The cortical language circuit: from auditory perception to sentence comprehension
Abstract
Over the years, a large body of work on the brain basis of language comprehension has accumulated, paving the way for the formulation of a comprehensive model. The model proposed here describes the functional neuroanatomy of the different processing steps from auditory perception to comprehension as located in different gray matter brain regions. It also specifies the information flow between these regions, taking into account white matter fiber tract connections. Bottom-up, input-driven processes proceeding from the auditory cortex to the anterior superior temporal cortex and from there to the prefrontal cortex, as well as top-down, controlled and predictive processes from the prefrontal cortex back to the temporal cortex are proposed to constitute the cortical language circuit.
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These brain regions overlap with areas typically considered important in language, social communication, self-referential and social cognition, pain and emotion.
“These brain regions overlap with areas typically considered important in processes such as language, social communication, self-referential and social cognition, pain and emotion.35, 36, 37, 38, 39”
From Intranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women (2017) · cites this paper as [36]
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Brain Functional and Structural Predictors of Language Performance
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Self-citationA model for Social Communication And Language Evolution and Development (SCALED)
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Lack of selectivity for syntax relative to word meanings throughout the language network
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Syntactic processing is distributed across the language system
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Language is primarily a tool for communication rather than thought
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A lexical semantic hub for heteromodal naming in middle fusiform gyrus
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The core and beyond in the language-ready brain
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The cortical dynamics of speaking: present shortcomings and future avenues
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Language repetition and short-term memory: an integrative framework
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Wernicke’s area revisited: Parallel streams and word processing
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The “Narratives” fMRI dataset for evaluating models of naturalistic language comprehension
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The Neurobiological Grounding of Persistent Stuttering: from Structure to Function
Neef, N. E., Anwander, A., & Friederici, A. D. (2015) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-015-0579-4 · Cited by 146 · see citing works
Self-citationHenseler, I., Regenbrecht, F., & Obrig, H. (2014) · Brain · doi:10.1093/brain/awt374 · Cited by 143 · see citing works
Probabilistic atlas for the language network based on precision fMRI data from >800 individuals
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Rodd, J. M., Vitello, S., Woollams, A. M., & Adank, P. (2015) · Brain and Language · doi:10.1016/j.bandl.2014.11.012 · Cited by 142 · see citing works
Abboub, N., Thierry Nazzi, A., & Gervain, J. (2016) · Brain and Language · doi:10.1016/j.bandl.2016.08.002 · Cited by 145 · see citing works
Keitel, A., Ince, R. A. A., Groß, J., & Kayser, C. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.11.062 · Cited by 130 · see citing works
Fruchter, J., & Marantz, A. (2015) · Brain and Language · doi:10.1016/j.bandl.2015.03.001 · Cited by 125 · see citing works
Processing of emotional vocalizations in bilateral inferior frontal cortex
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Martin, A. E. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00120 · Cited by 124 · see citing works
Zaccarella, E., Schell, M., & Friederici, A. D. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.06.011 · Cited by 122 · see citing works
Self-citationCavelti, M., Kircher, T. T. J., Nagels, A., Strik, W. K., & Homan, P. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.02.051 · Cited by 121 · see citing works
Interhemispheric temporal lobe connectivity predicts language impairment in adolescents born preterm
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Krieg, S. M., Tarapore, P. E., Picht, T., Tanigawa, N., Houde, J. F., Sollmann, N., Meyer, B., Vajkoczy, P., Berger, M. S., Ringel, F. A., et al. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.06.016 · Cited by 110 · see citing works
Connections for auditory language in the human brain
Gierhan, S. M. E. (2013) · Brain and Language · doi:10.1016/j.bandl.2012.11.002 · Cited by 109 · see citing works
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Composition is the Core Driver of the Language-selective Network
Mollica, F., Diachek, E., Mineroff, Z., Kean, H., Siegelman, M., Piantadosi, S. T., Futrell, R., Qian, P., & Fedorenko, E. G. (2020) · Neurobiology of Language · doi:10.1162/nol_a_00005 · Cited by 108 · see citing works
Intranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women
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“These brain regions overlap with areas typically considered important in processes such as language, social-communication, self-referential and social cognition, pain, and emotion (Amodio and Frith, 2006; Hickok and Poeppel, 2007; Friederici, 2012; Wager et al., 2013; Yang et al., 2015).”
Schell, M., Zaccarella, E., & Friederici, A. D. (2017) · Cortex · doi:10.1016/j.cortex.2017.09.002 · Cited by 103 · see citing works
Self-citationThe cerebellum, internal models and prediction in ‘non-motor’ aspects of language: A critical review
Argyropoulos, G. P. D. (2015) · Brain and Language · doi:10.1016/j.bandl.2015.08.003 · Cited by 103 · see citing works
Agosta, F., Galantucci, S., Canu, E., Cappa, S. F., Magnani, G., Franceschi, M., Falini, A., Comı, G., & Filippi, M. (2013) · Brain and Language · doi:10.1016/j.bandl.2013.06.003 · Cited by 98 · see citing works
Cortical and structural‐connectivity damage correlated with impaired syntactic processing in aphasia
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Klingbeil, J., Wawrzyniak, M., Stockert, A., & Saur, D. (2017) · Brain and Cognition · doi:10.1016/j.bandc.2017.08.005 · Cited by 95 · see citing works
A 204-subject multimodal neuroimaging dataset to study language processing
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Automatic Semantic Facilitation in Anterior Temporal Cortex Revealed through Multimodal Neuroimaging
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Temporal scaling of neural responses to compressed and dilated natural speech
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Domain-General Brain Regions Do Not Track Linguistic Input as Closely as Language-Selective Regions
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Towards a Computational Comparative Neuroprimatology: Framing the language-ready brain
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Hierarchical functional connectivity between the core language system and the working memory system
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Self-citationBuilding words and phrases in the left temporal lobe
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The biological basis of language: insight from developmental grammatical impairments
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Neural correlates of fixation duration in natural reading: Evidence from fixation-related fMRI
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The emergence of hierarchical structure in human language
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“While neurobiology points to right-brained localization for human prosodic processing, it is well known that syntactic processing is localized to left-brain areas in humans, while “naming” involves both dorsal and ventral streams (Friederici, 2012).”
BackgroundNeural correlates of childhood language disorder: a systematic review
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Intrinsic Functional Connectivity in the Adult Brain and Success in Second-Language Learning
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A single dual-stream framework for syntactic computations in music and language
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The brain dynamics of linguistic computation
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Jeon, H., & Friederici, A. D. (2013) · Nature Communications · doi:10.1038/ncomms3041 · Cited by 76 · see citing works
Self-citationRegev, M., Simony, E., Lee, K. J., Tan, K. M., Chen, J., & Hasson, U. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy282 · Cited by 74 · see citing works
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Language in the brain at rest: new insights from resting state data and graph theoretical analysis
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No evidence for differences among language regions in their temporal receptive windows
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Syntax in language and music: what is the right level of comparison?
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Functional and structural syntax networks in aging
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Self-citationNeural dynamics of semantic composition
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Minimal Phrase Composition Revealed by Intracranial Recordings
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Language in Brains, Minds, and Machines
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Auditory Cortical Plasticity Drives Training-Induced Cognitive Changes in Schizophrenia
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Learning word order at birth: A NIRS study
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The newborn brain is sensitive to the communicative function of language
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Meta-analytic evidence for a novel hierarchical model of conceptual processing
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- Authors
- Friederici, A. D.
- Affiliations
- Max Planck Institute for Human Cognitive and Brain Sciences (DE)
- Corresponding author
- Friederici, Angela D.
- Venue
- Trends in Cognitive Sciences
- Publisher
- Elsevier BV
- Published
- 2012-05
- Volume
- 16
- Issue
- 5
- Pages
- 262-268
- ISSN
- 1364-6613 (ISSN-L)
- OpenAlex
- W2172056482
- Cited by
- 748
- References
- 77
- Citations by year
- 2026: 39 · 2025: 33 · 2024: 56 · 2023: 51 · 2022: 71 · 2021: 74 · 2020: 75 · 2019: 60 · 2018: 47 · 2017: 53 · 2016: 54 · 2015: 54 · 2014: 35 · 2013: 35 · 2012: 9
- FWCI
- 3.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Cognitive Sciences (publishedVersion)
- PubMed (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Social Sciences › Psychology › Developmental and Educational Psychology › Reading and Literacy Development
- Social Sciences › Psychology › Developmental and Educational Psychology › Language Development and Disorders
- Keywords
- sentence comprehension, auditory perception, functional neuroanatomy, auditory cortex, prefrontal cortex, white matter tracts, bottom-up processing, top-down processing, predictive processing
- MeSH terms
- Auditory Perception, Brain Mapping, Cerebral Cortex, Humans, Language, Models, Neurological, Nerve Net, Comprehension
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