The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Therapist-delivered internet psychotherapy for depression in primary care: a randomised controlled trial
Abstract
Background Despite strong evidence for its effectiveness, cognitive-behavioural therapy (CBT) remains difficult to access. Computerised programs have been developed to improve accessibility, but whether these interventions are responsive to individual needs is unknown. We investigated the effectiveness of CBT delivered online in real time by a therapist for patients with depression in primary care.Methods In this multicentre, randomised controlled trial, 297 individuals with a score of 14 or more on the Beck depression inventory (BDI) and a confirmed diagnosis of depression were recruited from 55 general practices in Bristol, London, and Warwickshire, UK. Participants were randomly assigned, by a computer-generated code, to online CBT in addition to usual care (intervention; n=149) or to usual care from their general practitioner while on an 8-month waiting list for online CBT (control; n=148). Participants, researchers involved in recruitment, and therapists were masked in advance to allocation. The primary outcome was recovery from depression (BDI score <10) at 4 months. Analysis was by intention to treat. This trial is registered, number ISRCTN 45444578.Findings 113 participants in the intervention group and 97 in the control group completed 4-month follow-up. 43 (38%) patients recovered from depression (BDI score <10) in the intervention group versus 23 (24%) in the control group at 4 months (odds ratio 2.39, 95% CI 1.23-4.67; p=0.011), and 46 (42%) versus 26 (26%) at 8 months (2.07, 1.11-3.87; p=0.023).Interpretation CBT seems to be effective when delivered online in real time by a therapist, with benefits maintained over 8 months. This method of delivery could broaden access to CBT.Funding BUPA Foundation.
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“while internet treatment can be presented in real time [35], most treatment applications will not require that the work is performed at a particular time, and this is an advantage for both patients and clinicians.”
From The promise and pitfalls of the internet for cognitive behavioral therapy (2010) · cites this paper as [35]
In the citing paper
“Psychotherapy has also been provided effectively and with reasonable effect sizes via instant messaging (12).”
From Behavioral Intervention Technologies: Evidence review and recommendations for future research in mental health (2013) · cites this paper as [12]
In the citing paper
“Internet-enabled CBT has been shown to be clinically effective for the treatment of depression16 and is currently deployed within IAPT.”
From Quantifying the association between psychotherapy content and clinical outcomes using deep learning (2020) · cites this paper as [16]
In the citing paper
“Ten therapist-delivered sessions of CBT over the internet were effective in reducing depression at 4 and 8 months (equivalent to our short-term measures).71”
In the citing paper
“The attrition rates in this study were equal or lower compared with several similar studies on guided Web-based interventions for depression with long-term follow-up assessments [67,73,74].”
From Long-Term Results of a Web-Based Guided Self-Help Intervention for Employees With Depressive Symptoms: Randomized Controlled Trial (2014) · cites this paper as [73]
In the citing paper
“However, despite similar delivery context and study design, there are important differences between the therapist-supported intervention in the study by Kessler et al. [28] and the nonguided intervention in the study by de Graaf et al. [19].”
From Internet-based psychological treatments for depression (2012) · cites this paper as [28]
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“In other cases support was manualized in its delivery, and at times adherence measures were employed to map the adequate delivery of such support (e.g. Kessler et al., 2009).”
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“Finally, there are real time chat-based Internet treatments in which no therapist time is saved (6).”
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“We also compared between-group effect sizes from 2 other RCTs that compared a Web-based human therapy intervention for depression with a waiting list [44,45].”
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Self-citationInternet-Delivered Psychological Treatments
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“2003), and examples exist of chat-based real-time Internet treatment (Kessler et al. 2009), which takes more therapist time and requires scheduling.”
BackgroundInternet-based psychological treatments for depression
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“WL + DG 42 Kessler et al. (2009) UK Phone and live Chat 1.”
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“Results Overall, we identified 103 published articles using MI during the study period (Figure 1) [32-134].”
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“36 Our other significant finding was that, despite the provision of a high level of telephone support, there was relatively low uptake of computerised CBT.”
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“One of the only larger-scale studies on real-time chat therapy was published in Lancet in 2009 (Kessler et al., 2009).”
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“…treatments for depression, such as e-mail therapy, in which the time spent by a clinician is not necessarily reduced in comparison with a face-to-face therapy, evidence suggests that they are about equally effective as low-intensity-guided interventions (Ruward et al., 2009; Kessler et al., 2009).”
BackgroundCurrent and Future Trends in Internet-Supported Mental Health Interventions
Barak, A., & Grohol, J. M. (2011) · Journal of Technology in Human Services · doi:10.1080/15228835.2011.616939 · Cited by 373
“A study by Kessler et al. (2009), for example, found effective outcomes for text-only chat intervention in treating depressive patients, using a CBT approach, without having any other contact with these patients.”
BackgroundCBT for depression: a pilot RCT comparing mobile phone vs. computer
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“Cognitive behavior therapy (CBT) has been shown to be effective in the treatment of depression [5,6].”
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“Three other trials were included that evaluated one intervention each: one trial with an intervention that combined components from acceptance and commitment therapy, behavioral activation, and mindfulness [38]; one with internet-delivered psychodynamic therapy (I-PDT) [31], and one with therapist-led I-CBT delivered…”
BackgroundHoermann, S., McCabe, K. L., Milne, D. N., & Calvo, R. A. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7023 · Cited by 263
“Studies S1-S14 [18-31] are described in Multimedia Appendix 3.”
Richardson, T., Stallard, P., & Velleman, S. (2010) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-010-0069-9 · Cited by 272
“…potential efficacy of computerised cognitive behaviour therapy (cCBT) in the treatment of a number of mental health problems, such as depression (Kessler et al. 2009; Warmerdam et al. 2010), anxiety/depression (Learmonth et al. 2008; Proudfoot et al. 2004), social phobia and social anxiety…”
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“These range from (1) the provision of evidencebased strategies as interactive self-help lessons; (2) e-mail, chat, or video-based sessions (27); (3) virtual reality for exposure interventions (28); (4) serious-games, in which psychological strategies are trained in the context of a computer game (29); (5) the use of a…”
BackgroundOnline Counseling: A Narrative and Critical Review of the Literature
Richards, D., & Viganò, N. (2013) · Journal of Clinical Psychology · doi:10.1002/jclp.21974 · Cited by 325
“Several randomized controlled trials that have included a treatment condition using synchronous or asynchronous online counseling have reported significant posttreatment and followup effects (Kessler et al., 2009; Vernmark et al., 2010), demonstrating the efficacy of delivering structured, online CBT treatments for de…”
BackgroundKretzschmar, K., Tyroll, H., Pavarini, G., Manzini, A., Singh, I., & NeurOx Young People’s Advisory Group (2019) · Biomedical Informatics Insights · doi:10.1177/1178222619829083 · Cited by 270
“7 Besides using evidence-based techniques and testing the efficacy of the apps, we find it important that the platform informs users about: (1) the theoretical approach that guides the service, be it cognitive behavioural, humanistic, psychodynamic, or others; (2) whether the bot has been empirically tested; (3) what…”
MethodJohansson, R., Sjöberg, E., Sjögren, M., Johnsson, E., Carlbring, P., Andersson, T., Rousseau, A., & Andersson, G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036905 · Cited by 268
“[8,35]).”
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“…and colleagues (2008) looked at psychotherapy delivered via a range of telepsychology modalities, including the Internet, and two individual RCTs assessed Internet-delivered text-based therapy for depression with TAU comparison groups (Kessler et al., 2009; Kramer, Conijn, Oijevaar, & Riper, 2014).”
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“Therefore, we followed protocols designed for either Internet- (Kessler et al., 2009) or telephonebased CBT (Simon, Ludman, & Rutter, 2009; Simon, Ludman, Tutty, Operskalski, & Von Korff, 2004) used previously in primary care patients.”
Self-citationFacilitated physical activity as a treatment for depressed adults: randomised controlled trial
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Self-citationInternet-Based Cognitive-Behavioral Therapy for Depression: Current Progress and Future Directions
Webb, C. A., Rosso, I. M., & Rauch, S. L. (2017) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000139 · Cited by 217
“phone calls from therapists or research assistants providing encouragement, support, and clarification of iCBT lesson content and homework;(19) text-based communication between clients and clinicians;(18) and, on the more time-intensive end of the support spectrum, providing online CBT via scheduled hourlong sessions.…”
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“Internet-delivered CBT for major depression has been tested in a number of trials, with varying outcomes from promising (Andersson et al., 2005; Christensen, Griffiths, & Jorm, 2004; Kessler et al., 2009; Meyer et al., 2009; Perini, Titov, * Corresponding author.”
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Nguyen, T., Phung, D., Dao, B., Venkatesh, S., & Berk, M. (2014) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2014.2315623 · Cited by 231
“Kessler et al. [14] examined if a cognitivebehavioral therapy (CBT) delivered online incorporated into usual care can improve the treatment of depression.”
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Validity of the Short Mood and Feelings Questionnaire in late adolescence
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“Much of this work has focused on the development and evaluation of computerized cognitive behavioral therapy (CBT) [5,8-13].”
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“Internet interventions may however also resemble traditional psychotherapy with scheduled sessions [4], but overall a characteristic feature is that that patients are reached from a distance and that therapist time is reduced compared with face-to-face treatment [5].”
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“…(Fukkink & Hermanns, 2009a); one that it was equivalent to a phone delivered service (Fukkink & Hermanns, 2009b); one that it was better than a wait-list control (Kessler et al., 2009); and one that it was effective but less so than a phone delivered service (King, Bambling, Reid et al., 2006).”
BackgroundInternet-delivered psychotherapy for depression in adults
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“…patients through a highly structured self-help programme, it is complicated to compare these results with traditional face-to-face CBT or Internet-delivered treatments that only consist of correspondence between therapist and patient, or even real-time online conversations (Kessler et al., 2009).”
BackgroundResultJohansson, R., Ekbladh, S., Hebert, A., Lindström, M., Möller, S., Petitt, E., Poysti, S., Larsson, M. H., Rousseau, A., Carlbring, P., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038021 · Cited by 167
“[23,24]).”
Effectiveness of Guided Internet-Based Cognitive Behavior Therapy in Regular Clinical Settings
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“ternet treatments, such as real-time chat [Kessler et al., 2009],”
Watkins, E. R., Taylor, R. S., Byng, R., Baeyens, C., Read, R., Pearson, K., & Watson, L. (2012) · Psychological Medicine · doi:10.1017/s0033291711002480 · Cited by 160
“…delivery systems include online computerized CBT programmes (Christensen et al. 2004), therapist-delivered internet CBT using instant messaging (Kessler et al. 2009) and guided self-help interventions (Gellatly et al. 2007), in which a trained worker supports the patient in implementing a…”
BackgroundTelemental health: A status update
Aboujaoude, E., Salame, W., & Naim, L. (2015) · World Psychiatry · doi:10.1002/wps.20218 · Cited by 154
“At the four-month follow-up, 38% of subjects in the real-time iCBT vs. 24% in the control group responded, based on the Beck Depression Inventory (11).”
BackgroundMethodAdvancing psychotherapy and evidence‐based psychological interventions
Emmelkamp, P. M. G., David, D., Beckers, T., Muris, P., Cuijpers, P. J., Lutz, W., Andersson, G., Araya, R., Rivera, R. M. B., Barkham, M., et al. (2013) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.1411 · Cited by 184
“First results of trials in this area are promising (Kessler et al., 2009), but more research is needed.”
BackgroundSelf-citationEffect of psychotherapy for depression on quality of life: meta-analysis
Kolovos, S., Kleiboer, A., & Cuijpers, P. (2016) · British Journal of Psychiatry · doi:10.1192/bjp.bp.115.175059 · Cited by 153
Online interventions for depression and anxiety – a systematic review
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“…De Graaf et al., 2009; Donker et al., 2013; Farrer, Christensen, Griffiths, &Mackinnon, 2011; Hollandare et al., 2011; Johansson et al., 2012, 2013; Kessler et al., 2009; Lintvedt et al., 2011; Meyer et al., 2009; O’Kearney et al., 2006; Perini, Titov, & Andrews, 2009; Ruwaard et al., 2009; Spek,…”
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“There have been mixed findings regarding the effectiveness of standard CBT in treatment of severe depression [29].”
ResultWiles, N. J., Thomas, L., Turner, N., Garfield, K., Kounali, D., Campbell, J., Kessler, D., Kuyken, W., Lewis, G., Morrison, J., et al. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00495-2 · Cited by 139
Self-citationFarrer, L., Christensen, H., Griffiths, K. M., & Mackinnon, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028099 · Cited by 140
“on the web have also delivered effective CBT to depressed samples [11], reduced depression in school settings [12] and in general practice environments [13,14], either with or without support from mental health professionals, paraprofessionals or teachers [11].”
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Cuijpers, P., Cristea, I. A., Ebert, D. D., Koot, H. M., Auerbach, R. P., Bruffaerts, R., & Kessler, R. C. (2016) · Depression and Anxiety · doi:10.1002/da.22461 · Cited by 137
“Recr Diagn Type Control Format Nsess RoB Countr Dimidjian et al.[16]—ba Comm Mood CBT other ind 16 3 US Dimidjian et al.[16]—ct Comm Mood BAT other ind 16 3 US Dowrick et al.[17]—cwd Comm Mood CBT cau grp 12 4 UK Dowrick et al.[17]—pst Comm Mood PST cau ind 6 4 UK Ekers et al.[18] Comm Mood BAT cau ind 12 4 UK Elkin e…”
BackgroundResultTowards a chatbot for digital counselling
Cameron, G., Cameron, D., Megaw, G., Bond, R., Mulvenna, M. D., O’Neill, S. M., Armour, C., & McTear, M. (2017) · Electronic workshops in computing · doi:10.14236/ewic/hci2017.24 · Cited by 142
“, (2009) evaluated the use of an online CBT intervention, however in their program it was not automated, but delivered on an individual basis by an online therapist [20].”
Guided internet-based CBT for common mental disorders
Andersson, G., Carlbring, P., Ljótsson, B., & Hedman, E. (2013) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-013-9237-9 · Cited by 119
“(Kessler et al. 2009).”
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Self-citationHollinghurst, S., Peters, T. J., Kaur, S., Wiles, N., Lewisand, G., & Kessler, D. (2010) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.073080 · Cited by 123
“This method of delivering CBT has been shown to be effective 11 and endorsed by Simon & Ludman, 29 but their commentary also highlights the importance of cost when using new communication technologies to deliver psychological therapy and here we show that the cost of providing online CBT represents…”
Self-citationFinegan, M., Firth, N., Wojnarowski, C., & Delgadillo, J. (2018) · Depression and Anxiety · doi:10.1002/da.22765 · Cited by 123
“These areDeRubeis et al. (2005), Elkin et al. (1989), Kessler et al. (2009), Knekt et al. (2008), Leichsenring et al. (2013), Roy-Byrne et al. (2010), and Talbot et al. (2011). bIncludes random sequence generation and allocation concealment.”
BackgroundOnline/Cyber Counseling Services in the COVID-19 Outbreak: Are They Really New?
Situmorang, D. D. B. (2020) · Journal of Pastoral Care & Counseling Advancing theory and professional practice through scholarly and reflective publications · doi:10.1177/1542305020948170 · Cited by 137
“Textbased communication creates a composed record that possibly benefits both counselees/clients and pastoral/spiritual counselors or psychologists (Kessler et al., 2009), and Goss and Anthony (2004) found that counselees/clients had improved control of the treatment session since they are able to…”
BackgroundInfluentialThe promise and pitfalls of the internet for cognitive behavioral therapy
Andersson, G. (2010) · BMC Medicine · doi:10.1186/1741-7015-8-82 · Cited by 114
“Second, while internet treatment can be presented in real time [35], most treatment applications will not require that the work is performed at a particular time, and this is an advantage for both patients and clinicians.”
BackgroundTwomey, C., O’Reilly, G., & Byrne, M. (2015) · Family Practice · doi:10.1093/fampra/cmu060 · Cited by 123
Pugh, N. E., Hadjistavropoulos, H. D., & Dirkse, D. (2016) · PLOS ONE · doi:10.1371/journal.pone.0149186 · Cited by 114
Quantifying the association between psychotherapy content and clinical outcomes using deep learning
Ewbank, M. P., Cummins, R., Tablan, V., Bateup, S., Catarino, A., Martin, A. J., & Blackwell, A. D. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.2664 · Cited by 108
Stallard, P., Richardson, T., Velleman, S., & Attwood, M. (2011) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s135246581000086x · Cited by 118
“…British Association for Behavioural and Cognitive Psychotherapies 2011 In adults, a number of studies (Bergstrom et al., 2008; Craske et al., 2009; Kessler et al., 2009; Learmonth, Trosh, Rai, Sewell and Cavanagh, 2008; Titov, Andrews, Schwencke, Drobny and Einstein, 2008; Warmerdam, van…”
BackgroundZhang, A., Borhneimer, L. A., Weaver, A., Franklin, C., Hai, A. H., Guz, S., & Li, S. (2019) · Journal of Behavioral Medicine · doi:10.1007/s10865-019-00046-z · Cited by 135
“…the British Association for Behavioural and cognitive Psychotherapies Individual sessions up to 10 sessions, other information NR DSM- IV(SCID) HADS-A HAM-A STAI Combined, anxiety and bipolar Kessler et al. (2009) T = 149 C = 148 34.9 years old, 32% male, Race NR TAU Psychologists trained in CBT.”
BackgroundInfluentialMassoudi, B., Holvast, F., Bockting, C. L. H., Burger, H., & Blanker, M. H. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.11.050 · Cited by 101
Are People With Chronic Diseases Interested in Using Telehealth? A Cross-Sectional Postal Survey
Edwards, L., Thomas, C., Gregory, A. C., Yardley, L., O’Cathain, A., Montgomery, A. A., & Salisbury, C. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3257 · Cited by 117
“For example, blood pressure self-monitoring, combined with self-titration of antihypertensive medication resulted in significant reductions in systolic blood pressure compared to usual care [12], while a therapist-delivered online cognitive behavioral therapy program led to greater recovery from depression than usual…”
BackgroundResultBird, T., Mansell, W., Wright, J., Gaffney, H., & Tai, S. (2018) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465817000820 · Cited by 109
“The amount of support can vary, with some programs requiring as little as one short email per week per client, while others delivered in ‘real-time’ require as much therapist time as face-to-face treatment (Kessler et al., 2009).”
BackgroundHolländare, F., Johnsson, S., Randestad, M., Tillfors, M., Carlbring, P., Andersson, G., & Engström, I. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01698.x · Cited by 111
“A cut-off of 10 has previously been used in depression treatment trials (40, 41) and was in one psychometric study (38) found to yield a high sensitivity for detecting depression.”
MethodRobinson, J., Hetrick, S., Cox, G., Bendall, S., Yuen, H. P., Yung, A., & Pirkis, J. (2016) · Early Intervention in Psychiatry · doi:10.1111/eip.12137 · Cited by 108
Buckman, J. E. J., Saunders, R., Stott, J. C. H., Arundell, L.-L., O’Driscoll, C., Davies, M. R., Eley, T. C., Hollon, S. D., Kendrick, T., Ambler, G., et al. (2021) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796021000342 · Cited by 114
“IPCRESS (Kessler et al., 2009) 295 Adults scoring ⩾14 BDI-II and GP confirmed diagnosis of depression 34.”
InfluentialSelf-citationKoenig, H. G., Pearce, M., Nelson, B., Shaw, S. F., Robins, C. J., Daher, N. S., Cohen, H. J., Berk, L., Bellinger, D. L., Pargäment, K. I., et al. (2015) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000273 · Cited by 126
“Not surprisingly, psychological approaches such as CBT have been particularly effective in treating depression in medical patients who need help addressing maladaptive beliefs about their illness that initiate and maintain depression (Bower et al., 2000; Kessler et al., 2009; Serfaty et al., 2009; Ward et al., 2000).”
BackgroundInfluentialSelf-citationCognitive behaviour therapy for depression in primary care: systematic review and meta-analysis
Santoft, F., Axelsson, E., Öst, L.-G., Hedman-Lagerlöf, M., Fust, J., & Hedman-Lagerlöf, E. (2019) · Psychological Medicine · doi:10.1017/s0033291718004208 · Cited by 105
“…Dalgard, 2006; Smit et al., 2006; González González et al., 2007; Spek et al., 2007; Laidlaw et al., 2008; Lovell et al., 2008; Wiles et al., 2008; Kessler et al., 2009; Serfaty et al., 2009; Hegerl et al., 2010; Naylor et al., 2010; Cramer et al., 2011; Dwight-Johnson et al., 2011; Ekers et al.,…”
Effectiveness of cognitive behavioural therapy in primary health care: a review.
Høifødt, R., Strøm, C., Kolstrup, N., Eisemann, M., & Waterloo, K. (2011) · Family Practice · doi:10.1093/fampra/cmr017 · Cited by 101
Urech, C., Grossert, A., Alder, J., Scherer, S., Handschin, B., Kasenda, B., Borislavova, B., Degen, S., Erb, J., Faessler, A., et al. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2017.74.8491 · Cited by 98
Using Telehealth to Provide Interventions for Children with ASD: a Systematic Review
de Nocker, Y. L., & Toolan, C. K. (2021) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-021-00278-3 · Cited by 114
Socioeconomic Indicators of Treatment Prognosis for Adults With Depression
Buckman, J. E. J., Saunders, R., Stott, J. C. H., Cohen, Z. D., Arundell, L.-L., Eley, T. C., Hollon, S. D., Kendrick, T., Ambler, G., Watkins, E. R., et al. (2022) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2022.0100 · Cited by 110
Self-citationSharp, D., Chew-Graham, C. A., Tylee, A. T., Lewis, G., Howard, L. M., Anderson, I. M., Abel, K. M., Turner, K. M., Hollinghurst, S., Tallon, D., et al. (2010) · Health Technology Assessment · doi:10.3310/hta14430 · Cited by 97
Self-citation(Inter)personal Computing: The Role of the Therapeutic Relationship in E-mental Health
Cavanagh, K., & Millings, A. (2013) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-013-9242-z · Cited by 88
“…using email, or message boards) for approximately the same amount of time in communication as in traditional face-to-face therapies, have also been demonstrated to be effective and cost-effective in a number of well-designed treatment studies (e.g. Hollinghurst et al. 2010; Kessler et al. 2009).”
BackgroundMethodKooistra, L. C., Wiersma, J. E., Ruwaard, J., Neijenhuijs, K., Lokkerbol, J., van Oppen, P., Smit, F., & Riper, H. (2019) · Journal of Medical Internet Research · doi:10.2196/14261 · Cited by 84
Outcomes of Integrated Behavioral Health with Primary Care
Balasubramanian, B. A., Cohen, D. J., Jetelina, K. K., Dickinson, L. M., Davis, M. M., Gunn, R., Gowen, L. K., deGruy, F. V., Miller, B. F., & Green, L. A. (2017) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2017.02.160234 · Cited by 93
Matsumoto, K., Sutoh, C., Asano, K., Seki, Y., Urao, Y., Yokoo, M., Takanashi, R., Yoshida, T., Tanaka, M., Noguchi, R., et al. (2018) · Journal of Medical Internet Research · doi:10.2196/12091 · Cited by 83
Littlewood, E., Duarte, A., Hewitt, C. E., Knowles, S. E., Palmer, S., Walker, S., Andersen, P., Araya, R., Barkham, M., Bower, P., et al. (2015) · Health Technology Assessment · doi:10.3310/hta191010 · Cited by 92
Self-citationGeraedts, A. S., Kleiboer, A. M., Twisk, J., Wiezer, N. M., van Mechelen, W., & Cuijpers, P. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3539 · Cited by 89
“The attrition rates in this study were equal or lower compared with several similar studies on guided Web-based interventions for depression with long-term follow-up assessments [67,73,74].”
A Roadmap to Computer-Based Psychotherapy in the United States
Cartreine, J. A., Ahern, D. K., & Locke, S. E. (2010) · Harvard Review of Psychiatry · doi:10.3109/10673221003707702 · Cited by 99
“A recent, large, randomized clinical trial of Internet distance therapy for depression by Kessler and colleagues 44 ( n = 297) compared treatment as usual in primary care augmented with ten sessions of CBT administered via instant messaging text (no voice) to treatment as usual in primary care.”
BackgroundInfluentialMental health related Internet use among psychiatric patients: a cross-sectional analysis
Kalckreuth, S., Trefflich, F., & Rummel-Kluge, C. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0368-7 · Cited by 86
“So far, promising results have been shown for the effective web-based treatment of many common psychiatric disorders [10,11] particularly for depression [12-21] and anxiety disorders [22-24].”
BackgroundModelo médico hegemónico: tendencias posibles y tendencias más o menos imaginarias
Menéndez, E. L. (2020) · Salud Colectiva · doi:10.18294/sc.2020.2615 · Cited by 84
“Uno de los campos donde la telemedicina ha tenido mayor desarrollo es el del diagnóstico y tratamiento online de padecimientos mentales, especialmente la depresión, que ha demostrado ser eficaz según un estudio publicado en The Lancet(22).”
BackgroundKooistra, L. C., Wiersma, J. E., Ruwaard, J., van Oppen, P., Smit, F., Lokkerbol, J., Cuijpers, P., & Riper, H. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0290-z · Cited by 82
“Most studies focused on evaluating clinical outcomes where online CBT is provided in addition to care-as-usual, either by a GP in primary care [25-27] or by mental health care providers in primary and secondary care settings [28].”
BackgroundZhang, A., Franklin, C., Jing, S., Bornheimer, L. A., Hai, A. H., Himle, J. A., Kong, D., & Ji, Q. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.12.008 · Cited by 89
Bennion, M. R., Hardy, G. E., Moore, R. K., Kellett, S., & Millings, A. (2020) · Journal of Medical Internet Research · doi:10.2196/16794 · Cited by 68
“The developers of psychological interventions have harnessed the internet as a delivery medium to enable increased access to evidence-based psychological therapies [1,2].”
BackgroundPickersgill, M. D. (2018) · Sociology of Health & Illness · doi:10.1111/1467-9566.12811 · Cited by 74
“…inscribed (Akrich 1992) with this logic of access; intervention trials, for instance, commonly note the utility of the technology in terms of enhancing admission into therapy for those who might otherwise be excluded from care (e.g. Kessler et al. 2009, Nelson et al. 2003, O ’ Reilly et al. 2007).”
BackgroundHassiotis, A., Serfaty, M. A., Azam, K., Strydom, A., Blizard, R., Romeo, R., Martin, S., & King, M. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.05.076 · Cited by 80
Self-citationCounselling for mental health and psychosocial problems in primary care
Bower, P., Knowles, S. E., Coventry, P. A., & Rowland, N. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001025.pub3 · Cited by 83
Ahern, E., Kinsella, S., & Semkovska, M. (2017) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2018.1407245 · Cited by 75
“interactive videos [43], as well as online, synchronous chatbased technology [50].”
BackgroundMethodPsychodynamic Treatment, Training, and Supervision Using Internet-Based Technologies
Fishkin, R. E., Fishkin, L. P., Leli, U., Katz, B., & Snyder, E. W. (2011) · Journal of the American Academy of Psychoanalysis and Dynamic Psychiatry · doi:10.1521/jaap.2011.39.1.155 · Cited by 71
Chalder, M., Wiles, N., Campbell, J., Hollinghurst, S., Searle, A., Haase, A., Taylor, A., Fox, K., Baxter, H., Davis, M., et al. (2012) · Health Technology Assessment · doi:10.3310/hta16100 · Cited by 71
Self-citation
Metadata
- Authors
- Kessler, D., Lewis, G., Kaur, S., Wiles, N., King, M., Weich, S., Sharp, D. J., Araya, R., Hollinghurst, S., & Peters, T. J.
- Affiliations
- National Institute for Health and Care Research (GB)
- University of Bristol (GB)
- The Royal Free Hospital (GB)
- University of Warwick (GB)
- Corresponding author
- Kessler, David
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2009-08
- Volume
- 374
- Issue
- 9690
- Pages
- 628-634
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2130951278
- Cited by
- 387
- References
- 22
- Citations by year
- 2026: 9 · 2025: 7 · 2024: 12 · 2023: 10 · 2022: 12 · 2021: 19 · 2020: 30 · 2019: 23 · 2018: 26 · 2017: 29 · 2016: 33 · 2015: 28 · 2014: 41 · 2013: 35 · 2012: 27
- FWCI
- 28.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Bristol Research (University of Bristol) (submittedVersion)
- Explore Bristol Research (submittedVersion)
- Funders
- National Institute for Health and Care Research (CL-2007-25-001)
- Bupa Foundation
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- online therapy, cognitive behavioral therapy, depression, primary care, access to mental health care, recovery from depression
- MeSH terms
- Adult, Antidepressive Agents, Depressive Disorder, England, Female, Follow-Up Studies, Health Services Accessibility, Humans, Male, Psychiatric Status Rating Scales, Severity of Illness Index, Therapy, Computer-Assisted, Cognitive Behavioral Therapy, Effect Modifier, Epidemiologic, Linear Models, Logistic Models, Treatment Outcome, Internet, International Classification of Diseases
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