MicroRNAs in the p53 network: micromanagement of tumour suppression

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A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

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A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells

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Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

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Modes of p53 regulation.

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Roles for MicroRNAs in Conferring Robustness to Biological Processes

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The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

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Transcriptional Activation of miR-34a Contributes to p53-Mediated Apoptosis

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miR-34a repression of SIRT1 regulates apoptosis

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The miR-34 family in cancer and apoptosis

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Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

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MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

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Modulation of microRNA processing by p53

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MicroRNAs in metabolism and metabolic disorders

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p53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes

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Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation

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A microRNA DNA methylation signature for human cancer metastasis

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The microcosmos of cancer

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Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

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The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

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MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

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Differential Regulation of microRNAs by p53 Revealed by Massively Parallel Sequencing: miR-34a is a p53 Target That Induces Apoptosis and G1-arrest

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The Lin28/let-7 Axis Regulates Glucose Metabolism

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Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

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Snail blocks the cell cycle and confers resistance to cell deathPreprint

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MicroRNA functions in stress responses

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Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?

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The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

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p53 represses c-Myc through induction of the tumor suppressor miR-145

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MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

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Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

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p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

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DICER1 Mutations in Familial Pleuropulmonary Blastoma

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Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue

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Mediation of c-Myc-Induced Apoptosis by p53

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p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

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Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

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MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

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Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice

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A MicroRNA Targeting Dicer for Metastasis Control

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MicroRNA-125b is a novel negative regulator of p53Preprint

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MicroRNA-34b and MicroRNA-34c Are Targets of p53 and Cooperate in Control of Cell Proliferation and Adhesion-Independent Growth

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miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

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The interplay between MYC and HIF in cancer

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miR-29 miRNAs activate p53 by targeting p85α and CDC42

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Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

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Reduced expression of Dicer associated with poor prognosis in lung cancer patients

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The expanding universe of p53 targets

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MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

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p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

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p53 Enters the MicroRNA World

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p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

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A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition

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Dicer1 functions as a haploinsufficient tumor suppressorPreprint

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The 14-3-3 cancer connection

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P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

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MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

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miR-34 miRNAs provide a barrier for somatic cell reprogramming

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miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

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The ZEB1/miR‐200 feedback loop controls Notch signalling in cancer cells

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Coordinated epigenetic repression of the miR‐200 family and miR‐205 in invasive bladder cancer

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miR‐15a and miR‐16‐1 down‐regulation in pituitary adenomas

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Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

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Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215

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A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

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Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition

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p53 connects tumorigenesis and reprogramming to pluripotency

Tàpia, N., & Schöler, H. R. (2010) · The Journal of Experimental Medicine · doi:10.1084/jem.20101866 · Cited by 71

A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer

Li, N., Kaur, S., Greshock, J., Lassus, H., Zhong, X.-M., Wang, Y., Leminen, A., Shao, Z.-M., Hu, X., Liang, S., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-2484 · Cited by 67

Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1

Ravi, A., Gurtan, A. M., Kumar, M. S., Bhutkar, A. J., Chin, C., Lu, V., Lees, J. A., Jacks, T., & Sharp, P. A. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.04.037 · Cited by 66

Hsa-miR-34c suppresses growth and invasion of human laryngeal carcinoma cells via targeting c-Met

Cai (2010) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000378 · Cited by 63

MicroRNA-34b/c suppresses uveal melanoma cell proliferation and migration through multiple targets.

Dong, F., & Lou, D. (2012) · PubMed Central · Cited by 62

To repress or not to repress: This is the guardian's question

Rinn, J. L., & Huarte, M. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.04.002 · Cited by 60

Genetic and epigenetic association studies suggest a role of microRNA biogenesis gene exportin-5 (XPO5) in breast tumorigenesis.

Leaderer, D., Hoffman, A. E., Zheng, T., Fu, A., Weidhaas, J. B., Paranjape, T., & Zhu, Y. (2011) · Europe PMC (PubMed Central) · Cited by 60

Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks of prognostic relevance

Rücker, F. G., Russ, A. C., Cocciardi, S., Kett, H., Schlenk, R. F., Botzenhardt, U., Langer, C., Krauter, J., Fröhling, S., Schlegelberger, B., et al. (2012) · Leukemia · doi:10.1038/leu.2012.208 · Cited by 49

The miR‐15a‐miR‐16‐1 locus is homozygously deleted in a subset of prostate cancers

Porkka, K. P., Ogg, E.-L., Saramäki, O. R., Vessella, R. L., Pukkila, H., Lähdesmäki, H. J., van Weerden, W. M., Wolf, M., Kallioniemi, O., Jenster, G. W., et al. (2011) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20873 · Cited by 47

BM-ca is a newly defined type I/II anti-CD20 monoclonal antibody with unique biological properties

Nishida (2010) · International Journal of Oncology · doi:10.3892/ijo.2010.864 · Cited by 45

MiR-34 and SNAIL: Another double-negative feedback loop controlling cellular plasticity/EMT governed by p53

Brabletz, T. (2012) · Cell Cycle · doi:10.4161/cc.11.2.18900 · Cited by 44

Epigenetic Alteration of DNA in Mucosal Wash Fluid Predicts Invasiveness of Colorectal Tumors

Kamimae, S., Yamamoto, E., Yamano, H., Nojima, M., Suzuki, H., Ashida, M., Hatahira, T., Satô, A., Kimura, T., Yoshikawa, K., et al. (2011) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-10-0214 · Cited by 41

Erratum: p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

Chang, C.-J., Chao, C.-H., Xia, W., Yang, J.-Y., Xiong, Y., Li, C.-W., Yu, W.-H., Rehman, S. K., Hsu, J. L., Lee, H., et al. (2011) · Nature Cell Biology · doi:10.1038/ncb2401 · Cited by 15

MicroRNA and cancer

Jansson, M., & Lund, A. H. (2012) · Molecular Oncology · doi:10.1016/j.molonc.2012.09.006 · Cited by 1,150

P53 in survival, death and metabolic health: a lifeguard with a licence to kill.

Kruiswijk, F., Labuschagne, C. F., & Vousden, K. H. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm4007 · Cited by 1,080

Census and evaluation of p53 target genes

Fischer, M. (2017) · Oncogene · doi:10.1038/onc.2016.502 · Cited by 971

MicroRNA-34a regulates cardiac ageing and function.

Boon, R. A., Iekushi, K., Lechner, S., Seeger, T., Fischer, A., Heydt, S., Kaluza, D., Tréguer, K., Carmona, G., Bonauer, A., et al. (2013) · Nature · doi:10.1038/nature11919 · Cited by 821

Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting

Borrero, L. J. H., & El‐Deiry, W. S. (2021) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2021.188556 · Cited by 805

The P53/microRNA network: A potential tumor suppressor with a role in anticancer therapy

Sargolzaei, J., Etemadi, T., & Alyasin, A. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105179 · Cited by 42

Genetic Networks Lead and Follow Tumor Development: MicroRNA Regulation of Cell Cycle and Apoptosis in the p53 Pathways

Otsuka, K., & Ochiya, T. (2014) · BioMed Research International · doi:10.1155/2014/749724 · Cited by 42

MicroRNA Control of p53

Liu, J., Zhang, C., Zhao, Y., & Feng, Z. (2016) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25609 · Cited by 143

Analysis of the p53/microRNA Network in Cancer

Kaller, M., Hünten, S., Siemens, H., & Hermeking, H. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-08356-3_7 · Cited by 12

MicroRNAs, wild-type and mutant p53: More questions than answers

Jones, M. F., & Lal, A. (2012) · RNA Biology · doi:10.4161/rna.20146 · Cited by 55