Cited by 723Influenza Virus Research StudiesRespiratory viral infections researchPneumonia and Respiratory Infections

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The co-pathogenesis of influenza viruses with bacteria in the lung.

McCullers, Jonathan A.·2014·Nature Reviews Microbiology

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Abstract

Concern that a highly pathogenic virus might cause the next influenza pandemic has spurred recent research into influenza and its complications. Bacterial superinfection in the lungs of people suffering from influenza is a key element that promotes severe disease and mortality. This co-pathogenesis is characterized by complex interactions between co-infecting pathogens and the host, leading to the disruption of physical barriers, dysregulation of immune responses and delays in a return to homeostasis. The net effect of this cascade can be the outgrowth of the pathogens, immune-mediated pathology and increased morbidity. In this Review, advances in our understanding of the underlying mechanisms are discussed, and the key questions that will drive the field forwards are articulated.

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Evolution and ecology of influenza A viruses
Webster, R. G., Bean, W. J., Gorman, O. T., Chambers, T. M., & Kawaoka, Y. (1992) · Microbiological Reviews · doi:10.1128/mr.56.1.152-179.1992 · Cited by 4,739
Tissue Destruction by Neutrophils
Epstein, F. H., & Weiss, S. J. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902093200606 · Cited by 3,950
Tissue Destruction by Neutrophils
(1989) · New England Journal of Medicine · doi:10.1056/nejm198908033210513 · Cited by 3,634
Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans
Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0903810 · Cited by 3,063
Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness
Morens, D. M., Taubenberger, J. K., & Fauci, A. S. (2008) · The Journal of Infectious Diseases · doi:10.1086/591708 · Cited by 1,625
Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
Gillet, Y., Issartel, B., Vanhems, P., Fournet, J.-C., Lina, G., Bes, M., Vandenesch, F., Piémont, Y., Brousse, N., Floret, D., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07877-7 · Cited by 1,514
Microbiota regulates immune defense against respiratory tract influenza A virus infection
Ichinohe, T., Pang, I. K., Kumamoto, Y., Peaper, D. R., Ho, J. H., Murray, T. S., & Iwasaki, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019378108 · Cited by 1,502
Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada
Kumar, A. (2009) · JAMA · doi:10.1001/jama.2009.1496 · Cited by 1,425
Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury
Imai, Y., Kuba, K., Neely, G. G., Yaghubian-Malhami, R., Perkmann, T., van Loo, G., Ermolaeva, M., Veldhuizen, R., Leung, Y. H. C., Wang, H., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.043 · Cited by 1,356
Inflammatory cells during wound repair: the good, the bad and the ugly
Martin, P., & Leibovich, S. J. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.09.002 · Cited by 1,340
Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study.
Dawood, F. S., Iuliano, A., Reed, C., Meltzer, M., Shay, D., Cheng, P.-Y., Bandaranayake, D., Breiman, R., Brooks, W. A., Buchy, P., et al. (2012) · Lancet. Infectious Diseases (Print) · doi:10.1016/s1473-3099(12)70121-4 · Cited by 1,294
The multifunctional NS1 protein of influenza A viruses
Hale, B. G., Randall, R. E., Ortı́n, J., & Jackson, D. (2008) · Journal of General Virology · doi:10.1099/vir.0.2008/004606-0 · Cited by 1,078
A novel influenza A virus mitochondrial protein that induces cell death
Chen, W., Calvo, P. A., Malide, D. A., Gibbs, J. S., Schubert, U., Bačík, I., Basta, S., O’Neill, R. E., Schickli, J. H., Palese, P., et al. (2001) · Nature Medicine · doi:10.1038/nm1201-1306 · Cited by 1,037
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
Abt, M. C., Osborne, L. C., Monticelli, L. A., Doering, T. A., Alenghat, T., Sonnenberg, G. F., Paley, M. A., Antenus, M., Williams, K. L., Erikson, J., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.04.011 · Cited by 993
Surface protein adhesins of Staphylococcus aureus
Foster, T. J., & Höök, M. (1998) · Trends in Microbiology · doi:10.1016/s0966-842x(98)01400-0 · Cited by 985
Insights into the Interaction between Influenza Virus and Pneumococcus
McCullers, J. A. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00058-05 · Cited by 846
Self-citation
Critically Ill patients with 2009 influenza A(H1N1) in Mexico
Domínguez-Cherit, G. (2009) · JAMA · doi:10.1001/jama.2009.1536 · Cited by 840
Epidemiology and Clinical Characteristics of Community-Acquired Pneumonia in Hospitalized Children
Michelow, I. C., Olsen, K. D., Lozano, J., Rollins, N. K., Duffy, L. B., Ziegler, T. T., Kauppila, J., Leinonen, M., & McCracken, G. H. (2004) · PEDIATRICS · doi:10.1542/peds.113.4.701 · Cited by 709
Textbook of Influenza
(2013) · Wiley eBooks · doi:10.1002/9781118636817 · Cited by 665
Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection
Sun, K., & Metzger, D. W. (2008) · Nature Medicine · doi:10.1038/nm1765 · Cited by 587
The impact of influenza epidemics on mortality: introducing a severity index.
Simonsen, L., Clarke, M. J., Williamson, G. D., Stroup, D. F., Arden, N. H., & Schonberger, L. B. (1997) · American Journal of Public Health · doi:10.2105/ajph.87.12.1944 · Cited by 587
Impact of Respiratory Virus Infections on Persons With Chronic Underlying Conditions
Glezen, W. P. (2000) · JAMA · doi:10.1001/jama.283.4.499 · Cited by 558
Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection
Mauad, T., Hajjar, L. A., Callegari, G. D., da Silva, L. F. F., Schout, D., Galas, F. R. B. G., Alves, V. A. F., Malheiros, D. M. A. C., Auler, J. O. C., Ferreira, A. F., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200909-1420oc · Cited by 547
A Single Mutation in the PB1-F2 of H5N1 (HK/97) and 1918 Influenza A Viruses Contributes to Increased Virulence
Conenello, G. M., Zamarin, D., Perrone, L. A., Tumpey, T. M., & Palese, P. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030141 · Cited by 525
Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates
Watt, J. P., Wolfson, L. J., O'Brien, K. L., Henkle, E., Deloria-Knoll, M., McCall, N., Lee, E., Levine, O. S., Hajjeh, R., Mulholland, K., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61203-4 · Cited by 501
Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice
Shahangian, A., Chow, E. K., Tian, X., Kang, J. R., Ghaffari, A., Liu, S. Y., Belperio, J. A., Cheng, G., & Deng, J. C. (2009) · Journal of Clinical Investigation · doi:10.1172/jci35412 · Cited by 479
STUDIES ON INFLUENZA IN THE PANDEMIC OF 1957-1958. II. PULMONARY COMPLICATIONS OF INFLUENZA*†
Louria, D. B., Blumenfeld, H. L., Ellis, J. T., Kilbourne, E. D., & Rogers, D. E. (1959) · Journal of Clinical Investigation · doi:10.1172/jci103791 · Cited by 479
Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1) - United States, May-August 2009.
Louie, J. K., Jean, C., Chen, T. H., Park, S., Ueki, R., Harper, T. J., Chmara, E., Myers, J. E., Stoppacher, R., Catanese, C., et al. (2009) · PubMed · Cited by 459
A critical function for CD200 in lung immune homeostasis and the severity of influenza infection
Snelgrove, R. J., Goulding, J., Didierlaurent, A. M., Lyonga, D., Vekaria, S., Edwards, L., Findlay, E. G., Sedgwick, J. D., Barclay, A. N., & Hussell, T. (2008) · Nature Immunology · doi:10.1038/ni.1637 · Cited by 454
2009 Pandemic Influenza A (H1N1)
Shieh, W.-J., Blau, D. M., Denison, A. M., DeLeon-Carnes, M., Adem, P., Bhatnagar, J., Sumner, J., Liu, L., Patel, M., Batten, B., et al. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.100115 · Cited by 429
Lethal Synergism between Influenza Virus and Streptococcus pneumoniae: Characterization of a Mouse Model and the Role of Platelet‐Activating Factor Receptor
McCullers, J. A., & Rehg, J. E. (2002) · The Journal of Infectious Diseases · doi:10.1086/341462 · Cited by 423
Self-citation
Global epidemiology of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA)
Mediavilla, J. R., Chen, L., Mathema, B., & Kreiswirth, B. N. (2012) · Current Opinion in Microbiology · doi:10.1016/j.mib.2012.08.003 · Cited by 400
Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection
Didierlaurent, A., Goulding, J., Patel, S., Snelgrove, R., Low, L., Bebien, M., Lawrence, T., van Rijt, L. S., Lambrecht, B. N., Sirard, J.-C., et al. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20070891 · Cited by 399
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections
Ghoneim, H. E., Thomas, P. G., & McCullers, J. A. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300014 · Cited by 394
Self-citation
Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States.
Rice, T. W., Rubinson, L., Uyeki, T. M., Vaughn, F. L., John, B. B., Miller, R. R., Higgs, E., Randolph, A. G., Smoot, B. E., & Thompson, B. T. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182416f23 · Cited by 391
Role of Neuraminidase in Lethal Synergism between Influenza Virus and Streptococcus pneumoniae
McCullers, J. A., & Bartmess, K. C. (2003) · The Journal of Infectious Diseases · doi:10.1086/368163 · Cited by 391
Self-citation
Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia
McAuley, J. L., Hornung, F., Boyd, K. L., Smith, A. M., McKeon, R., Bennink, J., Yewdell, J. W., & McCullers, J. A. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.09.001 · Cited by 389
Incidence and characteristics of viral community-acquired pneumonia in adults
Jennings, L., Anderson, T. P., Beynon, K. A., Chua, A., Laing, R. T. R., Werno, A., Young, S. A., Chambers, S. T., & Murdoch, D. R. (2007) · Thorax · doi:10.1136/thx.2006.075077 · Cited by 386
Deaths from Bacterial Pneumonia during 1918–19 Influenza Pandemic
Brundage, J. F., & Shanks, G. D. (2008) · Emerging Infectious Diseases · doi:10.3201/eid1408.071313 · Cited by 384
Pathogenesis of Pneumococcal Infection
TUOMANEN, E. I., AUSTRIAN, R. C., & Masure, H. R. (1995) · New England Journal of Medicine · doi:10.1056/nejm199505113321907 · Cited by 381
Respiratory Viruses Augment the Adhesion of Bacterial Pathogens to Respiratory Epithelium in a Viral Species- and Cell Type-Dependent Manner
Avadhanula, V., Rodriguez, C. A., DeVincenzo, J. P., Wang, Y., Webby, R. J., Ulett, G. C., & Adderson, E. E. (2006) · Journal of Virology · doi:10.1128/jvi.80.4.1629-1636.2006 · Cited by 357
IL-10 Is an Important Mediator of the Enhanced Susceptibility to Pneumococcal Pneumonia after Influenza Infection
van der Sluijs, K. F., van Elden, L. J. R., Nijhuis, M., Schuurman, R., Pater, J. M., Florquin, S., Goldman, M., Jansen, H. M., Lutter, R., & van der Poll, T. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.12.7603 · Cited by 338
Airway Epithelial Repair, Regeneration, and Remodeling after Injury in Chronic Obstructive Pulmonary Disease
Puchelle, É., Zahm, J., Tournier, J., & Coraux, C. (2006) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200605-126sf · Cited by 327
Influenza-Associated Pediatric Mortality in the United States: Increase of Staphylococcus aureus Coinfection
Finelli, L., Fiore, A., Dhara, R., Brammer, L., Shay, D. K., Kamimoto, L., Fry, A., Hageman, J., Gorwitz, R., Bresee, J., et al. (2008) · PEDIATRICS · doi:10.1542/peds.2008-1336 · Cited by 312
Viral Etiology of Severe Pneumonia Among Kenyan Infants and Children
Berkley, J. A. (2010) · JAMA · doi:10.1001/jama.2010.675 · Cited by 306
Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza
Palacios, G., Hornig, M., Cisterna, D., Savji, N., Bussetti, A. V., Kapoor, V., Hui, J., Tokarz, R., Briese, T., Baumeister, E., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008540 · Cited by 275
Role of Staphylococcus protease in the development of influenza pneumonia
Tashiro, M., Ciborowski, P. S., Klenk, H., Pulverer, G., & ROTT, R. (1987) · Nature · doi:10.1038/325536a0 · Cited by 272
Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes
Monsalvo, A. C., Batalle, J. P., López, M. G., Krause, J. C., Klemenc, J. M., Hernandez, J. Z., Maskin, B. C., Bugna, J., Rubinstein, C. J., Aguilar, L., et al. (2010) · Nature Medicine · doi:10.1038/nm.2262 · Cited by 265
NOTHING TO EAT BUT FOOD.
Nh, P., PHILIPS, M., & Wf, W. (1964) · PubMed · Cited by 263
SWINE INFLUENZA
Shope, R. E. (1931) · The Journal of Experimental Medicine · doi:10.1084/jem.54.3.349 · Cited by 248
Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice
Reading, P. C., Morey, L. S., Crouch, E. C., & Anders, E. M. (1997) · Journal of Virology · doi:10.1128/jvi.71.11.8204-8212.1997 · Cited by 244
Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease
Marks, L. R., Davidson, B. A., Knight, P. R., & Hakansson, A. P. (2013) · mBio · doi:10.1128/mbio.00438-13 · Cited by 240
Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages
Wang, J., Li, F., Sun, R., Gao, X., Wei, H., Li, L.-J., & Tian, Z. (2013) · Nature Communications · doi:10.1038/ncomms3106 · Cited by 239
Bacterial Pneumonia During the Hong Kong Influenza Epidemic of 1968-1969: Experience in a City-County Hospital
Schwarzmann, S. W. (1971) · Archives of Internal Medicine · doi:10.1001/archinte.1971.00310180053006 · Cited by 238
Adhesion Mechanisms of Staphylococci
Heilmann, C. (2011) · Advances in experimental medicine and biology · doi:10.1007/978-94-007-0940-9_7 · Cited by 234
Adherence of Type I Streptococcus pneumoniae to Tracheal Epithelium of Mice Infected with Influenza A/PR8 Virus
Plotkowski, M.-C., Puchelle, E., Beck, G., Jacquot, J., & Hannoun, C. (1986) · American Review of Respiratory Disease · doi:10.1164/arrd.1986.134.5.1040 · Cited by 231
Pandemic 2009 Influenza A in Argentina: A Study of 337 Patients on Mechanical Ventilation
Estenssoro, E., Ríos, F. G., Apezteguía, C., Reina, R., Neira, J., Ceraso, D. H., Orlandi, C., Valentini, R., Tiribelli, N., Brizuela, M., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/201001-0037oc · Cited by 230
Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1) - United States, May-August 2009.
(2009) · PubMed · Cited by 229
Influenza virus neuraminidase contributes to secondary bacterial pneumonia.
Peltola, V. T., Murti, K. G., & McCullers, J. A. (2005) · The Journal of Infectious Diseases · doi:10.1086/430954 · Cited by 219
Influenza Enhances Susceptibility to Natural Acquisition of and Disease due to Streptococcus pneumoniae in Ferrets
McCullers, J. A., McAuley, J. L., Browall, S., Iverson, A. R., Boyd, K. L., & Henriques Normark, B. (2010) · The Journal of Infectious Diseases · doi:10.1086/656333 · Cited by 218
Self-citation
Clinicopathologic Study of Thirty-Three Fatal Cases of Asian Influenza
Oseasohn, R., Adelson, L., & Kaji, M. (1959) · New England Journal of Medicine · doi:10.1056/nejm195903122601101 · Cited by 216
Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung
Small, C.-L., Shaler, C. R., McCormick, S., Jeyanathan, M., Damjanovic, D., Brown, E. G., Arck, P., Jordana, M., Kaushic, C., Ashkar, A. A., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902772 · Cited by 216
Recognition of Streptococcus pneumoniae by the innate immune system
Koppe, U., Suttorp, N., & Opitz, B. (2011) · Cellular Microbiology · doi:10.1111/j.1462-5822.2011.01746.x · Cited by 210
Immune Dysfunction and Bacterial Coinfections following Influenza
Metzger, D. W., & Sun, K. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301152 · Cited by 203
Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae
Smith, A. M., Adler, F. R., Ribeiro, R. M., Gutenkunst, R. N., McAuley, J., McCullers, J. A., & Perelson, A. S. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003238 · Cited by 201
Self-citation
BACTERIOLOGY AND HISTOPATHOLOGY OF THE RESPIRATORY TRACT AND LUNGS IN FATAL ASIAN INFLUENZA
Hers, J. F. P., Masurel, N., & Mulder, J. (1958) · The Lancet · doi:10.1016/s0140-6736(58)92404-8 · Cited by 201
Mortality Attributable to 9 Common Infections: Significant Effect of Influenza A, Respiratory Syncytial Virus, Influenza B, Norovirus, and Parainfluenza in Elderly Persons
van Asten, L., van den Wijngaard, C., van Pelt, W., van de Kassteele, J., Meijer, A., van der Hoek, W., Kretzschmar, M., & Koopmans, M. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis415 · Cited by 196
Type I Interferon Induction during Influenza Virus Infection Increases Susceptibility to Secondary Streptococcus pneumoniae Infection by Negative Regulation of γδ T Cells
Li, W., Moltedo, B., & Moran, T. M. (2012) · Journal of Virology · doi:10.1128/jvi.01269-12 · Cited by 191
Current concepts on the virulence mechanisms of meticillin-resistant Staphylococcus aureus
Watkins, R., David, M. Z., & Salata, R. A. (2012) · Journal of Medical Microbiology · doi:10.1099/jmm.0.043513-0 · Cited by 189
MORE ABOUT METHYSERGIDE
MACLENNAN, R. (1964) · The Lancet · doi:10.1016/s0140-6736(64)92683-2 · Cited by 178
In Vitro Assessment of Attachment Pattern and Replication Efficiency of H5N1 Influenza A Viruses with Altered Receptor Specificity
Chutinimitkul, S., van Riel, D. A. J., Munster, V. J., van den Brand, J. M. A., Rimmelzwaan, G. F., Kuiken, T., Osterhaus, A. D. M. E., Fouchier, R. A. M., & de Wit, E. (2010) · Journal of Virology · doi:10.1128/jvi.02737-09 · Cited by 171
Influenza virus primes mice for pneumonia from Staphylococcus aureus.
Iverson, A. R., Boyd, K. L., McAuley, J. L., Plano, L. R., Hart, M. E., & McCullers, J. A. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiq113 · Cited by 168
Self-citation
N-Linked Glycosylation Attenuates H3N2 Influenza Viruses
Vigerust, D. J., Ulett, K. B., Boyd, K. L., Madsen, J., Hawgood, S. B., & McCullers, J. A. (2007) · Journal of Virology · doi:10.1128/jvi.00769-07 · Cited by 167
Self-citation
PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology
McAuley, J., Chipuk, J. E., Boyd, K. L., Velde, N. V. D., Green, D. R., & McCullers, J. A. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001014 · Cited by 164
Self-citation
Effect of Antiviral Treatment on the Outcome of Secondary Bacterial Pneumonia after Influenza
McCullers, J. A. (2004) · The Journal of Infectious Diseases · doi:10.1086/421525 · Cited by 164
Self-citation
Nonenteric toxins of Staphylococcus aureus
Rogolsky, M. (1979) · Microbiological Reviews · doi:10.1128/mr.43.3.320-360.1979 · Cited by 159
Bacterial Complications of Respiratory Tract Viral Illness: A Comprehensive Evaluation
Falsey, A. R., Becker, K. L., Swinburne, A. J., Nylen, E. S., Formica, M. A., Hennessey, P. A., Criddle, M. M., Peterson, D. R., Baran, A., & Walsh, E. E. (2013) · Journal of Infectious Diseases · doi:10.1093/infdis/jit190 · Cited by 159
Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract
Parker, D., Martin, F. J., Soong, G., Harfenist, B. S., Aguilar, J. L., Ratner, A. J., Fitzgerald, K. A., Schindler, C., & Prince, A. S. (2011) · mBio · doi:10.1128/mbio.00016-11 · Cited by 152
Identifying the interaction between influenza and pneumococcal pneumonia using incidence data.
Shrestha, S., Foxman, B., Weinberger, D. M., Steiner, C., Viboud, C., & Rohani, P. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3005982 · Cited by 148
Impact of the introduction of pneumococcal conjugate vaccine on rates of community acquired pneumonia in children and adults
Nelson, J. C., Jackson, M. L., Yu, O., Whitney, C. G., Bounds, L., Bittner, R. C. L., Zavitkovsky, A., & Jackson, L. A. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.07.016 · Cited by 147
β-Arrestin 1 Participates in Platelet-Activating Factor Receptor-Mediated Endocytosis of Streptococcus pneumoniae
Radin, J. N., Orihuela, C. J., Murti, G., Guglielmo, C., Murray, P. J., & TUOMANEN, E. I. (2005) · Infection and Immunity · doi:10.1128/iai.73.12.7827-7835.2005 · Cited by 146
A Preliminary Study of Pneumonia Etiology Among Hospitalized Children in Kenya
Hammitt, L. L., Kazungu, S., Morpeth, S. C., Gibson, D. G., Mvera, B., Brent, A., Mwarumba, S., Onyango, C. O., Bett, A., Akech, D. O., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cir1071 · Cited by 144
Bacterial Pathogens and Death during the 1918 Influenza Pandemic
Chien, Y.-W., Klugman, K. P., & Morens, D. M. (2009) · New England Journal of Medicine · doi:10.1056/nejmc0908216 · Cited by 143
Lethal Synergism of 2009 Pandemic H1N1 Influenza Virus and Streptococcus pneumoniae Coinfection Is Associated with Loss of Murine Lung Repair Responses
Kash, J. C., Walters, K.-A., Davis, A. S., Sandouk, A., Schwartzman, L. M., Jagger, B. W., Chertow, D. S., Qi, L., Kuestner, R. E., Ozinsky, A., et al. (2011) · mBio · doi:10.1128/mbio.00172-11 · Cited by 143
Pneumococcal pneumonia and influenza: A deadly combination
Klugman, K. P., Chien, Y., & Madhi, S. A. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.06.007 · Cited by 139
Comparison of the Pathology Caused by H1N1, H5N1, and H3N2 Influenza Viruses
Guarner, J., & Falcón-Escobedo, R. (2009) · Archives of Medical Research · doi:10.1016/j.arcmed.2009.10.001 · Cited by 132
Impact of the 2009 influenza pandemic on pneumococcal pneumonia hospitalizations in the United States.
Weinberger, D. M., Simonsen, L., Jordan, R., Steiner, C., Miller, M., & Viboud, C. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir749 · Cited by 132
Structure and function of pneumolysin, the multifunctional, thiol‐activated toxin of Streptococcus pneumoniae
Boulnois, G. J., Paton, J. C., Mitchell, T. J., & Andrew, P. W. (1991) · Molecular Microbiology · doi:10.1111/j.1365-2958.1991.tb01969.x · Cited by 127
Pneumococcal Pneumonia
Dockrell, D. H., Whyte, M. K. B., & Mitchell, T. J. (2012) · CHEST Journal · doi:10.1378/chest.12-0210 · Cited by 125
Receptor specificity of adherence of Streptococcus pneumoniae to human type-II pneumocytes and vascular endothelial cells in vitro
Cundell, D. R., & TUOMANEN, E. I. (1994) · Microbial Pathogenesis · doi:10.1006/mpat.1994.1082 · Cited by 123
IMPORTANCE OF STAPHYLOCOCCUS AUREUS IN PNEUMONIA IN THE 1957 EPIDEMIC OF INFLUENZA A
Robertson, L., Caley, J. P., & Moore, J. (1958) · The Lancet · doi:10.1016/s0140-6736(58)90060-6 · Cited by 123
Lowering the Threshold of Lung Innate Immune Cell Activation Alters Susceptibility to Secondary Bacterial Superinfection
Goulding, J., Godlee, A., Vekaria, S., Hilty, M., Snelgrove, R. J., & Hussell, T. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir467 · Cited by 115
Streptococcus pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs
Koppe, U., Högner, K., Doehn, J.-M., Müller, H. C., Witzenrath, M., Gutbier, B., Bauer, S., Pribyl, T. M., Hammerschmidt, S., Lohmeyer, J., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1004143 · Cited by 113
Pandemic influenza: certain uncertainties
Morens, D. M., & Taubenberger, J. K. (2011) · Reviews in Medical Virology · doi:10.1002/rmv.689 · Cited by 110
Mortality Burden of the A/H1N1 Pandemic in Mexico: A Comparison of Deaths and Years of Life Lost to Seasonal Influenza
Charu, V., Chowell, G., Palacio Mejia, L. S., Echevarría-Zuno, S., Borja-Aburto, V. H., Simonsen, L., Miller, M. A., & Viboud, C. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir644 · Cited by 110
PULMONARY COMPLICATIONS OF INFLUENZA
Scadding, J. G. (1952) · The Lancet · doi:10.1016/s0140-6736(52)92362-3 · Cited by 107
Receptors in the Pseudomonas Aeruginosa Adherence to Injured and Repairing Airway Epithelium
de Bentzmann, S., Plotkowski, C., & Puchelle, É. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm/154.4_pt_2.s155 · Cited by 106
Pneumonia and Hong Kong influenza: a prospective study of the 1968-1969 epidemic
BISNO, A. L., GRIFFIN, J. P., VAN EPPS, K. A., NIELL, H. B., & RYTEL, M. W. (1971) · The American Journal of the Medical Sciences · doi:10.1097/00000441-197105000-00004 · Cited by 105
Decreased bacterial clearance from the lungs of mice following primary respiratory syncytial virus infection
Stark, J. M., Stark, M. A., Colasurdo, G. N., & LeVine, A. M. (2006) · Journal of Medical Virology · doi:10.1002/jmv.20631 · Cited by 105
Bacterial pneumonia during the Hong Kong influenza epidemic of 1968-1969.
Schwarzmann, S. W., Jl, A., Rj, S., & Marine, W. M. (1971) · PubMed · Cited by 104
Infection with Human Metapneumovirus Predisposes Mice to Severe Pneumococcal Pneumonia
Kukavica‐Ibrulj, I., Hamelin, M., Prince, G. A., Gagnon, C., Bergeron, Y., Bergeron, M. G., & Boivin, G. (2008) · Journal of Virology · doi:10.1128/jvi.01123-08 · Cited by 95
Incidence of respiratory pathogens in persons hospitalized with pneumonia in two provinces in Thailand
Olsen, S. J., Thamthitiwat, S., Chantra, S., Chittaganpitch, M., Fry, A. M., Simmerman, J. M., Baggett, H. C., Peret, T. C. T., Erdman, D. D., Benson, R. F., et al. (2010) · Epidemiology and Infection · doi:10.1017/s0950268810000646 · Cited by 92
Asian Influenza A in Boston, 1957-1958: II. Severe Staphylococcal Pneumonia Complicating Influenza
MARTIN, C. M. (1959) · A M A Archives of Internal Medicine · doi:10.1001/archinte.1959.00270040018002 · Cited by 91
Molecular pathogenesis of pneumococcal pneumonia
Jonathan, A. M. (2001) · Frontiers in bioscience · doi:10.2741/mccullers · Cited by 89
Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82
Alymova, I. V., Green, A. M., van de Velde, N. C., McAuley, J., Boyd, K. L., Ghoneim, H. E., & McCullers, J. A. (2011) · Journal of Virology · doi:10.1128/jvi.05872-11 · Cited by 89
Self-citation
Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?
Reichert, T., Chowell, G., Nishiura, H., Christensen, R., & McCullers, J. A. (2010) · BMC Infectious Diseases · doi:10.1186/1471-2334-10-5 · Cited by 86
Self-citation
Clinical and Epidemiologic Characteristics of Children Hospitalized With 2009 Pandemic H1N1 Influenza A Infection
Kumar, S., Havens, P. L., Chusid, M. J., Willoughby, R. E., Simpson, P. M., & Henrickson, K. J. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181d73e32 · Cited by 85
Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza
Karlström, Å., Heston, S. M., Boyd, K. L., TUOMANEN, E. I., & McCullers, J. A. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir522 · Cited by 85
Self-citation
Poly I:C Enhances Susceptibility to Secondary Pulmonary Infections by Gram-Positive Bacteria
Tian, X., Xu, F., Lung, W. Y., Meyerson, C., Ghaffari, A. A., Cheng, G., & Deng, J. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041879 · Cited by 77
Association of 2009 Pandemic Influenza A (H1N1) Infection and Increased Hospitalization With Parapneumonic Empyema in Children in Utah
Ampofo, K., Herbener, A., Blaschke, A. J., Heyrend, C., Poritz, M. A., Korgenski, K. E., Rolfs, R. T., Jain, S., Carvalho, M. D. G., Pimenta, F. C., et al. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181df2c70 · Cited by 73
Molecular Diagnostics for Detection of Bacterial and Viral Pathogens in Community‐Acquired Pneumonia
Nolte, F. S. (2008) · Clinical Infectious Diseases · doi:10.1086/591392 · Cited by 73
The Destruction of Type 2 Pneumocytes by Airborne Influenza PR8-A Virus; Its Effect on Surfactant and Lecithin Content of the Pneumonic Lesions of Mice
Loosli, C. G., Stinson, S. F., Ryan, D. P., Hertweck, M. S., Hardy, J. D., & Serebrin, R. (1975) · CHEST Journal · doi:10.1378/chest.67.2_supplement.7s · Cited by 70
Viral Coinfections in Children With Invasive Pneumococcal Disease
Techasaensiri, B., Techasaensiri, C., Mejías, A., McCracken, G. H., & Ramilo, O. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181cdafc2 · Cited by 70
Cellular and molecular mechanisms of bacterial adhesion to respiratory mucosa
Plotkowski, M. C., Bajolet-Laudinat, O., & Puchelle, É. (1993) · European Respiratory Journal · doi:10.1183/09031936.93.06060903 · Cited by 68
Preventing and Treating Secondary Bacterial Infections with Antiviral Agents
McCullers, J. A. (2011) · Antiviral Therapy · doi:10.3851/imp1730 · Cited by 65
Self-citation
The Role of Toll-like Receptors in Regulating the Immune Response against Respiratory Syncytial Virus
Klouwenberg, P. M. C. K., Tan, L., Werkman, W., van Bleek, G. M., & Coenjaerts, F. E. J. (2009) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v29.i6.40 · Cited by 64
Temporal Association Between Rhinovirus Circulation in the Community and Invasive Pneumococcal Disease in Children
Peltola, V. T., Heikkinen, T., Ruuskanen, O., Jartti, T. T., Hovi, T., Kilpi, T. M., & Vainionpää, R. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e318208ee82 · Cited by 63
Combined Infection of Mice with H. Influenzae and Influenza Virus by the Intranasal Route
Francis, T., & De Torregrosa, M. V. (1945) · Journal of Infectious Diseases · doi:10.1093/infdis/76.1.70 · Cited by 56
Pulmonary function in uncomplicated influenza.
JOHANSON, W. G., Pierce, A. K., & Sanford, J. P. (1969) · PubMed · doi:10.1164/arrd.1969.100.2.141 · Cited by 55
The innate immune rheostat: influence on lung inflammatory disease and secondary bacterial pneumonia
Hussell, T., & Cavanagh, M. (2009) · Biochemical Society Transactions · doi:10.1042/bst0370811 · Cited by 55
Coinfection with Staphylococcus aureus increases risk of severe coagulopathy in critically ill children with influenza A (H1N1) virus infection.
Nguyen, T., Kyle, U. G., Jaimon, N., Tcharmtchi, M. H., Coss-Bu, J. A., Lam, F., Teruya, J., & Loftis, L. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e318260c7f8 · Cited by 54
Etiology of Community-acquired Pneumonia in Hospitalized Children in Northern Taiwan
Chen, C., Lin, P.-Y., Tsai, M., Huang, C., Tsao, K., Wong, K.-S., Chang, L., Chiu, C., Lin, T., & Huang, Y.-C. (2012) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e31826eb5a7 · Cited by 54
Influenza Pandemic Epidemiologic and Virologic Diversity: Reminding Ourselves of the Possibilities
Kasowski, E. J., Garten, R. J., & Bridges, C. B. (2010) · Clinical Infectious Diseases · doi:10.1093/cid/ciq010 · Cited by 54
Trends and Epidemics of Influenza and Pneumonia, 1918-1951
Collins, S. D., & Lehmann, J. (1951) · Public Health Reports (1896-1970) · doi:10.2307/4587915 · Cited by 54
Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lung
Wong, S. M. S., Bernui, M., Shen, H., & Akerley, B. J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1311217110 · Cited by 53
Mortality Risk Factors During the 1918–1919 Influenza Pandemic in the Australian Army
Shanks, G. D., MacKenzie, A., McLaughlin, R., Waller, M., Dennis, P. N. J., Lee, S., & Brundage, J. F. (2010) · The Journal of Infectious Diseases · doi:10.1086/652868 · Cited by 53
Current concepts in host–microbe interaction leading to pneumococcal pneumonia
Vernatter, J., & Pirofski, L. (2013) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e3283608419 · Cited by 52
POST-MORTEM FINDINGS IN 46 INFLUENZA DEATHS
Giles, C., & Shuttleworth, E. M. (1957) · The Lancet · doi:10.1016/s0140-6736(57)90180-0 · Cited by 52
Streptococcus pneumoniae nasopharyngeal colonization induces type I interferons and interferon-induced gene expression
Joyce, E. A., Popper, S. J., & Falkow, S. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-404 · Cited by 51
Human Metapneumovirus Inhibits IFN-β Signaling by Downregulating Jak1 and Tyk2 Cellular Levels
Ren, J., Kolli, D., Liu, T., Xu, R., Garofalo, R. P., Casola, A., & Bao, X. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024496 · Cited by 50
Inactivated and live, attenuated influenza vaccines protect mice against influenza:Streptococcus pyogenes super-infections
Chaussee, M. S., Sandbulte, H. R., Schuneman, M. J., DePaula, F. P., Addengast, L. A., Schlenker, E. H., & Huber, V. C. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.03.031 · Cited by 49
The Novel Parainfluenza Virus Hemagglutinin-Neuraminidase Inhibitor BCX 2798 Prevents Lethal Synergism between a Paramyxovirus and Streptococcus pneumoniae
Alymova, I. V., Portner, A., Takimoto, T., Boyd, K. L., Babu, Y. S., & McCullers, J. A. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.1.398-405.2005 · Cited by 49
Self-citation
Respiratory syncytial virus infection augments NOD 2 signaling in an IFN ‐β‐dependent manner in human primary cells
Vissers, M., Remijn, T., Oosting, M., de Jong, D. J., Diavatopoulos, D. A., Hermans, P. W. M., & Ferwerda, G. (2012) · European Journal of Immunology · doi:10.1002/eji.201242396 · Cited by 48
Cell Receptors for Influenza a Viruses and the Innate Immune Response
Ramos, I., & Fernández-Sesma, A. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00117 · Cited by 48
Do specific virus–bacteria pairings drive clinical outcomes of pneumonia?
McCullers, J. A. (2012) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12093 · Cited by 47
Self-citation
DEATH FROM ASIATIC INFLUENZA IN THE NETHERLANDS
Hers, J. F. P., Goslings, W. R. O., Masurel, N., & Mulder, J. (1957) · The Lancet · doi:10.1016/s0140-6736(57)92066-4 · Cited by 46
Epidemiology and clinical characteristics of hospitalized patients with pandemic influenza A (H1N1) 2009 infections: the effects of bacterial coinfection.
Dhanoa, A., Fang, N. C., Hassan, S. S., Kaniappan, P., & Rajasekaram, G. (2011) · Virology Journal · doi:10.1186/1743-422x-8-501 · Cited by 45
What Really Happened during the 1918 Influenza Pandemic? The Importance of Bacterial Secondary Infections
Brundage, J. F., & Shanks, G. D. (2007) · The Journal of Infectious Diseases · doi:10.1086/522355 · Cited by 43
Naturally Occurring Swine Influenza A Virus PB1-F2 Phenotypes That Contribute to Superinfection with Gram-Positive Respiratory Pathogens
Weeks, J. N., Hurtig, H. R., Iverson, A., Schuneman, M. J., Webby, R. J., McCullers, J. A., & Huber, V. C. (2012) · Journal of Virology · doi:10.1128/jvi.00369-12 · Cited by 42
Self-citation
Modifications of lung clearance mechanisms by acute influenza A infection.
Levandowski, R. A., Gerrity, T. R., & Garrard, C. S. (1985) · PubMed · Cited by 41
Asian influenza A in Boston, 1957-1958
Cm, M. (1959) · JAMA Internal Medicine · Cited by 41
Effect of the 2009 Influenza A(H1N1) Pandemic on Invasive Pneumococcal Pneumonia
Fleming-Dutra, K. E., Taylor, T., Link‐Gelles, R., Garg, S., Jhung, M. A., Finelli, L., Jain, S., Shay, D. K., Chaves, S. S., Baumbach, J., et al. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit008 · Cited by 39
Hypersusceptibility to Invasive Pneumococcal Infection in Experimental Sickle Cell Disease Involves Platelet‐Activating Factor Receptor
Miller, M. L., Gao, G., Pestina, T. I., Persons, D., & TUOMANEN, E. I. (2007) · The Journal of Infectious Diseases · doi:10.1086/510626 · Cited by 36
National influenza experience in the USA, 1968-69.
Sharrar, R. G. (1969) · Europe PMC (PubMed Central) · Cited by 35
Effect of uncomplicated, presumptive influenza on the diffusing capacity of the lung.
Horner, G. J., & Gray, F. D. (1973) · PubMed · doi:10.1164/arrd.1973.108.4.866 · Cited by 35
Global Gene Expression Profiling in Infants With Acute Respiratory Syncytial Virus Broncholitis Demonstrates Systemic Activation of Interferon Signaling Networks
Bucasas, K. L., Mian, A. I., Demmler‐Harrison, G. J., Caviness, A. C., Piedra, P. A., Franco, L. M., Shaw, C. A., Zhai, Y., Wang, X., Bray, M. S., et al. (2012) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e318278b4b3 · Cited by 32
Influenza-associated mortality among children - United States: 2007-2008
Peebles, P. J., Dhara, R., Brammer, L., Fry, A. M., & Finelli, L. (2010) · Influenza and Other Respiratory Viruses · doi:10.1111/j.1750-2659.2010.00166.x · Cited by 31
ASIAN INFLUENZA IN THE UNITED STATES
LANGMUIR, A. D. (1958) · Annals of Internal Medicine · doi:10.7326/0003-4819-49-3-483 · Cited by 30
Influenza-Pneumonia Mortality in a Group of about 95 Cities in the United States, 1920-1929
Collins, S. D. (1930) · Public Health Reports (1896-1970) · doi:10.2307/4579562 · Cited by 30
Streptococcus pneumoniae produces at least two distinct enzymes with neuraminidase activity: cloning and expression of a second neuraminidase gene in Escherichia coli
Cámara, M., Mitchell, T. J., Andrew, P. W., & Boulnois, G. J. (1991) · Infection and Immunity · doi:10.1128/iai.59.8.2856-2858.1991 · Cited by 30
Severe Influenza Virus Pneumonia in the Pandemic of 1968-1969
Burk, R. F. (1971) · Archives of Internal Medicine · doi:10.1001/archinte.1971.00310180138019 · Cited by 28
ASIAN INFLUENZA IN THE UNITED STATES, 1957–19581
Trotter, Y., Dunn, F. L., Drachman, R. H., Henderson, D. A., Pizzi, M., & Langmuir, A. D. (1959) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a120063 · Cited by 28
Low but highly variable mortality among nurses and physicians during the influenza pandemic of 1918-1919
Shanks, G. D., MacKenzie, A., Waller, M., & Brundage, J. F. (2011) · Influenza and Other Respiratory Viruses · doi:10.1111/j.1750-2659.2010.00195.x · Cited by 27
Mortality in the 1957-58 Influenza Epidemic
Dauer, C. C. (1958) · Public Health Reports (1896-1970) · doi:10.2307/4590246 · Cited by 22
GAS-ANALYTICAL STUDIES IN SEVERE PNEUMONIA OBSERVATIONS DURING THE 1957 INFLUENZA EPIDEMIC
HERZOG, H. (1959) · The Lancet · doi:10.1016/s0140-6736(59)92351-7 · Cited by 22
Transcriptional adaptation of pneumococci and human pharyngeal cells in the presence of a virus infection
Mlacha, S. Z. K., Peret, T. C. T., Kumar, N., Romero‐Steiner, S., Hotopp, J. C. D., Ishmael, N., Grinblat-Huse, V., Riley, D. R. J., Erdman, D. D., Carlone, G. M., et al. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-378 · Cited by 21
Influenza A virus‐mediated priming enhances cytokine secretion by human dendritic cells infected with S treptococcus pneumoniae
Kuri, T., Smed‐Sörensen, A., Thomas, S., Hedestam, G. B. K., Normark, S. J., Henriques‐Normark, B., McInerney, G. M., & Plant, L. (2013) · Cellular Microbiology · doi:10.1111/cmi.12122 · Cited by 19
Epidemic Influenza
Sisley, R., & Sisley, R. (2012) · Cited by 18
Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses
Smith, A. M., & McCullers, J. A. (2013) · Virus Research · doi:10.1016/j.virusres.2013.02.012 · Cited by 17
Self-citation
Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice
Ludewick, H. P., Aerts, L., Hamelin, M., & Boivin, G. (2011) · Journal of General Virology · doi:10.1099/vir.0.030825-0 · Cited by 16
Inhalation Experiments on Influenza and Pneumonia, and on the Importance of Spray-Borne Bacteria in Respiratory Infections
Wherry, W. B., & Butterfield, C. T. (1920) · The Journal of Infectious Diseases · doi:10.1093/infdis/27.4.315 · Cited by 12
Translation of Selected Passages from De L’Auscultation Médiate
Packard, F. (1923) · PubMed Central · Cited by 11
BACTERIA AND INFLUENZA
Jevons, M. P., Taylor, C. E. D., & Williams, R. E. O. (1957) · The Lancet · doi:10.1016/s0140-6736(57)90024-7 · Cited by 5
Translation of Selected Passages from “De L’Auscultation Mediate.”
(1923) · Journal of The Royal Naval Medical Service · doi:10.1136/jrnms-9-229a · Cited by 3
ALDOSTERONE EXCRETION IN NORMAL PREGNANCY AND PRE-ECLAMPSIA
Sophian, J. (1959) · The Lancet · doi:10.1016/s0140-6736(59)92029-x · Cited by 2
BACTERIA and influenza.
(1957) · PubMed · Cited by 1

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Cheung, G. Y. C., Bae, J. S., & Otto, M. J. (2021) · Virulence · doi:10.1080/21505594.2021.1878688 · Cited by 1,554
Streptococcus pneumoniae: transmission, colonization and invasion
Weiser, J. N., Ferreira, D. M., & Paton, J. C. (2018) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0001-8 · Cited by 1,162
Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study
Schauwvlieghe, A. F. A. D., Rijnders, B. J. A., Philips, N., Verwijs, R., Vanderbeke, L., Van Tienen, C., Lagrou, K., Verweij, P. E., Van de Veerdonk, F. L., Gommers, D., et al. (2018) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(18)30274-1 · Cited by 886
Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa
Uyeki, T. M., Bernstein, H. H., Bradley, J. S., Englund, J. A., File, T. M., Fry, A. M., Gravenstein, S., Hayden, F. G., Harper, S. A., Hirshon, J. M., et al. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/ciy866 · Cited by 844
The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis.
Klein, E. Y., Monteforte, B., Gupta, A., Jiang, W., May, L., Hsieh, Y., & Dugas, A. (2016) · Influenza and Other Respiratory Viruses · doi:10.1111/irv.12398 · Cited by 574

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Authors: McCullers, J. A.
Affiliations: St. Jude Children's Research Hospital (US)
Corresponding author: McCullers, Jonathan A.
Venue: Nature Reviews Microbiology
Publisher: Springer Science and Business Media LLC
Published: 2014-03-03
Volume: 12
Issue: 4
Pages: 252-262
ISSN: 1740-1526 (ISSN-L)
1740-1534
DOI: 10.1038/nrmicro3231
OpenAlex: W2076298858
Semantic Scholar: 6eb404402ff0d8d99a34a2cf97e6a417c97de878
Cited by: 722
References: 167
Citations by year: 2026: 46 · 2025: 42 · 2024: 56 · 2023: 60 · 2022: 67 · 2021: 91 · 2020: 71 · 2019: 70 · 2018: 58 · 2017: 38 · 2016: 56 · 2015: 42 · 2014: 23
FWCI: 7.07
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Nature Reviews Microbiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
Keywords: influenza virus, bacterial co-infection, secondary bacterial infection, lung, virulence factors, immune dysregulation, host-pathogen interaction, immune-mediated pathology, pandemic influenza
MeSH terms: Bacterial Infections, Humans, Influenza, Human, Lung, Pneumonia, Viral, Superinfection, Pneumonia, Bacterial, Coinfection

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The co-pathogenesis of influenza viruses with bacteria in the lung.

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