The Application of Ferroptosis in Diseases

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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

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Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

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Glutathione Metabolism and Its Implications for Health

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

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Lung cancer: current therapies and new targeted treatments

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[44] Glutathione peroxidase

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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

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Targeting Ferroptosis to Iron Out Cancer

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Breast cancer

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Molecular mechanisms of necroptosis: an ordered cellular explosion

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The role of iron and reactive oxygen species in cell death

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Autophagy promotes ferroptosis by degradation of ferritin

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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

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Acute Lymphoblastic Leukemia in Children

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Ferroptosis as a target for protection against cardiomyopathy

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Regulation of glutathione synthesis

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Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

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Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

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Drugging the undruggable RAS: Mission Possible?

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Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

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Glutathione and its role in cellular functions

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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

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RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

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Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

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Hepcidin and iron homeostasis

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The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

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Huntington's disease: a clinical review

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Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling

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Identification of ACSL4 as a biomarker and contributor of ferroptosis

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Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

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Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

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[5] Diversity of glutathione peroxidases

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Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

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ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

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Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses

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The Roles of NRF2 in Modulating Cellular Iron Homeostasis

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FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

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Emerging Strategies of Cancer Therapy Based on Ferroptosis

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Iron‐sulphur clusters and the problem with oxygen

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Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

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Metallothionein‐1G facilitates sorafenib resistance through inhibition of ferroptosis

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RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer

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Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

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Inhibition of neuronal ferroptosis protects hemorrhagic brain

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Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC

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The release and activity of HMGB1 in ferroptosis

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T cell lipid peroxidation induces ferroptosis and prevents immunity to infection

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Characterization of ferroptosis in murine models of hemochromatosis

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Ironing out Ferroportin

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Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis

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Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

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Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

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Salinomycin kills cancer stem cells by sequestering iron in lysosomes

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Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

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HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

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Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

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Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

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Programmed cell death and the immune system

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Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

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Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

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Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis

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Lipid storage and lipophagy regulates ferroptosis

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Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation

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A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53

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DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin

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Ferroptosis and Its Role in Diverse Brain Diseases

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