Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Howitz, Konrad T., Bitterman, Kevin J., Cohen, Haim Y., Lamming, Dudley W., Lavu, Siva, Wood, Jason G., Zipkin, Robert E., Chung, Phuong, Kisielewski, Anne, Zhang, Li-Li, Scherer, Brandy, Sinclair, David A.·2003·Nature
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Items 101–200 of 1,038
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- Plants vs. Cancer: A Review on Natural Phytochemicals in Preventing and Treating Cancers and Their DruggabilityHu Wang, Tin Oo Khor, Limin Shu, Zheng‐Yuan Su, Francisco Fuentes, Jong Hun Lee, Ah‐Ng Tony Kong · 2012 · Anti-Cancer Agents in Medicinal Chemistry
- Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and agingCarolina Simioni, Giorgio Zauli, Alberto Maria Martelli, Marco Vitale, Gianni Sacchetti, Arianna Gonelli, Luca Maria Neri · 2018 · Oncotarget
- Nuclear Trapping of the Forkhead Transcription Factor FoxO1 via Sirt-dependent Deacetylation Promotes Expression of Glucogenetic GenesDavid Frescas, Luca V. C. Valenti, Domenico Accili · 2005 · Journal of Biological Chemistry
- Cardiovascular Protective Effects of ResveratrolSilvia Bradamante, Livia Barenghi, Alessandro Maria Villa · 2004 · Cardiovascular Drug Reviews
- SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary diseaseRajendrasozhan, Saravanan, Yang, Se-Ran, Kinnula, Vuokko L., Rahman, Irfan · 2008 · American Journal of Respiratory and Critical Care Medicine
- The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseasesXuejia Yang · 2004 · Nucleic Acids Research
- Sirtuins, Aging, and MedicineGuarente, Leonard · 2011 · New England Journal of Medicine
- Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neuronsJ. Alex Parker, Margarita Arango-Lievano, Salima Abderrahmane, Emmanuel Lambert, Cendrine Tourette, Hélène Catoire, Christian Néri · 2005 · Nature Genetics
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- Sirtuins and NAD + in the Development and Treatment of Metabolic and Cardiovascular DiseasesAlice E. Kane, David A. Sinclair · 2018 · Circulation Research
- Disruption of the Ang II type 1 receptor promotes longevity in miceAriela Benigni, Daniela Corna, Carla Zoja, Aurelio Sonzogni, Roberto Latini, Monica Salio, Sara Conti, Daniela Rottoli, Lorena Longaretti, Paola Cassis et al. · 2009 · Journal of Clinical Investigation
- AMPK at the Nexus of Energetics and AgingBurkewitz, Kristopher, Zhang, Yue, Mair, William B. · 2014 · Cell Metabolism
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- Berries: Improving Human Health and Healthy Aging, and Promoting Quality Life—A ReviewOctavio Paredes‐López, Martha L. Cervantes-Ceja, M. Vigna-Pérez, Talía Hernández‐Pérez · 2010 · Plant Foods for Human Nutrition
- Oxidative stress and aberrant signaling in aging and cognitive declineDröge, Wulf, Schipper, Hyman M. · 2007 · Aging Cell
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- The ageing epigenome and its rejuvenationZhang, Weiqi, Qu, Jing, Liu, Guang-Hui, Belmonte, Juan Carlos Izpisua · 2020 · Nature Reviews Molecular Cell Biology
- Sirtuins, a promising target in slowing down the ageing processGrabowska, Wioleta, Sikora, Ewa, Bielak-Zmijewska, Anna · 2017 · Biogerontology
- Regulation of Hypoxia-Inducible Factor 2α Signaling by the Stress-Responsive Deacetylase Sirtuin 1Elhadji M. Dioum, Rui Chen, Matthew S. Alexander, Quiyang Zhang, Richard T. Hogg, Robert D. Gerard, Joseph A. Garcia · 2009 · Science
- Autophagy: for better or for worseEllen Wirawan, Tom Vanden Berghe, Saskia Lippens, Patrizia Agostinis, Peter Vandenabeele · 2011 · Cell Research
- Lysine Acetylation Is a Highly Abundant and Evolutionarily Conserved Modification in Escherichia ColiJunmei Zhang, Robert W. Sprung, Jimin Pei, Xiaohong Tan, Sungchan Kim, Heng Zhu, Chuan‐Fa Liu, Nick V. Grishin, Yingming Zhao · 2008 · Molecular & Cellular Proteomics
- Calorie restriction and sirtuins revisitedGuarente, Leonard · 2013 · Genes & Development
- Essential role for autophagy in life span extensionMadeo, Frank, Zimmermann, Andreas, Maiuri, Maria Chiara, Kroemer, Guido · 2015 · Journal of Clinical Investigation
- Negative regulation of the deacetylase SIRT1 by DBC1Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin, Wei Jun Gu · 2008 · Nature
- Sirtuin activators and inhibitors: Promises, achievements, and challengesDai, Han, Sinclair, David A., Ellis, James L., Steegborn, Clemens · 2018 · Pharmacology & Therapeutics
- Oxidative stress in asthma and COPD: Antioxidants as a therapeutic strategyPaul Kirkham, Irfan Rahman · 2006 · Pharmacology & Therapeutics
- Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging ProcessAntero Salminen, Kai Kaarniranta, Anu Kauppinen · 2013 · International Journal of Molecular Sciences
- High-Dose Resveratrol Supplementation in Obese MenPoulsen, Morten M., Vestergaard, Poul F., Clasen, Berthil F., Radko, Yulia, Christensen, Lars P., Stødkilde-Jørgensen, Hans, Møller, Niels, Jessen, Niels, Pedersen, Steen B., Jørgensen, Jens Otto L. · 2013 · Diabetes
- Sirt1 contributes critically to the redox-dependent fate of neural progenitorsProzorovski, Timour, Schulze-Topphoff, Ulf, Glumm, Robert, Baumgart, Jan, Schröter, Friederike, Ninnemann, Olaf, Siegert, Elise, Bendix, Ivo, Brüstle, Oliver, Nitsch, Robert et al. · 2008 · Nature Cell Biology
- Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human EvidenceJoão Tomé‐Carneiro, Mar Larrosa, Antonio González‐Sarrías, Francisco Abraham Tomás-Barberán, María‐Teresa García‐Conesa, Juan Carlos Espı́n · 2013 · Current Pharmaceutical Design
- Resveratrol induces mitochondrial biogenesis in endothelial cellsAnna Csiszár, Nazar Labinskyy, John Thomas Pinto, Praveen Ballabh, Hanrui Zhang, György Losonczy, Kevin J. Pearson, Rafael de Cabo, Pál Pacher, Cuihua Zhang et al. · 2009 · American Journal of Physiology-Heart and Circulatory Physiology
- Resveratrol: French Paradox RevisitedCatalgol, Betul, Batirel, Saime, Taga, Yavuz, Ozer, Nesrin Kartal · 2012 · Frontiers in Pharmacology
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- Challenges for Research on Polyphenols from Foods in Alzheimer’s Disease: Bioavailability, Metabolism, and Cellular and Molecular MechanismsManjeet Singh, Madeleine Arseneault, J. Thomas Sanderson, Ven Murthy, Charles Ramassamy · 2008 · Journal of Agricultural and Food Chemistry
- Sirtuin signaling in cellular senescence and agingShin-Hae Lee, Ji-Hyeon Lee, Hye‐Yeon Lee, Kyung‐Jin Min · 2019 · BMB Reports
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- The landscape of agingYusheng Cai, Wei Song, Jiaming Li, Ying Jing, Chuqian Liang, Liyuan Zhang, Xia Zhang, Wenhui Zhang, Beibei Liu, Yongpan An et al. · 2022 · Science China Life Sciences
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- Resveratrol is not a direct activator of SIRT1 enzyme activityBeher, Dirk, Wu, John, Cumine, Suzanne, Kim, Ki Won, Lu, Shu‐Chen, Atangan, Larissa, Wang, Minghan · 2009 · Chemical Biology & Drug Design
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