DNA targeting specificity of RNA-guided Cas9 nucleases

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Items 101–200 of 1,040

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   Junwei Shi, Eric Wang, Joseph P. Milazzo, Zihua Wang, Justin B. Kinney, Christopher R. Vakoc · 2015 · Nature Biotechnology
2. Genome editing in rice and wheat using the CRISPR/Cas system
   Qiwei Shan, Yanpeng Wang, Jun Li, Caixia Gao · 2014 · Nature Protocols
3. DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins
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6. A Natural Allele of a Transcription Factor in Rice Confers Broad-Spectrum Blast Resistance
   Weitao Li, Ziwei Zhu, Mawsheng Chern, Junjie Yin, Chao Yang, Li Ran, Mengping Cheng, Min He, Kang Wang, Jing Wang et al. · 2017 · Cell
7. Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection
   Liang, Xiquan, Potter, Jason, Kumar, Shantanu, Zou, Yanfei, Quintanilla, Rene, Sridharan, Mahalakshmi, Carte, Jason, Chen, Wen, Roark, Natasha, Ranganathan, Sridhar et al. · 2015 · Journal of Biotechnology
8. Genome-editing Technologies for Gene and Cell Therapy
   Morgan L. Maeder, Charles A. Gersbach · 2016 · Molecular Therapy
9. A split-Cas9 architecture for inducible genome editing and transcription modulation
   Bernd Zetsche, Sara E. Volz, Feng Zhang · 2015 · Nature Biotechnology
10. A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
    Lowder, Levi G., Zhang, Dengwei, Baltes, Nicholas J., Paul, Joseph W., Tang, Xu, Zheng, Xuelian, Voytas, Daniel F., Hsieh, Tzung-Fu, Zhang, Yong, Qi, Yiping · 2015 · Plant Physiology
11. A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi
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12. Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
    Frock, Richard L, Hu, Jiazhi, Meyers, Robin M, Ho, Yu-Jui, Kii, Erina, Alt, Frederick W · 2015 · Nature Biotechnology
13. Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
    Baubec, Tuncay, Colombo, Daniele F., Wirbelauer, Christiane, Schmidt, Juliane, Burger, Lukas, Krebs, Arnaud R., Akalin, Altuna, Schübeler, Dirk · 2015 · Nature
14. Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
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15. CRISPR/Cas9 for genome editing: progress, implications and challenges
    Feng Zhang, Y. Wen, Xiong Guo · 2014 · Human Molecular Genetics
16. DeepCRISPR: Optimized CRISPR guide RNA design by deep learning
    Chuai, Guohui, Ma, Hanhui, Yan, Jifang, Chen, Ming, Hong, Nanfang, Xue, Dongyu, Zhou, Chi, Zhu, Chenyu, Chen, Ke, Duan, Bin et al. · 2018 · Genome biology
17. CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences
    Lin, Y., Cradick, T. J., Brown, M. T., Deshmukh, H., Ranjan, P., Sarode, N., Wile, B. M., Vertino, P. M., Stewart, F. J., Bao, G. · 2014 · Nucleic Acids Research
18. Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis
    Zhengyan Feng, Yanfei Mao, Nanfei Xu, Botao Zhang, Pengliang Wei, Dong‐Lei Yang, Zhen Wang, Zhengjing Zhang, Rui Zheng, Lan Yang et al. · 2014 · Proceedings of the National Academy of Sciences
19. Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
    Ramakrishna, Suresh, Kwaku Dad, Abu-Bonsrah, Beloor, Jagadish, Gopalappa, Ramu, Lee, Sang-Kyung, Kim, Hyongbum · 2014 · Genome Research
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    Matthew J. Shurtleff, Kate V. Karfilis, Morayma M. Temoche-Diaz, Sayaka Ri, Randy W. Schekman · 2016 · eLife
21. A Multifunctional AAV-CRISPR-Cas9 and Its Host Response
    Chew, Wei Leong, Tabebordbar, Mohammadsharif, Cheng, Jason K W, Mali, Prashant, Wu, Elizabeth Y, Ng, Alex H M, Zhu, Kexian, Wagers, Amy J, Church, George M · 2016 · Nature Methods
22. Sequence determinants of improved CRISPR sgRNA design
    Xu, Han, Xiao, Tengfei, Chen, Chen-Hao, Li, Wei, Meyer, Clifford A., Wu, Qiu, Wu, Di, Cong, Le, Zhang, Feng, Liu, Jun S. et al. · 2015 · Genome Research
23. Off-target effects in CRISPR/Cas9 gene editing
    Guo, Congting, Ma, Xiaoteng, Gao, Fei, Guo, Yuxuan · 2023 · Frontiers in Bioengineering and Biotechnology
24. Photoactivatable CRISPR-Cas9 for optogenetic genome editing
    Yuta Nihongaki, Fuun Kawano, Takahiro Nakajima, Moritoshi Sato · 2015 · Nature Biotechnology
25. Correction of a genetic disease in mouse via use of CRISPR-Cas9
    Wu, Yuxuan, Liang, Dan, Wang, Yinghua, Bai, Meizhu, Tang, Wei, Bao, Shiming, Yan, Zhiqiang, Li, Dangsheng, Li, Jinsong · 2013 · Cell stem cell
26. Conventional and Molecular Techniques from Simple Breeding to Speed Breeding in Crop Plants: Recent Advances and Future Outlook
    Sunny Ahmar, Rafaqat A. Gill, Ki‐Hong Jung, Aroosha Faheem, Muhammad Uzair Qasim, Mustansar Mubeen, Weijun Zhou · 2020 · International Journal of Molecular Sciences
27. Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice
    Huanbin Zhou, Bo Liu, Donald P. Weeks, Martin H. Spalding, Bing Yang · 2014 · Nucleic Acids Research
28. Delivery technologies for genome editing
    Yin, Hao, Kauffman, Kevin J., Anderson, Daniel G. · 2017 · Nature Reviews Drug Discovery
29. CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
    Cradick, Thomas J., Fine, Eli J., Antico, Christopher J., Bao, Gang · 2013 · Nucleic Acids Research
30. Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system
    Khaoula Belhaj, Angela Chaparro‐Garcia, Sophien Kamoun, Vladimir Nekrasov · 2013 · Plant Methods
31. CRISPR Gene Therapy: Applications, Limitations, and Implications for the Future
    Fathema Z. Uddin, Charles M. Rudin, Triparna Sen · 2020 · Frontiers in Oncology
32. Sequence modeling and design from molecular to genome scale with Evo
    Nguyen, Eric, Poli, Michael, Durrant, Matthew G., Kang, Brian, Katrekar, Dhruva, Li, David B., Bartie, Liam J., Thomas, Armin W., King, Samuel H., Brixi, Garyk et al. · 2024 · Science
33. Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila
    Shu Kondo, Ryu Ueda · 2013 · Genetics
34. CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery
    Wang, Hong-Xia, Li, Mingqiang, Lee, Ciaran M., Chakraborty, Syandan, Kim, Hae-Won, Bao, Gang, Leong, Kam W. · 2017 · Chemical Reviews
35. Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing
    Heckl, Dirk, Kowalczyk, Monika S, Yudovich, David, Belizaire, Roger, Puram, Rishi V, McConkey, Marie E, Thielke, Anne, Aster, Jon C, Regev, Aviv, Ebert, Benjamin L · 2014 · Nature Biotechnology
36. Multiplexed CRISPR technologies for gene editing and transcriptional regulation
    Nicholas S. McCarty, Alicia E. Graham, Lucie Studená, Rodrigo Ledesma‐Amaro · 2020 · Nature Communications
37. Generating genetically modified mice using CRISPR/Cas-mediated genome engineering
    Hui Yang, Haoyi Wang, Rudolf Jaenisch · 2014 · Nature Protocols
38. Genome Engineering with Targetable Nucleases
    Carroll, Dana · 2014 · Annual Review of Biochemistry
39. CRISPR/Cas system: recent advances and future prospects for genome editing
    Manghwar, Hakim, Lindsey, Keith, Zhang, Xianlong, Jin, Shuangxia · 2019 · Trends in Plant Science
40. Editing plant genomes with CRISPR/Cas9
    Khaoula Belhaj, Angela Chaparro‐Garcia, Sophien Kamoun, Nicola J. Patron, Vladimir Nekrasov · 2014 · Current Opinion in Biotechnology
41. Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9
    Rajat M. Gupta, Kiran Musunuru · 2014 · Journal of Clinical Investigation
42. Induced Pluripotent Stem Cells Meet Genome Editing
    Hockemeyer, Dirk, Jaenisch, Rudolf · 2016 · Cell Stem Cell
43. Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts
    Mariette Andersson, Helle Turesson, Alessandro Nicolia, Ann‐Sofie Fält, Mathias Samuelsson, Per Hofvander · 2016 · Plant Cell Reports
44. RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
    Hu, Wenhui, Kaminski, Rafal, Yang, Fan, Zhang, Yonggang, Cosentino, Laura, Li, Fang, Luo, Biao, Alvarez-Carbonell, David, Garcia-Mesa, Yoelvis, Karn, Jonathan et al. · 2014 · Proceedings of the National Academy of Sciences
45. Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9
    Hongmei Li, Naoko Fujimoto, Noriko Sasakawa, Saya Shirai, Tokiko Ohkame, T. Sakuma, Michihiro Tanaka, Naoki Amano, Akira Watanabe, H. Sakurai et al. · 2014 · Stem Cell Reports
46. Directed evolution of CRISPR-Cas9 to increase its specificity
    Lee, Jungjoon K., Jeong, Euihwan, Lee, Joonsun, Jung, Minhee, Shin, Eunji, Kim, Young-hoon, Lee, Kangin, Jung, Inyoung, Kim, Daesik, Kim, Seokjoong et al. · 2018 · Nature Communications
47. Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR
    Michael Boettcher, Michael T. McManus · 2015 · Molecular Cell
48. Recent advancements in molecular marker-assisted selection and applications in plant breeding programmes
    Nazarul Hasan, Sana Choudhary, Neha Naaz, Nidhi Sharma, Rafiul Amin Laskar · 2021 · Journal of Genetic Engineering and Biotechnology
49. Genome Engineering Using CRISPR-Cas9 System
    Le Cong, Feng Zhang · 2014 · Methods in molecular biology
50. Inheritable silencing of endogenous genes by hit-and-run targeted epigenetic editing
    Amabile, Angelo, Migliara, Alessandro, Capasso, Paola, Biffi, Mauro, Cittaro, Davide, Naldini, Luigi, Lombardo, Angelo · 2016 · Cell
51. Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
    Shengdar Q. Tsai, J. Keith Joung · 2016 · Nature Reviews Genetics
52. High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9
    Gaurav K. Varshney, Wuhong Pei, Matthew C. LaFave, Jennifer Idol, Lisha Xu, Viviana E. Gallardo, Blake Carrington, Kevin S. Bishop, MaryPat S. Jones, Mingyu Li et al. · 2015 · Genome Research
53. Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells
    DeWitt, Mark A., Magis, Wendy, Bray, Nicolas L., Wang, Tianjiao, Berman, Jennifer R., Urbinati, Fabrizia, Heo, Seok-Jin, Mitros, Therese, Muñoz, Denise P., Boffelli, Dario et al. · 2016 · Science Translational Medicine
54. An iCRISPR platform for rapid, multiplexable and inducible genome editing in human pluripotent stem cells
    F. Gonzãlez, Zengrong Zhu, Zhong Shi, K. Lelli, N. Verma, Qing V. Li, D. Huangfu · 2014 · Cell Stem Cell
55. Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions
    Sumiyo Morita, Hirofumi Noguchi, Takuro Horii, Kazuhiko Nakabayashi, Mika Kimura, K. Okamura, Atsuhiko Sakai, Hideyuki Nakashima, Kenichiro Hata, Kinichi Nakashima et al. · 2016 · Nature Biotechnology
56. Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
    Shota Nakade, Takuya Tsubota, Yuto Sakane, Satoshi Kume, Naoaki Sakamoto, Masanobu Obara, Takaaki Daimon, Hideki Sezutsu, Takashi Yamamoto, Tetsushi Sakuma et al. · 2014 · Nature Communications
57. The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112
    Nhan van Tran, Felix G.M. Ernst, Ben R Hawley, Christiane Zorbas, Nathalie Ulryck, Philipp Hackert, Katherine E. Bohnsack, Markus T. Bohnsack, Samie R. Jaffrey, Marc Graille et al. · 2019 · Nucleic Acids Research
58. Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites
    Jeongbin Park, Sangsu Bae, Jin‐Soo Kim · 2015 · Bioinformatics
59. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9
    Mandal, Pankaj K., Ferreira, Leonardo M.R., Collins, Ryan, Meissner, Torsten B., Boutwell, Christian L., Friesen, Max, Vrbanac, Vladimir, Garrison, Brian S., Stortchevoi, Alexei, Bryder, David et al. · 2014 · Cell stem cell
60. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
    Mumbach, Maxwell R, Satpathy, Ansuman T, Boyle, Evan A, Dai, Chao, Gowen, Benjamin G, Cho, Seung Woo, Nguyen, Michelle L, Rubin, Adam J, Granja, Jeffrey M, Kazane, Katelynn R et al. · 2017 · Nature Genetics
61. Autism genes converge on asynchronous development of shared neuron classes
    Paulsen, Bruna, Velasco, Silvia, Kedaigle, Amanda J., Pigoni, Martina, Quadrato, Giorgia, Deo, Anthony J., Adiconis, Xian, Uzquiano, Ana, Sartore, Rafaela, Yang, Sung Min et al. · 2022 · Nature
62. CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae
    Robert Mans, Harmen M. van Rossum, Melanie Wijsman, Antoon H. Backx, Niels G. A. Kuijpers, Marcel A. van den Broek, Pascale A. S. Daran-Lapujade, Jack T. Pronk, Antonius J. A. van Maris, Jean-Marc G Daran · 2015 · FEMS Yeast Research
63. Mapping the genomic landscape of CRISPR-Cas9 cleavage
    Cameron, Peter, Fuller, Chris K, Donohoue, Paul D, Jones, Brittnee N, Thompson, Matthew S, Carter, Matthew M, Gradia, Scott, Vidal, Bastien, Garner, Elizabeth, Slorach, Euan M et al. · 2017 · Nature Methods
64. CRISPR/Cas9 Platforms for Genome Editing in Plants: Developments and Applications
    Xingliang Ma, Qinlong Zhu, Yuanling Chen, Yao‐Guang Liu · 2016 · Molecular Plant
65. Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting
    Kim, Seung Min, Yang, Yoosoo, Oh, Seung Ja, Hong, Yeonsun, Seo, Minkoo, Jang, Mihue · 2017 · Journal of Controlled Release
66. CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations
    Cullot, Grégoire, Boutin, Julian, Toutain, Jérôme, Prat, Florence, Pennamen, Perrine, Rooryck, Caroline, Teichmann, Martin, Rousseau, Emilie, Lamrissi-Garcia, Isabelle, Guyonnet-Duperat, Véronique et al. · 2019 · Nature Communications
67. Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
    Matthew T. N. Yarnall, Eleonora I. Ioannidi, Cian Schmitt-Ulms, Rohan N. Krajeski, Justin Lim, Lukas Villiger, Wenyuan Zhou, Kaiyi Jiang, Sofya K. Garushyants, Nathaniel Roberts et al. · 2022 · Nature Biotechnology
68. Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
    Veres, Adrian, Gosis, Bridget S., Ding, Qiurong, Collins, Ryan, Ragavendran, Ashok, Brand, Harrison, Erdin, Serkan, Cowan, Chad A., Talkowski, Michael E., Musunuru, Kiran · 2014 · Cell Stem Cell
69. Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy
    Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A. · 2015 · Nature Communications
70. Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
    Joshua Chiou, Ryan J. Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Rebecca L. Melton, Elisha Beebe, Paola Benaglio, Serina Huang, Katha Korgaonkar et al. · 2021 · Nature
71. Analyzing CRISPR genome-editing experiments with CRISPResso
    Luca Pinello, Matthew C. Canver, Megan D. Hoban, Stuart H. Orkin, Donald B. Kohn, Daniel E. Bauer, Guo‐Cheng Yuan · 2016 · Nature Biotechnology
72. Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia
    Miriam Y. Kim, Kyung–Rok Yu, Saad S. Kenderian, Marco Ruella, Shirley Chen, Tae–Hoon Shin, Aisha A. Aljanahi, Daniel M. Schreeder, Michael Klichinsky, Olga E. Shestova et al. · 2018 · Cell
73. Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
    Wang, Xiaoling, Wang, Yebo, Wu, Xiwei, Wang, Jinhui, Wang, Yingjia, Qiu, Zhaojun, Chang, Tammy, Huang, He, Lin, Ren-Jang, Yee, Jiing-Kuan · 2015 · Nature Biotechnology
74. Small molecules enhance CRISPR genome editing in pluripotent stem cells
    Yu, Chen, Liu, Yanxia, Ma, Tianhua, Liu, Kai, Xu, Shaohua, Zhang, Yu, Liu, Honglei, La Russa, Marie, Xie, Min, Ding, Sheng et al. · 2015 · Cell stem cell
75. Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing
    Naeem, Muhammad, Majeed, Saman, Hoque, Mubasher Zahir, Ahmad, Irshad · 2020 · Cells
76. Editing the epigenome: technologies for programmable transcription and epigenetic modulation
    Thakore, Pratiksha I, Black, Joshua B, Hilton, Isaac B, Gersbach, Charles A · 2016 · Nature Methods
77. Cornerstones of CRISPR–Cas in drug discovery and therapy
    Christof Fellmann, Benjamin G. Gowen, Pei‐Chun Lin, Jennifer A. Doudna, Jacob E. Corn · 2016 · Nature Reviews Drug Discovery
78. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression
    Sung-Hwan Moon, Chun‐Hao Huang, Shauna Lee Houlihan, Kausik Regunath, William A. Freed-Pastor, John P. Morris, Darjus Felix Tschaharganeh, Edward R. Kastenhuber, Anthony M. Barsotti, Rachel Culp‐Hill et al. · 2018 · Cell
79. Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems
    Ahmed A. Gomaa, Heidi E. Klumpe, Michelle L. Luo, Kurt Selle, Rodolphe Barrangou, Chase L. Beisel · 2014 · mBio
80. Crystal Structure of Staphylococcus aureus Cas9
    Hiroshi Nishimasu, Le Cong, Winston X. Yan, F. Ann Ran, Bernd Zetsche, Yinqing Li, Arisa Kurabayashi, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki · 2015 · Cell
81. Progress and prospects in plant genome editing
    Kangquan Yin, Caixia Gao, Jin‐Long Qiu · 2017 · Nature Plants
82. CRISPR in cancer biology and therapy
    Alyna Katti, Bianca Jay Diaz, Christina M. Caragine, Neville E. Sanjana, Lukas E. Dow · 2022 · Nature reviews. Cancer
83. Engineered Cpf1 variants with altered PAM specificities
    Gao, Linyi, Cox, David B T, Yan, Winston X, Manteiga, John C, Schneider, Martin W, Yamano, Takashi, Nishimasu, Hiroshi, Nureki, Osamu, Crosetto, Nicola, Zhang, Feng · 2017 · Nature Biotechnology
84. Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library
    Shiyou Zhu, Wei Li, Jingze Liu, Chen-Hao Chen, Qi Liao, Ping Xu, Han Xu, Tengfei Xiao, Zhongzheng Cao, Jingyu Peng et al. · 2016 · Nature Biotechnology
85. Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
    Holly A. Rees, Alexis C. Komor, Wei-Hsi Yeh, Joana Caetano‐Lopes, Matthew L. Warman, Albert S.B. Edge, David R. Liu · 2017 · Nature Communications
86. Resting zone of the growth plate houses a unique class of skeletal stem cells
    Koji Mizuhashi, Wanida Ono, Yuki Matsushita, Naoko Sakagami, Akira Takahashi, Thomas L. Saunders, Takashi Nagasawa, Henry M. Kronenberg, Noriaki Ono · 2018 · Nature
87. RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
    Jun Whi Song, Dongshan Yang, Jie Xu, Tianqing Zhu, Y. Eugene Chen, Jifeng Zhang · 2016 · Nature Communications
88. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
    Julia Joung, J Engreitz, Silvana Konermann, Omar O. Abudayyeh, Vanessa K. Verdine, François Aguet, Jonathan S. Gootenberg, Neville E. Sanjana, Jason B. Wright, Charles P. Fulco et al. · 2017 · Nature
89. The crystal structure of Cpf1 in complex with CRISPR RNA
    De Dong, Kuan Ren, Xiaolin Qiu, Jianlin Zheng, Minghui Guo, Xiaoyu Guan, Hongnan Liu, Ningning Li, Bailing Zhang, Dai-jun Yang et al. · 2016 · Nature
90. Genome-Editing Technologies: Principles and Applications
    Thomas Gaj, Shannon J. Sirk, Sailan Shui, Jia Liu · 2016 · Cold Spring Harbor Perspectives in Biology
91. sgRNAcas9: A Software Package for Designing CRISPR sgRNA and Evaluating Potential Off-Target Cleavage Sites
    Shengsong Xie, Bin Shen, Chaobao Zhang, Xingxu Huang, Yonglian Zhang · 2014 · PLoS ONE
92. Small molecule–triggered Cas9 protein with improved genome-editing specificity
    Kevin M Davis, Vikram Pattanayak, David B. Thompson, John A. Zuris, David R. Liu · 2015 · Nature Chemical Biology
93. Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae
    Tadas Jakočiūnas, Ida Bonde, Markus J. Herrgård, Scott James Harrison, Mette Kristensen, Lasse Ebdrup Pedersen, Michael Krogh Jensen, Jay D. Keasling · 2015 · Metabolic Engineering
94. Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities
    Jeanne E. van Dongen, Johanna Theodora Wilhelmina Berendsen, Renske D.M. Steenbergen, Rob M.F. Wolthuis, Jan C. T. Eijkel, Loes Irene Segerink · 2020 · Biosensors and Bioelectronics
95. Engineering of CRISPR/Cas9‐mediated potyvirus resistance in transgene‐free Arabidopsis plants
    Douglas Euan Pyott, Emma Sheehan, Attila Molnár · 2016 · Molecular Plant Pathology
96. Rapid modelling of cooperating genetic events in cancer through somatic genome editing
    Francisco J. Sánchez Rivera, Thales Y. Papagiannakopoulos, Rodrigo Romero, Tuomas Tammela, Matthew R. Bauer, Arjun J. Bhutkar, Nikhil S. Joshi, Lakshmipriya Subbaraj, Roderick Terry Bronson, Wen Xue et al. · 2014 · Nature
97. Genome Engineering with CRISPR-Cas9 in the Mosquito Aedes aegypti
    Kathryn E. Kistler, Leslie B. Vosshall, Benjamin John Matthews · 2015 · Cell Reports
98. Expanding the Biologist’s Toolkit with CRISPR-Cas9
    Samuel H. Sternberg, Jennifer A. Doudna · 2015 · Molecular Cell
99. Applications of the CRISPR-Cas9 system in cancer biology
    Sánchez-Rivera, Francisco J., Jacks, Tyler · 2015 · Nature Reviews Cancer
100. Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and <i>piggyBac</i>
     Xie, Fei, Ye, Lin, Chang, Judy C., Beyer, Ashley I., Wang, Jiaming, Muench, Marcus O., Kan, Yuet Wai · 2014 · Genome Research