of hippocampal “replay”
Pfeiffer, B. E. (2017) · Hippocampus · doi:10.1002/hipo.22824 · Cited by 172 · see citing works
Hippocampal-prefrontal reactivation during learning is stronger in awake compared with sleep states
Tang, W., Shin, J. D., Frank, L. M., & Jadhav, S. P. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.2291-17.2017 · Cited by 160 · see citing works
Self-citationOscillations and hippocampal–prefrontal synchrony
Gordon, J. A. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.02.012 · Cited by 159 · see citing works
Hippocampal Contributions to Model-Based Planning and Spatial Memory
Vikbladh, O. M., Meager, M. R., King, J. A., Blackmon, K., Devinsky, O., Shohamy, D., Burgess, N., & Daw, N. D. (2019) · Neuron · doi:10.1016/j.neuron.2019.02.014 · Cited by 152 · see citing works
Papale, A. E., Zielinski, M. C., Frank, L. M., Jadhav, S. P., & Redish, A. D. (2016) · Neuron · doi:10.1016/j.neuron.2016.10.028 · Cited by 139 · see citing works
Self-citationEmergence of preconfigured and plastic time-compressed sequences in early postnatal development
Farooq, U., & Dragoi, G. (2019) · Science · doi:10.1126/science.aav0502 · Cited by 131 · see citing works
Sequence learning and the role of the hippocampus in rodent navigation
Foster, D. J., & Knierim, J. J. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.12.005 · Cited by 124 · see citing works
Zielinski, M. C., Shin, J. D., & Jadhav, S. P. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0106-19.2019 · Cited by 123 · see citing works
Self-citationDiversity of sharp-wave–ripple LFP signatures reveals differentiated brain-wide dynamical events
Ramirez-Villegas, J. F., Logothetis, N., & Besserve, M. (2015) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1518257112 · Cited by 111 · see citing works
Hippocampal-cortical interaction in decision making
Yu, J. Y., & Frank, L. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.02.002 · Cited by 110 · see citing works
Hippocampal reactivation of random trajectories resembling brownian diffusion
Stella, F., Baracskay, P., O’Neill, J., & Csicsvari, J. (2019) · Neuron · doi:10.1016/j.neuron.2019.01.052 · Cited by 107 · see citing works
Xu, H., Baracskay, P., O’Neill, J., & Csicsvari, J. L. (2018) · Neuron · doi:10.1016/j.neuron.2018.11.015 · Cited by 105 · see citing works
Hippocampal Lesions Impair Rapid Learning of a Continuous Spatial Alternation Task
Kim, S. M., & Frank, L. M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005494 · Cited by 95 · see citing works
Zielinski, M. C., Tang, W., & Jadhav, S. P. (2017) · Hippocampus · doi:10.1002/hipo.22821 · Cited by 95 · see citing works
Self-citationLaminar organization of encoding and memory reactivation in the parietal cortex
Wilber, A. A., Skelin, I., Wu, W., & McNaughton, B. L. (2017) · Neuron · doi:10.1016/j.neuron.2017.08.033 · Cited by 95 · see citing works
Selection of preconfigured cell assemblies for representation of novel spatial experiences
Dragoi, G., & Tonegawa, S. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0522 · Cited by 94 · see citing works
Task Demands Predict a Dynamic Switch in the Content of Awake Hippocampal Replay
Ólafsdóttir, H., Carpenter, F., & Barry, C. (2017) · bioRxiv · doi:10.1016/j.neuron.2017.09.035 · Cited by 94 · see citing works
Sharp Wave Ripples during Visual Exploration in the Primate Hippocampus
Leonard, T. K., Mikkila, J. M., Eskandar, E., Gerrard, J., Kaping, D., Patel, S. R., Womelsdorf, T., & Hoffman, K. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0864-15.2015 · Cited by 80 · see citing works
Navratilova, Z., Hoang, L. T., Schwindel, C. D., Tatsuno, M., & McNaughton, B. L. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00006 · Cited by 78 · see citing works
Multiple modes of hippocampal–prefrontal interactions in memory-guided behavior
Shin, J. D., & Jadhav, S. P. (2016) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2016.07.015 · Cited by 77 · see citing works
Self-citationFarooq, U., Sibille, J., Liu, K., & Dragoi, G. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.040 · Cited by 73 · see citing works
Specific hippocampal representations are linked to generalized cortical representations in memory
Yu, J. Y., Liu, D. F., Loback, A., Grossrubatscher, I., & Frank, L. M. (2018) · Nature Communications · doi:10.1038/s41467-018-04498-w · Cited by 71 · see citing works
Middleton, S. J., Kneller Emily, M., Chen, S., Ogiwara, I., Montal, M., Yamakawa, K., & McHugh, T. J. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0163-8 · Cited by 67 · see citing works
Refinement of learned skilled movement representation in motor cortex deep output layer
Li, Q., Ko, H., Qian, Z., Yan, L. Y. C., Chan, D. C. W., Arbuthnott, G. W., Ke, Y., & Yung, W. (2017) · Nature Communications · doi:10.1038/ncomms15834 · Cited by 65 · see citing works
Memory Modulates Journey-Dependent Coding in the Rat Hippocampus
Ferbinteanu, J., Shirvalkar, P. R., & Shapiro, M. L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1241-11.2011 · Cited by 64 · see citing works
Tang, W., & Jadhav, S. P. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.01.002 · Cited by 62 · see citing works
Self-citationMashhoori, A., Hashemnia, S., McNaughton, B. L., Euston, D. R., & Gruber, A. J. (2018) · eLife · doi:10.7554/elife.29793 · Cited by 62 · see citing works
Sharp-Wave Ripples in Primates Are Enhanced near Remembered Visual Objects.
Leonard, T. K., & Hoffman, K. (2017) · Current Biology · doi:10.1016/j.cub.2016.11.027 · Cited by 61 · see citing works
Maharjan, D. M., Dai, Y., Glantz, E. H., & Jadhav, S. P. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.08.023 · Cited by 51 · see citing works
Self-citationGrid scale drives the scale and long-term stability of place maps
Mallory, C. S., Hardcastle, K., Bant, J. S., & Giocomo, L. M. (2018) · Nature Neuroscience · doi:10.1038/s41593-017-0055-3 · Cited by 46 · see citing works
"Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans": Correction.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.3.582 · Cited by 46 · see citing works
Planning at decision time and in the background during spatial navigation
Pezzulo, G., Donnarumma, F., Maisto, D., & Stoianov, I. P. (2019) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2019.04.009 · Cited by 44 · see citing works
Recurrent network model for learning goal-directed sequences through reverse replay
Haga, T., & Fukai, T. (2018) · eLife · doi:10.7554/elife.34171 · Cited by 43 · see citing works
Hippocampal replays under the scrutiny of reinforcement learning models
Cazé, R. D., Khamassi, M., Aubin, L., & Girard, B. (2018) · Journal of Neurophysiology · doi:10.1152/jn.00145.2018 · Cited by 38 · see citing works
Methodological Caveats in the Detection of Coordinated Replay between Place Cells and Grid Cells
Trimper, J. B., Trettel, S. G., Hwaun, E., & Colgin, L. L. (2017) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2017.00057 · Cited by 20 · see citing works
Analysis of learning deficits in aged rats on the W-track continuous spatial alternation task.
Kapellusch, A. J., Lester, A. W., Schwartz, B. A., Smith, A. C., & Barnes, C. A. (2018) · Behavioral Neuroscience · doi:10.1037/bne0000269 · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Sleep—A brain-state serving systems memory consolidation
Brodt, S., Inostroza, M., Niethard, N., & Born, J. (2023) · Neuron · doi:10.1016/j.neuron.2023.03.005 · Cited by 343 · see citing works
Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice
Gillespie, A. K., Maya, D. A., Denovellis, E. L., Liu, D. F., Kastner, D. B., Coulter, M. E., Roumis, D. K., Eden, U. T., & Frank, L. M. (2021) · Neuron · doi:10.1016/j.neuron.2021.07.029 · Cited by 192 · see citing works
Mechanisms of memory under stress
Schwabe, L., Hermans, E. J., Joëls, M., & Roozendaal, B. (2022) · Neuron · doi:10.1016/j.neuron.2022.02.020 · Cited by 188 · see citing works
Spatial goal coding in the hippocampal formation
Nyberg, N., Duvelle, É., Barry, C., & Spiers, H. J. (2022) · Neuron · doi:10.1016/j.neuron.2021.12.012 · Cited by 141 · see citing works
Sosa, M., & Giocomo, L. M. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00479-z · Cited by 142 · see citing works
Norman, Y., Raccah, O., Liu, S., Parvizi, J., & Malach, R. (2021) · Neuron · doi:10.1016/j.neuron.2021.06.020 · Cited by 140 · see citing works
Replay of behavioral sequences in the medial prefrontal cortex during rule switching
Kaefer, K., Nardin, M., Blahna, K., & Csicsvari, J. (2020) · Neuron · doi:10.1016/j.neuron.2020.01.015 · Cited by 120 · see citing works
The Versatile Wayfinder: Prefrontal Contributions to Spatial Navigation
Patai, E. Z., & Spiers, H. J. (2021) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2021.02.010 · Cited by 129 · see citing works
Associative and predictive hippocampal codes support memory-guided behaviors
Liu, C., Todorova, R., Tang, W., Oliva, A., & Fernández‐Ruiz, A. (2023) · Science · doi:10.1126/science.adi8237 · Cited by 143 · see citing works
Self-citationReplay, the default mode network and the cascaded memory systems model
Kaefer, K., Stella, F., McNaughton, B. L., & Battaglia, F. P. (2022) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00620-6 · Cited by 124 · see citing works
Multiple time-scales of decision-making in the hippocampus and prefrontal cortex
Tang, W., Shin, J. D., & Jadhav, S. P. (2021) · eLife · doi:10.7554/elife.66227 · Cited by 134 · see citing works
Self-citationSurget, A., & Belzung, C. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01136-8 · Cited by 122 · see citing works
Hippocampo-cortical circuits for selective memory encoding, routing, and replay
Harvey, R. E., Robinson, H. L., Liu, C., Oliva, A., & Fernandez-Ruiz, A. (2023) · Neuron · doi:10.1016/j.neuron.2023.04.015 · Cited by 101 · see citing works
Hippocampal replay of experience at real-world speeds
Denovellis, E. L., Gillespie, A. K., Coulter, M. E., Sosa, M., Chung, J. E., Eden, U. T., & Frank, L. M. (2021) · eLife · doi:10.7554/elife.64505 · Cited by 89 · see citing works
The Best Laid Plans: Computational Principles of Anterior Cingulate Cortex
Holroyd, C. B., & Verguts, T. (2021) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2021.01.008 · Cited by 84 · see citing works
Imagination as a fundamental function of the hippocampus
Comrie, A. E., Frank, L. M., & Kay, K. (2022) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2021.0336 · Cited by 84 · see citing works
Wittkuhn, L., & Schuck, N. W. (2021) · Nature Communications · doi:10.1038/s41467-021-21970-2 · Cited by 75 · see citing works
Chen, Q., Wu, J., Dong, X., Yin, H., Shi, X., Su, S., Che, B., Li, Y., & Yang, J. (2021) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2021.112152 · Cited by 69 · see citing works
Stoianov, I. P., Maisto, D., & Pezzulo, G. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2022.102329 · Cited by 68 · see citing works
Hippocampal place cell sequences differ during correct and error trials in a spatial memory task
Zheng, C., Hwaun, E., Loza, C. A., & Colgin, L. L. (2021) · Nature Communications · doi:10.1038/s41467-021-23765-x · Cited by 73 · see citing works
The evolving view of replay and its functions in wake and sleep
Findlay, G., Tononi, G., & Cirelli, C. (2020) · SLEEP Advances · doi:10.1093/sleepadvances/zpab002 · Cited by 61 · see citing works
Geometric transformation of cognitive maps for generalization across hippocampal-prefrontal circuits
Tang, W., Shin, J. D., & Jadhav, S. P. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112246 · Cited by 59 · see citing works
Self-citationBerners-Lee, A., Feng, T., Silva, D., Wu, X., Ambrose, E. R., Pfeiffer, B. E., & Foster, D. J. (2022) · Neuron · doi:10.1016/j.neuron.2022.03.010 · Cited by 57 · see citing works
Berners-Lee, A., Wu, X., & Foster, D. J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1158-20.2021 · Cited by 56 · see citing works
How our understanding of memory replay evolves
Chen, Z. S., & Wilson, M. A. (2023) · Journal of Neurophysiology · doi:10.1152/jn.00454.2022 · Cited by 65 · see citing works
Cortical reactivations predict future sensory responses
Nguyen, N. D., Lutas, A., Amsalem, O., Fernando, J., Ahn, A. Y.-E., Hakim, R., Vergara, J., McMahon, J., Dimidschstein, J., Sabatini, B. L., et al. (2023) · Nature · doi:10.1038/s41586-023-06810-1 · Cited by 53 · see citing works
Prefrontal–hippocampal interaction during the encoding of new memories
Takehara‐Nishiuchi, K. (2020) · Brain and Neuroscience Advances · doi:10.1177/2398212820925580 · Cited by 49 · see citing works
Wittkuhn, L., Chien, S., Hall-McMaster, S., & Schuck, N. W. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.08.002 · Cited by 47 · see citing works
Temporal context and latent state inference in the hippocampal splitter signal
Duvelle, É., Grieves, R. M., & van der Meer, M. A. A. (2022) · eLife · doi:10.7554/elife.82357 · Cited by 50 · see citing works
The role of experience in prioritizing hippocampal replay
Gorriz, M. H., Takigawa, M., & Bendor, D. (2023) · Nature Communications · doi:10.1038/s41467-023-43939-z · Cited by 51 · see citing works
Skipping ahead: A circuit for representing the past, present, and future
Robinson, J. C., & Brandon, M. P. (2021) · eLife · doi:10.7554/elife.68795 · Cited by 50 · see citing works
Symanski, C. A., Bladon, J. H., Kullberg, E. T., Miller, P. C., & Jadhav, S. P. (2022) · eLife · doi:10.7554/elife.79545 · Cited by 49 · see citing works
Self-citationThe predictive nature of spontaneous brain activity across scales and species
Dimakou, A., Pezzulo, G., Zangrossi, A., & Corbetta, M. (2025) · Neuron · doi:10.1016/j.neuron.2025.02.009 · Cited by 43 · see citing works
Multi-step planning in the brain
Miller, K. J., & Venditto, S. J. C. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.07.003 · Cited by 40 · see citing works
Distinct replay signatures for prospective decision-making and memory preservation
Wimmer, G. E., Liu, Y., McNamee, D., & Dolan, R. J. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2205211120 · Cited by 46 · see citing works
Inhibition allocates spikes during hippocampal ripples
Noguchi, A., Huszár, R., Morikawa, S., Buzsáki, G., & Ikegaya, Y. (2022) · Nature Communications · doi:10.1038/s41467-022-28890-9 · Cited by 35 · see citing works
Learning offline: memory replay in biological and artificial reinforcement learning
Roscow, E. L., Chua, R., Costa, R. P., Jones, M. W., & Lepora, N. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.07.007 · Cited by 36 · see citing works
Pfeiffer, B. E. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.2479-21.2022 · Cited by 36 · see citing works
Potential factors influencing replay across CA1 during sharp-wave ripples
de la Prida, L. M. (2020) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0236 · Cited by 36 · see citing works
Differential replay of reward and punishment paths predicts approach and avoidance
McFadyen, J., Liu, Y., & Dolan, R. J. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01287-7 · Cited by 34 · see citing works
A map of spatial navigation for neuroscience
Parra-Barrero, E., Vijayabaskaran, S., Seabrook, E., Wiskott, L., & Cheng, S. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105200 · Cited by 31 · see citing works
A large majority of awake hippocampal sharp-wave ripples feature spatial trajectories with momentum
Krause, E. L., & Drugowitsch, J. (2021) · Neuron · doi:10.1016/j.neuron.2021.11.014 · Cited by 33 · see citing works
The time course and organization of hippocampal replay
Mallory, C. S., Widloski, J., & Foster, D. J. (2025) · Science · doi:10.1126/science.ads4760 · Cited by 37 · see citing works
Backbone spiking sequence as a basis for preplay, replay, and default states in human cortex
Vaz, A. P., Wittig, J. H., Inati, S. K., & Zaghloul, K. A. (2023) · Nature Communications · doi:10.1038/s41467-023-40440-5 · Cited by 32 · see citing works
Incidence and prevalence of inflammatory bowel disease in Devon, UK
Hamilton, B., Green, H., Heerasing, N. M., Hendy, P. J., Moore, L., Chanchlani, N., Walker, G., Bewshea, C., Kennedy, N. A., Ahmad, T., et al. (2020) · Frontline Gastroenterology · doi:10.1136/flgastro-2019-101369 · Cited by 31 · see citing works
Beyond hippocampus: Thalamic and prefrontal contributions to an evolving memory
Yadav, N., Toader, A. C., & Rajasethupathy, P. (2024) · Neuron · doi:10.1016/j.neuron.2023.12.021 · Cited by 31 · see citing works
The generative grammar of the brain: a critique of internally generated representations
Dragoi, G. (2024) · Nature Reviews Neuroscience · doi:10.1038/s41583-023-00763-0 · Cited by 28 · see citing works
Neurons as will and representation
Fried, I. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00543-8 · Cited by 27 · see citing works
Sleep’s contribution to memory formation
Lutz, N. D., Harkotte, M., & Jan Born, A. (2025) · Physiological Reviews · doi:10.1152/physrev.00054.2024 · Cited by 40 · see citing works
Theta oscillations as a substrate for medial prefrontal-hippocampal assembly interactions
Nardin, M., Kaefer, K., Stella, F., & Csicsvari, J. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113015 · Cited by 27 · see citing works
Shin, J. D., & Jadhav, S. P. (2024) · Current Biology · doi:10.1016/j.cub.2024.05.018 · Cited by 29 · see citing works
Self-citationUrethane anesthesia suppresses hippocampal subthreshold activity and neuronal synchronization
Yagishita, H., Nishimura, Y., Noguchi, A., Shikano, Y., Ikegaya, Y., & Sasaki, T. (2020) · Brain Research · doi:10.1016/j.brainres.2020.147137 · Cited by 26 · see citing works
Wang, W., Liu, X., Yang, Z., Shen, H., Liu, L., Yu, Y. H., & Zhang, T. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.586321 · Cited by 23 · see citing works
Multiple-Timescale Representations of Space: Linking Memory to Navigation
Tang, W., & Jadhav, S. P. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-111020-084824 · Cited by 22 · see citing works
Self-citationLearning differentially shapes prefrontal and hippocampal activity during classical conditioning
Klee, J. L., Souza, B. C., & Battaglia, F. P. (2021) · eLife · doi:10.7554/elife.65456 · Cited by 22 · see citing works
Huang, P., Chen, X., Hu, X., Zhou, Q., Lin, L., Jiang, S., Fu, H. Q., Xiong, Y., Zeng, H., Fang, M., et al. (2020) · NeuroMolecular Medicine · doi:10.1007/s12017-020-08602-6 · Cited by 21 · see citing works
Prefrontal Synaptic Activation During Hippocampal Memory Reactivation
Nishimura, Y., Ikegaya, Y., & Sasaki, T. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.108885 · Cited by 21 · see citing works
MiR-29b-3p aggravates NG108-15 cell apoptosis triggered by fluorine combined with aluminum
Peng, Z., Yang, X., Zhang, H., Yin, M., Luo, Y., & Xie, C. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112658 · Cited by 20 · see citing works
Robinson, H. L., Todorova, R., Nagy, G. A., Gruzdeva, A., Paudel, P., Oliva, A., & Fernández-Ruiz, A. (2025) · Neuron · doi:10.1016/j.neuron.2025.10.003 · Cited by 27 · see citing works
Yu, J. Y., & Frank, L. M. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001393 · Cited by 19 · see citing works
Hippocampal replay sequence governed by spontaneous brain-wide dynamics
Yang, Y., Leopold, D. A., Duyn, J. H., & Liu, X. (2024) · PNAS Nexus · doi:10.1093/pnasnexus/pgae078 · Cited by 19 · see citing works
Pu, Z., Huang, H., Li, M., Li, H., Shen, X., Du, L., Wu, Q., Fang, X., Meng, X., Ni, Q., et al. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121130 · Cited by 17 · see citing works
Goal-directed hippocampal theta sweeps during memory-guided navigation
Tang, W., Mei, X., Harvey, R. E., Carbajal-Leon, E., Netzer, T., Chang, H., Oliva, A., & Fernández‐Ruiz, A. (2026) · Nature Neuroscience · doi:10.1038/s41593-026-02364-3 · Cited by 29 · see citing works
Self-citationSchmidt, B., & Redish, A. (2021) · Hippocampus · doi:10.1002/hipo.23367 · Cited by 16 · see citing works
Optimism and pessimism in optimised replay
Antonov, G. K., Gagne, C., Eldar, E., & Dayan, P. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009634 · Cited by 17 · see citing works
Takehara‐Nishiuchi, K., Morrissey, M. D., & Pilkiw, M. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1503-20.2020 · Cited by 17 · see citing works
Progress and issues in second-order analysis of hippocampal replay
van der Meer, M. A. A., Kemere, C. T., & Diba, K. (2020) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0238 · Cited by 16 · see citing works
Calvin, O. L., Erickson, M. T., Walters, C. J., & Redish, A. D. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3002954 · Cited by 25 · see citing works
Spatiotemporal Precision of Neuroimaging in Psychiatry
McFadyen, J., & Dolan, R. J. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.08.016 · Cited by 15 · see citing works
den Bakker, H., Dijck, M. V., Sun, J., & Kloosterman, F. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112959 · Cited by 20 · see citing works
Zhang, J., Ou, J., & Liu, Y. (2025) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-112723-024516 · Cited by 17 · see citing works
Inhibitory plasticity supports replay generalization in the hippocampus
Liao, Z., Terada, S., Raikov, I., Hadjiabadi, D. H., Szoboszlay, M., Soltész, I., & Losonczy, A. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01745-w · Cited by 14 · see citing works
Jeong, H., Namboodiri, V. M. K., Jung, M. W., & Andermann, M. L. (2023) · Current Biology · doi:10.1016/j.cub.2023.10.073 · Cited by 11 · see citing works
Deceuninck, L., & Kloosterman, F. (2024) · eLife · doi:10.7554/elife.84004 · Cited by 13 · see citing works
Wang, Y., Wang, X., Wang, L., Li, Z., Meng, S., Zhu, N., An, X., Wang, L., Yang, J., Zheng, C., et al. (2024) · Current Biology · doi:10.1016/j.cub.2024.03.032 · Cited by 16 · see citing works
Progress on the hippocampal circuits and functions based on sharp wave ripples
Xie, B., Zhen, Z., Guo, O., Li, H., Guo, M., & Zhen, J. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.110695 · Cited by 12 · see citing works
Babl, S. S., & Sigurdsson, T. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003140 · Cited by 12 · see citing works
Memory Alone Does Not Account for the Way Rats Learn a Simple Spatial Alternation Task
Kastner, D. B., Gillespie, A. K., Dayan, P., & Frank, L. M. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0972-20.2020 · Cited by 11 · see citing works
Kastner, D. B., Miller, E. A., Yang, Z., Roumis, D. K., Liu, D. F., Frank, L. M., & Dayan, P. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110708 · Cited by 9 · see citing works
Mahr, J. B., & Fischer, B. (2022) · Perspectives on Psychological Science · doi:10.1177/17456916221120425 · Cited by 10 · see citing works
Ding, M., Tomsick, P. L., Young, R. A., & Jadhav, S. P. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1670-24.2025 · Cited by 9 · see citing works
Self-citationNegrón-Oyarzo, I., Dib, T., Chacana-Véliz, L., Quilodrán, N. L., & Urrutia-Piñones, J. (2024) · Frontiers in Neural Circuits · doi:10.3389/fncir.2024.1286111 · Cited by 7 · see citing works
30th Annual Computational Neuroscience Meeting: CNS*2021–Meeting Abstracts
Arora, K., Zulfiqar, I., Schultheiss, H., Martino, F. D., Gulban, O. F., Lage‐Castellanos, A., & Moerel, M. (2021) · Journal of Computational Neuroscience · doi:10.1007/s10827-021-00801-9 · Cited by 9 · see citing works
Toward the biological model of the hippocampus as the successor representation agent
Lee, H. (2022) · Biosystems · doi:10.1016/j.biosystems.2022.104612 · Cited by 10 · see citing works
Kang, X., Wang, W., Zuo, Y., Wang, Y.-L., Zhang, L., & Liu, L.-X. (2024) · Journal of Stroke & Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2024.108101 · Cited by 8 · see citing works
Experience alters hippocampal and cortical network communication via a KIBRA-dependent mechanism
Quigley, L. D., Pendry, R., Mendoza, M. L., Pfeiffer, B. E., & Volk, L. J. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112662 · Cited by 8 · see citing works
Conjoint generalized and trajectory-specific coding of task structure by prefrontal neurons
Muysers, H., Bartos, M., & Sauer, J. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115420 · Cited by 9 · see citing works
Jarovi, J., Pilkiw, M., & Takehara‐Nishiuchi, K. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113492 · Cited by 8 · see citing works
Replay builds an efficient cognitive map offline to avoid computation onlinePreprint
Ou, J., Qu, Y., Xu, Y., Xiao, Z., Behrens, T. E. J., & Liu, Y. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.08.632067 · Cited by 13 · see citing works
A hippocampal population code for rapid generalizationPreprint
Tang, W., Chang, H., Liu, C., Perez-Hernandez, S., Zheng, W. Y., Park, J., Oliva, A., & Fernández‐Ruiz, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.15.643456 · Cited by 9 · see citing works
Self-citationShin, J. D., Tang, W., & Jadhav, S. P. (2023) · STAR Protocols · doi:10.1016/j.xpro.2023.102513 · Cited by 7 · see citing works
Self-citationHippocampal theta sequences in REM sleep during spatial learningPreprint
Zielinski, M. C., Shin, J. D., & Jadhav, S. P. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.15.439854 · Cited by 7 · see citing works
Self-citationKim, E. J., Park, S., Schuessler, B. P., Boo, H., Cho, J., & Kim, J. J. (2024) · bioRxiv · doi:10.1016/j.celrep.2025.116081 · Cited by 6 · see citing works
Background synaptic input modulates the visuospatial working memory
Wang, T., Sun, J., Yang, F., Li, J., Wang, W., & Liu, F. (2021) · Physical review. E · doi:10.1103/physreve.104.024416 · Cited by 6 · see citing works
Multi-Step Planning in the BrainPreprint
Miller, K. J., & Venditto, S. J. C. (2020) · doi:10.31234/osf.io/kv86m · Cited by 7 · see citing works
Poursiami, H., Moshruba, A., Cooper, K. W., Gobin, D., Kaiser, M. A.-A., Singh, A., Noor, R., Shahbaba, B., Jaiswal, A., Fortin, N. J., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-10586-x · Cited by 6 · see citing works
A unifying account of replay as context-driven memory reactivation
Zhou, Z., Kahana, M. J., & Schapiro, A. C. (2026) · eLife · doi:10.1101/2023.03.22.533833 · Cited by 6 · see citing works
Theta-encoded information flow from dorsal CA1 to prelimbic cortex drives memory reconsolidation
Radiske, A., González, M. C., Rossato, J. I., Conde‐Ocazionez, S., & Cammarota, M. (2025) · iScience · doi:10.1016/j.isci.2025.112821 · Cited by 5 · see citing works
Davydova, T. V., Алексеевна, Г. М., Кудрин, В. С., Наркевич, В. Б., Vetrilé, L. A., Ia, Z., & Sewell, R. D. E. (2020) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-020-04812-x · Cited by 5 · see citing works
Replay as a Basis for Backpropagation Through Time in the Brain
Cheng, H., & Brown, J. W. (2025) · Neural Computation · doi:10.1162/neco_a_01735 · Cited by 5 · see citing works
- Authors
- Shin, J. D., Tang, W., & Jadhav, S. P.
- Affiliations
- Brandeis University (US)
- Corresponding author
- Tang, Wenbo
- Jadhav, Shantanu P.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2019-12
- Volume
- 104
- Issue
- 6
- Pages
- 1110-1125.e7
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC6923537
- OpenAlex
- W2982510093
- Semantic Scholar
- 8ebb0bde31a27c8b9dcb6d2f6ceb5affb2cff1dc
- Cited by
- 199
- References
- 100
- Citations by year
- 2026: 25 · 2025: 47 · 2024: 22 · 2023: 25 · 2022: 23 · 2021: 32 · 2020: 23 · 2019: 2
- FWCI
- 11.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Whitehall Foundation
- Alfred P. Sloan Foundation
- National Institutes of Health
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- hippocampal replay, spatial learning, memory-guided decision-making, spatial working memory, place cells, prospective planning, retrospective evaluation, cognitive search, trajectory prediction
- MeSH terms
- Animals, Decision Making, Hippocampus, Male, Memory, Short-Term, Wakefulness, Prefrontal Cortex, Rats, Long-Evans, Rats, Spatial Learning
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
