Astrocytes and the regulation of cerebral blood flow

Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo

Wang, X., Lou, N., Xu, Q., Tian, G.-F., Peng, W. G., Han, X., Kang, J., Takano, T., & Nedergaard, M. (2006) · Nature Neuroscience · doi:10.1038/nn1703 · Cited by 685

Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury

Wilhelmsson, U., Bushong, E. A., Price, D. L., Smarr, B. L., Phung, V., Terada, M., Ellisman, M. H., & Pekny, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602841103 · Cited by 643

Signaling at the Gliovascular Interface

Simard, M., Arcuino, G., Takano, T., Liu, Q. S., & Nedergaard, M. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-27-09254.2003 · Cited by 586

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

Park, L., Zhou, P., Pitstick, R., Capone, C., Anrather, J., Norris, E. H., Younkin, L., Younkin, S., Carlson, G., McEwen, B. S., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711568105 · Cited by 332

Nox2-Derived Reactive Oxygen Species Mediate Neurovascular Dysregulation in the Aging Mouse Brain

Park, L., Anrather, J., Girouard, H., Zhou, P., & Iadecola, C. (2007) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600491 · Cited by 275

NADPH Oxidase-Derived Reactive Oxygen Species Mediate the Cerebrovascular Dysfunction Induced by the Amyloid β Peptide

Park, L., Anrather, J., Zhou, P., Frys, K., Pitstick, R., Younkin, S., Carlson, G. A., & Iadecola, C. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5207-04.2005 · Cited by 244

Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo

Winship, I. R., Plaa, N., & Murphy, T. H. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4801-06.2007 · Cited by 221

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease

Dreier, J. P. (2011) · Nature Medicine · doi:10.1038/nm.2333 · Cited by 1,132

Astrocyte reactivity and reactive astrogliosis: costs and benefits

Pekny, M., & Pekna, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00041.2013 · Cited by 934

The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution

Herculano‐Houzel, S. (2014) · Glia · doi:10.1002/glia.22683 · Cited by 731

Toll‐like receptor 4 is required for α‐synuclein dependent activation of microglia and astroglia

Fellner, L., Irschick, R., Schanda, K., Reindl, M., Klimaschewski, L., Poewe, W., Wenning, G. K., & Stefanova, N. (2013) · Glia · doi:10.1002/glia.22437 · Cited by 697

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

Rajkowska, G., & Stockmeier, C. (2013) · Current Drug Targets · doi:10.2174/13894501113149990156 · Cited by 603

Cholesterol metabolism in neurons and astrocytes

Pfrieger, F. W., & Ungerer, N. (2011) · Progress in Lipid Research · doi:10.1016/j.plipres.2011.06.002 · Cited by 500

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

Minter, M. R., Taylor, J. M., & Crack, P. J. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13411 · Cited by 451

Role of Astrocytes in Neurovascular Coupling

Petzold, G. C., & Murthy, V. N. (2011) · Neuron · doi:10.1016/j.neuron.2011.08.009 · Cited by 409

Reactive Astrogliosis after Spinal Cord Injury—Beneficial and Detrimental Effects

Karimi-Abdolrezaee, S., & Billakanti, R. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8287-4 · Cited by 331

The neurovascular unit in brain function and disease: The neurovascular unit function

Lecrux, C., & Hamel, E. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2011.02256.x · Cited by 251

The contribution of astrocytes to the neuroinflammatory response in multiple sclerosis and experimental autoimmune encephalomyelitis

Brambilla, R. (2019) · Acta Neuropathologica · doi:10.1007/s00401-019-01980-7 · Cited by 246

Cerebral Hemodynamics and Vascular Risk Factors: Setting the Stage for Alzheimer's Disease

de la Torre, J. C. (2012) · Journal of Alzheimer's Disease · doi:10.3233/jad-2012-120793 · Cited by 219

Beyond neurovascular coupling, role of astrocytes in the regulation of vascular tone

Filosa, J. A., Morrison, H. W., Iddings, J. A., Du, W., & Kim, K. J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.03.064 · Cited by 222

Coverage of Blood Vessels by Astrocytic Endfeet Is Reduced in Major Depressive Disorder

Rajkowska, G., Hughes, J., Stockmeier, C. A., Javier Miguel-Hidalgo, J., & Maciag, D. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.09.024 · Cited by 209

Retinal Macroglial Responses in Health and Disease

de Hoz, R., Rojas, B., Ramírez, A. I., Salazar, J. J., Gallego, B. I., Triviño, A., & Ramírez, J. M. (2016) · BioMed Research International · doi:10.1155/2016/2954721 · Cited by 187

Electrophysiological correlates of the BOLD signal for EEG-informed fMRI

Murta, T., Leite, M., Carmichael, D. W., Figueiredo, P., & Lemieux, L. (2015) · Human Brain Mapping · doi:10.1002/hbm.22623 · Cited by 165

Reactive glial cells: increased stiffness correlates with increased intermediate filament expression

Lu, Y., Iandiev, I., Hollborn, M., Körber, N., Ulbricht, E., Hirrlinger, P. G., Pannicke, T., Wei, E., Bringmann, A., Wolburg, H., et al. (2011) · The FASEB Journal · doi:10.1096/fj.10-163790 · Cited by 172

Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts

Fellner, L., Jellinger, K. A., Wenning, G. K., & Stefanova, N. (2011) · Acta Neuropathologica · doi:10.1007/s00401-011-0833-z · Cited by 162

Age-dependent rescue by simvastatin of Alzheimer’s disease cerebrovascular and memory deficits

Tong, X.-K., Lecrux, C., & Hamel, E. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0169-12.2012 · Cited by 160

EEG and functional ultrasound imaging in mobile rats

Sieu, L.-A., Bergel, A., Tiran, E., Deffieux, T., Pernot, M., Gennisson, J.-L., Tanter, M., & Cohen, I. (2015) · Nature Methods · doi:10.1038/nmeth.3506 · Cited by 158

Neurovascular function in Alzheimer's disease patients and experimental models

Nicolakakis, N., & Hamel, E. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.43 · Cited by 156

The physiology of developmental changes in BOLD functional imaging signals

Harris, J. J., Reynell, C., & Attwell, D. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.04.001 · Cited by 142

When astrocytes become harmful: Functional and inflammatory responses that contribute to Alzheimer's disease

Avila-Muñoz, E., & Arias, C. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.07.004 · Cited by 114

Astrocyte–neuron interplay in maladaptive plasticity.

Papa, M., De Luca, C., Petta, F., Alberghina, L., & Cirillo, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.01.010 · Cited by 104

Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome

Ocon, A. J., Medow, M. S., Taneja, I., Clarke, D., & Stewart, J. M. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00138.2009 · Cited by 105

Astrocytes protect oligodendrocyte precursor cells via MEK/ERK and PI3K/Akt signaling

Arai, K., & Lo, E. H. (2010) · Journal of Neuroscience Research · doi:10.1002/jnr.22256 · Cited by 101

Caffeine and the Control of Cerebral Hemodynamics

Pelligrino, D. A., Xu, H.-L., & Vetri, F. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-091261 · Cited by 93

Astrocyte mitochondria: Central players and potential therapeutic targets for neurodegenerative diseases and injury

Gollihue, J. L., & Norris, C. M. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101039 · Cited by 93

Fluoxetine Requires the Endfeet Protein Aquaporin-4 to Enhance Plasticity of Astrocyte Processes

Di Benedetto, B., Malik, V. A., Begum, S., Jablonowski, L., Gómez-González, G. B., Neumann, I. D., & Rupprecht, R. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00008 · Cited by 77

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

Brandon, J. A., Farmer, B. C., Williams, H. C., & Johnson, L. A. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00180 · Cited by 75

Nanomicellar formulation of coenzyme Q10 (Ubisol-Q10) effectively blocks ongoing neurodegeneration in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model: potential use as an adjuvant treatment in Parkinson's disease

Sikorska, M., Lanthier, P., Miller, H., Beyers, M., Sodja, C., Zurakowski, B., Gangaraju, S., Pandey, S., & Sandhu, J. K. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.03.032 · Cited by 70

Apolipoprotein E4 mediates insulin resistance-associated cerebrovascular dysfunction and the post-prandial response

Johnson, L. A., Torres, E. R., Weber Boutros, S., Patel, E., Akinyeke, T., Alkayed, N. J., & Raber, J. (2019) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17746186 · Cited by 56

Astrocytes, emerging stars of energy homeostasis

Camandola, S. (2018) · Cell Stress · doi:10.15698/cst2018.10.157 · Cited by 25

Evaluation of postmortem cerebrospinal fluid S100B protein and serotonin levels: comparison of suicidal versus nonsuicidal deaths in Konya, Turkey

Dogan, K. H., Unaldi, M., & Demirci, S. (2016) · Journal of Forensic Sciences · doi:10.1111/1556-4029.13124 · Cited by 18