The DOI matches its Crossref record; 65 of the 66 references it cites were found in a registry or an index.
Effects of intranasal oxytocin and vasopressin on cooperative behavior and associated brain activity in men
Open accessAbstract
The neural mechanisms supporting social bonds between adult men remain uncertain. In this double-blind, placebo-controlled study, we investigate the impact of intranasally administered oxytocin (OT) and vasopressin (AVP) on behavior and brain activity among men in the context of an iterated Prisoner's Dilemma game, which models a real-life social situation. fMRI results show that, relative to both AVP and placebo, OT increases the caudate nucleus response to reciprocated cooperation, which may augment the reward of reciprocated cooperation and/or facilitate learning that another person can be trusted. OT also enhances left amygdala activation in response to reciprocated cooperation. Behaviorally, OT was associated with increased rates of cooperation following unreciprocated cooperation in the previous round compared with AVP. AVP strongly increased cooperation in response to a cooperative gesture by the partner compared with both placebo and OT. In response to reciprocated cooperation, AVP increased activation in a region spanning known vasopressin circuitry implicated in affiliative behaviors in other species. Finally, both OT and AVP increase amygdala functional connectivity with the anterior insula relative to placebo, which may increase the amygdala's ability to elicit visceral somatic markers that guide decision making. These findings extend our knowledge of the neural and behavioral effects of OT and AVP to the context of genuine social interactions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“There are also human studies showing that the behavioral effects of AVP and OXT depend on social contextual factors (Declerck et al., 2010; Bartz et al., 2011; Rilling et al., 2012; Olff et al., 2013).”
From Sex-specific modulation of juvenile social play behavior by vasopressin and oxytocin depends on social context (2014) · cites this paper as Rilling et al., 2012
In the citing paper
“These data have, however, found OT and AVP can have differential effects on neural activity (i.e., BOLD fMRI responses) and cognition, at least in some cases although the effects of OT are more robust [84; 86; 87; 88; 89; 90].”
From Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery (2018) · cites this paper as [84]
In the citing paper
“It is clear, however, that peptides administered via the intranasal route produce significant alterations in cognition and neuronal activity whether they are acting peripherally and/or centrally.”
From Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery (2018) · cites this paper as [84]
In the citing paper
“The few studies that have compared the effects of intranasally administered OT and AVP in humans have reported that these peptides do not have opposing roles.”
From Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery (2018) · cites this paper as [84]
In the citing paper
“Indeed, other studies have also reported that OXT effects on amygdala responses often occur with concurrent changes in its connections with, and activation of, the insula (27 -29).”
From Oxytocin, the peptide that bonds the sexes also divides them (2016) · cites this paper as [27]
In the citing paper
“Although not statistically significant in a comparison between sex, OT lowered rates of cooperation with computer partners following defection in women only (Rilling et al., 2012; 2014).”
From Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior (2016) · cites this paper as Rilling et al., 2012
In the citing paper
“intranasal OT had opposite effects on brain activation during reciprocated cooperation in humans (Rilling et al., 2012; 2014)”
From Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior (2016) · cites this paper as Rilling et al., 2012
In the citing paper
“fMRI techniques are also not yet at a point where study subjects can be anything other than restrained during the examination (e.g., Bethlehem et al., 2012; Rilling et al., 2012), rendering them impractical for examining natural triggers or effects of oxytocin on animals and humans when engaged in contexts representative of natural social and environmental life.”
From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Rilling et al., 2012
In the citing paper
“For example, during an interpersonal cooperation task, Rilling et al (2012) found that OXT increased functional connectivity between the amygdala and the anterior insula.”
From Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder (2015) · cites this paper as Rilling et al, 2012
In the citing paper
“Rilling et al (2012) also found that OXT enhanced amygdala-insula functional connectivity and posited that this reflected an increased ability to assess internal states (eg, somatic markers) to guide decision-making.”
From Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder (2015) · cites this paper as Rilling et al (2012)
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Development and validation of brief measures of positive and negative affect: The PANAS scales.
Watson, D., Clark, L. A., & Tellegen, A. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.54.6.1063 · Cited by 32,433
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
How do you feel? Interoception: The sense of the physiological condition of the body
Craig, A. D. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn894 · Cited by 6,006
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406 · cited 1×
“The ventral anterior insula is involved in awareness of visceral feedback from the body thought to support subjective feeling states (Craig, 2002, 2004; Critchley et al., 2004).”
Forman, S. D., Cohen, J. D., Fitzgerald, M., Eddy, W. F., Mintun, M. A., & Noll, D. C. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910330508 · Cited by 3,202
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639
The neural correlates of maternal and romantic love
Bartels, A., & Zeki, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.11.003 · Cited by 1,497 · cited 1×
“…also appears to mediate female attachment to adult male partners in pair-bonding voles (Liu and Wang, 2003; Young et al, 2005) and possibly humans (Bartels and Zeki, 2004; Aron et al., 2005; Fisher et al., 2005), prompting the suggestion that modification of neural systems involved in maternal…”
A neural basis for social cooperation
Rilling, J. K., Gutman, D. A., Zeh, T. R., Pagnoni, G., Berns, G. S., & Kilts, C. D. (2002) · Neuron · doi:10.1016/s0896-6273(02)00755-9 · Cited by 1,451
Sniffing neuropeptides: A transnasal approach to the human brain
Born, J., Lange, T., Kern, W., McGregor, G. P., Bickel, U., & Fehm, H. L. (2002) · Nature Neuroscience · doi:10.1038/nn0602-849 · Cited by 1,356
Getting to Know You: Reputation and Trust in a Two-Person Economic Exchange
King-Casas, B., Tomlin, D., Anen, C., Camerer, C. F., Quartz, S. R., & Montague, P. R. (2005) · Science · doi:10.1126/science.1108062 · Cited by 1,345
Kurth, F., Zilles, K., Fox, P. T., Laird, A. R., & Eickhoff, S. B. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0255-z · Cited by 1,293
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.009 · Cited by 1,258
The Neuropeptide Oxytocin Regulates Parochial Altruism in Intergroup Conflict Among Humans
De Dreu, C. K. W., Greer, L. L., Handgraaf, M. J. J., Shalvi, S., Van Kleef, G. A., Baas, M., Ten Velden, F. S., Van Dijk, E., & Feith, S. W. W. (2010) · Science · doi:10.1126/science.1189047 · Cited by 1,148
The subgenual anterior cingulate cortex in mood disorders
Drevets, W. C., Savitz, J., & Trimble, M. (2008) · CNS Spectrums · doi:10.1017/s1092852900013754 · Cited by 1,109
Landgraf, R., & Neumann, I. D. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.05.001 · Cited by 1,059
Insel, T. R. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.005 · Cited by 1,044
A functional imaging study of cooperation in two-person reciprocal exchange
McCabe, K., Houser, D., Ryan, L., Smith, V., & Trouard, T. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211415698 · Cited by 984
Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love
Aron, A., Fisher, H., Mashek, D. J., Strong, G., Li, H., & Brown, L. L. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00838.2004 · Cited by 963
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders.
Andari, E., Duhamel, J.-R., Zalla, T., Herbrecht, E., Leboyer, M., & Sirigu, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910249107 · Cited by 941
Oxytocin and the Neural Mechanisms Regulating Social Cognition and Affiliative Behavior
Ross, H. E., & Young, L. J. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.004 · Cited by 856 · cited 2×
“, 2005), prompting the suggestion that modification of neural systems involved in maternal care is a parsimonious mechanism for the evolution of adult female pair-bonding (Ross and Young, 2009).”
Critchley, H. D., Elliott, R., Mathias, C. J., & Dolan, R. J. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-08-03033.2000 · Cited by 813
Vasopressin and Oxytocin Excite Distinct Neuronal Populations in the Central Amygdala
Huber, D., Veinante, P., & Stoop, R. (2005) · Science · doi:10.1126/science.1105636 · Cited by 804
Oxytocin, vasopressin, and human social behavior
Heinrichs, M., von Dawans, B., & Domes, G. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.005 · Cited by 799
Bohnet, I., & Zeckhauser, R. (2004) · Journal of Economic Behavior & Organization · doi:10.1016/j.jebo.2003.11.004 · Cited by 787
Fear and the brain: where have we been, and where are we going?
LeDoux, J. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00282-0 · Cited by 782
The Neuroscience of Social Decision-Making
Rilling, J. K., & Sanfey, A. G. (2011) · Annual Review of Psychology · doi:10.1146/annurev.psych.121208.131647 · Cited by 775
Oxytocin attenuates amygdala responses to emotional faces regardless of valence
Domes, G., Heinrichs, M., Gläscher, J., Büchel, C., Braus, D. F., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.025 · Cited by 774 · cited 3×
“Domes et al. (2007) also showed that OT decreased amygdala activation to all emotional face stimuli (including happy faces) in the right amygdala, and a recent study showed that OT increased amygdala activation to happy faces in the left amygdala (Gamer et al., 2010).”
Adult attachment predicts maternal brain and oxytocin response to infant cues.
Strathearn, L., Fonagy, P., Amico, J., & Montague, P. R. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.103 · Cited by 773
Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans
Hurlemann, R., Patin, A., Onur, O. A., Cohen, M. X., Baumgartner, T., Metzler, S., Dziobek, I., Gallinat, J., Wagner, M., Maier, W., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5538-09.2010 · Cited by 771
Perceptions of moral character modulate the neural systems of reward during the trust game
Delgado, M. R., Frank, R. H., & Phelps, E. A. (2005) · Nature Neuroscience · doi:10.1038/nn1575 · Cited by 729
Liu, Y., & Wang, Z. X. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00555-4 · Cited by 580 · cited 2×
“This mechanism also appears to mediate female attachment to adult male partners in pair-bonding voles (Liu and Wang, 2003; Young et al, 2005) and possibly humans (Bartels and Zeki, 2004; Aron et al., 2005; Fisher et al., 2005), prompting the suggestion that modification of neural systems involved…”
Neurobiology of fear responses: the role of the amygdala
Davis, M. (1997) · Journal of Neuropsychiatry · doi:10.1176/jnp.9.3.382 · Cited by 577
Topographic organization of projections from the amygdala to the visual cortex in the macaque monkey
Amaral, D. G., Behniea, H., & Kelly, J. L. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)01001-1 · Cited by 552
Effects of intranasal oxytocin on emotional face processing in women
Domes, G., Lischke, A., Berger, C., Grossmann, A., Hauenstein, K., Heinrichs, M., & Herpertz, S. C. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.06.016 · Cited by 521 · cited 3×
“Domes et al. (2010) reported a 34.2 pg/ ml increase at 45 min post-administration, whereas Andari et al. (2010) reported a 1.6 pg/ml increase 10 min postadministration.”
InfluentialSwain, J. E., Lorberbaum, J. P., Kose, S., & Strathearn, L. (2007) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2007.01731.x · Cited by 499
Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans
Gamer, M., Zurowski, B., & Büchel, C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000985107 · Cited by 487 · cited 10×
“OT appears to reduce the salience of negative social stimuli and increase the salience of positive social stimuli (Heinrichs et al., 2003; Baumgartner et al., 2008; Guastella et al., 2008; Petrovic et al., 2008; Unkelbach et al., 2008; Heinrichs et al., 2009; Theodoridou et al., 2009; Gamer et al., 2010).”
InfluentialHuman feelings: why are some more aware than others?
Craig, A. D. (. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.04.004 · Cited by 445
Oxytocin Attenuates Affective Evaluations of Conditioned Faces and Amygdala Activity
Petrovic, P., Kalisch, R., Singer, T., & Dolan, R. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4572-07.2008 · Cited by 424 · cited 4×
“…to reduce the salience of negative social stimuli and increase the salience of positive social stimuli (Heinrichs et al., 2003; Baumgartner et al., 2008; Guastella et al., 2008; Petrovic et al., 2008; Unkelbach et al., 2008; Heinrichs et al., 2009; Theodoridou et al., 2009; Gamer et al., 2010).”
InfluentialRomantic love: an fMRI study of a neural mechanism for mate choice.
Fisher, H., Aron, A., & Brown, L. L. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20772 · Cited by 396
Loup, F., Tribollet, E., Dubois-Dauphin, M., & Dreifuss, J. J. (1991) · Brain Research · doi:10.1016/0006-8993(91)90345-v · Cited by 378
Oxytocin enhances the encoding of positive social memories in humans.
Guastella, A. J., Mitchell, P. B., & Mathews, F. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.02.008 · Cited by 352
Dopaminergic-neuropeptide interactions in the social brain
Skuse, D. H., & Gallagher, L. (2009) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2008.09.007 · Cited by 340
Theodoridou, A., Rowe, A. C., Penton-Voak, I. S., & Rogers, P. J. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.03.019 · Cited by 318
Sex-specific influences of vasopressin on human social communication
Thompson, R. R., George, K., Walton, J. C., Orr, S. P., & Benson, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600406103 · Cited by 312
Characterization of the oxytocin system regulating affiliative behavior in female prairie voles
Ross, H. E., Cole, C. D., Smith, Y., Neumann, I. D., Landgraf, R., Murphy, A. Z., & Young, L. J. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.05.055 · Cited by 309
Opposing BOLD responses to reciprocated and unreciprocated altruism in putative reward pathways
Rilling, J. K., Sanfey, A. G., Aronson, J. A., Nystrom, L. E., & Cohen, J. D. (2004) · NeuroReport · doi:10.1097/00001756-200411150-00022 · Cited by 281
Self-citationNonapeptide mechanisms of social cognition, behavior and species-specific social systems
Goodson, J. L., & Thompson, R. R. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.08.020 · Cited by 261
Functional organization of the human anterior insular cortex
Mutschler, I., Wieckhorst, B., Kowalevski, S., Derix, J., Wentlandt, J., Schulze‐Bonhage, A., & Ball, T. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.03.101 · Cited by 238
Meyer‐Lindenberg, A., Kolachana, B. S., Gold, B., Olsh, A., Nicodemus, K. K., Mattay, V. S., Dean, M. C., & Weinberger, D. R. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.54 · Cited by 221
The effects of vasopressin on human facial responses related to social communication
Thompson, R. R., Gupta, S., Miller, K., Mills, S. D., & Orr, S. P. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(02)00133-6 · Cited by 184
The organization of midbrain projections to the ventral striatum in the primate
Lynd‐Balta, E., & Haber, S. N. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90181-3 · Cited by 169
Anatomy and neurochemistry of the pair bond
Young, L. J., Murphy Young, A. Z., & Hammock, E. A. D. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20771 · Cited by 163
Audigier, S., & Barberis, C. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb03794.x · Cited by 156
Reputation for reciprocity engages the brain reward center
Phan, K. L., Sripada, C. S., Angstadt, M., & McCabe, K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1008137107 · Cited by 152
Zink, C. F., Stein, J. L., Kempf, L., Hakimi, S., & Meyer‐Lindenberg, A. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4899-09.2010 · Cited by 134
Autoradiographic localization of D1 and D2 dopamine receptors in the human brain
Keyser, J. D., Claeys, A., Backer, J. D., Ebinger, G., Roels, F., & Vauquelin, G. (1988) · Neuroscience Letters · doi:10.1016/0304-3940(88)90758-6 · Cited by 127
Oxytocin selectively facilitates recognition of positive sex and relationship words.
Unkelbach, C., Guastella, A. J., & Forgas, J. P. (2008) · Psychological Science · doi:10.1111/j.1467-9280.2008.02206.x · Cited by 122
Social cognitive neural networks during in-group and out-group interactions
Rilling, J. K., Dagenais, J. E., Goldsmith, D. R., Glenn, A. L., & Pagnoni, G. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.03.044 · Cited by 117
Involvement of vasopressin in affective disorders
Surget, A., & Belzung, C. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.065 · Cited by 84
Derick, S., Cheng, L. L., Voirol, M. J., Stoev, S., Giacomini, M., Wo, N. C., Szeto, H. H., Ben Mimoun, M., Andres, M., Gaillard, R. C., et al. (2002) · Endocrinology · doi:10.1210/en.2002-220363 · Cited by 76
Responses to Conflict and Cooperation in Adolescents with Anxiety and Mood Disorders
Tone, E. B., Parrish, J. M., Nelson, E. E., Easter, J. S., Thorne, J. F., Rilling, J. K., Ernst, M., & Pine, D. S. (2007) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-007-9113-8 · Cited by 51
Flagged first, then by citations
1 of the 66 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The Social Salience Hypothesis of Oxytocin
Shamay-Tsoory, S. G., & Abu-Akel, A. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.07.020 · Cited by 904
Oxytocin pathways and the evolution of human behavior
Carter, C. S. (2014) · Annual Review of Psychology · doi:10.1146/annurev-psych-010213-115110 · Cited by 714
Dumais, K. M., & Veenema, A. H. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2015.04.003 · Cited by 520
“Intranasal VP increased activity in areas such as the striatum, basal forebrain, insula, amygdala, and hippocampus in men, but decreased or had no effect in women (Rilling et al., 2012; 2014).”
BackgroundInfluentialNerve growth factor: from the early discoveries to the potential clinical use
Aloe, L., Rocco, M. L., Bianchi, P., & Manni, L. (2012) · Journal of Translational Medicine · doi:10.1186/1479-5876-10-239 · Cited by 460
De Dreu, C. K. W. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.009 · Cited by 455
Metadata
- Authors
- Rilling, J. K., DeMarco, A. C., Hackett, P. D., Thompson, R., Ditzen, B., Patel, R., & Pagnoni, G.
- Affiliations
- Emory University (US)
- Bowdoin College (US)
- University of Modena and Reggio Emilia (IT)
- Corresponding author
- Rilling, James K.
- Venue
- Psychoneuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2012-04
- Volume
- 37
- Issue
- 4
- Pages
- 447-461
- ISSN
- 0306-4530 (ISSN-L)
- PMC
- PMC3251702
- OpenAlex
- W2098974252
- Cited by
- 303
- References
- 66
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 9 · 2023: 10 · 2022: 18 · 2021: 10 · 2020: 13 · 2019: 22 · 2018: 25 · 2017: 35 · 2016: 31 · 2015: 32 · 2014: 36 · 2013: 26 · 2012: 18
- FWCI
- 36.67
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychoneuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Funders
- National Institutes of Health (UL1TR000454)
- National Institute of Mental Health (R01MH084068)
- National Center for Advancing Translational Sciences
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Experimental Behavioral Economics Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- oxytocin, vasopressin, intranasal administration, cooperation, prisoner's dilemma, social bonding, caudate nucleus, amygdala, anterior insula, functional connectivity, trust, reward, affiliative behavior, men
- MeSH terms
- Administration, Intranasal, Adolescent, Arginine Vasopressin, Brain, Cooperative Behavior, Double-Blind Method, Game Theory, Humans, Magnetic Resonance Imaging, Male, Oxytocin, Young Adult, Functional Neuroimaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
