The pathophysiology of defective proteostasis in the hypothalamus — from obesity to ageing

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Hypothalamic C2-domain protein involved in MC4R trafficking and control of energy balance

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Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues

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Primary aldosteronism is associated with decreased low‐density and high‐density lipoprotein particle concentrations and increased GlycA, a pro‐inflammatory glycoprotein biomarker

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Downregulation of HIF complex in the hypothalamus exacerbates diet-induced obesity

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Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders

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PYY-mediated appetite control and obesity alleviation through short-chain fatty acid–driven gut-brain axis modulation by Lacticaseibacillus rhamnosus HF01 isolated from Qula

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Microglia–Neuron Crosstalk in Obesity: Melodious Interaction or Kiss of Death?

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Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

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Microglia in Central Control of Metabolism

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Sleeve Gastrectomy Rescuing the Altered Functional Connectivity of Lateral but Not Medial Hypothalamus in Subjects with Obesity

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Hypothalamic neuronal cellular and subcellular abnormalities in experimental obesity

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The timeline of neuronal and glial alterations in experimental obesity

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The hypothalamus as the central regulator of energy balance and its impact on current and future obesity treatments

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Arcuate Nucleus Overexpression of NHLH2 Reduces Body Mass and Attenuates Obesity-Associated Anxiety/Depression-like Behavior

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Sex-dependent effect on mitochondrial and oxidative stress parameters in the hypothalamus induced by prepubertal stress and access to high fat diet

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An Inflammatory Clock Predicts Multi-morbidity, Immunosenescence and Cardiovascular Aging in HumansPreprint

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Hypothalamic expression of the atypical chemokine receptor ACKR2 is involved in the systemic regulation of glucose tolerance

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Proteostasis signatures in human diseases

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DNA Methylation in the Hypothalamic Feeding Center and Obesity

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Risk of Fat Mass- and Obesity-Associated Gene-Dependent Obesogenic Programming by Formula Feeding Compared to Breastfeeding

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Brain‐Derived Neurotrophic Factor ( BDNF ) and Sex Differences in Metabolic Regulation

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CD1 is involved in diet-induced hypothalamic inflammation in obesity

Bombassaro, B., Ramalho, A. F. S., Fioravante, M., Solon, C., Nogueira, G. A. S., Nogueira, P. A. S., Gaspar, R. S., Ropelle, E. R., & Velloso, L. A. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.01.011 · Cited by 8 · see citing works

Effects of Amifostine Pre-treatment on miRNA, lncRNA, and mRNA Profiles in the Hypothalamus of Mice Exposed to 60Co Gamma Radiation

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High-fiber-diet-related metabolites improve neurodegenerative symptoms in patients with obesity with diabetes mellitus by modulating the hippocampal–hypothalamic endocrine axis

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Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice

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Hypothalamic circuits and aging: keeping the circadian clock updated

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CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunctionPreprint

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Hormones in aging

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Mécanismes, facteurs de risque et stratégies thérapeutiques dans la maladie d’Alzheimer

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TLR4-interactor with leucine-rich repeats (TRIL) is involved in diet-induced hypothalamic inflammation

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Ontogenetic Changes in the Expression of the Lin28 Protein in the Rat Hypothalamic Tuberal Nuclei

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Acute physical exercise increases APPL 1/ PI 3K signaling in the hypothalamus of lean mice

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Inhibition of Crif1 protects fatty acid-induced POMC neuron-like cell-line damage by increasing CPT-1 function

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(m-CF3-PhSe)2 counteracts metabolic disturbances and hypothalamic inflammation in a lifestyle rodent model

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Phenethyl isothiocyanate ameliorates high-fat diet-induced obesity by antagonizing hypothalamic leptin resistance

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Age-related shifts in ghrelin responsiveness of dorsomedial and ventromedial hypothalamic neurons in rats

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Environmental and Physiological Cues on the Hypothalamus During Aging

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Altered olfaction, obesity, and glycosylated hemoglobin; Indicators of accelerated ageing in apparently healthy, Pakistan's young aged population

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We could be better if we ate better

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POMC-specific knockdown of Tril reduces body adiposity and increases hypothalamic leptin responsivenessPreprint

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Genetic Syndromes of Hypothalamic Dysfunction

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Efeito da interleucina 17 na regulação hipotalâmica da homeostase energética

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Nutritional factors regulating behavior and biological clocks

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A regulação da autofagia mediada por chaperonas no hipotálamo em resposta ao excesso de lipídeos

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A proteína CD1 medeia a inflamação hipotalâmica na obesidade induzida por dieta

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Avaliação do papel do TGF-ß1 e da microglia na resposta inflamatória hipotalâmica induzida por ácidos graxos saturados

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O fator de transcrição CREB hipotalâmico é regulado por palmitato e dieta hiperlipídica

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Fundamentos Neuroanatómicos y Neurofisiológicos de la Región Hipotalámica para su Tratamiento Neuroquirúrgico Estereotáctico. Su importancia para la terapéutica de la obesidad mórbida refractaria.

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CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunction

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CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunctionPreprint

Mendes, N. F., Zanesco, A. M., de Aguiar, C. F., Rodrigues-Luiz, G. F., da Silva, D. C., Campos, J. F., Câmara, N. O. S., Moraes‐Vieira, P. M., ARAUJO, E. P. D., & Velloso, L. A. (2024) · eLife · doi:10.7554/elife.95044.1

CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunctionPreprint

Mendes, N. F., Zanesco, A. M., de Aguiar, C. F., Rodrigues-Luiz, G. F., da Silva, D. C., Campos, J. F., Câmara, N. O. S., Moraes‐Vieira, P. M., ARAUJO, E. P. D., & Velloso, L. A. (2024) · eLife · doi:10.7554/elife.95044.2

Hsp60 and pathophysiology of the neuroendocrine system

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Additional file 1 of Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis

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Hypothalamic Dysfunction in Obesity and Metabolic Disorders

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Defective Regulation of the Ubiquitin/Proteasome System in the Hypothalamus of Obese Male Mice

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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

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The ageing hypothalamus: impact on neuronal and glial cells that control energy homeostasis

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