Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2

Slamon, D. J., Leyland-Jones, B., Shak, S., Fuchs, H., Paton, V., Bajamonde, A., Fleming, T., Eiermann, W., Wolter, J., Pegram, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200103153441101 · Cited by 11,500

Wnt proteins are lipid-modified and can act as stem cell growth factors

Willert, K., Brown, J. D., Danenberg, E., Duncan, A. W., Weissman, I. L., Reya, T., Yates, J. R., & Nusse, R. (2003) · Nature · doi:10.1038/nature01611 · Cited by 2,257

Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling

Mao, B., Wu, W., Davidson, G., Marhold, J., Li, M., Mechler, B. M., Delius, H., Hoppe, D., Stannek, P., Walter, C., et al. (2002) · Nature · doi:10.1038/nature756 · Cited by 1,038

Clathrin

Kirchhausen, T. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.699 · Cited by 560

Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Chen, W., ten Berge, D., Brown, J., Ahn, S., Hu, L. A., Miller, W. E., Caron, M. G., Barak, L. S., Nusse, R., & Lefkowitz, R. J. (2003) · Science · doi:10.1126/science.1082808 · Cited by 334

Ligand-dependent and -independent Transforming Growth Factor-β Receptor Recycling Regulated by Clathrin-mediated Endocytosis and Rab11

Mitchell, H., Choudhury, A., Pagano, R. E., & Leof, E. B. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-03-0245 · Cited by 215

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

Dyson, S., & Gurdon, J. B. (1998) · Cell · doi:10.1016/s0092-8674(00)81185-x · Cited by 204

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Blanco, E., Shen, H., & Ferrari, M. (2015) · Nature Biotechnology · doi:10.1038/nbt.3330 · Cited by 7,002

Microglial interactions with synapses are modulated by visual experience

Tremblay, M.-È., Lowery, R. L., & Majewska, A. K. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000527 · Cited by 1,542

The Role of Microglia in the Healthy Brain: Figure 1.

Tremblay, M.-È., Stevens, B., Sierra, A., Wake, H., Bessis, A., & Nimmerjahn, A. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4158-11.2011 · Cited by 992

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

Giannotta, M., Trani, M., & Dejana, E. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.08.020 · Cited by 854

TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019

Dewidar, B., Meyer, C., Dooley, S., & Meindl-Beinker, A. N. (2019) · Cells · doi:10.3390/cells8111419 · Cited by 837

Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

Chowdhury, S., Shepherd, J. D., Okuno, H., Lyford, G., Petralia, R. S., Plath, N., Kuhl, D., Huganir, R. L., & Worley, P. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.08.033 · Cited by 792

Specificity, versatility, and control of TGF-β family signaling

Derynck, R., & Budi, E. H. (2019) · Science Signaling · doi:10.1126/scisignal.aav5183 · Cited by 785

Mapk signal specificity: The right place at the right time

Murphy, L. O., & Blenis, J. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.03.009 · Cited by 707

Clathrin-independent pathways do not contribute significantly to endocytic flux

Bitsikas, V., Corrêa, I. R., & Nichols, B. J. (2014) · eLife · doi:10.7554/elife.03970 · Cited by 199

Protein delivery into cells using inorganic nanoparticle–protein supramolecular assemblies

Scaletti, F., Hardie, J., Lee, Y.-W., Luther, D. C., Ray, M., & Rotello, V. M. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00008e · Cited by 208

Leishmania GP63 Alters Host Signaling Through Cleavage-Activated Protein Tyrosine Phosphatases

Gomez, M. A., Contreras, I., Hallé, M., Tremblay, M. L., McMaster, R. W., & Olivier, M. (2009) · Science Signaling · doi:10.1126/scisignal.2000213 · Cited by 206

Epithelial cell–cell junctions and plasma membrane domains

Giepmans, B. N. G., & van IJzendoorn, S. C. D. (2009) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.07.015 · Cited by 170

Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release

Langelier, C., von Schwedler, U. K., Fisher, R. D., De Domenico, I., White, P. L., Hill, C. P., Kaplan, J., Ward, D., & Sundquist, W. I. (2006) · Journal of Virology · doi:10.1128/jvi.01049-06 · Cited by 166

Molecular basis for SH3 domain regulation of F-BAR–mediated membrane deformation

Rao, Y., Ma, Q., Vahedi-Faridi, A., Sundborger, A., Pechstein, A., Puchkov, D., Luo, L., Shupliakov, O., Saenger, W., & Haucke, V. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003478107 · Cited by 149

Phosphoinositide regulation of clathrin-mediated endocytosis

Haucke, V. (2005) · Biochemical Society Transactions · doi:10.1042/bst0331285 · Cited by 140

Spine microdomains for postsynaptic signaling and plasticity

Newpher, T. M., & Ehlers, M. D. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.02.004 · Cited by 140

The endocytic pathway in microglia during health, aging and Alzheimer’s disease

Solé-Domènech, S., Cruz, D. L., Capetillo-Zarate, E., & Maxfield, F. R. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.07.002 · Cited by 133

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

Siebold, C., Yamashita, T., Monnier, P. P., Mueller, B. K., & Pasterkamp, R. J. (2017) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.11.009 · Cited by 118

Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein

Healey, E. G., Bishop, B., Elegheert, J., Bell, C. H., Padilla-Parra, S., & Siebold, C. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3016 · Cited by 112

Influence of protein corona and caveolae-mediated endocytosis on nanoparticle uptake and transcytosis

Ho, Y. T., Kamm, R. D., & Kah, J. C. Y. (2018) · Nanoscale · doi:10.1039/c8nr02393j · Cited by 102

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

Yue, S., Tang, L.-Y., Tang, Y., Tang, Y., Shen, Q.-H., Ding, J., Chen, Y., Zhang, Z., Yu, T.-T., Zhang, Y. E., et al. (2014) · eLife · doi:10.7554/elife.02555 · Cited by 94

RAB-10 Regulates Glutamate Receptor Recycling in a Cholesterol-dependent Endocytosis Pathway

Glodowski, D. R., Chen, C. C.-H., Schaefer, H., Grant, B. D., & Rongo, C. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-05-0486 · Cited by 86

Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance

Bahl, S., & Seto, E. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03599-4 · Cited by 82

Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor

Khan, Z., Vijayakumar, S., de la Torre, T. V., Rotolo, S., & Bafico, A. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00773-07 · Cited by 73

KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling

Schou, K. B., Mogensen, J. B., Morthorst, S. K., Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., et al. (2017) · Nature Communications · doi:10.1038/ncomms14177 · Cited by 72

Recycling to the Plasma Membrane is Delayed in EHD1 Knockout Mice

Rapaport, D., Auerbach, W., Naslavsky, N., Pasmanik‐Chor, M., Galperin, E., Fein, A., Caplan, S., Joyner, A. L., & Horowitz, M. (2006) · Traffic · doi:10.1111/j.1600-0854.2005.00359.x · Cited by 67

Spatio-temporal Model of Endogenous ROS and Raft-Dependent WNT/Beta-Catenin Signaling Driving Cell Fate Commitment in Human Neural Progenitor Cells

Haack, F., Lemcke, H., Ewald, R., Rharass, T., & Uhrmacher, A. M. (2015) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1004106 · Cited by 66

Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A

Narazaki, M., Segarra, M., & Tosato, G. (2008) · Blood · doi:10.1182/blood-2007-09-112474 · Cited by 59

Syndecan-1 mediates internalization of apoE-VLDL through a low density lipoprotein receptor-related protein (LRP)-independent, non-clathrin-mediated pathway

Wilsie, L. C., Gonzales, A. M., & Orlando, R. A. (2006) · Lipids in Health and Disease · doi:10.1186/1476-511x-5-23 · Cited by 60

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

Lissanu Deribe, Y., Wild, P., Chandrashaker, A., Curak, J., Schmidt, M. H. H., Kalaidzidis, Y., Milutinovic, N., Kratchmarova, I., Buerkle, L., Fetchko, M. J., et al. (2009) · Science Signaling · doi:10.1126/scisignal.2000576 · Cited by 60

FRET Imaging Reveals Different Cellular Entry Routes of Self-Assembled and Disulfide Bonded Polymeric Micelles

Lee, S.-Y., Tyler, J. Y., Kim, S., Park, K., & Cheng, J.-X. (2013) · Molecular Pharmaceutics · doi:10.1021/mp4003333 · Cited by 59

Renin-angiotensin system in human coronavirus pathogenesis

Wevers, B. A., & Hoek, L. V. D. (2010) · Future Virology · doi:10.2217/fvl.10.4 · Cited by 51

Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development

Bhattacharyya, S., Rainey, M. A., Arya, P., Mohapatra, B. C., Mushtaq, I., Dutta, S., George, M., Storck, M. D., McComb, R. D., Muirhead, D., et al. (2016) · Scientific Reports · doi:10.1038/srep20727 · Cited by 36

Analysis of SRC Oncogenic Signaling in Colorectal Cancer by Stable Isotope Labeling with Heavy Amino Acids in Mouse Xenografts

Sirvent, A., Vigy, O., Orsetti, B., Urbach, S., & Roche, S. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m112.018168 · Cited by 33

Phosphoinositides: Roles in the Development of Microglial-Mediated Neuroinflammation and Neurodegeneration

Ernest James Phillips, T., & Maguire, E. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.652593 · Cited by 33

Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking

Yoshioka, K. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200835 · Cited by 31

Major histocompatibility complex class I downregulation induced by equine herpesvirus type 1 pUL56 is through dynamin-dependent endocytosis.

Huang, T., Lehmann, M. J., Said, A., Ma, G., & Osterrieder, N. (2014) · Journal of Virology · doi:10.1128/jvi.02079-14 · Cited by 24

Exploring the mechanistic and temporal regulation of LRP6 endocytosis in canonical WNT signaling

Haack, F., Budde, K., & Uhrmacher, A. M. (2020) · Journal of Cell Science · doi:10.1242/jcs.243675 · Cited by 18