LGB-affirmative cognitive-behavioral therapy for young adult gay and bisexual men: a randomized controlled trial of a transdiagnostic minority stress approach
Open accessAbstract
OBJECTIVES: We tested the preliminary efficacy of a transdiagnostic cognitive-behavioral treatment adapted to improve depression, anxiety, and co-occurring health risks (i.e., alcohol use, sexual compulsivity, condomless sex) among young adult gay and bisexual men. Treatment adaptations focused on reducing minority stress processes that underlie sexual orientation-related mental health disparities. METHOD: Young gay and bisexual men (n = 63; M age = 25.94) were randomized to immediate treatment or a 3-month waitlist. At baseline, 3-month, and 6-month assessments, participants completed self-reports of mental health and minority stress and an interview of past-90-day risk behavior. RESULTS: Compared to waitlist, treatment significantly reduced depressive symptoms (b = -2.43, 95% CI: -4.90, 0.35, p < .001), alcohol use problems (b = -3.79, 95% CI: -5.94, -1.64, p < .001), sexual compulsivity (b = -5.09, 95% CI: -8.78, -1.40, p < .001), and past-90-day condomless sex with casual partners (b = -1.09, 95% CI: -1.80, -0.37, p < .001), and improved condom use self-efficacy (b = 10.08, 95% CI: 3.86, 16.30, p < .001). The treatment yielded moderate and marginally significant greater improvements than waitlist in anxiety symptoms (b = -2.14, 95% CI: -4.61, 0.34, p = .09) and past-90-day heavy drinking (b = -0.32, 95% CI: -0.71, 0.07, p = .09). Effects were generally maintained at follow-up. Minority stress processes showed small improvements in the expected direction. CONCLUSION: This study demonstrated preliminary support for the first intervention adapted to address gay and bisexual men's co-occurring health problems at their source in minority stress. If found to be efficacious compared to standard evidence-based treatments, the treatment will possess substantial potential for helping clinicians translate LGB-affirmative treatment guidelines into evidence-based practice. (PsycINFO Database Record
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Condomless anal sex was assessed over the past 30 days rather than a longer period to reduce retrospective recall bias, but this may have limited variability in HIV-transmission-risk acts.
“condomless anal sex was assessed across the past 30 days rather than over a longer period (Pachankis, Hatzenbuehler, et al., 2015) so as to guard against retrospective recall bias introduced by reporting across longer periods. Yet, this decision might have limited variability in HIV-transmission-risk acts.”
From Guided internet-based LGBTQ-affirmative cognitive-behavioral therapy: A randomized controlled trial among sexual minority men in China (2024) · cites this paper as Pachankis, Hatzenbuehler, et al., 2015
The Method section (Primary Outcome Measures) says condomless anal sex was assessed over the past 90 days, not 30 days. The Analytic plan likewise describes the outcome as a past-90-day count. The cited paper therefore contradicts the assessment period attributed to it. (LLM, conf=0.92)
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Experimental — accuracy not yet measuredPachankis identified "overarching treatment principles" stemming from the minority stress model, which have been successfully used in interventions designed to address syndemic conditions experienced by gay and bisexual men and alcohol misuse among sexual minority women.
“Pachankis [33] identified “overarching treatment principles” stemming from the minority stress model, which have been successfully used in interventions designed to address syndemic conditions experienced by gay and bisexual men and alcohol misuse among sexual minority women [34,35].”
From Minority stress theory: Application, critique, and continued relevance (2023) · cites this paper as [35]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredOnly one randomized controlled trial has been conducted with sexual minority young people to test a CBT-based intervention targeting mental health outcomes-ESTEEM.
“To the authors’ knowledge, only one randomized controlled trial has been conducted with sexual minority young people to test a CBT-based intervention targeting mental health outcomes—ESTEEM (Effective Skills to Empower Effective Men) [31,32,33].”
From Findings from a feasibility study of an adapted cognitive behavioral therapy group intervention to reduce depression among lgbtq (Lesbian, gay, bisexual, transgender, or queer) young people (2019) · cites this paper as [33]
The Method (Procedure; page unavailable) reports that 63 participants were randomized, and the Discussion describes ESTEEM as a CBT-based treatment that improved depressive symptoms in young gay and bisexual men. This identifies the cited study as a trial of the kind described, but the paper does not establish that it was the only such trial among all sexual minority young people. (LLM, conf=0.82)
Experimental — accuracy not yet measuredTreatment effects for mental and behavioral problems, minority stress, and universal risk factors were in the expected direction and consistent with previous research on LGBTQ-affirmative CBT and psychosocial interventions for sexual minority individuals.
“Overall, treatment effects for mental and behavioral problems and minority stress and universal risk factors were in the expected direction and consistent with previous research on LGBTQ-affirmative CBT specifically (Craig, Eaton, et al., 2021; Pachankis, Hatzenbuehler, et al., 2015; Pachankis, McConocha, et al., 2020) and psychosocial interventions focused on sexual minority individuals’ co-occur”
From Guided internet-based LGBTQ-affirmative cognitive-behavioral therapy: A randomized controlled trial among sexual minority men in China (2024) · cites this paper as Pachankis, Hatzenbuehler, et al., 2015
The tailoring process incorporated suggestions from the literature where comparable interventions have been successfully tested with the LGBTQ+ community.
“We have also incorporated other suggestions from the literature [25,26], where comparable interventions have been successfully tested with the LGBTQ+ community.”
From An Internet-Based Intervention to Increase the Ability of Lesbian, Gay, and Bisexual People to Cope With Adverse Events: Single-Group Feasibility Study (2024) · cites this paper as [26]
In studies of men who have sex with men, self-reported compulsive sexual behaviour has been found to be correlated with depression, anxiety, and minority stress, and to be associated with higher rates of sexual risk-taking behaviours.
“In studies of men who have sex with men, self-reported compulsive sexual behaviour has been found to be correlated with depression 251 , anxiety 252 , and minority stress (i.e., the stress associated with stigma-related social disadvantage that compounds general life stress) 253 , as well as to be associated with higher rates of sexual risk-taking behaviours 254,255 .”
ESTEEM (N = 63) was conducted in New York City and designed specifically for gay and bisexual men aged 18-35 years as the target population.
“ESTEEM (N = 63) was conducted in New York City and designed specifically for gay and bisexual men aged 18–35 years as the target population [33].”
ESTEEM outcome evaluation findings are encouraging in terms of reduced depressive symptoms, alcohol use problems, and sexual risk behaviors.
“Although the outcome evaluation findings are encouraging in terms of reduced depressive symptoms, alcohol use problems, and sexual risk behaviors”
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Self-citation
- Authors
- Pachankis, J. E., Hatzenbuehler, M. L., Rendina, H. J., Safren, S. A., & Parsons, J. T.
- Affiliations
- Yale University (US)
- Columbia University (US)
- Harvard University (US)
- ORCID
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2015-10
- Volume
- 83
- Issue
- 5
- Pages
- 875-889
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC4573250
- OpenAlex
- W2274662974
- Cited by
- 619
- References
- 67
- Citations by year
- 2026: 41 · 2025: 54 · 2024: 66 · 2023: 56 · 2022: 87 · 2021: 60 · 2020: 67 · 2019: 70 · 2018: 45 · 2017: 45 · 2016: 22 · 2015: 6
- FWCI
- 64.36
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R34-MH096607, K24 MH094214)
- Topics
- Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- minority stress, gay and bisexual men, young men, depression, anxiety, alcohol consumption, compulsive sexual behavior, unprotected sex, condom use self-efficacy, transdiagnostic treatment, cognitive behavioral therapy, health risk behaviors, treatment efficacy, waitlist control, sexual minority mental health
- MeSH terms
- Adolescent, Adult, Mental Disorders, Bisexuality, Follow-Up Studies, Humans, Male, Minority Groups, Risk-Taking, Stress, Psychological, Cognitive Behavioral Therapy, Treatment Outcome, Homosexuality, Male, Young Adult, Self Report
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