Sperm morphology analysis (strict criteria) in male infertility is not a prognostic factor in intrauterine insemination with husband’s sperm
Open accessAbstract
Objective To assess the prognostic value of strict sperm morphology analysis in intrauterine insemination with husband's sperm (IUI) cycles performed because of male infertility. Design Prospective study. Setting Academic tertiary hospital. Patients Seventy-four consecutive couples subjected to 271 IUI cycles because of male infertility. Main outcome measure Strict morphology analysis 1 month before the beginning of IUI following the criteria of Kruger et al. Results Pregnancy and no pregnancy couples were similar regarding strict normal forms (2.85% +/- 2.07% versus 3.13% +/- 2.63%), slightly amorphous forms, and the morphology index (11.79 +/- 6.06 versus 12.04 +/- 7.13). Pregnancy rates (PRs) were similar when normal forms were 4% (35.7%). The PR, although higher in the group with morphology index > 10% (41.4%) than in the group 10% (50.0%) than in the group Conclusion Strict morphology analysis 1 month before the beginning of IUI is not a useful prognostic factor in IUI performed because of male infertility.
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Recent studies have called into question the predictive value of sperm morphology for pregnancy and the need to move directly to ICSI in those with teratozoospermia.
“Recent studies have called into question the predictive value of sperm morphology for pregnancy and the need to move directly to ICSI in those with teratozoospermia (Matorras et al., 1995;Karabinus & Gelety, 1997;Check et al., 2007;Deveneau et al., 2014).”
From Isolated abnormal strict morphology is not a contraindication for intrauterine insemination (2015) · cites this paper as Matorras et al., 1995
Studies examining sperm morphology and pregnancy outcomes following IUI and IVF have produced variable results.
“In the context of these aforementioned limitations, studies have been performed examining sperm morphology and pregnancy outcomes following IUI7891011 and IVF112131415161718 with variable results.”
From Men with a complete absence of normal sperm morphology exhibit high rates of success without assisted reproduction (2017) · cites this paper as [9]
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- Authors
- Matorras, R., Corcóstegui, B., Perez, C., Mandiola, M., Mendoza, R., & Rodríguez-Escudero, F. J.
- Affiliations
- Hospital de Cruces (ES)
- ORCID
- Matorras, Roberto
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 1995-03
- Volume
- 63
- Issue
- 3
- Pages
- 608-611
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2344957300
- Cited by
- 70
- References
- 18
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 1 · 2021: 2 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 4 · 2015: 4 · 2014: 2 · 2013: 6 · 2012: 1
- FWCI
- 4.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Health Professions › General Health Professions › Male Reproductive Health Studies
- Keywords
- sperm morphology, male infertility, intrauterine insemination, pregnancy rate, prognostic factors
- MeSH terms
- Adult, Age Factors, Endometriosis, Female, Humans, Infertility, Male, Insemination, Artificial, Homologous, Male, Predictive Value of Tests, Pregnancy, Prognosis, Prospective Studies, Spermatozoa, Treatment Outcome
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