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Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
Abstract
Satellite cells assure postnatal skeletal muscle growth and repair. Despite extensive studies, their stem cell character remains largely undefined. Using pulse-chase labelling with BrdU to mark the putative stem cell niche, we identify a subpopulation of label-retaining satellite cells during growth and after injury. Strikingly, some of these cells display selective template-DNA strand segregation during mitosis in the muscle fibre in vivo, as well as in culture independent of their niche, indicating that genomic DNA strands are nonequivalent. Furthermore, we demonstrate that the asymmetric cell-fate determinant Numb segregates selectively to one daughter cell during mitosis and before differentiation, suggesting that Numb is associated with self-renewal. Finally, we show that template DNA cosegregates with Numb in label-retaining cells that express the self-renewal marker Pax7. The cosegregation of 'immortal' template DNA strands and their link with the asymmetry apparatus has important implications for stem cell biology and cancer.
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“There is mounting evidence of asymmetric chromosome segregation in stem cells such as MuSCs17,18,129, ISCs20,130,131 and NSCs132.”
From Molecular regulation of stem cell quiescence (2013) · cites this paper as [18]
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Cites
Identification of the haematopoietic stem cell niche and control of the niche size
Zhang, J., Niu, C. S., Ye, L., Huang, H., He, X. C., Tong, W.-G., Ross, J., Haug, J., Johnson, T. J., Feng, J. Q., et al. (2003) · Nature · doi:10.1038/nature02041 · Cited by 2,948
Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors
Ferrari, G., Cusella, G., Angelis, D., Coletta, M., Paolucci, E., Stornaiuolo, A., Cossu, G., & Mavilio, F. (1998) · Science · doi:10.1126/science.279.5356.1528 · Cited by 2,721
Pax7 Is Required for the Specification of Myogenic Satellite Cells
Seale, P., Sabourin, L. A., Girgis-Gabardo, A., Mansouri, A., Gruß, P., & Rudnicki, M. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00066-0 · Cited by 2,345
Socializing with the Neighbors
Fuchs, E. V., Tumbar, T., & Guasch, G. (2004) · Cell · doi:10.1016/s0092-8674(04)00255-7 · Cited by 1,737
Mutation selection and the natural history of cancer
Cairns, J. (1975) · Nature · doi:10.1038/255197a0 · Cited by 1,592
Collins, C. A., Olsen, I., Zammit, P. S., Heslop, L., Petrie, A., Partridge, T. A., & Morgan, J. E. (2005) · Cell · doi:10.1016/j.cell.2005.05.010 · Cited by 1,445
Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Taylor, G., Lehrer, M. S., Jensen, P. J., Sun, T.-T., & Lavker, R. M. (2000) · Cell · doi:10.1016/s0092-8674(00)00050-7 · Cited by 1,070
Expression of Cd34 and Myf5 Defines the Majority of Quiescent Adult Skeletal Muscle Satellite Cells
Beauchamp, J. R., Heslop, L., Yu, D. S., Tajbakhsh, S., Kelly, R. G., Wernig, A., BUCKINGHAM, M. E., Partridge, T. A., & Zammit, P. S. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.6.1221 · Cited by 917
Self-citationConboy, I. M., & Rando, T. A. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00254-x · Cited by 905
Tajbakhsh, S., Rocancourt, D., Cossu, G., & BUCKINGHAM, M. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80189-0 · Cited by 842
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Satellite Cells and the Muscle Stem Cell Niche
Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166
Wilson, A., Laurenti, E., Oser, G., van der Wath, R. C., Blanco-Bose, W., Jaworski, M., Offner, S., Dunant, C. F., Eshkind, L., Bockamp, E., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.048 · Cited by 1,908
Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
Gilbert, P. M., Havenstrite, K. L., Magnusson, K. E. G., Sacco, A., Leonardi, N. A., Kraft, P., Nguyen, N. K., Thrun, S., Lutolf, M. P., & Blau, H. M. (2010) · Science · doi:10.1126/science.1191035 · Cited by 1,587
Asymmetric self-renewal and commitment of satellite stem cells in muscle
Kuang, S., Kuroda, K., Le Grand, F., & Rudnicki, M. A. (2007) · Cell · doi:10.1016/j.cell.2007.03.044 · Cited by 1,449
Building Muscle: Molecular Regulation of MyogenesisPreprint
Bentzinger, C. F., Wang, Y. X., & Rudnicki, M. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008342 · Cited by 1,270
Molecular regulation of stem cell quiescence
Cheung, T. H., & Rando, T. A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3591 · Cited by 1,148
Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration
Sambasivan, R., Yao, R., Kissenpfennig, A., Van Wittenberghe, L., Paldi, A., Gayraud-Morel, B., Guenou, H., Malissen, B., Tajbakhsh, S., & Galy, A. (2011) · Development · doi:10.1242/dev.067587 · Cited by 939
Self-citationSatellite Cells and Skeletal Muscle Regeneration
Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719
Muscle Satellite Cells and Endothelial Cells: Close Neighbors and Privileged Partners
Christov, C., Chrétien, F. C., Abou-Khalil, R., Bassez, G., Vallet, G., Authier, F., Bassaglia, Y., Shinin, V., Tajbakhsh, S., Chazaud, B., et al. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-08-0693 · Cited by 702
Self-citationThe Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold
Zammit, P. S., Partridge, T. A., & Yablonka‐Reuveni, Z. (2006) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.6r6995.2006 · Cited by 684
Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells.
Tedesco, F. S., Dellavalle, A., Díaz-Manera, J., Messina, G., & Cossu, G. (2010) · Journal of Clinical Investigation · doi:10.1172/jci40373 · Cited by 667
Chen, J., Tao, Y., Li, J., Deng, Z., Yan, Z., Xiao, X., & Wang, D.-Z. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.200911036 · Cited by 587
Asymmetric cell division: recent developments and their implications for tumour biology
Knoblich, J. A. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3010 · Cited by 595
Growth and Regeneration of Adult β Cells Does Not Involve Specialized Progenitors
Teta, M., Rankin, M. M., Long, S. Y., Stein, G. M., & Kushner, J. A. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.04.011 · Cited by 551
Skeletal muscle satellite cells and adult myogenesis
Le Grand, F., & Rudnicki, M. A. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.09.012 · Cited by 544
Role of Inflammation in Muscle Homeostasis and Myogenesis
Costamagna, D., Costelli, P., Sampaolesi, M., & Penna, F. (2015) · Mediators of Inflammation · doi:10.1155/2015/805172 · Cited by 547
Dynamics of muscle fibre growth during postnatal mouse development
White, R. B., Biérinx, A.-S., Gnocchi, V. F., & Zammit, P. S. (2010) · BMC Developmental Biology · doi:10.1186/1471-213x-10-21 · Cited by 512
Comparative Study of Injury Models for Studying Muscle Regeneration in Mice
Hardy, D., Besnard, A., Latil, M., Jouvion, G., Briand, D., Thépenier, C., Pascal, Q., Guguin, A., Gayraud-Morel, B., Cavaillon, J., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147198 · Cited by 546
Self-citationRocheteau, P., Gayraud-Morel, B., Siegl-Cachedenier, I., Blasco, M. A., & Tajbakhsh, S. (2012) · Cell · doi:10.1016/j.cell.2011.11.049 · Cited by 510
Self-citationNiche Regulation of Muscle Satellite Cell Self-Renewal and Differentiation
Kuang, S., Gillespie, M. A., & Rudnicki, M. A. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.12.012 · Cited by 507
Intrinsic and extrinsic mechanisms regulating satellite cell function
Dumont, N. A., Wang, Y. X., & Rudnicki, M. A. (2015) · Development · doi:10.1242/dev.114223 · Cited by 491
Mechanisms of asymmetric cell division: flies and worms pave the way
Gönczy, P. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2388 · Cited by 511
BUCKINGHAM, M. E., & Relaix, F. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123438 · Cited by 484
Maintenance of muscle stem-cell quiescence by microRNA-489
Cheung, T. H., Quach, N. L., Charville, G. W., Liu, L., Park, L., Edalati, A., Yoo, B., Hoang, P., & Rando, T. A. (2012) · Nature · doi:10.1038/nature10834 · Cited by 461
Myogenic progenitor cells and skeletal myogenesis in vertebrates
BUCKINGHAM, M. E. (2006) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2006.08.008 · Cited by 452
The central role of muscle stem cells in regenerative failure with aging
Blau, H. M., Cosgrove, B. D., & Ho, A. T. V. (2015) · Nature Medicine · doi:10.1038/nm.3918 · Cited by 437
Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development
Morin, X., & Bellaïche, Y. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.06.012 · Cited by 423
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
Kiel, M. J., He, S., Ashkenazi, R., Gentry, S. N., Teta, M., Kushner, J. A., Jackson, T. L., & Morrison, S. J. (2007) · Nature · doi:10.1038/nature06115 · Cited by 417
Tissue-Specific Stem Cells: Lessons from the Skeletal Muscle Satellite Cell
Brack, A. S., & Rando, T. A. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.04.001 · Cited by 421
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancerPreprint
Neumüller, R. A., & Knoblich, J. A. (2009) · Genes & Development · doi:10.1101/gad.1850809 · Cited by 420
Zanou, N., & Gailly, P. L. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1330-4 · Cited by 378
Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs
Barker, N., Bartfeld, S., & Clevers, H. C. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.11.016 · Cited by 380
The emerging biology of satellite cells and their therapeutic potential
Kuang, S., & Rudnicki, M. A. (2008) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2007.12.004 · Cited by 351
Skeletal muscle stem cells in developmental versus regenerative myogenesis
Tajbakhsh, S. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02158.x · Cited by 333
Self-citationMuscle regeneration: cellular and molecular events.
Karalaki, M., Fili, S., Philippou, Α., & Koutsilieris, M. (2009) · PubMed · Cited by 328
When stem cells grow old: phenotypes and mechanisms of stem cell aging
Schultz, M. B., & Sinclair, D. A. (2016) · Development · doi:10.1242/dev.130633 · Cited by 341
A Population of Myogenic Stem Cells That Survives Skeletal Muscle Aging
Collins, C. A., Zammit, P. S., Ruiz, A. P., Morgan, J. E., & Partridge, T. A. (2007) · Stem Cells · doi:10.1634/stemcells.2006-0372 · Cited by 320
Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease
Almada, A. E., & Wagers, A. J. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.7 · Cited by 322
Regulatory factors and cell populations involved in skeletal muscle regeneration
Broek, R. W. T., Grefte, S., & den Hoff, J. W. V. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22127 · Cited by 315
Olguín, H. C., Yang, Z., Tapscott, S. J., & Olwin, B. B. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200608122 · Cited by 311
Adult stem cells at work: regenerating skeletal muscle
Schmidt, M., Schüler, S. C., Hüttner, S. S., von Eyß, B., & von Maltzahn, J. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03093-6 · Cited by 337
Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism
Steinhauser, M. L., Bailey, A. P., Senyo, S. E., Guillermier, C., Perlstein, T. S., Gould, A. P., Lee, R. T., & Lechène, C. (2012) · Nature · doi:10.1038/nature10734 · Cited by 310
Reciprocal signalling by Notch–Collagen V–CALCR retains muscle stem cells in their niche
Baghdadi, M. B., Castel, D., Machado, L., Fukada, S., Birk, D. E., Relaix, F., Tajbakhsh, S., & Mourikis, P. (2018) · Nature · doi:10.1038/s41586-018-0144-9 · Cited by 309
Self-citationMicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
Hwang, W., Jiang, J., Yang, S.-H., Huang, T. S., Lan, H., Teng, H., Yang, C.-Y., Tsai, Y., Lin, C.-H., Wang, H., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb2910 · Cited by 306
Manifestations and mechanisms of stem cell aging
Liu, L. A., & Rando, T. A. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201010131 · Cited by 318
Windhorst, R. A., Cohen, S. H., Hathi, N. P., McCarthy, P. J., Ryan, R. E., Yan, H., Baldry, I. K., Driver, S. P., Frogel, J. A., Hill, D. T., et al. (2011) · The Astrophysical Journal Supplement Series · doi:10.1088/0067-0049/193/2/27 · Cited by 298
The genetics of vertebrate myogenesis
Bryson‐Richardson, R. J., & Currie, P. D. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2369 · Cited by 303
Conboy, M. J., Karasov, A. O., & Rando, T. A. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050102 · Cited by 287
“25% Triton-X-100, digested with DNAse1 in F-10 medium [8], and immunostained for CldU and IdU as above, using Alexa 488 or Rphycoerythrin anti-rat secondary antibodies, and PE- or FITCconjugated mouse anti-BrdU (IdU) clone B44.”
BackgroundMethodWen, Y., Bi, P., Liu, W., Asakura, A., Keller, C., & Kuang, S. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.06753-11 · Cited by 271
Troy, A., Cadwallader, A. B., Fedorov, Y., Tyner, K., Tanaka, K. K., & Olwin, B. B. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.05.025 · Cited by 268
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Motohashi, N., & Asakura, A. (2014) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2014.00001 · Cited by 262
Pregnancy and the risk of breast cancer
Britt, K. L., Ashworth, A., & Smalley, M. J. (2007) · Endocrine Related Cancer · doi:10.1677/erc-07-0137 · Cited by 416
Telomeres and telomerase in normal and cancer stem cells
Shay, J. W., & Wright, W. E. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.05.026 · Cited by 260
Kelly, K. K., Hall, J. K., Troy, A. A., Cornelison, D., Majka, S. M., & Olwin, B. B. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.01.016 · Cited by 249
Lipid modulation of skeletal muscle mass and function
Lipina, C., & Hundal, H. S. (2017) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12144 · Cited by 247
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches
Conboy, I. M., & Rando, T. A. (2012) · Cell Cycle · doi:10.4161/cc.20437 · Cited by 239
Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease
Feige, P., Brun, C. E., Ritso, M., & Rudnicki, M. A. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.10.006 · Cited by 233
Hernando-Herraez, I., Evano, B., Stubbs, T., Commere, P.-H., Jan Bonder, M., Clark, S., Andrews, S., Tajbakhsh, S., & Reik, W. (2019) · Nature Communications · doi:10.1038/s41467-019-12293-4 · Cited by 236
Self-citationAutocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal
Abou-Khalil, R., Grand, F. L., Pallafacchina, G., Valable, S., Authier, F., Rudnicki, M. A., Gherardi, R. K., Germain, S., Chrétien, F. C., Sotiropoulos, A., et al. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.06.001 · Cited by 236
Mitsiadis, T. A., Barrandon, O., Rochat, A., Barrandon, Y., & Bari, C. D. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.07.027 · Cited by 233
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Day, K. R., Shefer, G., Richardson, J. B., Enikolopov, G., & Yablonka‐Reuveni, Z. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.12.026 · Cited by 222
Juan, A. H., Derfoul, A., Feng, X., Ryall, J. G., Dell’Orso, S., Pasut, A., Zare, H., Simone, J. M., Rudnicki, M. A., & Sartorelli, V. (2011) · Genes & Development · doi:10.1101/gad.2027911 · Cited by 218
Immortality of cell lines: challenges and advantages of establishment
Irfan Maqsood, M., Matin, M. M., Bahrami, A. R., & Ghasroldasht, M. M. (2013) · Cell Biology International · doi:10.1002/cbin.10137 · Cited by 217
Imaging stem-cell-driven regeneration in mammals
Schroeder, T. (2008) · Nature · doi:10.1038/nature07043 · Cited by 206
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Zammit, P. S. (2008) · Journal of Cell Science · doi:10.1242/jcs.019661 · Cited by 213
Lying low but ready for action: the quiescent muscle satellite cell
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Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation
Liu, W., Wen, Y., Bi, P., Lai, X., Liu, X., Liu, X., & Kuang, S. (2012) · Development · doi:10.1242/dev.079665 · Cited by 198
Organelle positioning and cell polarity
Bornens, M. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2524 · Cited by 191
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González, C. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2103 · Cited by 196
The multiple functions of Numb
Gulino, A., Marcotullio, L. D., & Screpanti, I. (2009) · Experimental Cell Research · doi:10.1016/j.yexcr.2009.11.017 · Cited by 192
Recent Progress on Tissue-Resident Adult Stem Cell Biology and Their Therapeutic Implications
Mimeault, M., & Batra, S. K. (2008) · Stem Cell Reviews and Reports · doi:10.1007/s12015-008-9008-2 · Cited by 194
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Potten, C. S., Gândara, R., Mahida, Y., Loeffler, M., & Wright, N. A. (2009) · Cell Proliferation · doi:10.1111/j.1365-2184.2009.00642.x · Cited by 189
3D Timelapse Analysis of Muscle Satellite Cell Motility
Siegel, A. L., Atchison, K., Fisher, K. E., Davis, G. E., & Cornelison, D. (2009) · Stem Cells · doi:10.1002/stem.178 · Cited by 184
Snippert, H. J. G., & Clevers, H. C. (2011) · EMBO Reports · doi:10.1038/embor.2010.216 · Cited by 184
Chang, N. C., & Rudnicki, M. A. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-416022-4.00006-8 · Cited by 190
Attributes of adult stem cells
Alison, M., & Islam, S. (2008) · The Journal of Pathology · doi:10.1002/path.2498 · Cited by 182
Heterogeneity in the muscle satellite cell population
Biressi, S., & Rando, T. A. (2010) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2010.09.003 · Cited by 168
Allan, A. L., Vantyghem, S. A., Tuck, A. B., & Chambers, A. F. (2007) · Breast Disease · doi:10.3233/bd-2007-26108 · Cited by 167
Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer
Ge, Y., & Fuchs, E. V. (2018) · Nature Reviews Genetics · doi:10.1038/nrg.2018.9 · Cited by 172
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Kubota, Y., Takubo, K., & Suda, T. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.11.086 · Cited by 172
Melanoma Stem Cells: The Dark Seed of Melanoma
Zabierowski, S. E., & Herlyn, M. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.5465 · Cited by 161
Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis
Tierney, M. T., & Sacco, A. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.02.004 · Cited by 151
“Cell adhesion regulates DNA segregation and satellite cell fate during asymmetric division in situ and in vitro [35,51,52]; thus, monitoring satellite cell division dynamics within their native microenvironment is of critical importance.”
BackgroundChakkalakal, J. V., Christensen, J., Xiang, W., Tierney, M. T., Boscolo, F. S., Sacco, A., & Brack, A. S. (2014) · Development · doi:10.1242/dev.100842 · Cited by 148
NUMB-ing down cancer by more than just a NOTCH
Pece, S., Confalonieri, S., Romano, P. R., & Fiore, P. P. D. (2010) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2010.10.001 · Cited by 146
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Gurevich, D., Nguyen, P. D., Siegel, A. L., Ehrlich, O., Sonntag, C., Phan, J. M. N., Berger, S., Ratnayake, D., Hersey, L., Berger, J., et al. (2016) · Science · doi:10.1126/science.aad9969 · Cited by 146
Skeletal muscle stem cell birth and properties
Sambasivan, R., & Tajbakhsh, S. (2007) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2007.09.013 · Cited by 143
Self-citationDefining the transcriptional signature of skeletal muscle stem cells1,2
Yablonka‐Reuveni, Z., Day, K. R., Vine, A. L., & Shefer, G. (2007) · Journal of Animal Science · doi:10.2527/jas.2007-0473 · Cited by 141
Cosgrove, B. D., Sacco, A., Gilbert, P. M., & Blau, H. M. (2009) · Differentiation · doi:10.1016/j.diff.2009.08.004 · Cited by 141
Skeletal muscle stem cells in comfort and stress
Evano, B., & Tajbakhsh, S. (2018) · npj Regenerative Medicine · doi:10.1038/s41536-018-0062-3 · Cited by 144
Self-citationMitochondria as a Potential Regulator of Myogenesis
Wagatsuma, A., & Sakuma, K. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/593267 · Cited by 141
Duddy, W. J., Duguez, S., Johnston, H., Cohen, T. V., Phadke, A., Gordish‐Dressman, H., Nagaraju, K., Gnocchi, V. F., Low, S., & Partridge, T. A. (2015) · Skeletal Muscle · doi:10.1186/s13395-015-0041-y · Cited by 136
Control of the adaptive response of the heart to stress via the Notch1 receptor pathway
Croquelois, A., Domenighetti, A. A., Nemir, M., Lepore, M. G., Rosenblatt‐Velin, N., Radtke, F., & Pedrazzini, T. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20081427 · Cited by 133
Metabolism and the Control of Cell Fate Decisions and Stem Cell Renewal
Ito, K., & Ito, K. (2016) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-111315-125134 · Cited by 143
Microenvironmental modulation of asymmetric cell division in human lung cancer cells
Pine, S. R., Ryan, B. M., Varticovski, L., Robles, A. I., & Harris, C. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909390107 · Cited by 138
Syndecan-3 and Notch cooperate in regulating adult myogenesis
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Metadata
- Authors
- Shinin, V., Gayraud-Morel, B., Gomès, D., & Tajbakhsh, S.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Tajbakhsh, Shahragim
- Venue
- Nature Cell Biology
- Published
- 2006-06-25
- Volume
- 8
- Issue
- 7
- Pages
- 677-682
- ISSN
- 1465-7392 (ISSN-L)
- 1476-4679
- OpenAlex
- W2091757969
- Cited by
- 504
- References
- 51
- Citations by year
- 2026: 7 · 2025: 5 · 2024: 12 · 2023: 8 · 2022: 11 · 2021: 17 · 2020: 11 · 2019: 16 · 2018: 17 · 2017: 15 · 2016: 23 · 2015: 29 · 2014: 28 · 2013: 47 · 2012: 52
- FWCI
- 18.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- satellite cells, asymmetric cell division, Numb, label-retaining cells, stem cell self-renewal, Pax7, skeletal muscle regeneration, mitosis, stem cell niche
- MeSH terms
- Animals, Bromodeoxyuridine, Cell Transformation, Neoplastic, Cells, Cultured, DNA Replication, DNA, Single-Stranded, Membrane Proteins, Mice, Transgenic, Mitosis, Nerve Tissue Proteins, Regeneration, Muscle, Skeletal, Cell Lineage, Satellite Cells, Skeletal Muscle, Mice, PAX7 Transcription Factor
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