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Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
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“After using ZFNs to target a construct containing a drug selection cassette and the sequences to correct the polymorphic mutation, the selection cassette was seamlessly excised via transposase acting on flanking PiggyBac transposons [96].”
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Metadata
- Authors
- Zimmermann, W.-H., Melnychenko, I., Wasmeier, G., Didié, M., Naito, H., Nixdorff, U., Hess, A., Budinsky, L., Brune, K., Michaelis, B., Dhein, S., Schwoerer, A., Ehmke, H., & Eschenhagen, T.
- Venue
- Nature Medicine
- Published
- 2006-04
- Volume
- 12
- Issue
- 4
- Pages
- 452-458
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2096237299
- Cited by
- 993
- References
- 1
- FWCI
- 42.08
- Type
- journal article
- Language
- en
- Open access
- closed
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