The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Double dissociation of function within the hippocampus: A comparison of dorsal, ventral, and complete hippocampal cytotoxic lesions
Abstract
Rats with complete cytotoxic hippocampal lesions exhibited spatial memory impairments in both the water maze and elevated T maze. They were hyperactive in photocell cages; swam faster in the water maze; and were less efficient on a nonspatial, differential reinforcement of low rates (DRL) task. Performance on both spatial tasks was also impaired by selective dorsal but not ventral lesions; swim speed was increased by ventral but not dorsal lesions. Both partial lesions caused a comparable reduction in DRL efficiency, although these effects were smaller than those of complete lesions. Neither partial lesion induced hyperactivity when rats were tested in photocell cages, although both complete and ventral lesion groups showed increased activity after footshock in other studies (Richmond et al., 1999). These results demonstrate possible functional dissociations along the septotemporal axis of the hippocampus.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“bilateral lesions of this area have been shown to reduce anxiety-like behavior in rodents (13–15)”
From Perineuronal nets, inhibitory interneurons and anxiety-related ventral hippocampal neuronal oscillations are altered by early life adversity (2019) · cites this paper as [13]
Citations
Cites
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010
Developments of a water-maze procedure for studying spatial learning in the rat
Morris, R. (1984) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(84)90007-4 · Cited by 7,180
Spatial localization does not require the presence of local cues
Morris, R. G. M. (1981) · Learning and Motivation · doi:10.1016/0023-9690(81)90020-5 · Cited by 2,699
Modality-Specific Retrograde Amnesia of Fear
Kim, J. J., & Fanselow, M. S. (1992) · Science · doi:10.1126/science.1585183 · Cited by 2,483
Hippocampus, space, and memory
Olton, D. S., Becker, J. T., & Handelmann, G. E. (1979) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00062713 · Cited by 2,018
JACOBSON, L., & SAPOLSKY, R. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-2-118 · Cited by 1,739
On the role of the hippocampus in learning and memory in the rat.
Jarrard, L. E. (1993) · Behavioral and Neural Biology · doi:10.1016/0163-1047(93)90664-4 · Cited by 1,125
Brog, J. S., Salyapongse, A., Deutch, A. Y., & Zahm, D. S. (1993) · Journal of Comparative Neurology · doi:10.1002/cne.903380209 · Cited by 1,102
The hippocampus and contextual retrieval of information from memory: A theory
Hirsh, R. (1974) · Behavioral Biology · doi:10.1016/s0091-6773(74)92231-7 · Cited by 957
Moser, E., Moser, M. ‐., & Andersen, P. N. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-09-03916.1993 · Cited by 953
Spatial learning with a minislab in the dorsal hippocampus.
Moser, M., Moser, E. I., Forrest, E., Andersen, P. N., & Morris, R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.21.9697 · Cited by 944
Groenewegen, H. J., Vermeulen‐Vanderzee, E., Kortschot, A. T., & Witter, M. P. (1987) · Neuroscience · doi:10.1016/0306-4522(87)90275-2 · Cited by 867
The hippocampus—what does it do?
Eichenbaum, H., Otto, T., & Cohen, N. J. (1992) · Behavioral and Neural Biology · doi:10.1016/0163-1047(92)90724-i · Cited by 867
Comparison of spatial firing characteristics of units in dorsal and ventral hippocampus of the rat
Jung, M. W., Wiener, S. I., & McNaughton, B. L. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-12-07347.1994 · Cited by 844
Conservation of hippocampal memory function in rats and humans
Bunsey, M. D., & Eichenbaum, H. (1996) · Nature · doi:10.1038/379255a0 · Cited by 752
Kelley, A. E., & Domesick, V. B. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90198-1 · Cited by 746
Lipska, B. K., Jaskiw, G. E., & Weinberger, D. R. (1993) · Neuropsychopharmacology · doi:10.1038/npp.1993.44 · Cited by 697
Morris, R., Schenk, F., Tweedie, F., & Jarrard, L. E. (1990) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1990.tb00014.x · Cited by 666
Associations across time: The hippocampus as a temporary memory store
Rawlins, J. N. P. (1985) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00001291 · Cited by 561
Self-citationSharp, T., Zetterström, T., Ljungberg, T., & Ungerstedt, U. (1987) · Brain Research · doi:10.1016/0006-8993(87)91416-8 · Cited by 395
Configural association theory and the hippocampal formation: An appraisal and reconfiguration
Rudy, J. W., & Sutherland, R. J. (1995) · Hippocampus · doi:10.1002/hipo.450050502 · Cited by 383
Topographical organization of the entorhinal projection to the dentate gyrus of the monkey
Witter, M., Hoesen, G. W. V., & Amaral, D. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-01-00216.1989 · Cited by 380
Jarrard, L. E. (1983) · Behavioral Neuroscience · doi:10.1037//0735-7044.97.6.873 · Cited by 371
Sams-Dodd, F., Lipska, B. K., & Weinberger, D. R. (1997) · Psychopharmacology · doi:10.1007/s002130050349 · Cited by 346
Anger, D. (1956) · Journal of Experimental Psychology · doi:10.1037/h0041255 · Cited by 337
Honey, R. C., & Good, M. A. (1993) · Behavioral Neuroscience · doi:10.1037//0735-7044.107.1.23 · Cited by 334
Richmond, M. A., Yee, B. K., Pouzet, B., Veenman, L., Rawlins, J. N. P., Feldon, J., & Bannerman, D. M. (1999) · Behavioral Neuroscience · doi:10.1037/0735-7044.113.6.1189 · Cited by 332
On the use of ibotenic acid to lesion selectively different components of the hippocampal formation
Jarrard, L. E. (1989) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(89)90149-0 · Cited by 285
Totterdell, S., & Smith, A. D. (1989) · PubMed · Cited by 266
Latent inhibition of conditioned dopamine release in rat nucleus accumbens
Young, A. M. J., Joseph, M. H., & Gray, J. A. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90378-s · Cited by 261
The cytoarchitecture, histochemistry and projections of the tuberomammillary nucleus in the rat
Köhler, C., Swanson, L. W., Haglund, L., & J-Yen, W. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90049-1 · Cited by 253
The septo-hippocampal system and cognitive mapping
Rawlins, J. N. P., & Olton, D. S. (1982) · Behavioural Brain Research · doi:10.1016/0166-4328(82)90039-0 · Cited by 226
Differential Effects of Dorsal and Ventral Hippocampal Lesions
Hock, B. J., & Bunsey, M. D. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-17-07027.1998 · Cited by 220
Herman, J. P., Cullinan, W. E., Morano, M. I., Akil, H., & Watson, S. J. (1995) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1995.tb00784.x · Cited by 214
Lipska, B. K., Jaskiw, G. E., Chrapusta, S. J., Karoum, F., & Weinberger, D. R. (1992) · Brain Research · doi:10.1016/0006-8993(92)91184-g · Cited by 205
Ruth, R. E., Collier, T. J., & Routtenberg, A. (1982) · The Journal of Comparative Neurology · doi:10.1002/cne.902090107 · Cited by 186
Witter, M. P., & Groenewegen, H. J. (1984) · The Journal of Comparative Neurology · doi:10.1002/cne.902240305 · Cited by 178
Whishaw, I. Q., & Jarrard, L. E. (1995) · Hippocampus · doi:10.1002/hipo.450050610 · Cited by 152
Connections of the parahippocampal cortex. I. Cortical afferents
Room, P., & Groenewegen, H. J. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902510402 · Cited by 152
Herman, J. P., Cullinan, W. E., Young, E. A., Akil, H., & Watson, S. J. (1992) · Brain Research · doi:10.1016/0006-8993(92)91680-d · Cited by 144
Chiara, G. D., Tanda, G., Frau, R., & Carboni, E. (1993) · Psychopharmacology · doi:10.1007/bf02244939 · Cited by 125
Hippocampal Lesions Disrupt an Associative Mismatch Process
Honey, R. C., Watt, A., & Good, M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-06-02226.1998 · Cited by 124
Selective cytotoxic lesions of the hippocampal formation and DRL performance in rats.
Sinden, J. D., Rawlins, J. N. P., Gray, J. A., & Jarrard, L. E. (1986) · Behavioral Neuroscience · doi:10.1037//0735-7044.100.3.320 · Cited by 112
Köhler, C., Ericson, H., Watanabe, T., Polak, J. M., Palay, S. L., Chan‐Palay, V., & Chan‐Palay, V. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902500105 · Cited by 110
Wilkinson, L. S., Mittleman, G., Torres, E. M., Humby, T., Hall, F. S., & Robbins, T. W. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90110-c · Cited by 107
Hurd, Y. L., & Ungerstedt, U. (1989) · European Journal of Pharmacology · doi:10.1016/0014-2999(89)90067-8 · Cited by 95
Dorsal hippocampal lesion does not affect dopaminergic indices in the basal ganglia
Lipska, B. K., Jaskiw, G. E., Karoum, F., Phillips, I., Kleinman, J. E., & Weinberger, D. R. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90342-y · Cited by 20
SENSITIZATION OF DA RELEASE IN THE ACCUMBENS FOLLOWING AMPHETAMINE
Warburton, E. C., Sn, M., & Mh, J. (1993) · Behavioural Pharmacology · doi:10.1097/00008877-199308000-00055 · Cited by 7
Cited by
Sorted by citations
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
Fanselow, M. S., & Dong, H.-W. (2010) · Neuron · doi:10.1016/j.neuron.2009.11.031 · Cited by 3,358
Regional dissociations within the hippocampus-memory and anxiety
Bannerman, D. M., Rawlins, J. N. P., McHugh, S. B., Deacon, R. M. J., Yee, B. K., Bast, T., Zhang, W.-N., Pothuizen, H. H. J., & Feldon, J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.03.004 · Cited by 1,462
Spatial memory, recognition memory, and the hippocampus
Broadbent, N. J., Squire, L. R., & Clark, R. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406344101 · Cited by 985
Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus
Kheirbek, M. A., Drew, L. J., Burghardt, N. S., Costantini, D. O., Tannenholz, L., Ahmari, S. E., Zeng, H., Fenton, A. A., & Hen, R. (2013) · Neuron · doi:10.1016/j.neuron.2012.12.038 · Cited by 713
Hippocampal synaptic plasticity, spatial memory and anxiety
Bannerman, D. M., Sprengel, R., Sanderson, D. J., McHugh, S. B., Rawlins, J. N. P., Monyer, H., & Seeburg, P. H. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3677 · Cited by 688
Metadata
- Authors
- Bannerman, D. M., Yee, B. K., Good, M. A., Heupel, M. J., Iversen, S. D., & Rawlins, J. N. P.
- Affiliations
- University of Oxford (GB)
- Venue
- Behavioral Neuroscience
- Published
- 1999
- Volume
- 113
- Issue
- 6
- Pages
- 1170-1188
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- OpenAlex
- W2037522799
- Cited by
- 397
- References
- 50
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 5 · 2023: 6 · 2022: 10 · 2021: 11 · 2020: 12 · 2019: 17 · 2018: 19 · 2017: 18 · 2016: 15 · 2015: 16 · 2014: 24 · 2013: 22 · 2012: 20
- FWCI
- 5.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- hippocampus, double dissociation, dorsal hippocampus, ventral hippocampus, cytotoxic lesions, spatial memory, water maze, elevated T-maze, hyperactivity, differential reinforcement of low rates, footshock, septotemporal axis, rats
- MeSH terms
- Analysis of Variance, Animals, Hippocampus, Hyperkinesis, Locomotion, Male, Microinjections, Rats, Inbred Strains, Space Perception, N-Methylaspartate, Excitatory Amino Acid Antagonists, Maze Learning, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review